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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Placebo Laser Clear all
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Can Pregabalin Reduce the Frequency and Severity of Dry Eye Symptoms After Laser-assisted in Situ Keratomileusis?

NCT02701764
View directory record Official record
Conditions
Dry Eye
Interventions
Pregabalin, Placebo
Drug
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 65 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Nov 13, 2019 · Synced Sep 25, 2026, 2:47 PM EDT
Completed Not applicable Interventional Results available

Non-Damaging Photothermal Therapy of Non-exudative Age Related Macular Degeneration

NCT02569892
View directory record Official record
Conditions
Macular Degeneration, Retinal Drusen
Interventions
Pascal Retinal Laser Photocoagulator
Device
Lead sponsor
Stanford University
Other
Eligibility
60 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Oct 27, 2021 · Synced Sep 25, 2026, 2:47 PM EDT
Recruiting Phase 3 Interventional

Testing Laser Therapy for Treatment of Vaginal Dryness in Survivors of Breast Cancer, The Revitalize Trial

NCT05379153
View directory record Official record
Conditions
Vaginal Atrophy, Breast Carcinoma
Interventions
Laser Therapy, Sham Intervention, Questionnaire Administration, Quality of Life Assessment
Device · Other
Lead sponsor
Alliance for Clinical Trials in Oncology
Other
Eligibility
22 Years and older · Female only
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Ann Arbor, Michigan • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Sep 25, 2026, 2:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of LLLT/Music for Smoking Cessation

NCT04830384
View directory record Official record
Conditions
Nicotine Dependence, Cigarettes
Interventions
Fully Active, LLLT Only, Music Only, Placebo
Device
Lead sponsor
Freedom Laser, Inc.
Industry
Eligibility
21 Years to 65 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Mendham, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 4, 2021 · Synced Sep 25, 2026, 2:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

TR-987 vs. Placebo Following Fractionated CO2 Laser Resurfacing of the Chest

NCT02681224
View directory record Official record
Conditions
Exposure Laser
Interventions
TR987 Gel with Silon Bandage, TR987 without Silon Bandage, Placebo Gel with Silon Bandage, Placebo Gel without Silon Bandage
Other
Lead sponsor
Goldman, Butterwick, Fitzpatrick and Groff
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 28, 2017 · Synced Sep 25, 2026, 2:47 PM EDT
Terminated Not applicable Interventional Results available

The Effect of Low-Level Laser Stimulation on Hearing Thresholds

NCT01820416
View directory record Official record
Conditions
Hearing Loss
Interventions
Low-level Laser Therapy, Placebo Comparator: Disabled Laser
Radiation · Other
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 75 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 31, 2017 · Synced Sep 25, 2026, 2:47 PM EDT
Completed Phase 2 Interventional

Study of Acute Peripheral Vascular Effects, Safety and Tolerability in Subjects With Raynaud's Phenomenon Secondary to Systemic Sclerosis

NCT02228850
View directory record Official record
Conditions
Raynaud's Phenomenon Secondary to Systemic Sclerosis
Interventions
Alprostadil, Placebo
Drug · Other
Lead sponsor
NexMed (U.S.A.), Inc. (subsidiary of Apricus Biosciences, Inc.)
Industry
Eligibility
18 Years to 79 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
4
States / cities
Encinitas, California • Ann Arbor, Michigan • Cleveland, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 21, 2016 · Synced Sep 25, 2026, 2:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cranial Laser Reflex Technique for Hamstring Function

NCT03044106
View directory record Official record
Conditions
Hamstring Injury, Muscle Tone Increased, Muscle Pain, Muscle Weakness
Interventions
CLRT
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 35 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 11, 2019 · Synced Sep 25, 2026, 2:47 PM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Role of Autophagy in Type 2 Diabetes Microvascular Dysfunction

NCT05593549
View directory record Official record
Conditions
Type 2 Diabetes, Healthy Aging
Interventions
Trehalose, Placebo
Drug
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2029
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 29, 2025 · Synced Sep 25, 2026, 2:47 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Efficacy Study of GLYC-101 to Evaluate Outcomes After Laser Ablation

NCT00792688
View directory record Official record
Conditions
Wounds
Interventions
GLYC-101 Gel (0.1%), GLYC-101 Gel (1.0%), GLYC-101 Placebo
Drug
Lead sponsor
TR Therapeutics
Industry
Eligibility
25 Years to 70 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Beverly Hills, California
Source: ClinicalTrials.gov public record
Updated Oct 27, 2021 · Synced Sep 25, 2026, 2:47 PM EDT
Completed Not applicable Interventional

MonaLisa Touch Laser for the Treatment of Vulvar Lichen Sclerosus

NCT03665584
View directory record Official record
Conditions
Lichen Sclerosus
Interventions
FxCO2 Laser, Sham Laser
Device
Lead sponsor
Center for Vulvovaginal Disorders
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Nov 11, 2020 · Synced Sep 25, 2026, 2:47 PM EDT
Terminated Not applicable Interventional Results available

Comparing Acular LS and Pred Forte in Reducing Post-selective Laser Trabeculoplasty Anterior Chamber Flare and Cells

NCT00478036
View directory record Official record
Conditions
Open Angle Glaucoma
Interventions
Acular LS, Pred Forte, Refresh Tears
Drug · Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2014
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 6, 2016 · Synced Sep 25, 2026, 2:47 PM EDT
Terminated Not applicable Interventional Results available

Efficacy Study of the Application of Low Level Laser Light to Treat Venous Stasis Ulcers

NCT01376050
View directory record Official record
Conditions
Venous Stasis Ulcer
Interventions
Erchonia ML Scanner (MLS), Placebo Laser
Device
Lead sponsor
Erchonia Corporation
Industry
Eligibility
40 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Dec 10, 2015 · Synced Sep 25, 2026, 2:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study of Low Level Laser Therapy and Word Recognition in Hearing Impaired Individuals

NCT00787189
View directory record Official record
Conditions
Sensorineural Hearing Loss
Interventions
The Hearing Laser, Placebo Laser
Device
Lead sponsor
Erchonia Corporation
Industry
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated May 27, 2021 · Synced Sep 25, 2026, 2:47 PM EDT
Completed Not applicable Interventional Results available

A Comparison of Pregabalin (Lyrica®) to Placebo in Pain Relief After Photorefractive Keratectomy (PRK) Surgery

NCT01097577
View directory record Official record
Conditions
Postoperative Pain
Interventions
pregabalin, Placebo
Drug
Lead sponsor
59th Medical Wing
Federal
Eligibility
21 Years and older
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
Lackland Air Force Base, Texas
Source: ClinicalTrials.gov public record
Updated Oct 27, 2020 · Synced Sep 25, 2026, 2:47 PM EDT
Completed Not applicable Interventional

Treatment Trial Using Low Level Laser Therapy (LLLT) for Treatment of Chemotherapy Induced Peripheral Neuropathy

NCT01006408
View directory record Official record
Conditions
Peripheral Neuropathy
Interventions
Low Level Laser, Placebo followed by Low Level Laser
Procedure
Lead sponsor
Legacy Health System
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 18, 2012 · Synced Sep 25, 2026, 2:47 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Efficacy Of Tocotrienol a Natural Vitamin E In Biopsy Wound

NCT01579227
View directory record Official record
Conditions
Scar
Interventions
Topical Tocotrienol (TCT), Oral Tocotrienol Capsules (TCT), Tamoxifen Cream, Placebo cream, placebo capsule
Device · Dietary Supplement
Lead sponsor
Chandan K Sen
Other
Eligibility
18 Years to 50 Years
Enrollment
101 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 28, 2018 · Synced Sep 25, 2026, 2:47 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Transvaginal Low-level Laser Therapy to Improve Pelvic Pain and Sexual Function in Patients with Endometriosis.

NCT05540353
View directory record Official record
Conditions
Endometriosis, Dyspareunia, Pelvic Pain
Interventions
Transvaginal photobiomodulation, Sham therapy
Device
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
6
States / cities
Washington D.C., District of Columbia • Mitchellville, Maryland • Rockville, Maryland + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 18, 2025 · Synced Sep 25, 2026, 2:47 PM EDT
Terminated Not applicable Interventional Results available

New Therapy of Laryngeal Papilloma In Children

NCT00591305
View directory record Official record
Conditions
Papilloma
Interventions
diindolylmethane (DIM), 585 nm pulsed dye laser
Dietary Supplement · Device
Lead sponsor
Boston University
Other
Eligibility
10 Years to 21 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 17, 2017 · Synced Sep 25, 2026, 2:47 PM EDT
Terminated Not applicable Interventional Results available

Photobiomodulation for the Management of Temporomandibular Disorder Pain

NCT04415281
View directory record Official record
Conditions
Pain Related to TMD
Interventions
THOR® laser system, sham THOR® laser system
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 11, 2023 · Synced Sep 25, 2026, 2:47 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Perio. Maint. With Diode LBR

NCT05276817
View directory record Official record
Conditions
Chronic Periodontitis
Interventions
Epic Diode, HP, Sham
Device · Drug
Lead sponsor
Biolase Inc
Industry
Eligibility
30 Years and older
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
San Mateo, California
Source: ClinicalTrials.gov public record
Updated May 2, 2023 · Synced Sep 25, 2026, 2:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Study of Nutritional Supplementation in Altering Ecchymosis, Erythema and Health Outcomes Associated With Aesthetic Procedures

NCT01919359
View directory record Official record
Conditions
Ecchymosis and Erythema Commonly Associated With Soft Tissue Filler Injections
Interventions
Multizyme Cellular Vitality Cyruta Plus SHEP
Dietary Supplement
Lead sponsor
DeNova Research
Other
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 31, 2018 · Synced Sep 25, 2026, 2:47 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

The Effect of Topical Anesthetics on Patients' Pain and Operative Experience During Treatment With QSwitched Laser

NCT02427724
View directory record Official record
Conditions
Lentigo
Interventions
lidocaine 2.5%/prilocaine 2.5% topical anesthetic, lidocaine 7%/tetracaine 7% topical anesthetic, placebo vehicle, Q-switched 532nm Laser
Drug · Device
Lead sponsor
Northwestern University
Other
Eligibility
25 Years to 65 Years · Female only
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Sep 25, 2026, 2:47 PM EDT
Terminated Not applicable Interventional Results available

Efficacy of the Erchonia Corporation THL™ for Providing Relief of Tinnitus Symptoms

NCT05374421
View directory record Official record
Conditions
Tinnitus
Interventions
Erchonia® THL™, Placebo Laser
Device
Lead sponsor
Erchonia Corporation
Industry
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Concord, California
Source: ClinicalTrials.gov public record
Updated Mar 11, 2024 · Synced Sep 25, 2026, 2:47 PM EDT