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Conditions: Pain, Postoperative, Anterior Cruciate Ligament Injuries, Analgesics, Opioid
Interventions: IPACK, PLACEBO; Drug
Lead sponsor: Loyola University; Other
Eligibility: 16 Years and older
Enrollment: 78 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Maywood, Illinois

Conditions: Total Knee Arthroplasty
Interventions: Ambulatory continuous femoral nerve block for 100 hours; Procedure
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years to 75 Years
Enrollment: 81 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 3
States / cities: Berkeley, California • San Diego, California • Gainesville, Florida

Conditions: Hip Osteoarthritis, Primary Total Hip Arthroplasty, Pain
Interventions: Suprainguinal fascia iliaca (SIFI) block, Sham block, Ropivacaine, Saline; Procedure · Drug
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Foot and Ankle Procedures
Interventions: Dexamethasone, Saline; Drug
Lead sponsor: Cedars-Sinai Medical Center; Other
Eligibility: 18 Years to 90 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Anesthesia, Local, Shoulder Surgery
Interventions: saline, Dexamethasone, ropivacaine, Bupivacaine; Drug
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years to 75 Years
Enrollment: 218 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Internal Derangement of Knee
Interventions: 0.25% Bupivacaine, Normal Saline; Drug
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older
Enrollment: 68 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Arthroplasty, Replacement, Knee, Nerve Block
Interventions: Adductor Canal Nerve Block Catheter, Adductor Canal Nerve Block Sham Catheter, Bupivacaine; Device · Drug
Lead sponsor: University of Chicago; Other
Eligibility: Up to 85 Years
Enrollment: 165 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Joint Disease, Pain, Acute, Pain, Chronic
Interventions: Cymbalta, Placebo; Drug · Other
Lead sponsor: Hospital for Special Surgery, New York; Other
Eligibility: 25 Years to 75 Years
Enrollment: 160 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: New York, New York

Conditions: Anesthesia, Local, Phrenic Nerve Paralysis, Upper Extremity Injury, Phrenic Nerve Palsy on the Left, Phrenic Nerve Palsy on the Right
Interventions: Normal saline injected via interscalene nerve catheter, Placebo; Procedure · Other
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 43 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Pain, Sciatic Block
Interventions: Placebo, Dexamethasone 4 mg, Dexamethasone 8 mg; Drug
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 18 Years to 64 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Mitral Valve Insufficiency
Interventions: Paravertebral Block, Placebo Comparator; Other
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 90 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: New York, New York

Conditions: Stress (Psychology), Stress, Healthy Adult Female Participants, Stress, Psychologic, Stress, Psychological Cumulative, Stress, Physiological, Stress Response, Stress Levels, Stress Perception
Interventions: Intramuscular injection, OnabotulinumtoxinA (Botox®) Injections, Sodium Chloride; Procedure · Drug · Other
Lead sponsor: Center for Advanced Facial Plastic Surgery; Other
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 4 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Beverly Hills, California

Conditions: Postural Tachycardia Syndrome
Interventions: Stellate ganglion block, Sham injection of saline, Ropivacaine, Normal saline; Procedure · Drug
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 2
States / cities: Stanford, California

Conditions: Pain
Interventions: Obturator Nerve Block, Ropivacaine, Placebo Saline; Procedure · Drug
Lead sponsor: Benaroya Research Institute; Other
Eligibility: 18 Years to 65 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Vocal Cord Disease, Vocal Cord Polyp, Vocal Cord Cyst
Interventions: Superior laryngeal nerve block - Intervention (Bupivacaine and triamcinolone acetonide suspension), Superior laryngeal nerve block - Placebo (saline); Drug
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 18 Years and older
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Newark, New Jersey

Conditions: Anterior Cruciate Ligament (ACL) Tear, Sports Injuries in Children, Analgesia, Pain, Postoperative
Interventions: Ropivacaine 0.2% Injectable Solution; Drug
Lead sponsor: Texas Scottish Rite Hospital for Children; Other
Eligibility: 13 Years to 21 Years
Enrollment: 160 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Frisco, Texas

Conditions: Skin Cancer Face, Skin Cancer Scalp
Interventions: Nerve Block, Placebo Nerve Block; Other
Lead sponsor: Abramson Cancer Center at Penn Medicine; Other
Eligibility: 18 Years and older
Enrollment: 132 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Pain
Interventions: Gabapentin, Placebos; Drug
Lead sponsor: Texas Health Resources; Other
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: Ends 2007
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Spinal Cord Injuries
Interventions: Bladder chemodenervation (Botox), Bladder Sham (Saline) Injection Procedure; Drug · Procedure
Lead sponsor: University of Washington; Other
Eligibility: 18 Years to 65 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Pelvic Organ Prolapse, Surgery, Postoperative Pain
Interventions: Dexamethasone, Bupivacaine, Bilateral Pudendal Nerve Block, Bilateral Levator Ani Muscle Injection, Saline; Drug · Procedure
Lead sponsor: Lauren Giugale, MD; Other
Eligibility: 18 Years and older · Female only
Enrollment: 79 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Peripheral Nerve Stimulation, Genicular Nerves, Chronic Knee Pain
Interventions: PNS therapy, Triamcinolone, Bupivacaine, Placebo; Other · Drug
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Wounds and Injuries, Rib Fractures
Interventions: Ketamine, Placebo, Intercostal Nerve Block, Acetaminophen, Ibuprofen, Pantoprazole, Methocarbamol, Opioid; Drug · Procedure
Lead sponsor: Medical College of Wisconsin; Other
Eligibility: 18 Years and older
Enrollment: 153 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Milwaukee, Wisconsin

Conditions: Hip Fractures, Analgesia, Opioid Use, Pain, Postoperative
Interventions: Cephalomedullary nailing of extracapsular hip fracture, cephalomedullary nail, Regional Anesthetics; Procedure · Device · Drug
Lead sponsor: Montefiore Medical Center; Other
Eligibility: 60 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: New York, New York

Conditions: Phantom Limb Pain
Interventions: Perineural infusion [continuous peripheral nerve block(s)]; Drug
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 144 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2020
U.S. locations: 4
States / cities: Palo Alto, California • San Diego, California • Bethesda, Maryland + 1 more

Search by objective public record fields.

IPACK on Early Pain Scores After ACL Reconstruction

Effect of Ambulatory Continuous Femoral Nerve Blocks on Readiness-for-Discharge Following Total Knee Replacement

Suprainguinal Fascia Iliaca (SIFI) Block Improves Analgesia Following Total Hip Arthroplasty

Efficacy of Popliteal Nerve Blocks With and Without Dexamethasone on the Duration of Analgesia for Foot & Ankle Surgery

The Effect of Dexamethasone on the Duration of Interscalene Nerve Blocks With Ropivacaine or Bupivacaine

Infrapatellar Nerve Block for Post-operative Knee Arthroscopy Pain Control

Epidural Catheter With or Without Adductor Canal Nerve Block for Postoperative Analgesia Following Total Knee Arthroplasty

Effect of Duloxetine on Opioid Use After Total Knee Arthroplasty

Interscalene Brachial Plexus Block Washout to Reverse Inadvertent Phrenic Nerve Blockade

Trial Comparing Duration of Analgesia After Popliteal Fossa Sciatiac Nerve Block With Ropivacaine 0.5% When Combined With Placebo, Dexamethasone 4mg or Dexamethasone 8 mg

The Use of Paravertebral Block for Cardiac Surgery

Impact of OnabotulinumtoxinA (BOTOX®) on Stress

Ultrasound Guided Stellate Ganglion Block in Postural Tachycardia Syndrome

Ultrasound-Guided Obturator Nerve Block for Ambulatory Hip Arthroscopy

Effect of Superior Laryngeal Nerve Blocks on Patient Outcomes in Laryngeal Surgery

Evaluation of Pain Management After Surgery When Using Nerve Blocks in the Pediatric Population

Comparing Numbing Techniques in Mohs Micrographic Surgery

Preanalgesic Effect of Gabapentin in Total Knee Repair

Early BOTOX After Spinal Cord Injury

Preoperative Levator Ani Muscle Injection and Pudendal Nerve Block for Pain Control After Vaginal Reconstructive Surgery

Peripheral Nerve Stimulation of Genicular Nerves Versus Conventional Therapy With Intra-articular Steroid Injection for Chronic Knee Pain: A Prospective, Randomized Pilot Study

Ketamine Infusion Therapy for the Management of Acute Pain in Adult Rib Fracture Patients

Postop Pain Control in Hip Fracture Surgery: Fascia Iliaca Compartment Block Versus Fracture Block

Treating Phantom Limb Pain Using Continuous Peripheral Nerve Blocks: A Department of Defense Funded Multicenter Study