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Showing 1–24 of 47 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Not listed Not applicable Interventional Accepts healthy volunteers

Effects of Neo40(TM) With Caffeine on Cycling Time Trial Performance

NCT01710761
Conditions
Healthy
Interventions
Placebo, Nitrate supplement with caffeine
Dietary Supplement
Lead sponsor
University of Texas at Austin
Other
Eligibility
21 Years to 49 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Austin, Texas
Completed Early Phase 1 Interventional Results available

Using MASL to Combat Oral Cancer

NCT04188665
Conditions
Squamous Cell Carcinoma of Head and Neck
Interventions
MASL, Placebo
Drug · Other
Lead sponsor
Rowan University
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
4
States / cities
Newark, New Jersey • Stratford, New Jersey
Conditions
COVID-19
Interventions
chlorine dioxide, zinc acetate, Famotidine, placebo, lactoferrin, green tea extract
Other · Dietary Supplement · Drug
Lead sponsor
Profact, Inc.
Other
Eligibility
20 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Tempe, Arizona
Completed Not applicable Interventional Accepts healthy volunteers Results available

Acute and Chronic Nicotine Modulation of Reinforcement Learning

NCT01830842
Conditions
Nicotine Addiction
Interventions
Nicotine polacrilex, Placebo, satiety, abstinence
Drug · Other
Lead sponsor
Duke University
Other
Eligibility
18 Years to 55 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Durham, North Carolina
Not listed Not applicable Interventional Accepts healthy volunteers

Probiotic Effect on Dietary Nitrate to Plasma Nitrite Production ( OPEDNPN )

NCT06375694
Conditions
Hypertension, Cardiovascular Diseases, Diabetes
Interventions
Herbiotics Oral + Ent Probiotic, Placebo
Dietary Supplement
Lead sponsor
Wake Forest University
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Conditions
Smoking, Smoking Cessation
Interventions
Nicotine lower dose, Nicotine higher dose, Placebo
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years and older
Enrollment
187 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
Burbank, California
Completed Phase 2 Interventional Accepts healthy volunteers Results available

A Pilot Study Evaluating Nicotine Lozenges and Self Help

NCT00888459
Conditions
Smokeless Tobacco Use
Interventions
nicotine replacement therapy, placebo NRT
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Male only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
2
States / cities
Rochester, Minnesota • Eugene, Oregon
Conditions
Epilepsy
Interventions
Progesterone Lozenges, Matched Placebo Lozenges
Biological · Other
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
13 Years to 45 Years · Female only
Enrollment
294 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2010
U.S. locations
14
States / cities
Los Angeles, California • Atlanta, Georgia • Baltimore, Maryland + 8 more
Conditions
Oral Health
Interventions
Oral probiotic, Placebo
Dietary Supplement
Lead sponsor
USANA Health Sciences
Industry
Eligibility
18 Years to 65 Years
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
South Jordan, Utah
Completed Not applicable Interventional Results available

Medicinal Nicotine for Preventing Cue Induced Craving

NCT02347605
Conditions
Tobacco Use Disorder
Interventions
Nicotine lozenge 4 mg, Placebo lozenge
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 64 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Acute Pharyngitis, Sore Throat
Interventions
flurbiprofen, placebo
Drug
Lead sponsor
Reckitt Benckiser LLC
Industry
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Storrs, Connecticut
Conditions
Argininosuccinate Lyase Deficiency, Urea Cycle Disorder, Urea Cycle Disorders, Inborn, Argininosuccinic Aciduria
Interventions
Neo-ASA, Placebo
Dietary Supplement
Lead sponsor
Baylor College of Medicine
Other
Eligibility
6 Years to 50 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Houston, Texas
Conditions
Oral Health
Interventions
PTx800 lozenges, Placebo control
Dietary Supplement
Lead sponsor
Primal Therapies Inc.
Industry
Eligibility
60 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Oral Leukoplakia
Interventions
Lozenge Intake
Drug
Lead sponsor
University of Medicine and Dentistry of New Jersey
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
1
States / cities
New Brunswick, New Jersey
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Genetically Informed Smoking Cessation Trial

NCT02351167
Conditions
Smoking Cessation
Interventions
Combination NRT (Nicotine patch, Nicotine lozenge), Varenicline, Placebo, Intensive smoking counseling
Drug · Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
21 Years and older
Enrollment
822 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Dental Caries
Interventions
xylitol, inactive lozenge
Dietary Supplement
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
25 Years to 80 Years
Enrollment
709 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
3
States / cities
Birmingham, Alabama • Chapel Hill, North Carolina • San Antonio, Texas
Completed Phase 2 Interventional Results available

Treatment of Oral Warts in HIV+ Patients

NCT00454181
Conditions
Papillomatosis, HIV Infections
Interventions
Interferon-alpha, placebo
Drug · Other
Lead sponsor
Ainos, Inc. (f/k/a Amarillo Biosciences Inc.
Industry
Eligibility
18 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
12
States / cities
San Francisco, California • Fort Lauderdale, Florida • Augusta, Georgia + 9 more
Completed Phase 1 Interventional Accepts healthy volunteers

Effect of Nicotine on Brain Reward Pathways

NCT02346539
Conditions
Depressive Disorder
Interventions
Nicotine polacrilex
Drug
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years to 45 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Belmont, Massachusetts
Completed Early Phase 1 Interventional Results available

Treatment of HFpEF With Nitrate Supplement

NCT03289481
Conditions
Heart Failure With Normal Ejection Fraction
Interventions
Active lozenge, Placebo
Dietary Supplement · Drug
Lead sponsor
MaineHealth
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Rockport, Maine
Conditions
Thyroiditis, Autoimmune
Interventions
Anatabloc Supplement, Placebo
Dietary Supplement
Lead sponsor
Rock Creek Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
165 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
9
States / cities
West Palm Beach, Florida • Zephyrhills, Florida • La Grange, Illinois + 5 more
Conditions
Oral Malodor
Interventions
Experimental lozenge with the enzyme Polyphenol oxidase and green coffee extract, Experimental lozenge with the enzyme Polyphenol oxidase, green coffee extract and flavor, Placebo lozenge control (sorbitol only), No product
Other
Lead sponsor
Novozymes A/S
Industry
Eligibility
18 Years and older
Enrollment
156 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Fort Wayne, Indiana
Conditions
Alzheimer Disease
Interventions
Anatabloc(R), Placebo
Dietary Supplement
Lead sponsor
Rock Creek Pharmaceuticals, Inc.
Industry
Eligibility
65 Years to 90 Years
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Sarasota, Florida
Conditions
Pharyngitis
Interventions
Placebo, Flurbiprofen
Drug
Lead sponsor
Reckitt Benckiser LLC
Industry
Eligibility
18 Years and older
Enrollment
204 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Storrs, Connecticut
Completed Phase 4 Interventional Results available

Stress Neuroadaptation in Tobacco Dependence

NCT03262233
Conditions
Nicotine Dependence
Interventions
nicotine, placebo
Combination Product · Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 60 Years
Enrollment
226 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Madison, Wisconsin