- Conditions
- Recurrent Urinary Tract Infection, Vaginal Atrophy, Postmenopausal Disorder
- Interventions
- Vaginal Cream with Applicator
- Drug
- Lead sponsor
- Jefferson Drapkin
- Other
- Eligibility
- 60 Years to 90 Years · Female only
- Enrollment
- 67 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2026
- U.S. locations
- 1
- States / cities
- Brooklyn, New York
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Showing 1–24
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matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Pelvic Floor Disorders
- Interventions
- Postmenopausal, topical vaginal estrogen cream, Placebo Comparator: Postmenopausal, topical placebo cream
- Drug
- Lead sponsor
- The University of Texas Medical Branch, Galveston
- Other
- Eligibility
- 21 Years to 70 Years · Female only
- Enrollment
- 7 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2023
- U.S. locations
- 1
- States / cities
- Galveston, Texas
- Conditions
- Microscopic Hematuria
- Interventions
- Premarin vaginal estrogen cream, Placebo vaginal cream
- Drug
- Lead sponsor
- Medstar Health Research Institute
- Other
- Eligibility
- Female only
- Enrollment
- 29 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 1
- States / cities
- Washington D.C., District of Columbia
- Conditions
- Female Sexual Dysfunction
- Interventions
- arginine 20%, nicotinamide .01%, niacin.1%, in LipodermPG 50%, Topical study cream, GRAS cream
- Drug
- Lead sponsor
- East Suburban Ob Gyn
- Other
- Eligibility
- 25 Years to 60 Years · Female only
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2010
- U.S. locations
- 1
- States / cities
- Monroeville, Pennsylvania
- Conditions
- Postoperative Bleeding, Gender Dysphoria, Hysterectomy
- Interventions
- Use of topical estradiol, No intervention
- Drug · Other
- Lead sponsor
- Women and Infants Hospital of Rhode Island
- Other
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 48 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Providence, Rhode Island
- Conditions
- Obstetric; Injury Pelvic Floor, Sexual Dysfunction, Anal Incontinence, Urinary Incontinence
- Interventions
- Estradiol 0.01% Vag Cream, Placebo vaginal cream
- Drug
- Lead sponsor
- University of Alabama at Birmingham
- Other
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 38 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2026
- U.S. locations
- 1
- States / cities
- Birmingham, Alabama
- Conditions
- Atrophic Vaginitis
- Interventions
- Estradiol Vaginal Cream, 0.01%, Estrace® 0.01% cream, Placebo Vaginal Cream
- Drug
- Lead sponsor
- Mylan Pharmaceuticals Inc
- Industry
- Eligibility
- 40 Years to 70 Years · Female only
- Enrollment
- 366 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2014
- U.S. locations
- 21
- States / cities
- Tucson, Arizona • Los Angeles, California • Sacramento, California + 16 more
- Conditions
- Infertility, Pregnancy
- Interventions
- Crinone vaginal progesterone gel, Placebo vaginal gel
- Drug
- Lead sponsor
- Wake Forest University Health Sciences
- Other
- Eligibility
- 18 Years to 40 Years · Female only
- Enrollment
- 20 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2008 – 2010
- U.S. locations
- 1
- States / cities
- Charlotte, North Carolina
- Conditions
- BACTERIAL VAGINOSIS, Signs and Symptoms to be Evaluated and Recorded Include, Vaginal Discharge Color, Odor, and Consistency, Vulvovaginal Itching and Irritation (Subjective) Absent, Mild, Moderate, or Severe, Vulvovaginal Inflammation (Objective) Absent, Mild, Moderate, or Severe
- Interventions
- clindamycin phosphate vaginal cream 2%, placebo
- Drug · Other
- Lead sponsor
- Actavis Inc.
- Industry
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 604 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014
- U.S. locations
- 15
- States / cities
- Birmingham, Alabama • La Mesa, California • San Diego, California + 12 more
- Conditions
- Vulvar and Vaginal Atrophy
- Interventions
- Estrace® Cream, Estradiol Vaginal Cream, Vehicle Cream
- Drug
- Lead sponsor
- Prasco LLC
- Industry
- Eligibility
- 30 Years to 75 Years · Female only
- Enrollment
- 540 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 27
- States / cities
- Sacramento, California • San Diego, California • Denver, Colorado + 23 more
- Conditions
- Long-Term Memory Decline, Mild Cognitive Impairment
- Interventions
- LabyrinthVR, Placebo Games, Coherence, Tablet
- Device
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 62 Years to 85 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2021
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Atrophy
- Interventions
- estrace cream (Perrigo), estrace cream (Reference), Placebo cream
- Drug
- Lead sponsor
- Padagis LLC
- Industry
- Eligibility
- 30 Years to 75 Years · Female only
- Enrollment
- 695 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016
- U.S. locations
- 1
- States / cities
- West Palm Beach, Florida
- Conditions
- Pelvic Organ Prolapse, Menopause
- Interventions
- Premarin, Placebo
- Drug · Other
- Lead sponsor
- University of Texas Southwestern Medical Center
- Other
- Eligibility
- 40 Years to 70 Years · Female only
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012 – 2013
- U.S. locations
- 1
- States / cities
- Dallas, Texas
- Conditions
- Pelvic Organ Prolapse
- Interventions
- Vaginal estrogen, Placebo
- Drug
- Lead sponsor
- Pamela Moalli
- Other
- Eligibility
- 40 Years to 80 Years · Female only
- Enrollment
- 21 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2023
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Overactive Bladder
- Interventions
- Toviaz, Premarin, Placebo cream
- Drug
- Lead sponsor
- The Cleveland Clinic
- Other
- Eligibility
- 30 Years to 100 Years · Female only
- Enrollment
- 90 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012 – 2018
- U.S. locations
- 1
- States / cities
- Weston, Florida
- Conditions
- HIV Prevention
- Interventions
- TFV 1% vaginal gel, HEC Placebo Gel
- Drug
- Lead sponsor
- CONRAD
- Other
- Eligibility
- 15 Years to 17 Years · Female only
- Healthy volunteers
- Accepts healthy volunteers
- U.S. locations
- 2
- States / cities
- The Bronx, New York • Salt Lake City, Utah
- Conditions
- Recurrent Urinary Tract Infection
- Interventions
- Conjugated Estrogen Vaginal Cream, Estradiol Ring, Placebo
- Drug
- Lead sponsor
- University of California, San Diego
- Other
- Eligibility
- 18 Years to 100 Years · Female only
- Enrollment
- 35 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2017
- U.S. locations
- 2
- States / cities
- La Jolla, California • New York, New York
- Conditions
- Stress Urinary Incontinence
- Interventions
- Vaginal ERT, Placebo
- Drug
- Lead sponsor
- University of California, Irvine
- Other
- Eligibility
- Female only
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2010
- U.S. locations
- 1
- States / cities
- Orange, California
- Conditions
- Atrophic Vaginitis
- Interventions
- Generic Estradiol Vaginal Cream USP, 0.01%, Estrace® Vaginal Cream USP, 0.01%, Vehicle Vaginal Cream
- Drug
- Lead sponsor
- Actavis Inc.
- Industry
- Eligibility
- 30 Years to 75 Years · Female only
- Enrollment
- 663 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2017
- U.S. locations
- 44
- States / cities
- Tucson, Arizona • La Mesa, California • Sacramento, California + 33 more
- Conditions
- Vaginal Health
- Interventions
- estriol, Placebo
- Drug
- Lead sponsor
- Gynuity Health Projects
- Other
- Eligibility
- 18 Years to 40 Years · Female only
- Enrollment
- 104 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2009 – 2011
- U.S. locations
- 2
- States / cities
- Los Angeles, California • Chicago, Illinois
- Conditions
- Menopause
- Interventions
- DR-2041a, DR-2041b, Placebo
- Drug · Other
- Lead sponsor
- Duramed Research
- Industry
- Eligibility
- 30 Years to 80 Years · Female only
- Enrollment
- 622 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2007
- U.S. locations
- 97
- States / cities
- Huntsville, Alabama • Mobile, Alabama • Montgomery, Alabama + 77 more
- Conditions
- Vestibulodynia, Temporomandibular Disorder, Fibromyalgia Syndrome, Irritable Bowel Syndrome, Migraines, Tension Headache, Endometriosis, Interstitial Cystitis, Back Pain, Chronic Fatigue Syndrome
- Interventions
- 5% lidocaine/5 mg/ml 0.02% estradiol compound cream, Nortriptyline, Placebo cream, Placebo pill
- Drug
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years to 50 Years · Female only
- Enrollment
- 209 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2024
- U.S. locations
- 2
- States / cities
- Los Angeles, California • Chapel Hill, North Carolina
- Conditions
- Vulvovaginal Candidiasis
- Interventions
- Butoconazole Nitrate Vaginal Cream, Placebo, Gynazole 1 vaginal cream
- Drug
- Lead sponsor
- Padagis LLC
- Industry
- Eligibility
- 18 Years to 75 Years · Female only
- Enrollment
- 611 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2008 – 2009
- U.S. locations
- 1
- States / cities
- Charlotte, North Carolina
- Conditions
- Atrophy of Vagina, Vaginal Ulceration, Vaginitis
- Interventions
- Estradiol, placebo
- Drug · Other
- Lead sponsor
- Northwell Health
- Other
- Eligibility
- 18 Years and older · Female only
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015
- U.S. locations
- 1
- States / cities
- Great Neck, New York