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ClinicalTrials.gov public records Last synced Oct 29, 2026, 4:26 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–21 of 21 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Placebo vaginal suppository Clear all

Conditions: Interstitial Cystitis, Bladder Pain Syndrome
Interventions: Cannabidiol vaginal suppository, Placebo vaginal suppository; Drug
Lead sponsor: University of New Mexico; Other
Eligibility: 18 Years and older · Female only
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Conditions: Pelvic Organ Prolapse, Stress Urinary Incontinence
Interventions: Lidocaine Hcl 2% Jelly, Placebo Jelly; Drug
Lead sponsor: University of South Florida; Other
Eligibility: 18 Years and older · Female only
Enrollment: 66 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Bacterial Vaginosis, Candidiasis, Trichomoniasis
Interventions: Neo-Penotran® Forte (active ingredient Metronidazole & Miconazole Nitrate), Placebo; Drug
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 234 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Pelvic Organ Prolapse
Interventions: Solifenacin, Placebo, Ring pessary with support, Cooper Surgical, Trumbell, CT Ref # MXPRS03 non-latex; Drug · Device
Lead sponsor: Hartford Hospital; Other
Eligibility: 18 Years and older · Female only
Enrollment: 94 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Hartford, Connecticut

Conditions: Vaginal Personal Care
Interventions: VM-02, Commercial Oral Probiotic Competitor, VM-02 Placebo; Other · Dietary Supplement
Lead sponsor: Seed Health; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 70 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Venice, California

Conditions: Stress Urinary Incontinence
Interventions: pessary, Absorbent pad; Device
Lead sponsor: Procter and Gamble; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 224 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Chandler, Arizona

Conditions: Vaginal Surgery
Interventions: Belladonna and Opium Suppositories, Placebo Suppositories; Drug
Lead sponsor: Kristina A. Butler; Other
Eligibility: 18 Years and older · Female only
Enrollment: 103 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Phoenix, Arizona

Conditions: Vaginal Atrophy
Interventions: Placebo, DHEA (0.25%), DHEA (0.5%), DHEA (1.0%); Drug
Lead sponsor: EndoCeutics Inc.; Industry
Eligibility: 40 Years to 75 Years · Female only
Enrollment: 218 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2008
U.S. locations: 2
States / cities: Cleveland, Ohio • Norfolk, Virginia

Conditions: Premenstrual Syndrome, Menstruation Disturbances
Interventions: Leuprolide, Estradiol Patches, Progesterone, Placebo patch, Placebo injection, Placebo suppository; Drug
Lead sponsor: National Institute of Mental Health (NIMH); NIH
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1992 – 2020
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Vaginal Atrophy
Interventions: Placebo, DHEA; Drug
Lead sponsor: EndoCeutics Inc.; Industry
Eligibility: 40 Years to 75 Years · Female only
Enrollment: 450 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 32
States / cities: Montgomery, Alabama • Tucson, Arizona • Little Rock, Arkansas + 27 more

Conditions: CIN 2/3, HPV Infection, Pre-Cancerous Dysplasia, Cervical Dysplasia, HPV Related Disease
Interventions: Artesunate vaginal insert, Placebo vaginal insert; Drug
Lead sponsor: Frantz Viral Therapeutics, LLC; Industry
Eligibility: 25 Years to 100 Years · Female only
Enrollment: 78 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2026
U.S. locations: 7
States / cities: Fort Myers, Florida • Ann Arbor, Michigan • Cleveland, Ohio + 2 more

Conditions: Pain
Interventions: lidocaine-prilocaine cream, Placebo cream; Drug
Lead sponsor: Loyola University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 54 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Maywood, Illinois

Conditions: Female Patients With High Tone Pelvic Floor Dysfunction
Interventions: Vaginal Diazepam Suppository, Placebo Suppository; Drug
Lead sponsor: TriHealth Inc.; Other
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Premature Birth, Obstetric Labor, Premature
Interventions: Micronized progesterone suppository; Drug
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 38 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2018
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Atrophy of Vagina, Vaginal Ulceration, Vaginitis
Interventions: Estradiol, placebo; Drug · Other
Lead sponsor: Northwell Health; Other
Eligibility: 18 Years and older · Female only
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015
U.S. locations: 1
States / cities: Great Neck, New York

Conditions: Abortion, Second Trimester
Interventions: Vaginal Misoprostol, Buccal Misoprostol; Drug
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 70 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Vaginal Personal Care
Interventions: VH-01 vaginal suppository tablet, Placebo vaginal suppository tablet; Other
Lead sponsor: Seed Health; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 1
States / cities: Santa Monica, California

Conditions: Office Hysteroscopy and Endometrial Biopsy
Interventions: Misoprostol 50 mcg pesssary, Placebos; Drug
Lead sponsor: University of South Florida; Other
Eligibility: 18 Years to 70 Years · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Short Cervical Length
Interventions: Vaginal progesterone, Placebo, Arabin Pessary; Drug · Device
Lead sponsor: The George Washington University Biostatistics Center; Other
Eligibility: Female only
Enrollment: 1,311 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2025
U.S. locations: 16
States / cities: Birmingham, Alabama • San Francisco, California • Denver, Colorado + 12 more

Conditions: Vaginal Atrophy
Interventions: Placebo, DHEA; Drug
Lead sponsor: EndoCeutics Inc.; Industry
Eligibility: 40 Years to 75 Years · Female only
Enrollment: 255 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 24
States / cities: Montgomery, Alabama • Tucson, Arizona • Sacramento, California + 20 more

Conditions: Chronic Pelvic Pain Syndrome
Interventions: 20 mg baclofen vaginal suppository daily per vagina, Placebo; Drug
Lead sponsor: University of Louisville; Other
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 39 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Louisville, Kentucky

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The CBD-IC Randomized Controlled Trial: Evaluation of Hemp Cannabidiol SuppositoRies for Pain and Urinary SymptOms in INterstitial Cystitis (CHRONIC)

Lidocaine for Pessary Check Pain Reduction

Topical Metronidazole and Miconazole Co-formulated Vaginal Suppositories for Preventing Vaginal Infections in HIV-seronegative Women

Clinical Trial of Solifenacin Versus Placebo Plus Pessary for Women With Vaginal Prolapse

Randomized, Double-blind, Placebo-controlled Trial Investigating the Role of a Personal Care Product on Vaginal Health

A Clinical Study to Assess the Safety of a Disposable Intra-vaginal Device for Stress Urinary Incontinence

Postoperative Belladonna and Morphine Suppositories in Vaginal Surgery

Topical DHEA Against Vaginal Atrophy

A Treatment Study for Premenstrual Syndrome (PMS)

Dehydroepiandrosterone (DHEA) Against Vaginal Atrophy

Artesunate Vaginal Inserts for the Treatment of Cervical Intraepithelial Neoplasia (CIN2/3)

Topical Anesthetic Use In Pessary Management

Diazepam Vaginal Suppositories for High Tone Pelvic Floor Dysfunction.

Vaginal Progesterone for the Prevention of Preterm Birth in Women With Arrested Preterm Labor

Vaginal Creams to Reduce Vaginal Erosion in Pessary Users

24-hour Mifepristone and Buccal Versus Mifepristone and Vaginal Misoprostol for Cervical Preparation for D&E

Randomized, Double-Blind Placebo-Controlled Trial to Assess Overall User Experience of a Synbiotic Vaginal Suppository

Misoprostol in Office Hysteroscopy and Endometrial Biopsy

A Trial of Pessary and Progesterone for Preterm Prevention in Twin Gestation With a Short Cervix

DHEA Against Vaginal Atrophy - 3-Month Efficacy Study

Vaginal Baclofen Suppositories in Chronic Pelvic Pain