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Conditions: Venous Leg Ulcer, Venous Leg, Diabetic Foot, Diabetic Foot Ulcer, Foot Ulcer, Diabetic, Ulcer Foot, Leg Ulcer, Ulcer Venous, Ulcer
Interventions: ACApatch™, caregraFT™, Standard of Care; Other
Lead sponsor: Tiger Biosciences, LLC.; Industry
Eligibility: 21 Years and older
Enrollment: 340 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Monroeville, Pennsylvania

Conditions: Wounds
Interventions: blood draw; Procedure
Lead sponsor: The University of Texas Medical Branch, Galveston; Other
Eligibility: 16 Years to 65 Years · Female only
Enrollment: 1,164 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 1999 – 2014
U.S. locations: 1
States / cities: Galveston, Texas

Conditions: Diabetic Foot Ulcer
Interventions: AMNIOEXCEL Plus Amniotic Membrane, A Marketed Comparator, Standard of Care; Other · Device
Lead sponsor: Integra LifeSciences Corporation; Industry
Eligibility: 21 Years and older
Enrollment: 116 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 7
States / cities: Fresno, California • Los Angeles, California • Gainesville, Georgia + 3 more

Conditions: Vascular Diseases
Interventions: Vialize; Other
Lead sponsor: University of Florida; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Diabetic Foot, Lower Extremity Wound
Interventions: Matrion, Conventional Care Wound Management; Other
Lead sponsor: LifeNet Health; Industry
Eligibility: 21 Years to 80 Years
Enrollment: 108 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 8
States / cities: Tucson, Arizona • Carmichael, California • Fresno, California + 5 more

Conditions: Diabetic Foot Ulcer, Venous Leg Ulcer
Interventions: Amnion-Intermediate-Chorion, Amnion-Chorion-Amnion, Standard of Care; Other · Procedure
Lead sponsor: Cellution Biologics; Industry
Eligibility: 18 Years to 98 Years
Enrollment: 292 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 4
States / cities: Jacksonville, Florida • Cincinnati, Ohio • Weslaco, Texas + 1 more

Conditions: Pain, Postoperative, Gingival Diseases
Interventions: amnion-chorion membrane, Sutures; Device · Procedure
Lead sponsor: Harvard Medical School (HMS and HSDM); Other
Eligibility: 18 Years to 85 Years
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Pathologic Processes, Diabetes Mellitus, Glucose Metabolism Disorders, Metabolic Diseases, Endocrine System Disease, Diabetic Angiopathies, Vascular Diseases, Cardiovascular Diseases, Leg Ulcer, Skin Ulcer, Skin Diseases, Diabetes Complications, Diabetic Neuropathies, Foot Diseases, Diabetic Foot, Foot Ulcer, Diabetes Mellitus, Type 2, Ulcer, Foot Ulcer Unhealed
Interventions: Standard of Care - DFU, AM/Single - DFU, AM/Double - DFU, Standard of Care - VLU, AM/Single - VLU, AM/Double - VLU; Other
Lead sponsor: C5 Biomedical; Industry
Eligibility: 18 Years and older
Enrollment: 177 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Metairie, Louisiana

Conditions: Chronic Wounds, Diabetic Ulcers
Interventions: Not listed
Lead sponsor: StimLabs; Industry
Eligibility: 18 Years and older
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 3
States / cities: Oklahoma City, Oklahoma • Denison, Texas • Frisco, Texas

Conditions: Protruded Disk
Interventions: CLARIX™100, CLARIX CORD 1K; Other
Lead sponsor: Amniox Medical, Inc.; Industry
Eligibility: 18 Years to 90 Years
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2020
U.S. locations: 1
States / cities: Bensalem, Pennsylvania

Conditions: Diabetic Foot Ulcer, Foot Ulcer Chronic, DFU, Ulcer Foot, Venous Leg Ulcer (VLU), Venous Leg Ulcer, Venous Ulcer, Leg Ulcers, Ulcer
Interventions: Tri-Membrane Wrap™ DFU, Membrane Wrap™ DFU, Membrane Wrap-Lite™ DFU, Membrane Wrap-Hydro™ DFU, Tri-Membrane Wrap™ VLU, Membrane Wrap™ VLU, Membrane Wrap-Lite™ VLU, Membrane Wrap-Hydro™ VLU; Other
Lead sponsor: BioLab Holdings; Industry
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Philidelphia, Pennsylvania

Conditions: Diabetic Foot Ulcer
Interventions: Standard of Care, NeoThelium FT; Other
Lead sponsor: NuScience Medical Biologics, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 132 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 8
States / cities: Alexandria, Louisiana • Franklinton, Louisiana • Hammond, Louisiana + 5 more

Conditions: COVID19
Interventions: Biospecimen collection; Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 69 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Achilles Tendinopathy
Interventions: Flo, Saline; Other
Lead sponsor: North Park Podiatry; Other
Eligibility: 18 Years to 64 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: San Diego, California

Conditions: Diabetic Foot Ulcer (DFU), Venous Leg Ulcer (VLU)
Interventions: DermaBind TL; Biological
Lead sponsor: HealthTech Wound Care; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 10
States / cities: DeLand, Florida • Palm Beach Gardens, Florida • Sweetwater, Florida + 7 more

Conditions: Diabetic Foot Ulcer
Interventions: NeoThelium FT (HCT/P 361); Other
Lead sponsor: NuScience Medical Biologics, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 3
States / cities: Alexandria, Louisiana • Leesville, Louisiana • Many, Louisiana

Conditions: Pressure Injury
Interventions: NeoThelium FT (HCT/P 361); Other
Lead sponsor: NuScience Medical Biologics, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 2
States / cities: Bossier City, Louisiana • Rayville, Louisiana

Conditions: Foot Ulcer, Diabetic
Interventions: NEOX® CORD 1K, Standard of Care (Pressure Bandage); Other · Procedure
Lead sponsor: Amniox Medical, Inc.; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 3
States / cities: Tucson, Arizona • Castro Valley, California • Newnan, Georgia

Conditions: Preterm Labor, Preterm Birth
Interventions: PAMG-1 immunoassay; Device
Lead sponsor: Mark Santillan; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 162 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Diabetic Foot Ulcer, Diabetic Foot, Foot Ulcer Due to Type 2 Diabetes Mellitus, Foot Ulcer, Diabetic, Foot Ulcer
Interventions: Standard of Care, EPIEFFECT, EPIXPRESS; Other
Lead sponsor: MiMedx Group, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 170 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Monroeville, Pennsylvania

Conditions: Horizontal Ridge Deficiency
Interventions: Guided bone regeneration (GBR); Procedure
Lead sponsor: University of Michigan; Other
Eligibility: 21 Years and older
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Diabetic Foot Ulcer, Diabetic Foot, Foot Ulcer, Ulcer Foot, DFU
Interventions: SLAM + SOC, SOC; Other
Lead sponsor: Applied Biologics, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 124 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Clinton Township, Michigan

Conditions: Lower Extremity Chronic Ulcers in Diabetics, Diabetic Foot Ulcer (DFU)
Interventions: amniotic membrane; Other
Lead sponsor: Tides Medical; Industry
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023
U.S. locations: 5
States / cities: North Port, Florida • Buffalo, New York • Monroeville, Pennsylvania + 2 more

Conditions: Hidradenitis Suppurativa
Interventions: AMP-001 Low Dose, AMP-001 Medium Dose, AMP-001 High Dose; Drug
Lead sponsor: IntegoGen, LLC; Industry
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: Houston, Texas

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Evaluating Several Cellular, Acellular, and Matrix-like Products (CAMPs) and Standard of Care Versus Standard of Care Alone in the Management of Nonhealing Diabetic Foot and Venous Leg Ulcers.

Study of Donated Amnion, Fetal Placental Membrane, as Skin Substitute for Burn Patients

AMNIOEXCEL® Plus vs A Marketed Comparator vs SOC in the Management of Diabetic Foot Ulcers

Vialize Use for the Reduction of Vascular Groin Incisional Dehiscence and Infection

Matrion™ Decellularized Placental Membrane in Subjects With Diabetic Foot Ulcers

Study Evaluating Several CAMPs in Nonhealing Diabetic Foot and Venous Leg Ulcers

Effect of Using Placental Membranes on Healing and Post-op Pain After Gum Surgery

Clinical Trial Assessing Human Placental Membrane Products and Standard of Care Versus Standard of Care in Nonhealing DFUs and VLUs

Real-world Study of StimLabs Human Placental Membrane Tissue to Treat Hard-to-Heal Wounds

CLARIX™ 100 & CLARIX CORD 1K for Discectomy Patients

A Multicenter, Prospective, Controlled Modified Multi-Platform Trial Assessing the Efficacy of Human Placental Membrane Products and Standard of Care in the Management of Nonhealing Diabetic Foot Ulcers and Venous Leg Ulcers.

Evaluating the Efficacy NeoThelium FT in the Treatment of Diabetic Foot Ulcers

Risks of COVID19 in the Pregnant Population

AM for Refractory Achilles Tendinopathy

A Non-Randomized Open Label Clinical Trial Evaluating DermaBind TL

Prospective Case Series Evaluating the Efficacy and Safety of NeoThelium FT for Diabetic Foot Ulcers

Prospective Case Series Evaluating the Efficacy and Safety of NeoThelium FT for Chronic Pressure Ulcers

NEOX® CORD 1K vs Standard of Care in Non-healing Diabetic Foot Ulcers

Use of Placental Alpha Microglobulin-1(PAMG-1) to Diagnose Premature Rupture of Membranes in Pregnant Women

Modified Platform Trial Evaluating PpLHACM and SOC Versus SOC Alone in the Treatment of Nonhealing DFUs

The "Open Wound Bone Augmentation Concept" with Amnion-Chorion Membrane

Evaluating the Efficacy of a Single Layer Placental-based Allograft and Standard of Care Versus Standard of Care

Artacent Amniotic Tissue for Treatment of Chronic Lower Extremity Diabetic Ulcers.

Allogeneic Micronized Amniotic Membrane Product for the Treatment of Hidradenitis Suppurativa