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Conditions: Psychotic Disorders, Prodromal Symptoms, Prodromal Schizophrenia, Psychosis, Family
Interventions: Family Focused Therapy for Clinical High Risk Youth (FFT-CHR), Enhanced Care (EC); Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 13 Years to 25 Years
Enrollment: 220 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 6
States / cities: Los Angeles, California • San Diego, California • San Francisco, California + 3 more

Conditions: Cancer, Pain, Pain Management, Chronic Pain, American Indian or Alaska Native
Interventions: Empowered Relief; Behavioral
Lead sponsor: University of Oklahoma; Other
Eligibility: 18 Years and older
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Tulsa, Oklahoma

Conditions: Bone Metastases
Interventions: Radiation Therapy; Drug
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 220 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Child Abuse
Interventions: Healthy Families Durham, Yearly Checkup; Behavioral
Lead sponsor: Duke University; Other
Eligibility: Female only
Enrollment: 343 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2011
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Chemotherapeutic Agent Toxicity, Neuropathy, Neurotoxicity Syndrome, Pain, Stage IIIA Fallopian Tube Cancer, Stage IIIA Ovarian Cancer, Stage IIIA Primary Peritoneal Cancer, Stage IIIB Fallopian Tube Cancer, Stage IIIB Ovarian Cancer, Stage IIIB Primary Peritoneal Cancer, Stage IIIC Fallopian Tube Cancer, Stage IIIC Ovarian Cancer, Stage IIIC Primary Peritoneal Cancer, Stage IV Fallopian Tube Cancer, Stage IV Ovarian Cancer, Stage IV Primary Peritoneal Cancer
Interventions: Carboplatin, Glutathione, Laboratory Biomarker Analysis, Paclitaxel, Placebo, Quality-of-Life Assessment; Drug · Other
Lead sponsor: Alliance for Clinical Trials in Oncology; Other
Eligibility: 18 Years and older
Enrollment: 195 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 390
States / cities: Mobile, Alabama • Fairbanks, Alaska • Scottsdale, Arizona + 259 more

Conditions: Clinical Trial
Interventions: Family Check-Up 4 Health, Services as Usual; Behavioral · Other
Lead sponsor: Arizona State University; Other
Eligibility: 2 Years to 5 Years
Enrollment: 217 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2024
U.S. locations: 4
States / cities: Avondale, Arizona • Tempe, Arizona

Conditions: Sarcoma
Interventions: epirubicin hydrochloride, ifosfamide, sorafenib tosylate, immunoenzyme technique, immunohistochemistry staining method, laboratory biomarker analysis, adjuvant therapy, neoadjuvant therapy, therapeutic conventional surgery, hypofractionated radiation therapy; Drug · Other · Procedure + 1 more
Lead sponsor: OHSU Knight Cancer Institute; Other
Eligibility: 15 Years to 120 Years
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Lung Cancer, Esophageal Cancer
Interventions: Carboplatin, Paclitaxel, Radiation Therapy; Drug · Radiation
Lead sponsor: Fox Chase Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Human Papillomavirus Vaccination
Interventions: Counseling; Behavioral
Lead sponsor: Plan A Health, Inc; Other
Eligibility: 18 Years to 35 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Louise, Mississippi

Conditions: Colorectal Cancer
Interventions: Motivational interview, Standard of care; Behavioral
Lead sponsor: University of Kentucky; Other
Eligibility: 50 Years and older
Enrollment: 191 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: Morehead, Kentucky

Conditions: Parent-child Interaction
Interventions: PFR Group, Resource & Referral Group; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: Not listed
Enrollment: 225 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2021
U.S. locations: 1
States / cities: Eagle Butte, South Dakota

Conditions: Carotid Artery Disease, Carotid Stenosis
Interventions: [F-18] RDG-K5; Drug
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years and older
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Breast Cancer
Interventions: Lumpectomy without sentinel node biopsy; Procedure
Lead sponsor: Cedars-Sinai Medical Center; Other
Eligibility: 18 Years and older · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Intensive Care Unit Days
Interventions: Proactive Ethics Intervention; Behavioral
Lead sponsor: California Pacific Medical Center Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 386 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Tibial Shaft Fracture, Tibial Plateau Fracture
Interventions: Acute injury without compartment syndrome, Acute injury with compartment syndrome, Exertional compartment syndrome; Procedure
Lead sponsor: University of Utah; Other
Eligibility: 18 Years to 90 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2028
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Suicidal Ideation, Suicide Attempt, Safety Plan, Depression / Major Depressive Disorder, Hopelessness
Interventions: CAMS Brief Intervention, Stanley-Brown Safety Planning Intervention; Behavioral
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 12 Years to 17 Years
Enrollment: 118 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: COVID-19
Interventions: RT-PCR Test, Real-time PCR Test; Diagnostic Test
Lead sponsor: QuantuMDx Group Ltd; Industry
Eligibility: 18 Years and older
Enrollment: 877 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 3
States / cities: Miami, Florida • Knoxville, Tennessee • Memphis, Tennessee

Conditions: Psychosis, Schizophrenia, Schizoaffective Disorder, Psychosis Nos/Other, Bipolar Disorder
Interventions: Care Coordination, Individual Peer Support, Digital Outreach, Cognitive Remediation, Multi-Family Group Therapy; Behavioral
Lead sponsor: Mclean Hospital; Other
Eligibility: Not listed
Enrollment: 350 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 5
States / cities: Belmont, Massachusetts • Boston, Massachusetts • Cambridge, Massachusetts + 1 more

Conditions: Type 2 Diabetes
Interventions: GSH Foods, Nutrition education about glutathione sources in the diet, Standard of care nutrition education for type 2 diabetes; Other
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years to 65 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: San Diego, California

Conditions: Cardiovascular Diseases, Type 2 Diabetes Mellitus in Obese, Hyperlipidemias
Interventions: CHAI dyad study; Behavioral
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 20 Years to 70 Years
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: New Brunswick, New Jersey

Conditions: Hypertension
Interventions: Lifestyle Immersion Intervention that will address Nutrition, Physical Fitness, and BP Self-Monitoring3 Elements:; Behavioral
Lead sponsor: Meharry Medical College; Other
Eligibility: 30 Years to 80 Years
Enrollment: 220 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Multiple Sclerosis, Balance, Fatigue, Eye Movement
Interventions: Vestibular rehabilitation: balance and eye movement exercises; Other
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years to 60 Years
Enrollment: 88 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2018
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Suicide and Self-harm, Suicide, Suicide, Attempted, Suicidal Ideation
Interventions: Mobile Application to Prevent Suicide (MAPS); Behavioral
Lead sponsor: Butler Hospital; Other
Eligibility: 18 Years to 70 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 2
States / cities: Providence, Rhode Island

Conditions: Posterior Cortical Atrophy
Interventions: HD-tDCS sessions, Sham HD-tDCS sessions, HD-tDCS sessions - Open-label (after randomized treatment); Device
Lead sponsor: University of Michigan; Other
Eligibility: 50 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Ann Arbor, Michigan

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Family-Focused Therapy for Individuals at High Clinical Risk for Psychosis: A Confirmatory Efficacy Trial

Feasibility and Acceptability of Empowered Relief for American Indians With Pain During and After Cancer Treatment

A Phase III Randomized Trial Comparing Stereotactic Body Radiation Therapy (SBRT) vs Conventional Palliative Radiation Therapy for Painful Bone Metastases

Evaluation of a Home Visiting Program for First Time Parents

Glutathione in Preventing Peripheral Neuropathy Caused by Paclitaxel and Carboplatin in Patients With Ovarian Cancer, Fallopian Tube Cancer, and/or Primary Peritoneal Cancer

AFRI Childhood Obesity Prevention Challenge Area

Sorafenib, Epirubicin, Ifosfamide, and Radiation Therapy Followed By Surgery in Treating Patients With High-Risk Stage II or Stage III Soft Tissue Sarcoma

Observation Study of Patients With Non-Small Cell Lung Cancer and Esophageal Cancer Treated With Chemo-Radiation Followed by Surgery

Investigating HPV Vaccination Uptake in Adults Aged 18-35 Seeking Care at a Health Clinic in Rural Mississippi

Promoting Colorectal Cancer Screening in Rural Emergency Departments

A Primary Prevention Trial to Strengthen Child Attachment in a Native Community

TRACER RGD-K5 Carotid Plaque Imaging Study

Safety and Efficacy of Sentinel Node Biopsy Omission for Breast Cancer Patients Who Plan to Have Adjuvant Chemotherapy

Proactive Ethics Intervention to Improve Intensive Care Unit (ICU) Care

Gene Expression in Lower Extremity Acute Traumatic Compartment Syndrome

Youth Suicide Prevention: CAMS-BI vs. Safety Planning in a Randomized Trial

Q-POC SARS-CoV-2 Assay COVID-19 Clinical Evaluation

Enhanced Coordinated Specialty Care for Early Psychosis

Glutathione-rich Foods for Type 2 Diabetes

Implementation of a Peer Leader-facilitated Dyadic Intervention

Team Lifestyle Immersion Hypertension Control Project

Vestibular Rehabilitation for Persons With Multiple Sclerosis: Who Benefits the Most? (MSVR3trial)

Examining Feasibility, Acceptability, and Sustainability of a Novel Personalized Smartphone Intervention for Suicide - Open Trial

Testing Personalized High-Definition Transcranial Direct Current Stimulation (HD-tDCS) as a Treatment of Posterior Cortical Atrophy