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Showing 1–24 of 28 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Plantar flexion Clear all
Recruiting Phase 1Phase 2 Interventional

Hybrid Robot+FES Stroke Rehabilitation

NCT04550728
View directory record Official record
Conditions
Stroke
Interventions
Ankle robot training group, Ankle robot training and functional electrical stimulation(FES) group
Combination Product
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Sep 3, 2026, 1:37 PM EDT
Completed Not applicable Interventional

The Effects of Plantar Flexion Training in People With Chronic Stroke

NCT03548090
View directory record Official record
Conditions
Stroke, Hemiplegic Gait
Interventions
Skateboard exercise at an incline angle of 0 degrees and 50% body weight, Skateboard exercise at an incline angle of 5 degrees and 50% body weight, Skateboard exercise at an incline angle determined to be optimal in phase 1 (either 0 or 5 degrees) and 75% body weight, Skateboard exercise at an incline angle determined to be optimal in phase 1 (either 0 or 5 degrees) and 90% body weight, Control 4-week exercise intervention, Experimental 4-week exercise intervention, Over-ground multi-directional gait training, Home exercise
Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 30, 2021 · Synced Sep 3, 2026, 1:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Does the Addition of Manual Therapy Techniques Increase Gastrocnemius/Soleus Length More Than Stretching Alone?

NCT01856972
View directory record Official record
Conditions
Muscle Tightness
Interventions
Instrument Assisted Soft Tissue Mobilization, Rearfoot joint mobilization, Static stretching/ROM exercises
Procedure · Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
12 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 10, 2014 · Synced Sep 3, 2026, 1:37 PM EDT
Not listed Not applicable Interventional

Effects of Osteopathic Manipulative Treatment (OMT) on Gait Biomechanics in Parkinson's Disease

NCT03616145
View directory record Official record
Conditions
Parkinson Disease
Interventions
Osteopathic Manipulative Treatment (OMT), Light Touch
Procedure · Other
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Nov 12, 2023 · Synced Sep 3, 2026, 1:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Medial Tibial Stress Syndrome Prevention

NCT07256808
View directory record Official record
Conditions
Medial Tibial Stress Syndrome
Interventions
Resistance Training
Other
Lead sponsor
Rowan University
Other
Eligibility
18 Years to 65 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Glassboro, New Jersey
Source: ClinicalTrials.gov public record
Updated Nov 30, 2025 · Synced Sep 3, 2026, 1:37 PM EDT
Terminated Not applicable Interventional

Condensed Percutaneous Tibial Nerve Stimulation (PTNS) Protocol

NCT03559946
View directory record Official record
Conditions
Overactive Bladder Syndrome
Interventions
percutaneous tibial nerve stimulation (PTNS), Sham procedure
Device
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Aug 13, 2023 · Synced Sep 3, 2026, 1:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Exercise Versus Exercise and Instrument-Assisted Soft Tissue Mobilization for Plantar Fasciopathy Treatment

NCT04162262
View directory record Official record
Conditions
Plantar Fascitis
Interventions
Instrumental-assisted soft tissue mobilization (IASTM), High-Load Strength Training, Plantar Flexor and Gastrocnemius Stretching
Other
Lead sponsor
Texas Tech University Health Sciences Center
Other
Eligibility
18 Years to 60 Years
Enrollment
83 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Feb 4, 2021 · Synced Sep 3, 2026, 1:37 PM EDT
Not yet recruiting Not applicable Interventional

Understanding the Effects of Pulmonary Arterial Hypertension on Lean Muscle Mass-Substudy

NCT07781709
View directory record Official record
Conditions
Pulmonary Arterial Hypertension
Interventions
Measurement of oxyhemoglobin and deoxyhemoglobin concentration pre and post- exercise at baseline and Week 12. Measurement of time to recovery of oxyhemglobin post-exercise at baseline and at Week 12., Blood draw
Device · Diagnostic Test
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Sep 3, 2026, 1:37 PM EDT
Recruiting Phase 2 Interventional

Passive Stretching in Peripheral Arterial Disease Patients

NCT06420752
View directory record Official record
Conditions
Peripheral Arterial Disease, Walking, Difficulty, Inflammation
Interventions
Calf Plantar flexion, Dietary nitrate
Device · Dietary Supplement
Lead sponsor
University of Wisconsin, La Crosse
Other
Eligibility
40 Years to 90 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
La Crosse, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 1, 2025 · Synced Sep 3, 2026, 1:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Biomechanical Assessment of Gait in Lower-Extremity-Amputees

NCT01332123
View directory record Official record
Conditions
Prosthesis User
Interventions
Alignment perturbations
Device
Lead sponsor
University of Wisconsin, Milwaukee
Other
Eligibility
18 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 8, 2016 · Synced Sep 3, 2026, 1:37 PM EDT
Terminated Not applicable Interventional Results available

Yoga to Alleviate Fatigue, Anxiety and Pain in Adolescents During Treatment for Lymphoma or Leukemia

NCT02473523
View directory record Official record
Conditions
Leukemia, Hodgkin Lymphoma, Lymphoma, Non-Hodgkin's
Interventions
PedsQL Cancer Module, PedsQL Multidimensional Fatigue Scale, Biodex System 3 Dynamometer, Jamar Hydraulic Hand Dynamometer, Sit and Reach Test, Test of Motor Proficiency, Verbal Numeric Pain Scale, :Yoga Therapy
Other · Device
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
13 Years to 17 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 7, 2017 · Synced Sep 3, 2026, 1:37 PM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

: Vascular Function in Health and Disease

NCT02966665
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease, Pulmonary Artery Hypertension, Heart Failure, Hypertension
Interventions
Maximum Exercise Tests, BH4, L-NMMA, Vitamin C, Vitamin E, α-Lipoic Acid and L-Ascorbate, BQ-123, Fexofenadine, Ranitidine, Angiotensin-II, Valsartan, Acetylcholine, Sodium Nitroprusside, Angiotensin-II, Norepinephrine, Phentolamine, BQ-123, MitoQ, BH4
Other · Drug
Lead sponsor
Russell Richardson
Other
Eligibility
18 Years and older
Enrollment
420 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2026
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Sep 25, 2025 · Synced Sep 3, 2026, 1:37 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Ultrasound Perfusion Estimation for Assessment of Peripheral Arterial Disease

NCT06952543
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Ultrasound Imaging
Diagnostic Test
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Sep 3, 2026, 1:37 PM EDT
Not listed Not applicable Interventional

CAN-Stim Compared to SNS in Treatment of Urinary Urgency Incontinence With Wireless Neuromodulation Technology

NCT02577302
View directory record Official record
Conditions
Urinary Incontinence, Urge
Interventions
CAN-Stim - Protect CAN-Stim System, SNS - InterStim® System
Device
Lead sponsor
Uro Medical Corporation
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
15
States / cities
Laguna Hills, California • Los Angeles, California • Orange, California + 12 more
Source: ClinicalTrials.gov public record
Updated Oct 3, 2023 · Synced Sep 3, 2026, 1:37 PM EDT
Terminated Not applicable Interventional

INvestigation of TENS Efficacy Versus Posterior Tibial Nerve Stimulation for Overactive Bladder

NCT05309993
View directory record Official record
Conditions
Overactive Bladder, Overactive Bladder Syndrome, Urinary Urge Incontinence, Urinary Bladder, Overactive, Urinary Incontinence, Urge
Interventions
PTNS, TENS
Device
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years and older · Female only
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Oct 30, 2025 · Synced Sep 3, 2026, 1:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Change in MUNIX in Patients With CMT1A Undergoing a Home Ankle Strengthening Program Versus Standard of Care

NCT03715283
View directory record Official record
Conditions
Charcot-Marie-Tooth Disease
Interventions
Home Ankle Strengthing Program, Standard of Care
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 19, 2019 · Synced Sep 3, 2026, 1:37 PM EDT
Not listed Not applicable Interventional

Effects Of Osteopathic Manipulative Medicine(OMM) On Lower Extremity Muscle Characteristics In Parkinson's Disease(PD) Patients

NCT05884944
View directory record Official record
Conditions
Parkinson Disease, Osteopathy in Diseases Classified Elsewhere
Interventions
Sham- Light touch, not reaching restrictive barrier, Experimental: Interventional Group- OMM- Muscle energy
Procedure
Lead sponsor
New York Institute of Technology
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Aug 6, 2024 · Synced Sep 3, 2026, 1:37 PM EDT
Terminated Phase 2 Interventional Results available

Ferric Carboxymaltose to Improve Skeletal Muscle Metabolism in Heart Failure Patients With Functional Iron Deficiency

NCT03218384
View directory record Official record
Conditions
Iron-deficiency
Interventions
Ferric Carboxymaltose, Placebo, 31P MRS/MRI
Drug · Device
Lead sponsor
NYU Langone Health
Other
Eligibility
21 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 4, 2023 · Synced Sep 3, 2026, 1:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Physiologic Range of Step-by-step Variations in Lower Limb Prosthesis Forces During Walking

NCT02234505
View directory record Official record
Conditions
Trans-tibial Limb Loss
Interventions
Prosthetic alignment perturbation
Procedure
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 3, 2015 · Synced Sep 3, 2026, 1:37 PM EDT
Completed Not applicable Interventional Results available

Can Transcranial Direct Current Stimulation Improve Ambulation and Fatigue Resistance in People With MS?

NCT02987621
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
tDCS
Device
Lead sponsor
Colorado State University
Other
Eligibility
30 Years to 60 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 29, 2020 · Synced Sep 3, 2026, 1:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Trial of Tibial Nerve Stimulation for Treating Sexual Dysfunction

NCT04122703
View directory record Official record
Conditions
Female Sexual Dysfunction
Interventions
percutaneous tibial nerve stimulation (PTNS), Sham procedure
Device
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older · Female only
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Sep 3, 2026, 1:37 PM EDT
Completed Not applicable Interventional Results available

The General Use of Robots in Stroke Recovery: the Anklebot

NCT02249832
View directory record Official record
Conditions
Stroke
Interventions
seated robot-assisted ankle therapy
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
2
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Mar 8, 2021 · Synced Sep 3, 2026, 1:37 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Targeting Oxidative Stress to Prevent Vascular and Skeletal Muscle Dysfunction During Disuse

NCT04351113
View directory record Official record
Conditions
Aging, Oxidative Stress, Vascular Endothelium, Skeletal Muscle, Antioxidants
Interventions
MITO-AO, PB-125, Placebo, Passive Leg Movement (PLM), Plantar flexion, Isometric knee extensor test, Bed rest
Dietary Supplement · Other
Lead sponsor
Joel Trinity
Other
Eligibility
65 Years to 85 Years
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Sep 3, 2026, 1:37 PM EDT
Active, not recruiting Not applicable Interventional

Impact of Powered Knee-Ankle Prosthesis Leg on Everyday Community Mobility and Social Interaction

NCT03204513
View directory record Official record
Conditions
Transfemoral Amputees
Interventions
Vanderbilt Powered Knee-Ankle Prosthesis, Microprocessor (MP) Knee Prosthesis
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 80 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Sep 3, 2026, 1:37 PM EDT