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ClinicalTrials.gov public records Last synced Sep 7, 2026, 11:34 AM EDT

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Showing 1–17 of 17 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Polydioxanone Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

Affixing Polypropylene Mesh Using Barbed Suture (Quill™ SRS) During Robotic Assisted Laparoscopic Sacrocolpopexy

NCT01608568
View directory record Official record
Conditions
Prolapse
Interventions
Device is the type of suture used: Quill suture vs. Interrupted suture
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older · Female only
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated May 31, 2012 · Synced Sep 7, 2026, 11:34 AM EDT
Not yet recruiting Not applicable Interventional

Antibiotic-coated Braided Suture Study

NCT07322289
View directory record Official record
Conditions
Prosthetic Joint Infection, Debridement With Prosthesis Retention, Prosthetic Joint Infections of Hip, Prosthetic Joint Infections of Knee, Suture
Interventions
VICRYL™ Plus (Coated VICRYL™ Plus Antibacterial), Polydioxanone (PDS™ II ) Sterile Synthetic Absorbable Surgical Suture-Monofilament
Device
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 89 Years
Enrollment
142 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Sep 7, 2026, 11:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Affixing Polypropylene Mesh Using Barbed Suture (Quill™ Srs) During Laparoscopic Sacrocolpopexy Randomized Controlled Trial (Quill Lsc)

NCT01551992
View directory record Official record
Conditions
Prolapse
Interventions
Quill suture vs. Interrupted suture
Procedure
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older · Female only
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 15, 2014 · Synced Sep 7, 2026, 11:34 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Shear-Wave Elastography

NCT06306976
View directory record Official record
Conditions
Ventral Incisional Hernia
Interventions
Elective Midline Laparotomy, Imaging: Ultrasound, Tensiometry
Procedure · Other
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Sep 7, 2026, 11:34 AM EDT
Completed Not applicable Interventional Results available

Permanent Versus Absorbable Colpopexy Trial

NCT02277925
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Polytetrafluoroethylene, Polydioxanone
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older · Female only
Enrollment
204 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
5
States / cities
Augusta, Georgia • Chicago, Illinois • Chapel Hill, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 18, 2019 · Synced Sep 7, 2026, 11:34 AM EDT
Completed Not applicable Interventional

EFS of Bioabsorbable Implant for NSD

NCT05967169
View directory record Official record
Conditions
Nasal Septal Deviation
Interventions
Nasal Septal Strap implantation
Device
Lead sponsor
Spirair, Inc
Industry
Eligibility
21 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
Torrance, California • Bethlehem, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Sep 7, 2026, 11:34 AM EDT
Completed Not applicable Interventional Results available

Negative Pressure Wound Therapy in Obese Gynecologic Oncology Patients

NCT02309944
View directory record Official record
Conditions
Postoperative Complications, Obesity, Gynecologic Neoplasms
Interventions
Standard Wound Closure, Prevena™ Incision Management System
Procedure · Device
Lead sponsor
Masonic Cancer Center, University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 26, 2020 · Synced Sep 7, 2026, 11:34 AM EDT
Completed Not applicable Interventional Results available

Barbed Suture Versus Non-Barbed Suture for Posterior Colporrhaphy

NCT04658784
View directory record Official record
Conditions
Rectocele
Interventions
2-0 dioxanone, glycolide and trimethylene carbonate, 2-0 polydioxanone
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older · Female only
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated May 5, 2023 · Synced Sep 7, 2026, 11:34 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Ostomy Primary Closure With 0.1% Betaine/Polyhexanide Wound Irrigation Compared to Pursestring Closure

NCT06309368
View directory record Official record
Conditions
Surgical Site Infection, Wound Surgical, Colorectal Disorders
Interventions
Primary Ostomy Closure with 0.1% Betaine/0.1% Polyhexanide Wound Irrigation, Pursestring Closure
Drug · Procedure
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
18 Years and older
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Jun 1, 2025 · Synced Sep 7, 2026, 11:34 AM EDT
Completed No phase listed Observational

Permanent Versus Delayed-Absorbable Monofilament Suture

NCT04506177
View directory record Official record
Conditions
Hysterectomy, Sacrocolpopexy
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
5
States / cities
Augusta, Georgia • Chicago, Illinois • Chapel Hill, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 25, 2024 · Synced Sep 7, 2026, 11:34 AM EDT
Active, not recruiting Not applicable Interventional

Barbed-suture Efficiency Study for Sacrocolpopexy

NCT05760794
View directory record Official record
Conditions
Prolapse; Female
Interventions
Non-barbed delayed absorbable suture, Barbed delayed absorbable suture
Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
21 Years to 80 Years · Female only
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 1, 2025 · Synced Sep 7, 2026, 11:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Non-Surgical Rhinoplasty Using PDO Threads

NCT04769427
View directory record Official record
Conditions
Nasal Defect
Interventions
PDO max threads
Device
Lead sponsor
DeNova Research
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 11, 2021 · Synced Sep 7, 2026, 11:34 AM EDT
Completed Not applicable Interventional Results available

A Randomized Controlled Trial of Permanent vs Absorbable Suture for Uterosacral Ligament Suspension

NCT02888093
View directory record Official record
Conditions
Pelvic Organ Prolapse, Cystocele, Uterine Prolapse
Interventions
Absorbent suture (polydioxanone) and Permanent suture (Gore-Tex CV2)
Device
Lead sponsor
Joseph Kowalski
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Dec 1, 2019 · Synced Sep 7, 2026, 11:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

To Show the Safety and Effectiveness of the Demetech Barbed Polydioxanone (PDO) Suture

NCT06404372
View directory record Official record
Conditions
Wrinkle
Interventions
Demetech Barbed PDO Suture
Device
Lead sponsor
Sutura Medical Technology LLC
Industry
Eligibility
22 Years and older
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
4
States / cities
Los Angeles, California • Sherman Oaks, California • The Woodlands, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Sep 7, 2026, 11:34 AM EDT
Completed Not applicable Interventional

Sacrocolpopexy With Posterior Repair Obstructed Defecation Symptoms

NCT03658395
View directory record Official record
Conditions
Vaginal Prolapse
Interventions
Laparoscopic Sacrocolopopexy, Posterior repair
Procedure
Lead sponsor
University of Oklahoma
Other
Eligibility
21 Years to 80 Years · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Dec 5, 2024 · Synced Sep 7, 2026, 11:34 AM EDT
Completed Not applicable Interventional Results available

Safety and Efficacy Study of Polydioxanone (PDS) Plates in Rhinoplasty

NCT01225250
View directory record Official record
Conditions
Rhinoplasty
Interventions
Polydioxanone (PDS) plates, Caudal septal extension graft performed through endonasal rhinoplasty
Device · Procedure
Lead sponsor
DeNova Research
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 3, 2020 · Synced Sep 7, 2026, 11:34 AM EDT
Not yet recruiting Not applicable Interventional

Barbed Suture vs Non-Barbed Closure for Emergency Exploratory Laparotomy RCT

NCT06043414
View directory record Official record
Conditions
Laparotomy, Dehiscence Wound, Surgical Site Infections, Trauma Abdomen, Emergency General Surgery
Interventions
triclosan-coated barbed suture, triclosan-coated non-barbed suture, Non-coated non-barbed suture
Device
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 100 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 27, 2023 · Synced Sep 7, 2026, 11:34 AM EDT