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ClinicalTrials.gov public records Last synced Oct 4, 2026, 11:59 PM EDT

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Showing 193–216 of 414 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Polysomnography (PSG) Clear all
Terminated No phase listed Observational

Evaluation of Sleep Disordered Breathing Following Ambulatory Surgery

NCT01851798
View directory record Official record
Conditions
Sleep Disordered Breathing
Interventions
Home sleep test administered to all enrolled subjects
Other
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
18 Years to 85 Years
Enrollment
203 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 15, 2015 · Synced Oct 4, 2026, 11:59 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Pathophysiology of the Upper Airway in Patients With COPD and Concomitant OSA

NCT02567448
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Sleep and pulmonary physiologic measurements
Other
Lead sponsor
University of California, San Diego
Other
Eligibility
40 Years to 70 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated May 7, 2020 · Synced Oct 4, 2026, 11:59 PM EDT
Completed Phase 3 Interventional Results available

Effects Of Pregabalin (Lyrica) On Sleep Maintenance In Subjects With Fibromyalgia

NCT00883740
View directory record Official record
Conditions
Fibromyalgia, Sleep Disorders
Interventions
Pregabalin, Placebo
Drug
Lead sponsor
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Industry
Eligibility
18 Years and older
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
30
States / cities
Phoenix, Arizona • Tucson, Arizona • San Diego, California + 22 more
Source: ClinicalTrials.gov public record
Updated Jan 25, 2021 · Synced Oct 4, 2026, 11:59 PM EDT
Completed Phase 3 Interventional Results available

Study to Assess the Efficacy and Safety of ACT-541468 (Daridorexant) in Adult and Elderly Subjects Suffering From Difficulties to Sleep

NCT03575104
View directory record Official record
Conditions
Insomnia Disorder
Interventions
Daridorexant, Placebo
Drug · Other
Lead sponsor
Idorsia Pharmaceuticals Ltd.
Industry
Eligibility
18 Years and older
Enrollment
924 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
37
States / cities
Glendale, Arizona • Tucson, Arizona • Little Rock, Arkansas + 33 more
Source: ClinicalTrials.gov public record
Updated Mar 25, 2022 · Synced Oct 4, 2026, 11:59 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

A High Density EEG Comparison of Sleep Patterns in Insomnia

NCT01960452
View directory record Official record
Conditions
Primary Insomnia
Interventions
Serial awakenings
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 45 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 9, 2025 · Synced Oct 4, 2026, 11:59 PM EDT
Completed Not applicable Interventional Results available

Improving the Sleep and Circadian Rhythms of Mechanically Ventilated Patients

NCT01284140
View directory record Official record
Conditions
Critical Illness, Sleep Deprivation, Respiratory Failure, Sleep Disorders, Circadian Rhythm
Interventions
Sleep and circadian rhythm promotion, Usual care
Behavioral
Lead sponsor
Brian Gehlbach
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
2
States / cities
Chicago, Illinois • Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 7, 2018 · Synced Oct 4, 2026, 11:59 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Atrial Fibrosis in Obstructive Sleep Apnea Patients: A Pilot Study

NCT04814420
View directory record Official record
Conditions
Atrial Fibrillation, Obstructive Sleep Apnea
Interventions
Delayed enhancement magnetic resonance imaging (DE-MRI)
Device
Lead sponsor
Tulane University
Other
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
3
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Oct 4, 2026, 11:59 PM EDT
Completed No phase listed Observational Results available

Comparison of Sleep Study Results After Partial Intracapsular Tonsillectomy Versus Total Tonsillectomy

NCT00887471
View directory record Official record
Conditions
Sleep-disordered Breathing, Obstructive Sleep Apnea
Interventions
PITA or T&A
Procedure
Lead sponsor
State University of New York - Downstate Medical Center
Other
Eligibility
6 Months to 14 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Feb 10, 2014 · Synced Oct 4, 2026, 11:59 PM EDT
Not yet recruiting Early Phase 1 Interventional Accepts healthy volunteers

Impacts of Opioids on Respiratory Drive During Sleep

NCT06854211
View directory record Official record
Conditions
Opioids, Obstructive Sleep Apnea (OSA)
Interventions
Morphine p.o., Placebo
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 29, 2026 · Synced Oct 4, 2026, 11:59 PM EDT
Completed Phase 4 Interventional

Sleep Intervention During Acute Lung Injury

NCT01050699
View directory record Official record
Conditions
Critical Illness, Sleep, Acute Lung Injury, Acute Respiratory Distress Syndrome
Interventions
Dexmedetomidine, Midazolam and Fentanyl
Drug
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 85 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2019
U.S. locations
2
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 4, 2021 · Synced Oct 4, 2026, 11:59 PM EDT
Completed Phase 2 Interventional Results available

A Pivotal Study to Assess the Effectiveness of Nasal Dilator (Breathe Right Nasal Strips)

NCT03549130
View directory record Official record
Conditions
Congestion, Nasal
Interventions
Breathe Right Tan (small/medium) nasal strips, Placebo nasal strip
Device · Other
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years and older
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
2
States / cities
Indianapolis, Indiana • Paramus, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 25, 2018 · Synced Oct 4, 2026, 11:59 PM EDT
Completed Phase 4 Interventional

12-week Polysomnography Study of Ropinirole Controlled Release for Restless Legs Syndrome

NCT00373542
View directory record Official record
Conditions
Restless Legs Syndrome (RLS), Restless Legs Syndrome
Interventions
ropinirole CR-RLS
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 79 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
45
States / cities
Jasper, Alabama • Tuscaloosa, Alabama • Phoenix, Arizona + 41 more
Source: ClinicalTrials.gov public record
Updated Oct 28, 2016 · Synced Oct 4, 2026, 11:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Revised Algorithm for Next Generation DeVilbiss Healthcare AutoAdjust Continuous Positive Airway Pressure (CPAP)

NCT01797705
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
DeVilbiss AutoAdjust CPAP with revised algorithm
Device
Lead sponsor
DeVilbiss Healthcare LLC
Industry
Eligibility
21 Years to 75 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Newton, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 29, 2015 · Synced Oct 4, 2026, 11:59 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Effect of Sleep Loss on Emotion Regulation

NCT05393830
View directory record Official record
Conditions
Sleep, Insomnia, Sleep Deprivation
Interventions
Sleep Restriction
Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 40 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Oct 4, 2026, 11:59 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Circadian Rhythms and Homeostatic Sleep Drive and Their Effect on Reward and Cognitive Control Systems in Adolescents

NCT05336084
View directory record Official record
Conditions
Sleep
Interventions
Ultradian sleep/wake protocol
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
13 Years to 18 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2030
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Oct 4, 2026, 11:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Locus-coeruleus Function in Normal Elderly and AD Risk

NCT04403165
View directory record Official record
Conditions
Alzheimer Disease
Interventions
Nocturnal polysomnography (NPSG), Lumbar Puncture (LP), PET-MR measurement with a norepinephrine transporter (NET)-selective radiotracer (S,S)-[11C]Omethylreboxetine ([11C]MRB), Psychomotor Vigilance Task (PVT)
Procedure · Other · Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
55 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Oct 4, 2026, 11:59 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Changes in Upper Airway Anatomy, Quality of Life Measures, and Polysomnographic Parameters Using A Functional Dental Appliance

NCT02805764
View directory record Official record
Conditions
Obstructive Sleep Apnea, Malocclusion
Interventions
Homeoblock
Device
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Feb 5, 2019 · Synced Oct 4, 2026, 11:59 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Cerebral Blood Flow and Childhood Obstructive Sleep Apnea

NCT02995837
View directory record Official record
Conditions
Obstructive Sleep Apnea Syndrome
Interventions
Sleep Study, Neurocognitive Testing, CBF During Wakefulness, CBF During Sleep
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
6 Years to 12 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 9, 2024 · Synced Oct 4, 2026, 11:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Variable Negative External Pressure (vNEP) - An Alternative to Continuous Positive Airway Pressure (CPAP) for the Treatment of Obstructive Sleep Apnea (OSA): A Pilot Study

NCT04718142
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
vNEP
Device
Lead sponsor
Somne, LLC
Industry
Eligibility
18 Years to 65 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
San Leandro, California
Source: ClinicalTrials.gov public record
Updated Apr 2, 2021 · Synced Oct 4, 2026, 11:59 PM EDT
Withdrawn Not applicable Interventional

Effects of Treating Sleep Apnea in Patients With Congestive Heart Failure

NCT01997866
View directory record Official record
Conditions
Obstructive Sleep Apnea, Sleep Apnea, Congestive Heart Failure, Heart Failure
Interventions
STOP-BANG Scoring Model, Polysomnogram Sleep Study
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 110 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated May 17, 2017 · Synced Oct 4, 2026, 11:59 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

OSA in Pregnant Women With Chronic HTN

NCT03230110
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Pregnancy, Hypertension
Interventions
WP200U home sleep study device
Diagnostic Test
Lead sponsor
Duke University
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
2
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 24, 2019 · Synced Oct 4, 2026, 11:59 PM EDT
Completed Not applicable Interventional

Workflow Validation of an In-Home Feedback Controlled Mandibular Positioner

NCT03616327
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
MATRx in-lab, MATRx plus
Device
Lead sponsor
Zephyr Sleep Technologies
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 21, 2019 · Synced Oct 4, 2026, 11:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Expansion of the Weigh Smart Pediatric Group Family Oriented Weight Management Program Through the Use of Telehealth

NCT04521595
View directory record Official record
Conditions
Pediatric Obesity
Interventions
Weigh Smart Telehealth intervention
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
7 Years to 17 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 20, 2021 · Synced Oct 4, 2026, 11:59 PM EDT
Terminated Phase 1 Interventional

How Your Patients' Non-REM Sleep Changes On Sedatives in the Intensive Care Units

NCT00826553
View directory record Official record
Conditions
Delirium, Respiratory Failure
Interventions
Dexmedetomidine, GABA agonist
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 5, 2017 · Synced Oct 4, 2026, 11:59 PM EDT