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ClinicalTrials.gov public records Last synced Oct 29, 2026, 4:05 AM EDT

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Showing 1–24 of 201 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Positive Affect Clear all
Completed Not applicable Interventional

Web-Delivered Interventions for Blood Sugar Control for Individuals With Type 2 Diabetes

NCT02676648
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
Multicomponent online program, Breath meter, Text messages, Diet-appropriate foods and cookbooks
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 9, 2021 · Synced Oct 29, 2026, 4:05 AM EDT
Completed Not applicable Interventional Results available

Internet-Delivered Positive Affect Program in Managing Emotion in Young Adult Cancer Survivors

NCT02832154
View directory record Official record
Conditions
Cancer Survivor
Interventions
Internet-Based Intervention, Quality-of-Life Assessment, Questionnaire Administration
Other · Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 39 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
2
States / cities
Chicago, Illinois • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 16, 2020 · Synced Oct 29, 2026, 4:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study of Affect Induction for Lab Induced Pain in Healthy Undergraduates

NCT05619419
View directory record Official record
Conditions
Meditation, Pain, Mindfulness, Affect, Emotion Regulation
Interventions
Mindfulness-enhanced positive affect induction, Breathing Meditation
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 65 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 22, 2023 · Synced Oct 29, 2026, 4:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Optimizing Mindfulness Based Cognitive Therapy (MBCT) Maintenance

NCT05859386
View directory record Official record
Conditions
Depression
Interventions
Mindfulness maintenance program
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 3, 2024 · Synced Oct 29, 2026, 4:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Sleep Disparities in Minority Children

NCT01301989
View directory record Official record
Conditions
Sleep
Interventions
Sleep Counselor Intervention, Sleep Education Control
Behavioral · Other
Lead sponsor
Columbia University
Other
Eligibility
60 Months to 87 Months
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 4, 2015 · Synced Oct 29, 2026, 4:05 AM EDT
Withdrawn No phase listed Observational

Neurocardiac Interactions Evaluated by Anatomic and Physiologic MRI Assessment

NCT02962154
View directory record Official record
Conditions
Ischemia, Stress, Mental
Interventions
Coronary CT Angiography, Mood Symptom Scale, Anxiety Symptom Scale, Chronic Stress Inventories, Psychosocial Function Questionnaires, General Health and quality of life questionnaires, Magnetic Resonance Imaging
Radiation · Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
50 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 9, 2018 · Synced Oct 29, 2026, 4:05 AM EDT
Completed Not applicable Interventional Results available

Trial on the Effect of E-cigarette Advertising on Cigarette Perceptions in Adolescents

NCT03786042
View directory record Official record
Conditions
Attentional Bias, Smoking Cues, Positive Perceptions About Cigarette Smoking, Social Norms, Smoking Susceptibility
Interventions
E-cigarette ad exposure, non e-cigarette TV commercials
Behavioral · Other
Lead sponsor
Trustees of Dartmouth College
Other
Eligibility
14 Years to 17 Years
Enrollment
139 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Sep 26, 2025 · Synced Oct 29, 2026, 4:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility of a Mind-Body Intervention for Optimism

NCT07862478
View directory record Official record
Conditions
Emotional Well-being, Psychological Stress, Cardiovascular Risk
Interventions
Emotional Well-Being Writing, Chair-Assisted Squats, Slow-Paced Breathing
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
40 Years to 65 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 29, 2026, 4:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Skin Savvy Study: A Behavioral Skin Cancer Prevention Intervention

NCT00709306
View directory record Official record
Conditions
Skin Cancer Prevention
Interventions
UV-Detect Photos, Motivational Interviewing, Education
Device · Behavioral
Lead sponsor
Fox Chase Cancer Center
Other
Eligibility
18 Years to 24 Years
Enrollment
197 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2010
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 31, 2018 · Synced Oct 29, 2026, 4:05 AM EDT
Not listed No phase listed Observational

Interconception Care at the University of Mississippi Medical Center

NCT03024385
View directory record Official record
Conditions
Maternal Behavior, Depression
Interventions
Well Child Visits
Behavioral
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
13 Years to 67 Years
Enrollment
1,625 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2026
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Apr 27, 2020 · Synced Oct 29, 2026, 4:05 AM EDT
Completed Phase 1 Interventional

Ritonavir and Its Effects on Biomarkers in Women Undergoing Surgery for Newly Diagnosed Breast Cancer

NCT01009437
View directory record Official record
Conditions
Breast Cancer
Interventions
ritonavir, therapeutic conventional surgery
Drug · Procedure
Lead sponsor
Masonic Cancer Center, University of Minnesota
Other
Eligibility
18 Years and older · Female only
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
2
States / cities
Minneapolis, Minnesota • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 5, 2017 · Synced Oct 29, 2026, 4:05 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

An mHealth Intervention to Improve HIV Prevention Service Engagement Among People Who Use Drugs

NCT06068283
View directory record Official record
Conditions
HIV Infections
Interventions
LOTUS mHealth Intervention Group
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jun 26, 2026 · Synced Oct 29, 2026, 4:05 AM EDT
Completed Not applicable Interventional Results available

Compassion Meditation for PTSD

NCT02372396
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Compassion Meditation (CM), Relaxation
Behavioral
Lead sponsor
Veterans Medical Research Foundation
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 5, 2018 · Synced Oct 29, 2026, 4:05 AM EDT
Completed Not applicable Interventional Results available

Version 2 of the Smoking Cessation Smartphone App "Smiling Instead of Smoking" (SiS)

NCT03951766
View directory record Official record
Conditions
Smoking Cessation, Smoking, Tobacco
Interventions
Smiling Instead of Smoking (SiS) App Version 2
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 26, 2022 · Synced Oct 29, 2026, 4:05 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Compassion Fatigue in ED Providers

NCT03070249
View directory record Official record
Conditions
Compassion Fatigue
Interventions
Professional Quality of Life (ProQoL) scale
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 24, 2017 · Synced Oct 29, 2026, 4:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Life Enhancing Activities for Family Caregivers

NCT01825681
View directory record Official record
Conditions
Stress, Dementia, Affect
Interventions
Positive Affect
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
175 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2019
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 5, 2019 · Synced Oct 29, 2026, 4:05 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Development of Positive Psychotherapy for Smoking Cessation

NCT01451814
View directory record Official record
Conditions
Smoking
Interventions
Positive Psychotherapy for smoking cessation, Nicotine polacrilex, Relaxation training, Behavioral smoking cessation treatment
Behavioral · Drug
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 18, 2015 · Synced Oct 29, 2026, 4:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

CEDARS Intervention: A Coping, Emotional Development, & Stress Reduction Intervention

NCT04958694
View directory record Official record
Conditions
Adolescent Behavior, Stress Reduction, Adverse Childhood Experiences, Positive Attitude
Interventions
CEDARS
Behavioral
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
14 Years to 19 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 29, 2026, 4:05 AM EDT
Completed Not applicable Interventional

Incorporating Positive Affect Promoting Activities Into Cognitive Behavioral Therapies

NCT06432959
View directory record Official record
Conditions
Depression, Borderline Personality Disorder, Emotion Regulation
Interventions
Psychotherapy, Positive Affect Promoting Activities, Psychotherapy
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 22, 2025 · Synced Oct 29, 2026, 4:05 AM EDT
Completed Not applicable Interventional Results available

Problem Adaptation Therapy for Mild Cognitive Impairment and Depression

NCT03043573
View directory record Official record
Conditions
Cognitive Impairment, Depression
Interventions
PATH-MCI, Supportive Therapy
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
60 Years to 85 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
4
States / cities
Baltimore, Maryland • New York, New York • The Bronx, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 12, 2025 · Synced Oct 29, 2026, 4:05 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

eMOTION: Examining Implicit Attitudes in Physical Activity Engagement

NCT07044570
View directory record Official record
Conditions
Physical Activity, Overweight or Obesity, Cancer
Interventions
Physical Activity Goals mHealth Intervention, TYPE/CONTEXT enhancement, SAVOR enhancement
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
151 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 28, 2026 · Synced Oct 29, 2026, 4:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Positive Affect as a Source of Resilience for Adults in Chronic Pain

NCT04869345
View directory record Official record
Conditions
Geriatric, Chronic Pain
Interventions
LARKSPUR
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
50 Years and older
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 1, 2023 · Synced Oct 29, 2026, 4:05 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Study to Find Out How Multiple Doses of BIIB091 Affect the Electrical Activity of the Heart in Healthy Participants

NCT06574828
View directory record Official record
Conditions
Healthy Volunteer
Interventions
BIIB091, Moxifloxacin, BIIB091-matched Placebo, Moxifloxacin-matched Placebo
Drug
Lead sponsor
Biogen
Industry
Eligibility
18 Years to 55 Years
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Mar 28, 2025 · Synced Oct 29, 2026, 4:05 AM EDT
Active, not recruiting Not applicable Interventional

A Behavioral mHealth Intervention for People With HIV With Anxiety and Depression

NCT07112001
View directory record Official record
Conditions
HIV, Depression, Anxiety
Interventions
PositiveLinks with Counseling, Standard of Care (SOC)
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 90 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 29, 2026, 4:05 AM EDT