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ClinicalTrials.gov public records Last synced Oct 30, 2026, 2:22 AM EDT

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Showing 145–168 of 201 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Positive Affect Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

eMOTION Formative Study

NCT06125964
View directory record Official record
Conditions
Physical Inactivity, Overweight or Obesity, Cancer
Interventions
Intensity-Based Goals, Affect-Based Goals, TYPE/CONTEXT Enhancement, SAVOR Enhancement
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 14, 2025 · Synced Oct 30, 2026, 2:22 AM EDT
Completed Not applicable Interventional

Peer-enhanced Intervention to Support Teen Weight Loss

NCT00285558
View directory record Official record
Conditions
Obesity
Interventions
CBT with peer-enhanced activities, CBT with supervised aerobic exercise
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
13 Years to 16 Years
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 6, 2017 · Synced Oct 30, 2026, 2:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparing Acceptance and Commitment Therapy (ACT) and Cognitive Therapy (CT) for Test Anxiety

NCT00850226
View directory record Official record
Conditions
Anxiety
Interventions
CT, ACT
Behavioral
Lead sponsor
Drexel University
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 2, 2010 · Synced Oct 30, 2026, 2:22 AM EDT
Recruiting Not applicable Interventional

Psychological Options for Wellness and Recovery (POWeR) Trial for Veterans With Chronic Back/Neck Pain

NCT07137715
View directory record Official record
Conditions
Chronic Pain, Back Pain, Back Pain Lower Back Chronic, Neck Pain
Interventions
Pain reprocessing therapy (PRT), Cognitive Behavioral Therapy for Chronic Pain (CBT-CP), Usual Care
Behavioral · Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Oct 30, 2026, 2:22 AM EDT
Active, not recruiting Not applicable Interventional

Trauma Intervention to Optimize PrEP Among Women Who Inject Drugs

NCT05192434
View directory record Official record
Conditions
HIV Infections, Opioid Use, Trauma, Psychological
Interventions
Expressive Writing, Contingency Management
Behavioral
Lead sponsor
Drexel University
Other
Eligibility
18 Years and older · Female only
Enrollment
219 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Oct 30, 2026, 2:22 AM EDT
Recruiting No phase listed Observational

Collecting Information About Treatment Results for Patients With Cushing's Syndrome

NCT03364803
View directory record Official record
Conditions
Cushing's Disease, Cushing Syndrome, Cushing Disease
Interventions
Cushing's QoL (Quality of Life Questionnaire), Nottingham Health Profile (NHP), Hospital Anxiety and Depression Scale (HADS), Perceived Stress Scale (PSS), Barratt's Impulsivity Scale (BIS), Beck Depression Inventory (BDI), State-Trait Anxiety Inventory (STAI), State Food Craving Questionnaire-State (FCQ-S), Trait Food Craving Questionnaire-Trait (FCQ-T), Visual Analogue Scale (VAS), Sensitivity to Reinforcement of Addictive and other Primary Rewards (STRAP-R) food variant
Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
14 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2026
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Oct 26, 2026 · Synced Oct 30, 2026, 2:22 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Engaging Motivation for the Prevention of Weight Regain

NCT01169428
View directory record Official record
Conditions
Obesity
Interventions
Mindfulness Based Weight Loss Maintenance (MBWLM), Behavioral: Standard Behavioral Weight-Loss Maintenence
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
2
States / cities
Durham, North Carolina • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 14, 2013 · Synced Oct 30, 2026, 2:22 AM EDT
Active, not recruiting Not applicable Interventional

Neuroscience-informed Treatment to Remotely Target Reward Mechanisms in Post-acute Anorexia Nervosa

NCT05799872
View directory record Official record
Conditions
Anorexia Nervosa
Interventions
Positive Affect Treatment for Anorexia Nervosa (PAT-AN):, Psychoeducational and Behavioral Therapy (PBT)
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 27, 2026 · Synced Oct 30, 2026, 2:22 AM EDT
Completed Not applicable Interventional

A Randomized Trial of Changing Medication Adherence In Hypertensive African-American Patients

NCT00248872
View directory record Official record
Conditions
Hypertension
Interventions
Intervention Group
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 110 Years
Enrollment
278 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 23, 2017 · Synced Oct 30, 2026, 2:22 AM EDT
Completed Phase 1Phase 2 Interventional Results available

The University of Michigan Wellness for Liver Health Study

NCT05010070
View directory record Official record
Conditions
Nonalcoholic Fatty Liver Disease
Interventions
diet and lifestyle program
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Oct 30, 2026, 2:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Positive Affect as a Source of Resilience for Adults in Chronic Pain

NCT04869345
View directory record Official record
Conditions
Geriatric, Chronic Pain
Interventions
LARKSPUR
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
50 Years and older
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 1, 2023 · Synced Oct 30, 2026, 2:22 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Stress and Anxiety Effects on Valuation

NCT07252947
View directory record Official record
Conditions
Reward Value Level
Interventions
Socially Evaluated Cold Pressor Task (SECPT), Non-Stressful Control Task
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 65 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Oct 30, 2026, 2:22 AM EDT
Enrolling by invitation Not applicable Interventional

Career Enhancement Training Study Delivered Across Career Phases

NCT05967364
View directory record Official record
Conditions
Suicide Prevention, Suicide
Interventions
Wingman-Connect, Stress Management
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years to 40 Years
Enrollment
2,970 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Mar 20, 2026 · Synced Oct 30, 2026, 2:22 AM EDT
Recruiting Not applicable Interventional

Examining the Effectiveness of the Early Start Denver Model in Community Programs Serving Young Autism

NCT06005285
View directory record Official record
Conditions
Autism
Interventions
Early Start Denver Model (ESDM), Early Intensive Behavioral Intervention (EIBI)
Behavioral
Lead sponsor
University of California, Davis
Other
Eligibility
12 Months and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Dec 5, 2025 · Synced Oct 30, 2026, 2:22 AM EDT
Completed Not applicable Interventional Results available

A Proof-of-Concept Trial of a Positive Psychology Intervention for Allogeneic Stem Cell Transplant Patients

NCT03654404
View directory record Official record
Conditions
Hematologic Malignancy, Hematopoietic/Lymphoid Cancer, Blood Cancer
Interventions
Positive Psychology Intervention
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 90 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Oct 30, 2026, 2:22 AM EDT
Completed Not applicable Interventional Results available

Treatment, Emotion, and Neuromodulation of Depression (TREND) Study

NCT05436379
View directory record Official record
Conditions
Depression
Interventions
Theta Burst Stimulation
Device
Lead sponsor
Erika Forbes
Other
Eligibility
18 Years to 26 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Oct 30, 2026, 2:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Neuronal and Behavioral Effects of Implicit Priming in Obese Individuals

NCT02347527
View directory record Official record
Conditions
Feeding Behavior, Obesity, Overweight
Interventions
Active Implicit Priming, Control Implicit Priming
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
21 Years to 65 Years
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2019
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 7, 2022 · Synced Oct 30, 2026, 2:22 AM EDT
Completed Not applicable Interventional Results available

The Effect of Questionnaire Content on Measures of Pain Intensity, Magnitude of Disability, and Symptoms of Depression in Patients With Arm Illness

NCT02209259
View directory record Official record
Conditions
Arm Illness
Interventions
PROMIS Upper Extremity Function, Pain intensity, PROMIS depression, Positive affect negative affect scale (PANAS), standard PCS, positively-adjusted version of the PCS
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
168 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 14, 2018 · Synced Oct 30, 2026, 2:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Life Enhancing Activities for Family Caregivers

NCT01825681
View directory record Official record
Conditions
Stress, Dementia, Affect
Interventions
Positive Affect
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
175 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2019
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 5, 2019 · Synced Oct 30, 2026, 2:22 AM EDT
Completed Not applicable Interventional Results available

Cognitive-Behavioral Therapy and Supportive Psychotherapy for Body Dysmorphic Disorder

NCT01453439
View directory record Official record
Conditions
Body Dysmorphic Disorder, Obsessive-Compulsive Spectrum Disorder, Anxiety Disorders, Somatoform Disorders
Interventions
Cognitive Behavioral Therapy, Supportive Psychotherapy
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
2
States / cities
Boston, Massachusetts • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 15, 2020 · Synced Oct 30, 2026, 2:22 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Positive Affect Treatment for Adolescents With Early Life Adversity

NCT06273137
View directory record Official record
Conditions
Depression
Interventions
Positive affect treatment, Supportive psychotherapy (SUP)
Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
12 Years to 16 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2030
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 30, 2026, 2:22 AM EDT
Terminated Not applicable Interventional

Serving Women Using Opioids During Pregnancy

NCT03552120
View directory record Official record
Conditions
Opioid Use, Pregnancy Related
Interventions
MORE, Supportive Psychotherapy
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 24, 2023 · Synced Oct 30, 2026, 2:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A 14 Week Study of Mindfulness Effects on Attentional Control in Older Adults

NCT02714426
View directory record Official record
Conditions
Cognitive Aging
Interventions
Mindfulness-inspired treatment, Brain health
Behavioral · Other
Lead sponsor
University of Florida
Other
Eligibility
65 Years and older
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 7, 2019 · Synced Oct 30, 2026, 2:22 AM EDT
Completed Phase 2 Interventional

A Pilot Study of the Effects of Diet and Behavioral Interventions on Health in Diabetics

NCT01713764
View directory record Official record
Conditions
Diabetes Type II
Interventions
Low Carbohydrate Diet, American Diabetes Association Diet, Mindfulness and Positive Affect Skills
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 30, 2013 · Synced Oct 30, 2026, 2:22 AM EDT