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ClinicalTrials.gov public records Last synced Oct 22, 2026, 12:59 AM EDT

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Showing 1–24 of 31 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Positive Air Pressure Device Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Non-invasive Tidal Volume Monitoring Using the Linshom Respiratory Monitoring Device

NCT03279458
View directory record Official record
Conditions
Pulmonary Ventilation, Capnography
Interventions
Linshom Respiratory Monitoring Device
Device
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Jul 5, 2018 · Synced Oct 22, 2026, 12:59 AM EDT
Recruiting Not applicable Interventional

HFNC vs NIPPV Following Extubation

NCT05869825
View directory record Official record
Conditions
Congenital Heart Disease
Interventions
High Flow Nasal Canula following extubation, Non-Invasive Positive Pressure Ventilation following extubation
Procedure
Lead sponsor
Emory University
Other
Eligibility
Up to 1 Year
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Oct 22, 2026, 12:59 AM EDT
Completed Phase 2 Interventional Results available

High Flow Oxygen and Bilevel Airway Pressure for Persistent Dyspnea in Patients With Advanced Cancer

NCT00934128
View directory record Official record
Conditions
Advanced Cancers
Interventions
Vapotherm, BIPAP
Device
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 2, 2016 · Synced Oct 22, 2026, 12:59 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Stroke and CPAP Outcome Study: A Sham-controlled Trial of CPAP Among Stroke Rehabilitation Patients

NCT02551757
View directory record Official record
Conditions
Stroke, Sleep Apnea, Obstructive
Interventions
Auto-titrating CPAP, Sham-CPAP
Device
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 13, 2021 · Synced Oct 22, 2026, 12:59 AM EDT
Completed No phase listed Observational

Delineating Swallowing Impairment and Decline in ALS

NCT02962050
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis
Interventions
Videofluoroscopic Swallowing Study (VFSS), Voluntary Peak Cough Flow Testing, Iowa Oral Performance Instrument, Capsaicin Challenge, Pulmonary Function Testing, Eating Assessment Tool 10, The Center for Neurologic Study Bulbar Function Scale
Procedure · Device · Drug + 1 more
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 90 Years
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
2
States / cities
Gainesville, Florida • Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Feb 23, 2023 · Synced Oct 22, 2026, 12:59 AM EDT
Terminated Phase 1Phase 2 Interventional Results available

Project 4A: Inspiratory Muscle Training and Diaphragm Strength

NCT02367170
View directory record Official record
Conditions
Sepsis
Interventions
Bilateral phrenic nerve stimulation and measurement of transdiaphragmatic pressure, Midazolam, Volitional Measurement of Maximal Inspiratory Pressure (MIP), Inspiratory Muscle Strength Training (IMST), SHAM Inspiratory Muscle Strength Training (IMST), Diaphragm thickness measurement, Blood and Urine samples
Procedure · Drug · Device + 1 more
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated May 7, 2018 · Synced Oct 22, 2026, 12:59 AM EDT
Completed Not applicable Interventional Results available

Vitabreath Pilot in Chronic Obstructive Pulmonary Disease (COPD) Patients

NCT03349437
View directory record Official record
Conditions
COPD, Dyspnea
Interventions
Vitabreath Device, Pursed Lip Breathing
Device · Other
Lead sponsor
Philips Respironics
Industry
Eligibility
40 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
2
States / cities
Youngstown, Ohio • Jefferson Hills, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 8, 2019 · Synced Oct 22, 2026, 12:59 AM EDT
Withdrawn Not applicable Interventional

Initiation of Auto-adjusting CPAP for Newly Diagnosed OSA in Hospitalized Patients

NCT01556464
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Auto-adjusting CPAP
Device
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 10, 2018 · Synced Oct 22, 2026, 12:59 AM EDT
Withdrawn Not applicable Interventional

Comparison of High-flow Oxygen With or Without Nasal Positive Airway Pressure (PAP) During Propofol Sedation for Colonoscopy in an Ambulatory Surgical Center

NCT05754255
View directory record Official record
Conditions
Colonoscopy, Positive-Pressure Respiration
Interventions
Nasal Cannula, Nasal Positive Airway Pressure System
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Oct 22, 2026, 12:59 AM EDT
Not listed Phase 1Phase 2 Interventional

Effects of Positive Airway Pressure (PAP) in Children With Obstructive Sleep Apnea (OSA)

NCT01156649
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
PAP therapy, Sham PAP therapy
Device
Lead sponsor
University of Tennessee
Other
Eligibility
6 Years to 12 Years
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 4, 2016 · Synced Oct 22, 2026, 12:59 AM EDT
Completed Not applicable Interventional Results available

Sleep-Disordered Breathing and PAP in Perinatal Depression

NCT02507297
View directory record Official record
Conditions
Sleep-disordered Breathing, Major Depressive Disorder
Interventions
Positive Airway Pressure (PAP)
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 1, 2023 · Synced Oct 22, 2026, 12:59 AM EDT
Recruiting Not applicable Interventional

The Effects of Successful OSA Treatment on Memory and AD Biomarkers in Older Adults Study

NCT05988385
View directory record Official record
Conditions
Obstructive Sleep Apnea, Cognitive Decline
Interventions
Positive airway pressure, Oral appliance therapy, Positional therapy
Device
Lead sponsor
California Pacific Medical Center Research Institute
Other
Eligibility
55 Years to 85 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
4
States / cities
Tucson, Arizona • New York, New York • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 22, 2026, 12:59 AM EDT
Completed Not applicable Interventional Results available

ALS and Airway Clearance (ALSAC) Therapy

NCT04947436
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis, Respiratory Muscle Weakness
Interventions
High Frequency Chest Wall Oscillation, Mechanical insufflation/exsufflation
Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
21 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Nov 4, 2021 · Synced Oct 22, 2026, 12:59 AM EDT
Not listed Not applicable Interventional

Oscillating Positive Expiratory Pressure (OPEP) Therapy in Trauma Patients With Multiple Rib Fractures

NCT04100512
View directory record Official record
Conditions
Rib Fractures, Respiratory Complication
Interventions
Oscillating Positive Expiratory Pressure Device, Incentive spirometry
Device
Lead sponsor
Poudre Valley Health System
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Loveland, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 19, 2022 · Synced Oct 22, 2026, 12:59 AM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

Muscle Function After Childbirth

NCT05073224
View directory record Official record
Conditions
Postpartum, Muscle Fatigue, Force Steadiness, Nulligravid, Muscle Weakness
Interventions
Active Straight Leg Raise Test, Active Straight Leg Raise Fatigue Task, Lower Extremity Strength Testing, Ultrasound imaging of abdominal wall
Diagnostic Test · Other
Lead sponsor
Carroll University
Other
Eligibility
20 Years to 35 Years · Female only
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Waukesha, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Oct 22, 2026, 12:59 AM EDT
Recruiting Not applicable Interventional

Effect of CPAP on 6-Minute Walk Test Outcomes in Patients With ECAC

NCT04217603
View directory record Official record
Conditions
Tracheobronchomalacia, Excessive Dynamic Airway Collapse
Interventions
Continuous positive airway pressure (CPAP) device, Sham-continuous positive airway pressure (CPAP) device
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 22, 2026, 12:59 AM EDT
Terminated Not applicable Interventional

Airway Secretion Clearance in Cystic Fibrosis

NCT00839644
View directory record Official record
Conditions
Cystic Fibrosis
Interventions
High frequency chest wall oscillation, Oscillatory Positive Expiratory Pressure, PD&P: Postural drainage and percussion
Device · Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
7 Years and older
Enrollment
166 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2003
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 2, 2012 · Synced Oct 22, 2026, 12:59 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Improving Diagnostic Standards in Dysphagia

NCT04773184
View directory record Official record
Conditions
Dysphagia
Interventions
Fiberoptic Endoscopic Evaluation of Swallowing, Videofluoroscopic Swallowing Study, Voluntary Peak Cough Flow Testing, Iowa Oral Performance Instrument, Capsaicin Challenge, Pulmonary Function Testing, Voicing Tasks
Procedure · Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 90 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 17, 2024 · Synced Oct 22, 2026, 12:59 AM EDT
Recruiting Not applicable Interventional

Postpartum Exercise Intervention

NCT07613333
View directory record Official record
Conditions
Postpartum, Neuromuscular Adaptations, Abdominal Muscles, Pelvic Floor Dysfunctions, Physical Activity
Interventions
Progressive exercise, Active Straight Leg Raise Test, Active Straight Leg Raise Fatigue Task, Lower Extremity Strength Testing, Ultrasound imaging of abdominal wall, Pelvic Floor Muscle Strength Testing, Pelvic Floor Muscle Endurance Testing
Other · Diagnostic Test
Lead sponsor
Carroll University
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Waukesha, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 29, 2026 · Synced Oct 22, 2026, 12:59 AM EDT
Recruiting Not applicable Interventional

Non-invasive Ventilation in Reducing the Need for Intubation in Patients With Cancer and Respiratory Failure

NCT02464696
View directory record Official record
Conditions
Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Interventions
Methylprednisolone, Oxygen Therapy, Positive Air Pressure Device
Drug · Procedure · Device
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
256 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 22, 2026, 12:59 AM EDT
Terminated Phase 4 Interventional Results available

Palatal Implants in Combination With Continuous Positive Airway Pressure to Treat Obstructive Sleep Apnea

NCT00730041
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
Pillar Palatal Implant System, Sham system
Device
Lead sponsor
Medtronic Xomed, Inc.
Industry
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
7
States / cities
Little Rock, Arkansas • Berkeley, California • Denver, Colorado + 4 more
Source: ClinicalTrials.gov public record
Updated Jan 12, 2010 · Synced Oct 22, 2026, 12:59 AM EDT
Completed Not applicable Interventional

Multidisciplinary Approach to the Treatment of Insomnia and Comorbid Sleep Apnea

NCT01785303
View directory record Official record
Conditions
Obstructive Sleep Apnea, Insomnia
Interventions
CBT-I, CPAP
Behavioral · Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 18, 2019 · Synced Oct 22, 2026, 12:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating the Efficacy of PAP Therapy for Treating OSA in the Home Environment

NCT04744038
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
Positive Airway Pressure (PAP) Therapy
Device
Lead sponsor
ResMed
Industry
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 13, 2021 · Synced Oct 22, 2026, 12:59 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Impact of Insomnia on Pain in HIV

NCT04298658
View directory record Official record
Conditions
HIV, Insomnia
Interventions
Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders-5 (DSM-5)sleep disorders-revised, Resmed ApneaLink Air device (Resmed, San Diego, CA)., Quantitative Sensory testing (QST), OraQuick Advance Rapid HIV 1/2 Swab test, Cluster of Differentiation 4 (CD4) and Viral load
Diagnostic Test · Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 85 Years
Enrollment
171 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 17, 2025 · Synced Oct 22, 2026, 12:59 AM EDT