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Showing 1–20 of 20 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Positive Psychology (PP) intervention Clear all
Completed Not applicable Interventional

Well-being in IBS: Strengths and Happiness (WISH)

NCT05289089
View directory record Official record
Conditions
Irritable Bowel Syndrome
Interventions
Positive Psychology Intervention
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 21, 2025 · Synced Sep 1, 2026, 7:43 PM EDT
Completed Not applicable Interventional

Positive Psychology for ACS Patients: a Factorial Design Study

NCT02754895
View directory record Official record
Conditions
Acute Coronary Syndrome
Interventions
Positive Psychology (PP), Motivational Interviewing (MI)
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 31, 2017 · Synced Sep 1, 2026, 7:43 PM EDT
Recruiting Not applicable Interventional

Well-being in IBS: Strengths and Happiness (WISH) 2.0

NCT06866106
View directory record Official record
Conditions
Irritable Bowel Syndrome
Interventions
Positive Psychology (PP) Intervention, Educational Intervention
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 21, 2026 · Synced Sep 1, 2026, 7:43 PM EDT
Recruiting Not applicable Interventional

Promoting Well-being and Health in Heart Failure

NCT04829617
View directory record Official record
Conditions
Heart Failure, Heart Failure NYHA Class I, Heart Failure NYHA Class II, Heart Failure NYHA Class III
Interventions
PP-MI Intervention, MI-alone Intervention
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Sep 1, 2026, 7:43 PM EDT
Completed Not applicable Interventional Results available

Developing a Positive Psychology Intervention to Promote Health Behaviors in Metabolic Syndrome: Proof-of Concept Trial

NCT03473886
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
Intervention arm: PP-MI
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 100 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 11, 2020 · Synced Sep 1, 2026, 7:43 PM EDT
Completed Not applicable Interventional Results available

A Psychological-behavioral Intervention for Physical Activity in Type 2 Diabetes

NCT03150199
View directory record Official record
Conditions
Type2 Diabetes
Interventions
Positive Psychology + Motivational Interviewing, MI-based Health Education Intervention
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 18, 2020 · Synced Sep 1, 2026, 7:43 PM EDT
Completed Not applicable Interventional Results available

A Psychological-behavioral Intervention to Increase Activity in Type 2 Diabetes

NCT03164538
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
Positive Psychology + Motivational Interviewing, Diabetes Education
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 20, 2021 · Synced Sep 1, 2026, 7:43 PM EDT
Not listed Not applicable Interventional

Internet-based Positive Psychological Intervention for Hispanic/Latino Adult With Hypertension in a Primary Care Setting

NCT03892057
View directory record Official record
Conditions
Uncontrolled Hypertension, Cardiovascular Risk Factor
Interventions
Internet-based Positive Psychological Intervention
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 4, 2019 · Synced Sep 1, 2026, 7:43 PM EDT
Completed Not applicable Interventional Results available

Self-Directed Positive Psychology Intervention for Newly Diagnosed Multiple Sclerosis

NCT06891937
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Positive psychology
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Sep 1, 2026, 7:43 PM EDT
Not listed Not applicable Interventional

Developing a Positive Psychology Intervention to Promote Health Behaviors in Metabolic Syndrome: RCT

NCT04039165
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
PP-MI Intervention
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 100 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Revere, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 18, 2022 · Synced Sep 1, 2026, 7:43 PM EDT
Completed Not applicable Interventional Results available

Researching Emotions And Cardiac Health: Phase III

NCT03220204
View directory record Official record
Conditions
Congestive Heart Failure, Emotions, Patient Compliance
Interventions
PP-based health behavior intervention, MI-based educational control condition
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 29, 2021 · Synced Sep 1, 2026, 7:43 PM EDT
Completed Not applicable Interventional

Boosting Emotions & Happiness in Outpatients Living With Diabetes: Phase I

NCT03001999
View directory record Official record
Conditions
Type 2 Diabetes, Emotions, Patient Compliance
Interventions
PP-MI health behavior intervention
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 4, 2018 · Synced Sep 1, 2026, 7:43 PM EDT
Completed Not applicable Interventional

Piloting Text Messages to Promote Positive Affect and Physical Activity

NCT04077229
View directory record Official record
Conditions
Acute Coronary Syndrome
Interventions
Intervention arm: Text Message Intervention
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 20, 2020 · Synced Sep 1, 2026, 7:43 PM EDT
Completed Not applicable Interventional

Mobile Weight Loss Intervention for Adolescent and Young Adult Cancer Survivors

NCT06171945
View directory record Official record
Conditions
Cancer, Physical Activity, Cancer Survivorship, Mental Health, Obesity
Interventions
AYA Connect intervention, Positive Psychology (PP) intervention, Positive Psychology Plus (PP+) intervention
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
18 Years to 39 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 26, 2025 · Synced Sep 1, 2026, 7:43 PM EDT
Recruiting Not applicable Interventional

Positive Emotions Following Acute Cardiac Events

NCT05412862
View directory record Official record
Conditions
Acute Coronary Syndrome, Physical Inactivity
Interventions
Positive Psychology + Motivational Interviewing
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 95 Years
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 19, 2026 · Synced Sep 1, 2026, 7:43 PM EDT
Completed Phase 1 Interventional

Text Messaging to Increase Activity in Midlife

NCT04849052
View directory record Official record
Conditions
Middle Aged
Interventions
MASTERY, Attentional Control
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
45 Years to 64 Years
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 22, 2025 · Synced Sep 1, 2026, 7:43 PM EDT
Completed Not applicable Interventional

A Tailored Program to Promote Well-being and Physical Activity in Mid-life Adults With Low Physical Activity

NCT04745182
View directory record Official record
Conditions
Middle Aged, Exercise
Interventions
MASTERY
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
45 Years to 64 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 8, 2021 · Synced Sep 1, 2026, 7:43 PM EDT
Recruiting Not applicable Interventional

Boosting Emotional Well-being and Happiness in Outpatients Living With Diabetes

NCT05420051
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
Positive Psychology + Motivational Interviewing, Motivational Interviewing
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Sep 1, 2026, 7:43 PM EDT
Completed Not applicable Interventional Results available

Researching Emotions And Cardiac Health (REACH): Phase II

NCT02938052
View directory record Official record
Conditions
Congestive Heart Failure, Emotions, Patient Compliance
Interventions
PP-based health behavior intervention
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 31, 2021 · Synced Sep 1, 2026, 7:43 PM EDT
Not listed Not applicable Interventional

Positive Psychology Intervention for Spanish-speaking Hispanic/Latino Adults at Risk for Cardiovascular Disease

NCT03221114
View directory record Official record
Conditions
Uncontrolled Hypertension, Cardiovascular Risk Factor
Interventions
Positive Psychological Intervention
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years and older
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 19, 2019 · Synced Sep 1, 2026, 7:43 PM EDT