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ClinicalTrials.gov public records Last synced Oct 31, 2026, 5:54 PM EDT

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Showing 1–24 of 68 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Positive Psychology Exercises Clear all
Completed Not applicable Interventional Results available

A Proof-of-Concept Trial of a Positive Psychology Intervention for Allogeneic Stem Cell Transplant Patients

NCT03654404
View directory record Official record
Conditions
Hematologic Malignancy, Hematopoietic/Lymphoid Cancer, Blood Cancer
Interventions
Positive Psychology Intervention
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 90 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Oct 31, 2026, 5:54 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Behavioral Medicine Intervention With Depressed Patients in a Community Health Center Setting

NCT01330420
View directory record Official record
Conditions
Depression
Interventions
Relaxation Response Resiliency Program for Depression
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
21 Years and older
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
2
States / cities
Charlestown, Massachusetts • Revere, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 21, 2017 · Synced Oct 31, 2026, 5:54 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility of a Mind-Body Intervention for Optimism

NCT07862478
View directory record Official record
Conditions
Emotional Well-being, Psychological Stress, Cardiovascular Risk
Interventions
Emotional Well-Being Writing, Chair-Assisted Squats, Slow-Paced Breathing
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
40 Years to 65 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 31, 2026, 5:54 PM EDT
Recruiting Not applicable Interventional

Testing the mHealth App Intervention for Nondaily Smokers "SiS4"

NCT06678243
View directory record Official record
Conditions
Smoking Cessation
Interventions
Smiling instead of Smoking, QuitGuide
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
1,600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 31, 2026, 5:54 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Exploring an Incubator to Decrease Stress in Farmers Occupational Stress and Depression in Beginning Kentucky Farmers

NCT04932018
View directory record Official record
Conditions
Occupational Stress, Depression
Interventions
Virtual Community of Support, Mentorship Incubator
Behavioral
Lead sponsor
Martha Biddle
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Nov 18, 2022 · Synced Oct 31, 2026, 5:54 PM EDT
Completed Not applicable Interventional

Managing Pain and Cognitions in Older Adults With Early Cognitive Decline and Chronic Pain

NCT05373745
View directory record Official record
Conditions
Chronic Pain, Mild Cognitive Impairment, Older Adults, Physical Activity
Interventions
Active Brains 1, Active Brains 2
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
60 Years and older
Enrollment
267 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 12, 2026 · Synced Oct 31, 2026, 5:54 PM EDT
Completed Not applicable Interventional

A Trial of a Positive Psychology Intervention for Older Adults (RESET)

NCT05451589
View directory record Official record
Conditions
Depressive Symptoms, Anxiety, Chronic Pain, Fatigue, Loneliness, Stress, Psychological
Interventions
RESET, Wellness Check Control
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
50 Years and older
Enrollment
457 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 31, 2026, 5:54 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Mental Health Curriculum Study

NCT04338256
View directory record Official record
Conditions
Mental Health Issue
Interventions
Wellness and Resilience for College and Beyond (Undergraduate College Course)
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 24 Years
Enrollment
295 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
5
States / cities
Greensburg, Pennsylvania • Pittsburgh, Pennsylvania • Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Apr 19, 2021 · Synced Oct 31, 2026, 5:54 PM EDT
Completed Not applicable Interventional Results available

A Psychological-behavioral Intervention to Increase Activity in Type 2 Diabetes

NCT03164538
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
Positive Psychology + Motivational Interviewing, Diabetes Education
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 21, 2021 · Synced Oct 31, 2026, 5:54 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

A Study of a Mental Fitness Intervention for Anesthesiology Resident Wellbeing and Self-Compassion

NCT07639827
View directory record Official record
Conditions
Wellness, Self Compassion, Burnout, Anxiety, Depression
Interventions
App-based bundled mental fitness intervention, App-based wellness module collection
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Oct 31, 2026, 5:54 PM EDT
Completed Not applicable Interventional Results available

Gaining Optimism After Weight Loss Surgery (GOALS) I

NCT04867902
View directory record Official record
Conditions
Bariatric Surgery
Interventions
Positive Psychology-Motivational Interviewing Intervention
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 2, 2026 · Synced Oct 31, 2026, 5:54 PM EDT
Completed Not applicable Interventional Results available

Positive Psychology for Acute Coronary Syndrome Patients

NCT03122184
View directory record Official record
Conditions
ACS - Acute Coronary Syndrome
Interventions
Positive Psychology + Motivational Interviewing, Motivational Interviewing Health Education
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 14, 2020 · Synced Oct 31, 2026, 5:54 PM EDT
Completed Not applicable Interventional

Sleep After Adolescent Concussion

NCT03781076
View directory record Official record
Conditions
Brain Concussion
Interventions
Sleep Intervention
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
12 Years to 18 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 28, 2020 · Synced Oct 31, 2026, 5:54 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Text- and Audio-based Intervention to Promote Physical Activity in Midlife

NCT06172933
View directory record Official record
Conditions
Middle Aged
Interventions
Move with Meaning
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
45 Years to 64 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 31, 2026, 5:54 PM EDT
Recruiting Not applicable Interventional

Promoting Well-being and Health in Heart Failure

NCT04829617
View directory record Official record
Conditions
Heart Failure, Heart Failure NYHA Class I, Heart Failure NYHA Class II, Heart Failure NYHA Class III
Interventions
PP-MI Intervention, MI-alone Intervention
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Oct 31, 2026, 5:54 PM EDT
Completed Not applicable Interventional

Well-being in IBS: Strengths and Happiness (WISH)

NCT05289089
View directory record Official record
Conditions
Irritable Bowel Syndrome
Interventions
Positive Psychology Intervention
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 22, 2025 · Synced Oct 31, 2026, 5:54 PM EDT
Completed Not applicable Interventional Results available

Researching Emotions And Cardiac Health: Phase III

NCT03220204
View directory record Official record
Conditions
Congestive Heart Failure, Emotions, Patient Compliance
Interventions
PP-based health behavior intervention, MI-based educational control condition
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 30, 2021 · Synced Oct 31, 2026, 5:54 PM EDT
Completed Not applicable Interventional Results available

Self-Directed Positive Psychology Intervention for Newly Diagnosed Multiple Sclerosis

NCT06891937
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Positive psychology
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 22, 2026 · Synced Oct 31, 2026, 5:54 PM EDT
Completed Phase 1 Interventional Results available

Text Messaging to Increase Activity in Midlife

NCT04849052
View directory record Official record
Conditions
Middle Aged
Interventions
MASTERY, Attentional Control
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
45 Years to 64 Years
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 31, 2026, 5:54 PM EDT
Completed Not applicable Interventional Results available

Researching Emotions And Cardiac Health (REACH): Phase II

NCT02938052
View directory record Official record
Conditions
Congestive Heart Failure, Emotions, Patient Compliance
Interventions
PP-based health behavior intervention
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 1, 2021 · Synced Oct 31, 2026, 5:54 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Two-Session Couples Class to Improve Relationship Health

NCT05026372
View directory record Official record
Conditions
Stress
Interventions
Mindfulness Compassion (MC), Mindfulness Gratitude (MG), Mindfulness Value-Based Living (MV)
Behavioral
Lead sponsor
Sam Houston State University
Other
Eligibility
18 Years and older
Enrollment
126 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Huntsville, Texas
Source: ClinicalTrials.gov public record
Updated Oct 24, 2023 · Synced Oct 31, 2026, 5:54 PM EDT
Completed Not applicable Interventional Results available

Developing a Positive Psychology Intervention to Promote Health Behaviors in Metabolic Syndrome: Proof-of Concept Trial

NCT03473886
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
Intervention arm: PP-MI
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 100 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 12, 2020 · Synced Oct 31, 2026, 5:54 PM EDT
Recruiting Not applicable Interventional

Healthy Aging as Black Adults, In It Together: a Comparative Effectiveness Study of Chronic Pain and Cognitive Decline

NCT06246929
View directory record Official record
Conditions
Chronic Pain, Physical Activity, Older Adults, Mild Cognitive Impairment
Interventions
MBCT+w, ALED
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
50 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Oct 31, 2026, 5:54 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Mobile-Web Emotion Self-management Tool

NCT02346591
View directory record Official record
Conditions
Stress, Depression
Interventions
Jauntly, Online stress management information
Behavioral
Lead sponsor
Oregon Center for Applied Science, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
298 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Jan 27, 2015 · Synced Oct 31, 2026, 5:54 PM EDT