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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Positive STEPS Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Problem-Solving Therapy for Cancer Caregivers in Outpatient Palliative Care

NCT04867122
View directory record Official record
Conditions
Depression, Anxiety, Palliative Care, Caregivers, Cancer
Interventions
Problem-Solving Therapy, Attention-matched Control, In-depth interviews
Behavioral · Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
532 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
3
States / cities
Columbia, Missouri • St Louis, Missouri • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Sep 3, 2026, 9:43 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

The Multimedia HIV/STI Prevention for Drug-Involved Female Offenders

NCT01784809
View directory record Official record
Conditions
HIV, Sexually Transmitted Infections
Interventions
Multimedia WORTH, Traditional WORTH, Wellness Promotion
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older · Female only
Enrollment
306 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 26, 2014 · Synced Sep 3, 2026, 9:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Promoting Community Conversations About Research to End Native Youth Suicide in Rural Alaska

NCT03661255
View directory record Official record
Conditions
Suicide
Interventions
PC CARES
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
15 Years and older
Enrollment
1,427 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 3, 2026, 9:43 AM EDT
Completed Not applicable Interventional

A Video Intervention to Decrease Patient Fear of Colonoscopy After a Positive Fecal Immunochemical Test

NCT05458986
View directory record Official record
Conditions
Colorectal Carcinoma
Interventions
Media Intervention, Best Practice, Questionnaire Administration
Other
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
45 Years to 75 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 29, 2024 · Synced Sep 3, 2026, 9:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

We The Village Family Support Study

NCT04250077
View directory record Official record
Conditions
Community Reinforcement And Family Training, Family Health, Substance-Related Disorders
Interventions
Community Reinforcement And Family Training (CRAFT), We The Village Peer Community Forum
Behavioral
Lead sponsor
We The Village, Inc.
Other
Eligibility
19 Years and older
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Sep 3, 2026, 9:43 AM EDT
Active, not recruiting Phase 2 Interventional

A Study of Chemotherapy and Radiation Therapy Compared to Chemotherapy and Radiation Therapy Plus MEDI4736 (Durvalumab) Immunotherapy for Bladder Cancer Which Has Spread to the Lymph Nodes, INSPIRE Trial

NCT04216290
View directory record Official record
Conditions
Bladder Urothelial Carcinoma, Stage III Bladder Cancer AJCC v8
Interventions
Biopsy of Bladder, Biospecimen Collection, Cisplatin, Computed Tomography, Cystoscopy, Durvalumab, Fluorouracil, Gemcitabine Hydrochloride, Magnetic Resonance Imaging, Mitomycin, Patient Observation, Radiation Therapy
Procedure · Drug · Biological + 2 more
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
216
States / cities
Anchorage, Alaska • Fort Smith, Arkansas • Hot Springs, Arkansas + 153 more
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 3, 2026, 9:43 AM EDT
Completed Phase 1 Interventional

A Study of RO7293583 in Participants With Unresectable Metastatic Tyrosinase Related Protein 1 (TYRP1)-Positive Melanomas

NCT04551352
View directory record Official record
Conditions
Cutaneous Melanoma, Uveal Melanoma, Mucosal Melanoma
Interventions
RO7293583, Tocilizumab, Obinutuzumab, Adalimumab
Drug
Lead sponsor
Hoffmann-La Roche
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
4
States / cities
Boston, Massachusetts • New York, New York • Philadelphia, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 2, 2022 · Synced Sep 3, 2026, 9:43 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Online HIV Prevention for Young Male Couples

NCT03284541
View directory record Official record
Conditions
Hiv, Chlamydia, Gonorrhea
Interventions
2GETHER, Existing Public Health Practice
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Male only
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 27, 2023 · Synced Sep 3, 2026, 9:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Three Instructional Interventions for Prehospital Cervical Spinal Immobilization by Laypeople

NCT05359575
View directory record Official record
Conditions
Cervical Vertebra Injury, Cervical Vertebra Fracture
Interventions
Audio kit, Instructional flashcard (version 1), In-person training, Instructional flashcard (version 2)
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
265 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 26, 2022 · Synced Sep 3, 2026, 9:43 AM EDT
Completed Phase 1 Interventional

A Study of RO6958688 in Participants With Locally Advanced and/or Metastatic Carcinoembryonic Antigen Positive Solid Tumors

NCT02324257
View directory record Official record
Conditions
Solid Tumors
Interventions
RO6958688, Obinutuzumab, Tocilizumab
Drug
Lead sponsor
Hoffmann-La Roche
Industry
Eligibility
18 Years and older
Enrollment
149 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
9
States / cities
Los Angeles, California • Palo Alto, California • Santa Monica, California + 6 more
Source: ClinicalTrials.gov public record
Updated Apr 16, 2020 · Synced Sep 3, 2026, 9:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Family-based and Adolescent Residential Drug Treatment

NCT01737632
View directory record Official record
Conditions
Substance Use, Delinquency
Interventions
Multidimensional Family Therapy (MDFT), Adolescent Residential Treatment
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
13 Years to 17 Years
Enrollment
113 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2010
U.S. locations
2
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Nov 28, 2012 · Synced Sep 3, 2026, 9:43 AM EDT
Completed Not applicable Interventional

Effective Care Management of Depressed Diabetes Patients (The Positive Steps Study)

NCT01106885
View directory record Official record
Conditions
Diabetes, Depression
Interventions
Medication Care Management (MCM), Cognitive-Behavioral Therapy (CBT)
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
21 Years to 80 Years
Enrollment
339 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2011
U.S. locations
3
States / cities
Ann Arbor, Michigan • Grand Blanc, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 27, 2015 · Synced Sep 3, 2026, 9:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Strategies for Coping With Negative Thoughts

NCT05566691
View directory record Official record
Conditions
Depressive Symptoms, Anxiety, Negative Thinking
Interventions
Positive thinking, Positive thinking + Mood induction, Thought reevaluation, Thought reevaluation + Mood induction
Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
301 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 8, 2023 · Synced Sep 3, 2026, 9:43 AM EDT
Not yet recruiting Not applicable Interventional

Parent-Child Interaction Therapy (PCIT) for Children With Traumatic Brain Injury (TBI): A Stepped-Care Model

NCT06193382
View directory record Official record
Conditions
Traumatic Brain Injury, Disruptive Behavior
Interventions
PCIT
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
2 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Sep 3, 2026, 9:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Impact of Combined Behavioral Interventions on Cognitive Outcomes in MCI

NCT02864069
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
Walking Intervention, Cognitive Training Intervention, Combined Intervention
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
60 Years to 80 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jan 17, 2020 · Synced Sep 3, 2026, 9:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Selah Trial of Stress Interventions for Clergy: Mindfulness Based Stress Reduction, Daily Examen, and Stress Inoculation

NCT04625777
View directory record Official record
Conditions
Occupational Stress
Interventions
Mindfulness Based Stress Reduction, Daily Examen spiritual practice, Stress inoculation combination
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
390 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 21, 2022 · Synced Sep 3, 2026, 9:43 AM EDT
Completed Not applicable Interventional Results available

Evaluating Digital Micro-Interventions to Reduce Distress and Increase Wellbeing in Breast Cancer Survivors

NCT07160439
View directory record Official record
Conditions
Mental Health Issue, Breast Cancer
Interventions
Digital Micro-Interventions
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Sep 3, 2026, 9:43 AM EDT
Terminated Not applicable Interventional

Stress Index to Individualize Mechanical Ventilation in ARDS

NCT02871102
View directory record Official record
Conditions
Acute Respiratory Distress Syndrome
Interventions
Recruitment Maneuver with PEEP and Tidal Volume Optimization
Procedure
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 6, 2018 · Synced Sep 3, 2026, 9:43 AM EDT
Completed Not applicable Interventional

Exploring Beliefs and Behaviors About Weight Loss in Couples

NCT01777711
View directory record Official record
Conditions
Obesity
Interventions
Mental Contrasting- Individual, Mental Contrasting- Couple
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 25, 2014 · Synced Sep 3, 2026, 9:43 AM EDT
Not listed Not applicable Interventional

Effect of Transpulmonary Pressure Guided Ventilation on Intraoperative Right Heart Function

NCT05709041
View directory record Official record
Conditions
Obesity, Surgery, Anesthesia, Echocardiography, Transesophageal, Mechanical Ventilation
Interventions
Individualized lung-protective ventilation, Standard lung-protective ventilation
Other
Lead sponsor
University of Vermont Medical Center
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Jan 31, 2023 · Synced Sep 3, 2026, 9:43 AM EDT
Completed Not applicable Interventional

Improving Thinking in Everyday Life After Covid-19

NCT04644172
View directory record Official record
Conditions
Covid-19, Cognitive Impairment
Interventions
Speed of Processing Training, Instrumental Activities of Daily Living Shaping, Transfer Package from CI Therapy, Usual Care
Behavioral · Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 27, 2024 · Synced Sep 3, 2026, 9:43 AM EDT
Completed Not applicable Interventional Results available

Positive Psychology for Chronic Pain Self-management

NCT04321239
View directory record Official record
Conditions
Chronic Pain
Interventions
Positive STEPS
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
60 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 31, 2021 · Synced Sep 3, 2026, 9:43 AM EDT
Completed Not applicable Interventional Results available

Enhancing Quality Interventions Promoting Healthy Sexuality

NCT01818791
View directory record Official record
Conditions
Pregnancy in Adolescence, HIV
Interventions
Making Proud Choices, Making Proud Choices AND Getting To Outcomes
Behavioral
Lead sponsor
RAND
Other
Eligibility
10 Years to 14 Years
Enrollment
909 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2020
U.S. locations
4
States / cities
Auburn, Alabama • Huntsville, Alabama • Montgomery, Alabama + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Sep 3, 2026, 9:43 AM EDT
Completed Not applicable Interventional Results available

Improving Outcomes for Low-Income Mothers With Depression

NCT03221556
View directory record Official record
Conditions
Post Partum Depression
Interventions
Engagement-Focused Care Coordination (EFCC), Problem Solving Education (PSE)
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
231 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 3, 2026, 9:43 AM EDT