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ClinicalTrials.gov public records Last synced Oct 30, 2026, 8:41 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 937–960 of 1,719 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Positive control Clear all
Completed Not applicable Interventional Results available

Developing a Low-Intensity Primary Care Intervention for Anxiety Disorders (AIM-PC)

NCT02579915
View directory record Official record
Conditions
Anxiety Disorders
Interventions
FaceAnxiety, Symptom Tracking
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Pawtucket, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 7, 2020 · Synced Oct 30, 2026, 8:41 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Deflated and Inflated Cuff Endotracheal Extubations

NCT06990308
View directory record Official record
Conditions
Anesthesia Airway Management, Respiratory Complications
Interventions
Inflated Cuff Extubation, Deflated Cuff Extubation
Procedure
Lead sponsor
Naval Medical Center Camp Lejeune
Federal
Eligibility
18 Years to 50 Years
Enrollment
88 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Marine Corps Base Camp Lejeune, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 16, 2025 · Synced Oct 30, 2026, 8:41 PM EDT
Completed Not applicable Interventional Results available

A Positive Psychology Intervention for Patients With Multiple Sclerosis

NCT03637699
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Positive Psychology
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 16, 2021 · Synced Oct 30, 2026, 8:41 PM EDT
Completed No phase listed Observational

Immune Profiles in CF Fungal Infection

NCT04476758
View directory record Official record
Conditions
Cystic Fibrosis, Fungal Infection, Allergic Bronchopulmonary Aspergillosis
Interventions
Not listed
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
8 Years to 25 Years
Enrollment
24 participants
Timeline
2021 – 2023
U.S. locations
1
States / cities
Highlands Ranch, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 18, 2024 · Synced Oct 30, 2026, 8:41 PM EDT
Completed Not applicable Interventional

ARDSnet Protocol vs. Open Lung Approach in ARDS

NCT00431158
View directory record Official record
Conditions
Respiratory Distress Syndrome, Adult
Interventions
Different Mechanical Ventilation Protocols
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
224 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 18, 2014 · Synced Oct 30, 2026, 8:41 PM EDT
Completed Not applicable Interventional

Protective Ventilation With High Versus Low PEEP During One-lung Ventilation for Thoracic Surgery

NCT02963025
View directory record Official record
Conditions
One-Lung Ventilation
Interventions
PEEP level, Use of recruitment maneuvers
Procedure
Lead sponsor
Technische Universität Dresden
Other
Eligibility
18 Years and older
Enrollment
2,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
3
States / cities
Boston, Massachusetts • New York, New York • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 26, 2025 · Synced Oct 30, 2026, 8:41 PM EDT
Not listed Not applicable Interventional

Examining Effects of Domain Specific Episodic Future Thinking on Cannabis Use

NCT05324813
View directory record Official record
Conditions
Marijuana Use, Marijuana Dependence, Tobacco Use, Alcohol Use, Unspecified
Interventions
Domain-Specific Episodic Future Thinking
Behavioral
Lead sponsor
Michael Sofis
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Sudbury, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 12, 2022 · Synced Oct 30, 2026, 8:41 PM EDT
Terminated Phase 2 Interventional Results available

Study of the Safety, Tolerability and Efficacy of NP-101 in Treating High Risk Participants Who Are Covid-19 Positive.

NCT05785390
View directory record Official record
Conditions
COVID-19
Interventions
NP-101, Placebo
Drug · Other
Lead sponsor
Novatek Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
4
States / cities
Miami, Florida • Berwyn, Illinois • Houston, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Oct 30, 2026, 8:41 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Opaganib, a Sphingosine Kinase-2 (SK2) Inhibitor in COVID-19 Pneumonia

NCT04467840
View directory record Official record
Conditions
COVID-19, Lung Infection
Interventions
Opaganib, Placebo
Drug
Lead sponsor
RedHill Biopharma Limited
Industry
Eligibility
18 Years to 80 Years
Enrollment
475 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 31, 2025 · Synced Oct 30, 2026, 8:41 PM EDT
Completed Phase 2 Interventional Results available

Diarrhea Prevention and Prophylaxis With Crofelemer in HER2 Positive Breast Cancer Patients

NCT02910219
View directory record Official record
Conditions
Breast Cancer
Interventions
Crofelemer
Drug
Lead sponsor
Sandra Swain
Other
Eligibility
18 Years and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
4
States / cities
Washington D.C., District of Columbia • Baltimore, Maryland • Hackensack, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 24, 2022 · Synced Oct 30, 2026, 8:41 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Engaging Motivation for the Prevention of Weight Regain

NCT01169428
View directory record Official record
Conditions
Obesity
Interventions
Mindfulness Based Weight Loss Maintenance (MBWLM), Behavioral: Standard Behavioral Weight-Loss Maintenence
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
2
States / cities
Durham, North Carolina • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 14, 2013 · Synced Oct 30, 2026, 8:41 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

A Neuroimaging Study of Open-label Placebo in Depressed Adolescents

NCT04201106
View directory record Official record
Conditions
Depression
Interventions
Open Label Placebo with Rationale, Open Label Placebo without Rationale
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
13 Years to 18 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Oct 30, 2026, 8:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Improvement of Dry Mouth Sufferers After Using an Experimental Dry Mouth Rinse Compared to a Water Control

NCT04189081
View directory record Official record
Conditions
Dry Mouth
Interventions
dry mouth rinse, Water Control
Device · Other
Lead sponsor
Procter and Gamble
Industry
Eligibility
18 Years and older
Enrollment
137 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated May 28, 2021 · Synced Oct 30, 2026, 8:41 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

The Effects AZD8529 on Ketamine-induced Impairment of Working Memory in Healthy Volunteers

NCT00985933
View directory record Official record
Conditions
Healthy, Memory Impairment
Interventions
AZD8529, Placebo to match AZD8529
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
21 Years to 45 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 4, 2011 · Synced Oct 30, 2026, 8:41 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Engaging Church Health Ministries to Decrease Coronavirus Disease-19 Vaccine Hesitancy in Underserved Populations

NCT05541393
View directory record Official record
Conditions
COVID-19
Interventions
Active Intervention Group
Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Apr 27, 2023 · Synced Oct 30, 2026, 8:41 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Multiple-Dose Study of Effect of Bardoxolone Methyl on QT/QTC Interval Volunteers

NCT01689116
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Bardoxolone Methyl 20mg, Bardoxolone Methyl 80mg, Bardoxolone Methyl Placebo, Moxifloxacin 400mg, Moxifloxacin Placebo
Drug
Lead sponsor
Biogen
Industry
Eligibility
18 Years to 50 Years
Enrollment
179 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
West Bend, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 29, 2025 · Synced Oct 30, 2026, 8:41 PM EDT
Active, not recruiting Phase 3 Interventional

A Study Evaluating the Efficacy and Safety of Giredestrant Combined With Palbociclib Compared With Letrozole Combined With Palbociclib in Participants With Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer (persevERA Breast Cancer)

NCT04546009
View directory record Official record
Conditions
Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer
Interventions
Giredestrant, Giredestrant-matched Placebo, Letrozole, Letrozole-matched Placebo, Palbociclib, LHRH Agonist
Drug
Lead sponsor
Hoffmann-La Roche
Industry
Eligibility
18 Years and older
Enrollment
992 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
37
States / cities
Fountain Valley, California • Long Beach, California • San Leandro, California + 32 more
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 30, 2026, 8:41 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

External Body Pressure in Heart Failure With Preserved Ejection Fraction

NCT05764564
View directory record Official record
Conditions
Heart Failure, Diastolic
Interventions
Positive or negative pressure
Diagnostic Test
Lead sponsor
Duke University
Other
Eligibility
30 Years and older
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 30, 2026, 8:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Ridge Preservation Comparing a PTFE Nonresorbable Membrane to a Collagen Membrane

NCT01900964
View directory record Official record
Conditions
Clinical Efficacy
Interventions
PTFE membrane, Collagen membrane
Procedure
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Louisvile, Kentucky
Source: ClinicalTrials.gov public record
Updated Dec 8, 2016 · Synced Oct 30, 2026, 8:41 PM EDT
Active, not recruiting Phase 3 Interventional

Allogeneic ABCB5-positive Dermal Mesenchymal Stromal Cells for Treatment of Epidermolysis Bullosa (Phase III)

NCT05838092
View directory record Official record
Conditions
Epidermolysis Bullosa
Interventions
allo-APZ2-OTS, Placebo
Drug
Lead sponsor
RHEACELL GmbH & Co. KG
Industry
Eligibility
6 Months and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
Aurora, Colorado • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Oct 30, 2026, 8:41 PM EDT
Not yet recruiting Not applicable Interventional

A Randomized Controlled Trial of a Smartphone Delivered Treatment for Suicidal Thoughts and Behavior

NCT06686901
View directory record Official record
Conditions
Suicidal Ideation, Suicide Attempt
Interventions
Smartphone-delivered Therapeutic Evaluative Conditioning for Suicide (TEC-S), Smartphone-delivered inactive Therapeutic Evaluative Conditioning
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 30, 2026, 8:41 PM EDT
Recruiting Not applicable Interventional

Implementation of TBI-RECOVER in Substance Use Treatment

NCT07215221
View directory record Official record
Conditions
Traumatic Brain Injury, Substance Use Disorder (SUD)
Interventions
TBI-RECOVER, Control
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Oct 30, 2026, 8:41 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Study to Investigate the Effects of Single Intravenous Doses of Difelikefalin (CR845) on the QTc Interval in Healthy Subjects

NCT04019574
View directory record Official record
Conditions
Healthy
Interventions
CR845 0.5 mcg/kg IV, CR845 3 mcg/kg IV, Moxifloxacin 400 mg Oral Tablet, Placebo
Drug · Other
Lead sponsor
Cara Therapeutics, Inc.
Industry
Eligibility
18 Years to 45 Years
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Feb 21, 2020 · Synced Oct 30, 2026, 8:41 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Evaluation of the Allergenicity of AMPHADASE INJECTION (Hyaluronidase Injection USP)

NCT01689363
View directory record Official record
Conditions
Allergic Skin Reaction
Interventions
Hyaluronidase, Histamine, Saline
Drug
Lead sponsor
Amphastar Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
253 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
5
States / cities
Eugene, Oregon • Lake Oswego, Oregon • Portland, Oregon + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 20, 2017 · Synced Oct 30, 2026, 8:41 PM EDT