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ClinicalTrials.gov public records Last synced Oct 31, 2026, 1:40 PM EDT

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Showing 1081–1104 of 1,719 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Positive control Clear all
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The Families and Middle School Success Project

NCT05400564
View directory record Official record
Conditions
Parenting, Parent-Child Relations, Self-regulation, Problem Behavior in School, School Adjustment, Depression
Interventions
Family Check-Up
Behavioral
Lead sponsor
University of Oregon
Other
Eligibility
Not listed
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 15, 2024 · Synced Oct 31, 2026, 1:40 PM EDT
Completed Phase 2 Interventional Results available

AZD6244 in Combination With Docetaxel Versus Docetaxel Alone in KRAS Mutation Positive NSCLC Patients

NCT00890825
View directory record Official record
Conditions
Non Small Cell Lung Cancer
Interventions
AZD6244, docetaxel, Placebo
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years to 130 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2016
U.S. locations
4
States / cities
Los Angeles, California • Aurora, Colorado • Boston, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 20, 2018 · Synced Oct 31, 2026, 1:40 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Improving Quality by Maintaining Accurate Problems in the EHR

NCT02596087
View directory record Official record
Conditions
Asthma, Atrial Fibrillation, Chronic Obstructive Pulmonary Disease, Coronary Artery Disease, Congestive Heart Failure, Hyperlipidemia, Hypertension, Myocardial Infarction, Sickle Cell Disease, Sleep Apnea, Smoking, Stroke, Tuberculosis
Interventions
Problem List Suggestion
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
2,386 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2016
U.S. locations
4
States / cities
Boston, Massachusetts • Portland, Oregon • Camp Hill, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 8, 2023 · Synced Oct 31, 2026, 1:40 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Study to Determine the Anti-plaque Efficacy of Commerical Toothpastes and an Oral Rinse

NCT01024738
View directory record Official record
Conditions
Dental Plaque
Interventions
Fluoride, Triclosan, fluoride, Chlorhexidine Gluconate
Drug
Lead sponsor
Colgate Palmolive
Industry
Eligibility
18 Years to 65 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
1
States / cities
Paramus, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 3, 2009 · Synced Oct 31, 2026, 1:40 PM EDT
Completed Not applicable Interventional Results available

Effects of Continuous Positive Airway Pressure (CPAP) Treatment on Glucose Control in Patients With Type 2 Diabetes

NCT01136785
View directory record Official record
Conditions
Obstructive Sleep Apnea, Type 2 Diabetes
Interventions
active CPAP Therapy, sham CPAP therapy
Device
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 10, 2017 · Synced Oct 31, 2026, 1:40 PM EDT
Recruiting Not applicable Interventional

Continued Pressure for Alveolar Protection (CPAP Trial)

NCT07417111
View directory record Official record
Conditions
Bronchopulmonary Dysplasia (BPD)
Interventions
CPAP, Nasal Cannula
Device
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 31 Weeks
Enrollment
860 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
15
States / cities
Birmingham, Alabama • Palo Alto, California • San Diego, California + 12 more
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Oct 31, 2026, 1:40 PM EDT
Completed Not applicable Interventional Results available

Powered Seating Function Usage Among Veterans - Compliance and Coaching

NCT00839098
View directory record Official record
Conditions
Use of Power Wheelchairs and Power Seat Functions
Interventions
Instruction Group: Power seat function usage instruction- verbal and written instruction, Instruction and Virtual Coach Group: Power seat function usage instruction- verbal, written, and virtual coach
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 4, 2016 · Synced Oct 31, 2026, 1:40 PM EDT
Completed Not applicable Interventional Results available

Targeting Obesity to Optimize Health in Cardiac Rehab (TOPCARE)

NCT03423238
View directory record Official record
Conditions
Obesity, Weight Loss, CHD - Coronary Heart Disease
Interventions
Exercise, Health Education, Exercise Compliance, Calorie-Restricted Diet, Behavioral Modification, Weight-Loss Compliance, Dietary Counseling
Other · Behavioral · Dietary Supplement
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
40 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 23, 2021 · Synced Oct 31, 2026, 1:40 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A SMART Evaluation of an Adaptive Web-based AUD Treatment for Service Members and Their Partners

NCT05619185
View directory record Official record
Conditions
Alcohol Abuse, Alcohol Use Disorder, Alcohol Drinking, Relations, Interpersonal, Military Family
Interventions
CRAFT Web-Based Intervention, Phone-Based CRAFT, CRAFT Workbook, Gottman Self-Guided Resources
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
744 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Oct 19, 2026 · Synced Oct 31, 2026, 1:40 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Phase 1 Study to Evaluate Effects of Sapropterin Dihydrochloride on QTc Intervals in Healthy Adult Subjects

NCT00789568
View directory record Official record
Conditions
Phenylketonuria
Interventions
sapropterin dihydrochloride, Moxifloxacin, Moxifloxacin placebo
Drug
Lead sponsor
BioMarin Pharmaceutical
Industry
Eligibility
18 Years to 50 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Fargo, North Dakota
Source: ClinicalTrials.gov public record
Updated Jul 23, 2021 · Synced Oct 31, 2026, 1:40 PM EDT
Completed Not applicable Interventional

Enhancing Corticospinal Excitability to Improve Functional Recovery

NCT03237091
View directory record Official record
Conditions
Spinal Cord Injuries, Tetraplegia
Interventions
bihemispheric transcranial pulsed current stimulation (tPCS), unihemispheric transcranial pulsed current stimulation (tPCS), bihemispheric transcranial direct current stimulation (tDCS), unihemispheric transcranial direct current stimulation (tDCS), sham-control
Other
Lead sponsor
Shepherd Center, Atlanta GA
Other
Eligibility
18 Years to 65 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 8, 2019 · Synced Oct 31, 2026, 1:40 PM EDT
Not listed Not applicable Interventional

Extralevator Versus Standard Abdominoperineal Resection For Rectal Adenocarcinoma

NCT01702116
View directory record Official record
Conditions
Rectal Adenocarcinoma
Interventions
extralevator APR, APR
Procedure
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
3
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Apr 25, 2013 · Synced Oct 31, 2026, 1:40 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

An Exosomal miRNA-based Liquid Biopsy for ICC Detection

NCT07225452
View directory record Official record
Conditions
Intrahepatic Cholangiocarcinoma (Icc)
Interventions
Small RNA sequencing, LUMIC assay
Diagnostic Test
Lead sponsor
City of Hope Medical Center
Other
Eligibility
18 Years and older
Enrollment
535 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Duarte, California
Source: ClinicalTrials.gov public record
Updated Mar 13, 2026 · Synced Oct 31, 2026, 1:40 PM EDT
Completed Phase 3 Interventional Results available

Everolimus in Combination With Exemestane in the Treatment of Postmenopausal Women With Estrogen Receptor Positive Locally Advanced or Metastatic Breast Cancer Who Are Refractory to Letrozole or Anastrozole

NCT00863655
View directory record Official record
Conditions
Breast Cancer
Interventions
Everolimus, Exemestane, Everolimus Placebo
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years and older · Female only
Enrollment
724 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
63
States / cities
Chandler, Arizona • Fayetteville, Arkansas • Anaheim, California + 54 more
Source: ClinicalTrials.gov public record
Updated May 2, 2017 · Synced Oct 31, 2026, 1:40 PM EDT
Withdrawn Not applicable Interventional

Proteus Sustained Behavior Change Study

NCT01503008
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
Proteus Sustained Behavior Change system, Regularly prescribed diabetes medicines (metformin, sulfonylureas, thiazolidinediones, DPP-IV inhibitors, alpha-glucosidase inhibitors)
Device · Drug
Lead sponsor
Proteus Digital Health, Inc.
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
2
States / cities
Chicago, Illinois • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 5, 2013 · Synced Oct 31, 2026, 1:40 PM EDT
Completed Not applicable Interventional

Psychologically Informed Education Intervention for Adolescents With Atraumatic Lower-Extremity Injuries

NCT05701618
View directory record Official record
Conditions
Leg Injury
Interventions
Psychologically Informed Education Video Series, Anatomy and biomedical education videos
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
12 Years to 18 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Oct 31, 2026, 1:40 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Bleeding-Model Clinical Study

NCT05916508
View directory record Official record
Conditions
Gingivitis
Interventions
0.454% stannous fluoride, 0.76% sodium monofluorophosphate, 0.454% stannous fluoride AM and 0.76% sodium monofluorophosphate PM
Drug
Lead sponsor
Procter and Gamble
Industry
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Jun 23, 2023 · Synced Oct 31, 2026, 1:40 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Expressive Writing Intervention Study

NCT05782868
View directory record Official record
Conditions
Distress, Emotional
Interventions
Expressive writing in response to vignette, Expressive writing about events of the day, Letter of Gratitude
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
117 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 31, 2026, 1:40 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Juntos: A Pilot Test of a Dating Violence Intervention for Latine Families

NCT06672679
View directory record Official record
Conditions
Intimate Partner Violence (IPV), Cultural Diversity, Prevention, Parent
Interventions
Juntos, Resource guide
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
12 Years and older
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Oct 31, 2026, 1:40 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Keep Social Study for Young Adults

NCT07005817
View directory record Official record
Conditions
Social Isolation, Loneliness
Interventions
Experimental Health Communication, Simulated Social Media Platform Only
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 29 Years
Enrollment
1,900 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Oct 31, 2026, 1:40 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Student Wellness 2.0

NCT06804213
View directory record Official record
Conditions
Mental Health Issue
Interventions
Mobile health app with positive psychological activities
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
83 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
2
States / cities
Ann Arbor, Michigan • Port Chester, New York
Source: ClinicalTrials.gov public record
Updated Jul 3, 2025 · Synced Oct 31, 2026, 1:40 PM EDT
Completed Not applicable Interventional

Mild Intermittent Hypoxia and Its Multipronged Effect on Sleep Apnea

NCT03736382
View directory record Official record
Conditions
Obstructive Sleep Apnea, Spinal Cord Injuries
Interventions
Mild intermittent hypoxia, Sham protocol, Continuous positive airway pressure (CPAP)
Other
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 60 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
2
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 31, 2026, 1:40 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Development and Pilot Trial of an Intervention to Reduce Disclosure Recipients Negative Social Reactions and Victims Psychological Distress and Problem Drinking

NCT03488927
View directory record Official record
Conditions
Social Skills, Self-Criticism, Post-traumatic Stress Disorder, Depression, Alcohol Abuse, Drinking, College, Alcohol Drinking, Alcohol; Harmful Use, Social Stigma, Social Norms, Social Responsibility, Social Behavior, Empathy, Coping Skills, Coping Behavior
Interventions
Supporting Survivors and Self: An Intervention for Social Supports of Survivors of Partner Abuse and Sexual Aggression (SSS)
Behavioral
Lead sponsor
University of New Hampshire
Other
Eligibility
18 Years to 24 Years
Enrollment
1,268 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Durham, New Hampshire
Source: ClinicalTrials.gov public record
Updated Oct 19, 2020 · Synced Oct 31, 2026, 1:40 PM EDT
Completed Not applicable Interventional Results available

Enhancing Quality Interventions Promoting Healthy Sexuality

NCT01818791
View directory record Official record
Conditions
Pregnancy in Adolescence, HIV
Interventions
Making Proud Choices, Making Proud Choices AND Getting To Outcomes
Behavioral
Lead sponsor
RAND
Other
Eligibility
10 Years to 14 Years
Enrollment
909 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2020
U.S. locations
4
States / cities
Auburn, Alabama • Huntsville, Alabama • Montgomery, Alabama + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Oct 31, 2026, 1:40 PM EDT