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Showing 1–24 of 138 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Positive psychology Clear all
Completed No phase listed Observational Accepts healthy volunteers

Mental Health Curriculum Study

NCT04338256
View directory record Official record
Conditions
Mental Health Issue
Interventions
Wellness and Resilience for College and Beyond (Undergraduate College Course)
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 24 Years
Enrollment
295 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
5
States / cities
Greensburg, Pennsylvania • Pittsburgh, Pennsylvania • Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Apr 18, 2021 · Synced Sep 12, 2026, 4:34 AM EDT
Completed Not applicable Interventional

Well-being in IBS: Strengths and Happiness (WISH)

NCT05289089
View directory record Official record
Conditions
Irritable Bowel Syndrome
Interventions
Positive Psychology Intervention
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 21, 2025 · Synced Sep 12, 2026, 4:34 AM EDT
Recruiting Not applicable Interventional

VCOM Pain Free Research Collaborative

NCT06533345
View directory record Official record
Conditions
Chronic Pain
Interventions
Behavior Change Coaching, Nutrition, Autonomic Recalibration, Dry Needling, Osteopathic Manipulative Treatment, Counseling Psychology, Multiple Treatments
Behavioral · Other · Procedure
Lead sponsor
Edward Via Virginia College of Osteopathic Medicine
Other
Eligibility
21 Years to 80 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 19, 2026 · Synced Sep 12, 2026, 4:34 AM EDT
Completed Not applicable Interventional Results available

Effects of a Wellbeing Intervention on Inflammation Through Reward and Threat Processes

NCT06294145
View directory record Official record
Conditions
Low Positive Affect
Interventions
Savoring Intervention
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 25 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Sep 12, 2026, 4:34 AM EDT
Completed Phase 1 Interventional Results available

Text Messaging to Increase Activity in Midlife

NCT04849052
View directory record Official record
Conditions
Middle Aged
Interventions
MASTERY, Attentional Control
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
45 Years to 64 Years
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Sep 12, 2026, 4:34 AM EDT
Recruiting Not applicable Interventional

EMPoWER Study - Strengths-based Behavioral Intervention for Youth With Type 1 Diabetes

NCT06014879
View directory record Official record
Conditions
Type 1 Diabetes
Interventions
Type 1 Doing Well (T1DW) Program, Diabetes-Related Information and Resources Program
Behavioral · Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
10 Years to 99 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Sep 12, 2026, 4:34 AM EDT
Completed Not applicable Interventional Results available

A Positive Psychology Intervention for Patients With Multiple Sclerosis

NCT03637699
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Positive Psychology
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 15, 2021 · Synced Sep 12, 2026, 4:34 AM EDT
Completed Not applicable Interventional

Trial of a Positive Psychology Intervention in Major Depressive Disorder

NCT02004145
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Positive Psychology, Control Condition
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 18, 2016 · Synced Sep 12, 2026, 4:34 AM EDT
Completed Not applicable Interventional Results available

Mind-body Resiliency Intervention for Fear of Cancer Recurrence

NCT04876599
View directory record Official record
Conditions
Cancer, Coping Skills, Coping Behavior
Interventions
IN FOCUS, Usual Care
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
5
States / cities
Boston, Massachusetts • Concord, Massachusetts • Danvers, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 11, 2023 · Synced Sep 12, 2026, 4:34 AM EDT
Not yet recruiting Phase 2Phase 3 Interventional Accepts healthy volunteers

A Stepped Care Approach to Treating Tobacco Use in Rural Veterans

NCT04501016
View directory record Official record
Conditions
Tobacco Cessation
Interventions
Tailored behavioral counseling, Tobacco cessation pharmacotherapy
Behavioral · Drug
Lead sponsor
Iowa City Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 99 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Aug 5, 2020 · Synced Sep 12, 2026, 4:34 AM EDT
Recruiting Not applicable Interventional

Well-being in IBS: Strengths and Happiness (WISH) 2.0

NCT06866106
View directory record Official record
Conditions
Irritable Bowel Syndrome
Interventions
Positive Psychology (PP) Intervention, Educational Intervention
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 21, 2026 · Synced Sep 12, 2026, 4:34 AM EDT
Completed Not applicable Interventional Results available

Managing Pain and Cognitions in Older Adults With Mild Cognitive Impairment or Memory Related Problems and Chronic Pain

NCT04044183
View directory record Official record
Conditions
Chronic Pain, Mild Cognitive Impairment, Older Adults, Physical Activity
Interventions
Active Brains 1, Active Brains 2
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
60 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 19, 2023 · Synced Sep 12, 2026, 4:34 AM EDT
Completed Not applicable Interventional Results available

Check It! Positive Psychology Intervention to Improve Adherence in Adolescents With T1D

NCT02746627
View directory record Official record
Conditions
Type 1 Diabetes Mellitus
Interventions
Positive Affect, Education
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
13 Years to 17 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 12, 2019 · Synced Sep 12, 2026, 4:34 AM EDT
Terminated Not applicable Interventional Results available

Collaborative Care for Opioid Dependence And Pain Pilot Study

NCT04121546
View directory record Official record
Conditions
Opioid Dependence, Chronic Pain
Interventions
Telecare Intervention
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 29, 2024 · Synced Sep 12, 2026, 4:34 AM EDT
Completed Not applicable Interventional

Piloting Text Messages to Promote Positive Affect and Physical Activity

NCT04077229
View directory record Official record
Conditions
Acute Coronary Syndrome
Interventions
Intervention arm: Text Message Intervention
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 20, 2020 · Synced Sep 12, 2026, 4:34 AM EDT
Completed Not applicable Interventional

Positive Psychology Intervention to Improve Quality of Life in Stem Cell Transplant Survivors and Their Caregivers

NCT03525106
View directory record Official record
Conditions
Hematopoietic Cell Transplantation Recipient
Interventions
Booklet, Exercise Intervention, Quality-of-Life Assessment, Survey Administration, Telephone-Based Intervention
Behavioral · Other
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 3, 2020 · Synced Sep 12, 2026, 4:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Resilience Challenge: Fostering Emotional Resilience During a Time of National Stress

NCT06597032
View directory record Official record
Conditions
Stress, Positive Affect
Interventions
Resilience Challenge
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
11,659 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 6, 2025 · Synced Sep 12, 2026, 4:34 AM EDT
Active, not recruiting Not applicable Interventional

A Positive Psychology Based Intervention (PATH-C) for Caregivers of HSCT Survivors

NCT06153797
View directory record Official record
Conditions
Hematologic Malignancy, Caregiver
Interventions
PATH-C
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Sep 12, 2026, 4:34 AM EDT
Not listed Not applicable Interventional

Developing a Positive Psychology Intervention to Promote Health Behaviors in Metabolic Syndrome: RCT

NCT04039165
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
PP-MI Intervention
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 100 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Revere, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 18, 2022 · Synced Sep 12, 2026, 4:34 AM EDT
Completed Not applicable Interventional Results available

Gaining Optimism After Weight Loss Surgery (GOALS) II

NCT04868032
View directory record Official record
Conditions
Bariatric Surgery
Interventions
Positive Psychology-Motivational Interviewing, Physical Activity Education Control
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 26, 2026 · Synced Sep 12, 2026, 4:34 AM EDT
Recruiting Not applicable Interventional

Promoting Well-being and Health in Heart Failure

NCT04829617
View directory record Official record
Conditions
Heart Failure, Heart Failure NYHA Class I, Heart Failure NYHA Class II, Heart Failure NYHA Class III
Interventions
PP-MI Intervention, MI-alone Intervention
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Sep 12, 2026, 4:34 AM EDT
Completed Not applicable Interventional Results available

Developing a Positive Psychology Intervention to Promote Health Behaviors in Metabolic Syndrome: Proof-of Concept Trial

NCT03473886
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
Intervention arm: PP-MI
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 100 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 11, 2020 · Synced Sep 12, 2026, 4:34 AM EDT
Terminated Not applicable Interventional

Three Good Things (3GT) - Intervention for Transitional Care Patients

NCT04970641
View directory record Official record
Conditions
Positive Thinking, Psychology, Positive, Resilience, Psychological
Interventions
Three Good Things (3GT) Positive Psychology journaling activity
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Bloomer, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 9, 2024 · Synced Sep 12, 2026, 4:34 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Stress Management and Resiliency Training for Physicians

NCT03570853
View directory record Official record
Conditions
Burnout, Professional, Stress
Interventions
SMART-3RP
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
2
States / cities
Boston, Massachusetts • Newton, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 23, 2021 · Synced Sep 12, 2026, 4:34 AM EDT