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ClinicalTrials.gov public records Last synced Nov 14, 2026, 2:24 PM EST

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Showing 1–24 of 226 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Posterior Approach Clear all
Active, not recruiting Not applicable Interventional

Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds (PRIMARY)

NCT05051033
View directory record Official record
Conditions
Mitral Valve Regurgitation
Interventions
Mitral valve repair, Transcatheter edge-to-edge repair
Procedure · Device
Lead sponsor
Annetine Gelijns
Other
Eligibility
60 Years and older
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2034
U.S. locations
28
States / cities
Los Angeles, California • San Francisco, California • Stanford, California + 19 more
Source: ClinicalTrials.gov public record
Updated Oct 27, 2026 · Synced Nov 14, 2026, 2:24 PM EST
Completed Not applicable Interventional

Multicenter Study for Robotic Arm-assisted THA 4.0 System: Hip Spine Relationship

NCT04646096
View directory record Official record
Conditions
Osteoarthritis, Hip, Hip Disease
Interventions
MAKO THA 4.0 System
Device
Lead sponsor
American Hip Institute
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Des Plaines, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 29, 2025 · Synced Nov 14, 2026, 2:24 PM EST
Terminated Not applicable Interventional

Early Feasibility Study of the PLAR Implant and Delivery System to Treat Degenerative Mitral Regurgitation

NCT04666480
View directory record Official record
Conditions
Degenerative Mitral Valve Disease
Interventions
Transcatheter mitral valve repair
Device
Lead sponsor
Polares Medical SA
Industry
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 20, 2023 · Synced Nov 14, 2026, 2:24 PM EST
Completed Phase 3 Interventional Results available

Spinal Manipulation and Patient Self-Management for Preventing Acute to Chronic Back Pain

NCT03581123
View directory record Official record
Conditions
Acute Pain, Low Back Pain, Mechanical
Interventions
Supported-Self Management (SSM), Spinal Manipulation Therapy (SMT), SMT + SSM, Standard Medical Care (SMC)
Behavioral · Other · Combination Product + 1 more
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
3
States / cities
Minneapolis, Minnesota • Pittsburgh, Pennsylvania • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 16, 2025 · Synced Nov 14, 2026, 2:24 PM EST
Recruiting Phase 4 Interventional

Dual Mobility Acetabular Cups in Revision TJA

NCT04090359
View directory record Official record
Conditions
Dislocation, Hip
Interventions
Dual Mobility Implant, Conventional, single-bearing implant
Device
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
322 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2036
U.S. locations
2
States / cities
New York, New York • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Nov 14, 2026, 2:24 PM EST
Withdrawn Not applicable Interventional Accepts healthy volunteers

Internet-based Reiki for Tinnitus 2021

NCT04988399
View directory record Official record
Conditions
Tinnitus
Interventions
Reiki
Other
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated May 31, 2023 · Synced Nov 14, 2026, 2:24 PM EST
Completed Not applicable Interventional

A Randomized Controlled Trial of Best Approach to Care Compared to Diversified Chiropractic Adjustive Technique

NCT00163124
View directory record Official record
Conditions
Low Back Pain, Headache, Shoulder Pain
Interventions
spinal manipulation & patient education/nutrition
Procedure
Lead sponsor
Parker College of Chiropractic
Other
Eligibility
18 Years to 90 Years
Enrollment
155 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 13, 2005 · Synced Nov 14, 2026, 2:24 PM EST
Recruiting Not applicable Interventional

OCD LIFU Target Engagement

NCT07558148
View directory record Official record
Conditions
Obsessive Compulsive Disorder (OCD)
Interventions
Low Intensity Focused Ultrasound
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 60 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Nov 14, 2026, 2:24 PM EST
Completed No phase listed Observational Accepts healthy volunteers Results available

Technical Efficacy of a Direction Specific Radiofrequency Device in the Performance of Lumbar Medial Branch Neurotomies

NCT02120625
View directory record Official record
Conditions
Low Back Pain
Interventions
Lumbar MB RFN
Device
Lead sponsor
Nimbus Concepts, LLC
Industry
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Greenwood Village, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 28, 2017 · Synced Nov 14, 2026, 2:24 PM EST
Completed Phase 3 Interventional Accepts healthy volunteers Results available

PeriOcular and INTravitreal Corticosteroids for Uveitic Macular Edema Trial

NCT02374060
View directory record Official record
Conditions
Macular Edema, Uveitis
Interventions
Periocular triamcinolone 40 mg, Intravitreal triamcinolone 4 mg, Dexamethasone intravitreal implant
Drug
Lead sponsor
JHSPH Center for Clinical Trials
Other
Eligibility
18 Years and older
Enrollment
192 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
23
States / cities
Los Angeles, California • San Francisco, California • Miami, Florida + 17 more
Source: ClinicalTrials.gov public record
Updated Dec 4, 2018 · Synced Nov 14, 2026, 2:24 PM EST
Completed Not applicable Interventional Accepts healthy volunteers Results available

Detection of Clinically Significant Prostate Cancer Using Transperineal Targeted Biopsy Compared to Standard Transrectal Biopsy

NCT03044197
View directory record Official record
Conditions
Prostate Cancer, Magnetic Resonance Imaging, Target Lesion, Fusion Biopsy, Clinically Significant Prostate Cancer, Transperineal
Interventions
MRI/ultrasound transperineal prostate biopsy, transrectal ultrasound-guided prostate biopsy
Device
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 75 Years · Male only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 5, 2019 · Synced Nov 14, 2026, 2:24 PM EST
Completed Early Phase 1 Interventional Results available

A Novel Approach for Brain Stimulation in Severe Stroke

NCT03868410
View directory record Official record
Conditions
Stroke
Interventions
New Repetitive Magnetic Stimulation (rTMS) Approach, Conventional Repetitive Magnetic Stimulation (rTMS) Approach
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 90 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 5, 2025 · Synced Nov 14, 2026, 2:24 PM EST
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cluster-randomized Controlled Trial of Mindfulness-Based Cognitive Therapy Effects on Anxiety and Stress

NCT06019299
View directory record Official record
Conditions
Anxiety, Stress
Interventions
Mindfulness Practice
Behavioral
Lead sponsor
Michigan State University
Other
Eligibility
17 Years to 42 Years
Enrollment
289 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
East Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 12, 2026 · Synced Nov 14, 2026, 2:24 PM EST
Completed Not applicable Interventional

Preventing the Obturator Nerve Reflex

NCT01547637
View directory record Official record
Conditions
Bladder Injury
Interventions
Obturator nerve block
Procedure
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
35 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 31, 2018 · Synced Nov 14, 2026, 2:24 PM EST
Completed Not applicable Interventional

Anterior Orientation vs Posterior Orientation in Per Oral Endoscopic Myotomy POEM for the Treatment of Achalasia

NCT03228758
View directory record Official record
Conditions
Achalasia
Interventions
Per Oral Endoscopic Myotomy
Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Mineola, New York
Source: ClinicalTrials.gov public record
Updated May 5, 2020 · Synced Nov 14, 2026, 2:24 PM EST
Completed Not applicable Interventional

POEM Anterior Versus Posterior Approach

NCT02454335
View directory record Official record
Conditions
Achalasia
Interventions
Peroral Endoscopic Myotomy
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 2, 2018 · Synced Nov 14, 2026, 2:24 PM EST
Active, not recruiting Not applicable Interventional

SMART Stepped Care Management for Low Back Pain in the Military Health System

NCT04172038
View directory record Official record
Conditions
Low Back Pain, Chronic Pain, Military Personnel, Veterans
Interventions
Physical Therapy, Move 2 Health (M2H), MORE Mindfulness
Behavioral
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
850 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
4
States / cities
Schofield Barracks, Hawaii • San Antonio, Texas • Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Jan 14, 2025 · Synced Nov 14, 2026, 2:24 PM EST
Terminated Phase 3 Interventional Results available

DIAM™ Spinal Stabilization System vs. Decompression, Formerly vs. Posterolateral Fusion

NCT00627497
View directory record Official record
Conditions
Degenerative Lumbar Spinal Stenosis
Interventions
Single-Level Posterior Decompression, DIAM Spinal Stabilization, Fusion
Procedure · Device
Lead sponsor
Medtronic Spinal and Biologics
Industry
Eligibility
35 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
9
States / cities
Fremont, California • Jacksonville, Florida • Melbourne, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Jan 5, 2021 · Synced Nov 14, 2026, 2:24 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Agitation in People With Dementia: the Customized Activity Trial

NCT01892579
View directory record Official record
Conditions
Dementia
Interventions
Tailored Activity Program, Home Safety and Education Program
Behavioral · Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years and older
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 23, 2019 · Synced Nov 14, 2026, 2:24 PM EST
Not listed Phase 1 Interventional

Behavioral Activation and HIV Risk Reduction for Men Who Have Sex With Men With Crystal Meth Abuse

NCT01255280
View directory record Official record
Conditions
Crystal Methamphetamine Abuse, Crystal Methamphetamine Dependence
Interventions
Behavioral Activation Therapy and Risk Reduction Counseling (BAT-RR), Information, Motivation, Behavioral skills change approach to sexual risk reduction
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older · Male only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 1, 2012 · Synced Nov 14, 2026, 2:24 PM EST
Recruiting Not applicable Interventional

A Multi-Site Feasibility Trial of Embedded Emergency Department Physical Therapy

NCT07224945
View directory record Official record
Conditions
Low Back Pain
Interventions
Embedded Emergency Department Physical Therapy, Usual Care
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Chicago, Illinois • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Nov 14, 2026, 2:24 PM EST
Withdrawn Not applicable Interventional

PNS vs RFA for Facet Joint Pain

NCT05952518
View directory record Official record
Conditions
Facet Joint Pain
Interventions
Sprint PNS system, Radiofrequency Ablation
Device · Procedure
Lead sponsor
Penn State University
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 22, 2026 · Synced Nov 14, 2026, 2:24 PM EST
Completed Not applicable Interventional

Helping Individuals With Firearm Injuries

NCT02630225
View directory record Official record
Conditions
Wounds, Gunshot
Interventions
Critical Time Intervention, Treatment as Usual, Motivational Interviewing, Multi-Agency Attention
Behavioral · Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
232 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 6, 2020 · Synced Nov 14, 2026, 2:24 PM EST
Completed Not applicable Interventional Accepts healthy volunteers Results available

Acupuncture Approaches for Chronic Pain

NCT02456727
View directory record Official record
Conditions
Chronic Pain, Osteoarthritis, Neck Pain, Back Pain
Interventions
Group/Community Acupuncture, Individual Acupuncture
Procedure
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
21 Years and older
Enrollment
779 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Sep 18, 2020 · Synced Nov 14, 2026, 2:24 PM EST