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ClinicalTrials.gov public records Last synced Oct 15, 2026, 7:35 AM EDT

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Showing 649–672 of 836 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Posttraumatic Stress Disorder (PTSD) Clear all
Recruiting Not applicable Interventional

Promoting Improved Functioning Among People Experiencing Stressful Situations

NCT06482567
View directory record Official record
Conditions
Acute Stress Reaction
Interventions
iCOVER, Physical Presence with Reassurance
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 50 Years
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
5
States / cities
Belmont, Massachusetts • Worcester, Massachusetts • Detroit, Michigan + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 9, 2025 · Synced Oct 15, 2026, 7:35 AM EDT
Completed Phase 4 Interventional Results available

Combined Mirtazapine and SSRI Treatment of PTSD: A Placebo-Controlled Trial

NCT01178671
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Mirtazapine, Sertraline, Sugar pill
Drug · Other
Lead sponsor
Research Foundation for Mental Hygiene, Inc.
Other
Eligibility
18 Years to 75 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 8, 2016 · Synced Oct 15, 2026, 7:35 AM EDT
Completed Phase 2 Interventional Results available

NAC for Treating Comorbid PTSD and SUD

NCT02911285
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD), Alcohol Use Disorder (AUD), Substance Use Disorder (SUD)
Interventions
N-acetylcysteine, Placebo, Cognitive behavioral therapy
Drug · Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 75 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
2
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 19, 2021 · Synced Oct 15, 2026, 7:35 AM EDT
Not yet recruiting No phase listed Observational

Exploring Clinical Study Experiences of People With Post Traumatic Stress Disorder

NCT06146049
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Not listed
Lead sponsor
Power Life Sciences Inc.
Industry
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 24, 2023 · Synced Oct 15, 2026, 7:35 AM EDT
Completed No phase listed Observational

Predicting Treatment Response Using Psychophysiologic Reactivity Measures

NCT01571245
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Not listed
Lead sponsor
Central Arkansas Veterans Healthcare System
Federal
Eligibility
18 Years to 60 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
North Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Dec 15, 2015 · Synced Oct 15, 2026, 7:35 AM EDT
Completed Phase 2 Interventional Results available

The Safety and Tolerability of COMP360 in Participants With Post-traumatic Stress Disorder

NCT05312151
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Psilocybin
Drug
Lead sponsor
COMPASS Pathways
Industry
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
2
States / cities
Rockville, Maryland • New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 13, 2025 · Synced Oct 15, 2026, 7:35 AM EDT
Completed Not applicable Interventional Results available

Narrative Exposure Therapy (NET)

NCT03777553
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Narrative Exposure Therapy for Justice-Involved Veterans
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 19, 2024 · Synced Oct 15, 2026, 7:35 AM EDT
Not listed Not applicable Interventional

Prevention of Posttraumatic Stress Disorder (PTSD) With Early Hydrocortisone Treatment: Pilot

NCT00597857
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Hydrocortisone, placebo
Drug
Lead sponsor
Kent State University
Other
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Akron, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 28, 2009 · Synced Oct 15, 2026, 7:35 AM EDT
Completed Not applicable Interventional Results available

Image-guided, Robotically Delivered Transcranial Magnetic Stimulation Treatment for Combat-Related Post-Traumatic Stress Disorder

NCT02853032
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Active repetitive transcranial magnetic stimulation, robotic arm, Sham repetitive transcranial magnetic stimulation
Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 65 Years
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Nov 3, 2020 · Synced Oct 15, 2026, 7:35 AM EDT
Completed Phase 2 Interventional Results available

Risperidone Treatment for Military Service Related Chronic Post Traumatic Stress Disorder

NCT00099983
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Risperidone, Placebo
Drug
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
296 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
20
States / cities
Tuscaloosa, Alabama • San Diego, California • San Francisco, California + 17 more
Source: ClinicalTrials.gov public record
Updated Aug 22, 2014 · Synced Oct 15, 2026, 7:35 AM EDT
Completed Not applicable Interventional Results available

One-day Life Skills Workshop for Veterans With TBI, Pain, and Psychopathology: Evaluating Efficacy and Mechanism of Change

NCT04143243
View directory record Official record
Conditions
Traumatic Brain Injury, Chronic Pain, Post Traumatic Stress Disorder, Depression, Anxiety
Interventions
ACT on Life, Education, Resources, and Support
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 8, 2025 · Synced Oct 15, 2026, 7:35 AM EDT
Completed Phase 3 Interventional Results available

Telemental Health and Cognitive Processing Therapy for Rural Combat Veterans With Posttraumatic Stress Disorder

NCT00879255
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Cognitive Processing Therapy Group Videoteleconference, Cognitive Processing Therapy Group In-Person
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older · Male only
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated May 12, 2015 · Synced Oct 15, 2026, 7:35 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Labor Education to Reduce Postpartum Traumatic Stress

NCT06992791
View directory record Official record
Conditions
Postpartum Complication, Posttraumatic Stress Symptoms
Interventions
Prenatal Education on Childbirth
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 51 Years · Female only
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Oct 15, 2026, 7:35 AM EDT
Completed Not applicable Interventional

Mechanistic Pathways of Mindfulness Meditation in Post-traumatic Stress Disorder.

NCT00778960
View directory record Official record
Conditions
Post-Traumatic Stress Disorders
Interventions
Slow Breathing, Meditation, Meditation and slow breathing, Sitting Quietly
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
25 Years to 65 Years
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 13, 2015 · Synced Oct 15, 2026, 7:35 AM EDT
Completed Not applicable Interventional

Trauma-focused Psychodynamic Psychotherapy for LGBT Patients With Post-traumatic Stress Disorder

NCT04532996
View directory record Official record
Conditions
Complex Post-Traumatic Stress Disorder, Post-traumatic Stress Disorder
Interventions
Trauma-focused psychodynamic psychotherapy
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 7, 2021 · Synced Oct 15, 2026, 7:35 AM EDT
Recruiting Phase 1 Interventional

Group Psilocybin-Assisted Therapy for Post-Traumatic Stress Disorder

NCT07506395
View directory record Official record
Conditions
PTSD
Interventions
Psilocybin
Drug
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years to 89 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 15, 2026, 7:35 AM EDT
Completed Phase 4 Interventional Results available

Secondary Prevention With Paroxetine vs. Placebo in Subthreshold Posttraumatic Stress Disorder (PTSD)

NCT00560612
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Paroxetine, Placebo
Drug
Lead sponsor
Durham VA Medical Center
Federal
Eligibility
18 Years to 55 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 18, 2019 · Synced Oct 15, 2026, 7:35 AM EDT
Completed Not applicable Interventional Results available

DoD PTSD November 13 - Information Processing Modification in the Treatment of PTSD

NCT00604045
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Attention Bias Modification (ABM), Attention Control Condition (ACC)
Behavioral
Lead sponsor
San Diego State University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 28, 2014 · Synced Oct 15, 2026, 7:35 AM EDT
Terminated Not applicable Interventional Results available

Prazosin for Treating Noncombat Trauma Post-Traumatic Stress Disorder

NCT00183430
View directory record Official record
Conditions
Post-Traumatic Stress Disorder, Sleep Initiation and Maintenance Disorders
Interventions
Prazosin, Placebo, Psychotherapy
Drug · Behavioral
Lead sponsor
Seattle Institute for Biomedical and Clinical Research
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2010
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 14, 2018 · Synced Oct 15, 2026, 7:35 AM EDT
Completed Not applicable Interventional

Effects of Narrative Writing Duration and Post-writing Processing Instructions on PTSD

NCT01773811
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD)
Interventions
Narrative Writing: Trauma-Assigned, Narrative Writing: Trauma-Spontaneous
Behavioral
Lead sponsor
University of Mississippi, Oxford
Other
Eligibility
18 Years and older
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
University, Mississippi
Source: ClinicalTrials.gov public record
Updated May 15, 2014 · Synced Oct 15, 2026, 7:35 AM EDT
Not yet recruiting Not applicable Interventional

Preventing Perinatal Anxiety: Testing an Internet-delivered Intervention

NCT07071025
View directory record Official record
Conditions
Postpartum Disorder
Interventions
Preventing Postpartum Onset Distress (P-POD), Anxiety Education (ANX-ED)
Behavioral
Lead sponsor
West Virginia University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Jul 17, 2025 · Synced Oct 15, 2026, 7:35 AM EDT
Completed No phase listed Observational

Yoga as a Therapy for Traumatic Experiences

NCT00269490
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Yoga Nidra
Behavioral
Lead sponsor
Samueli Institute for Information Biology
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jan 28, 2008 · Synced Oct 15, 2026, 7:35 AM EDT
Completed Phase 4 Interventional Results available

An Open Label Pilot Study of Adjunctive Asenapine for the Treatment of Posttraumatic Stress Disorder

NCT01587118
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Adjunctive asenapine
Drug
Lead sponsor
Lori Davis, MD
Other
Eligibility
19 Years to 65 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Tuscaloosa, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 11, 2019 · Synced Oct 15, 2026, 7:35 AM EDT
Completed Phase 1 Interventional

Examining the Effectiveness of an Early Psychological Intervention to Prevent Post-Traumatic Stress Disorder

NCT00895518
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Prolonged Exposure (PE) Therapy
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years
Enrollment
139 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 8, 2016 · Synced Oct 15, 2026, 7:35 AM EDT