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ClinicalTrials.gov public records Last synced Oct 15, 2026, 8:15 AM EDT

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Showing 673–696 of 836 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Posttraumatic Stress Disorder (PTSD) Clear all
Completed Phase 4 Interventional Results available

Pimavanserin for Insomnia In Veterans With Posttraumatic Stress Disorder

NCT04188392
View directory record Official record
Conditions
Post-traumatic Stress Disorder, Insomnia
Interventions
Pimavanserin
Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 64 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 31, 2022 · Synced Oct 15, 2026, 8:15 AM EDT
Completed Not applicable Interventional

Cognitive Remediation in Posttraumatic Stress Disorder (PTSD)

NCT00850447
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Cognitive Remediation Therapy, Videogame
Other
Lead sponsor
Bronx VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Feb 2, 2012 · Synced Oct 15, 2026, 8:15 AM EDT
Not listed Not applicable Interventional

Deep Brain Stimulation of the Amygdala for Combat Post-Traumatic Stress Disorder

NCT02091843
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
DBS of the Basolateral Nucleus of the Amygdala, Medtronic Activa PC DBS of the Basolateral Nucleus of the Amygdala
Procedure · Device
Lead sponsor
VA Greater Los Angeles Healthcare System
Federal
Eligibility
25 Years to 70 Years · Male only
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 14, 2022 · Synced Oct 15, 2026, 8:15 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Development of Post Traumatic Stress Disorder After Natural Disaster

NCT01661452
View directory record Official record
Conditions
Development of PTSD After Natural Disaster
Interventions
Referral to counseling services if desired
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
629 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Dec 3, 2013 · Synced Oct 15, 2026, 8:15 AM EDT
Completed Not applicable Interventional Results available

Examining the Effect of Acupuncture on Sleep Difficulties Related to Post Traumatic Stress Disorder

NCT00868517
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Sleep Initiation and Maintenance Disorders
Interventions
True group auricular acupuncture, Sham group auricular acupuncture, Wait-List Control Group
Other
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Apr 28, 2015 · Synced Oct 15, 2026, 8:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cannabinoid Control of Fear Extinction Neural Circuits in Post-traumatic Stress Disorder

NCT02069366
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Dronabinol, Placebo
Drug
Lead sponsor
Wayne State University
Other
Eligibility
21 Years to 45 Years
Enrollment
86 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 2, 2025 · Synced Oct 15, 2026, 8:15 AM EDT
Active, not recruiting Not applicable Interventional

Stellate Ganglion Block for PTSD

NCT05169190
View directory record Official record
Conditions
Post-traumatic Stress Disorder
Interventions
Stellate Ganglion Block, Sham Stellate Ganglion Block
Procedure
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 80 Years
Enrollment
410 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
6
States / cities
Long Beach, California • Tampa, Florida • Minneapolis, Minnesota + 3 more
Source: ClinicalTrials.gov public record
Updated Dec 3, 2025 · Synced Oct 15, 2026, 8:15 AM EDT
Recruiting Phase 2Phase 3 Interventional

The Many Roads to Trauma Recovery: A Clinical Trial Comparing Empirically Supported Treatments for Veterans With Co-Morbid Posttraumatic Stress and Substance Use Disorder Symptoms

NCT07756723
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD), Substance Use Disorder (SUD)
Interventions
Trauma Informed Heart Rate Variability Biofeedback, Present Centered Therapy
Behavioral
Lead sponsor
Coatesville VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Coatesville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Oct 15, 2026, 8:15 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Ketamine Infusions for PTSD and Treatment-Resistant Depression

NCT02577250
View directory record Official record
Conditions
Depressive Disorder, Treatment-Resistant, Stress Disorders, Post-Traumatic
Interventions
Ketamine
Drug
Lead sponsor
Minneapolis Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated May 14, 2019 · Synced Oct 15, 2026, 8:15 AM EDT
Recruiting Not applicable Interventional

Prolonged Exposure Therapy to Treat Posttraumatic Stress Disorder in Pregnant Patients

NCT06670079
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Pregnancy
Interventions
Prolonged exposure therapy + incentives for therapy session attendance
Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Oct 15, 2026, 8:15 AM EDT
Not listed Phase 4 Interventional

Transcranial Magnetic Stimulation for Post-Traumatic Stress Disorder

NCT00134446
View directory record Official record
Conditions
Post-Traumatic Stress Disorders
Interventions
transcranial magnetic stimulation
Device
Lead sponsor
White River Junction Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2004
U.S. locations
1
States / cities
White River Junction, Vermont
Source: ClinicalTrials.gov public record
Updated Oct 31, 2005 · Synced Oct 15, 2026, 8:15 AM EDT
Terminated Not applicable Interventional

Blood Pressure, Heart Rate Variability & Sleep in Veterans With PTSD

NCT01920451
View directory record Official record
Conditions
Insomnia, Posttraumatic Stress Disorder, Hypertension, Cardiovascular Disease
Interventions
Cognitive-Behavioral Therapy for Insomnia (CBTI)
Behavioral
Lead sponsor
Durham VA Medical Center
Federal
Eligibility
21 Years to 65 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 6, 2014 · Synced Oct 15, 2026, 8:15 AM EDT
Completed Not applicable Interventional

Treating Post Traumatic Stress Disorder in Children Exposed to Domestic Violence

NCT00183326
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Anxiety, Depression
Interventions
Trauma-focused cognitive behavioral therapy (TF-CBT), Child-centered supportive therapy (CCT)
Behavioral
Lead sponsor
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Other
Eligibility
7 Years to 14 Years
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2015
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 5, 2018 · Synced Oct 15, 2026, 8:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Can Service Dogs Improve Activity and Quality of Life in Veterans With PTSD?

NCT02039843
View directory record Official record
Conditions
Post Traumatic Stress Disorders
Interventions
Emotional Support Dogs, Service Dogs
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
287 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
4
States / cities
Decatur, Georgia • Iowa City, Iowa • Portland, Oregon + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 1, 2023 · Synced Oct 15, 2026, 8:15 AM EDT
Completed Phase 2 Interventional Results available

Phase II Study of BNC210 in PTSD

NCT02933606
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
BNC210, Placebo
Drug
Lead sponsor
Bionomics Limited
Industry
Eligibility
18 Years to 70 Years
Enrollment
193 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
20
States / cities
Oceanside, California • Rancho Mirage, California • Redlands, California + 17 more
Source: ClinicalTrials.gov public record
Updated Feb 27, 2023 · Synced Oct 15, 2026, 8:15 AM EDT
Completed Not applicable Interventional

The PRISM Pilot Trial for Post-Traumatic Stress Disorder

NCT04891614
View directory record Official record
Conditions
Post-Traumatic Stress Disorder (PTSD)
Interventions
PRISM
Device
Lead sponsor
GrayMatters Health Ltd.
Industry
Eligibility
22 Years to 65 Years
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 1, 2022 · Synced Oct 15, 2026, 8:15 AM EDT
Completed Not applicable Interventional Results available

Effectiveness of Prazosin in Bulimic Patients Experiencing Nightmares Due to PTSD

NCT02382848
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Bulimia Nervosa
Interventions
Prazosin, Placebo
Drug
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 16, 2019 · Synced Oct 15, 2026, 8:15 AM EDT
Completed Not applicable Interventional Results available

Prolonged Exposure (PE) for Post Traumatic Stress Disorder (PTSD): Telemedicine Versus In Person

NCT01102764
View directory record Official record
Conditions
PTSD
Interventions
Telemedicine, In Person
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 99 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 4, 2019 · Synced Oct 15, 2026, 8:15 AM EDT
Completed Not applicable Interventional Results available

Prazosin Augmentation of Outpatient Treatment of Alcohol Use Disorders in Active Duty Soldiers With and Without PTSD

NCT02226367
View directory record Official record
Conditions
Alcohol Use Disorders, Stress Disorders, Posttraumatic, Combat Disorders
Interventions
prazosin hydrochloride, placebo
Drug
Lead sponsor
Seattle Institute for Biomedical and Clinical Research
Other
Eligibility
21 Years and older
Enrollment
158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Feb 3, 2023 · Synced Oct 15, 2026, 8:15 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Sympathetic Overactivity in Post-traumatic Stress Disorder

NCT01627301
View directory record Official record
Conditions
Post-traumatic Stress Disorder, Prehypertension
Interventions
Device-Guided Breathing (DGB), Sham DGB, Transcutaneous Vagal Nerve Stimulation (tVNS), Sham tVNS
Device
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2027
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Oct 15, 2026, 8:15 AM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Clinical Characteristics of Dementias That Occur Remotely After Traumatic Brain Injury in Retired Military Personnel

NCT01891383
View directory record Official record
Conditions
Dementia, Traumatic Brain Injury (TBI), Mild Cognitive Impairment (MCI), Chronic Traumatic Encephalopathy (CTE), Post-traumatic Stress Disorder (PTSD)
Interventions
Not listed
Lead sponsor
Uniformed Services University of the Health Sciences
Federal
Eligibility
50 Years to 95 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
2
States / cities
Yountville, California • Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jan 18, 2019 · Synced Oct 15, 2026, 8:15 AM EDT
Completed Phase 2 Interventional

Cognitive Behavioral Therapy for Post-Traumatic Stress Disorder in Individuals With Severe Mental Illness

NCT00078741
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Schizophrenia
Interventions
Cognitive Behavioral Therapy (CBT)
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
2
States / cities
Charleston, South Carolina • Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 10, 2015 · Synced Oct 15, 2026, 8:15 AM EDT
Completed Phase 3 Interventional Results available

Brexpiprazole as Combination Therapy With Sertraline in the Treatment of Adults With Post-traumatic Stress Disorder

NCT04174170
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Brexpiprazole, Sertraline, Placebo
Drug · Other
Lead sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
591 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 30, 2025 · Synced Oct 15, 2026, 8:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

fMRI Predictors of Treatment Response in Posttraumatic Stress Disorder (PTSD)

NCT01576510
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD)
Interventions
Prolonged Exposure (PE)
Behavioral
Lead sponsor
Research Foundation for Mental Hygiene, Inc.
Other
Eligibility
18 Years to 60 Years
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 24, 2014 · Synced Oct 15, 2026, 8:15 AM EDT