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ClinicalTrials.gov public records Last synced Oct 4, 2026, 3:12 AM EDT

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Showing 49–72 of 836 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Posttraumatic Stress Disorder (PTSD) Clear all
Recruiting Phase 2 Interventional

HBOT Effects on First Responders' Cognition and Well-Being

NCT07852728
View directory record Official record
Conditions
Traumatic Brain Injury, PTSD - Post Traumatic Stress Disorder, Anxiety, Depression, Post Concussion Symptoms
Interventions
Hyperbaric Oxygen Therapy (HBOT)
Drug
Lead sponsor
Summit Hyperbarics and Wellness
Other
Eligibility
18 Years to 75 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boise, Idaho
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Oct 4, 2026, 3:12 AM EDT
Active, not recruiting Phase 3 Interventional

A Pooled Analysis of Long-Term Outcomes After Inhaled Isoflurane Via the Sedaconda ACD-S Compared to Intravenous Propofol

NCT06809218
View directory record Official record
Conditions
Post-Intensive Care Syndrome, Sedation
Interventions
Inhaled isoflurane administered by Sedaconda ACD-S, Intravenous infusion of propofol
Drug
Lead sponsor
Sedana Medical
Industry
Eligibility
18 Years and older
Enrollment
312 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 5, 2025 · Synced Oct 4, 2026, 3:12 AM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers

Enhancing Exposure Therapy for Post-traumatic Stress Disorder

NCT01574118
View directory record Official record
Conditions
Chronic Posttraumatic Stress Disorder
Interventions
Revisiting the Trauma memories, Processing the trauma memories, Psychoeducation, Trauma Memory Retrieval Trial, Exposure to video clips related to the patient's trauma, Breathing retraining, Exposure Homework, Compound extinction
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 65 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2020
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Aug 29, 2022 · Synced Oct 4, 2026, 3:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cognitive Remediation for Alcohol Use Disorder and Posttraumatic Stress Disorder

NCT02929979
View directory record Official record
Conditions
Alcohol Use Disorder, PTSD, Cognitive Dysfunction
Interventions
Cognitive Training, Cognitive training placebo control
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Feb 11, 2021 · Synced Oct 4, 2026, 3:12 AM EDT
Completed Not applicable Interventional Results available

RCT of Brief CBT-I in Primary Care Veterans With Suicidal Thoughts

NCT03603717
View directory record Official record
Conditions
Insomnia, Suicidal Ideation
Interventions
Cognitive Behavioral Therapy for Insomnia, Sleep Hygiene
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
283 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
3
States / cities
Buffalo, New York • Canandaigua, New York • Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Jun 17, 2024 · Synced Oct 4, 2026, 3:12 AM EDT
Completed No phase listed Observational

Patient Participation Beliefs and Post-Traumatic Stress Disorder (PTSD)

NCT01419223
View directory record Official record
Conditions
Post-Traumatic Stress Disorder, Brain Injuries, Traumatic
Interventions
Not listed
Lead sponsor
INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Oct 29, 2013 · Synced Oct 4, 2026, 3:12 AM EDT
Completed Phase 1Phase 2 Interventional Results available

A Study to Assess the Use of Methylone in the Treatment of PTSD

NCT05741710
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Methylone, Placebo
Drug
Lead sponsor
Transcend Therapeutics
Industry
Eligibility
18 Years to 65 Years
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
8
States / cities
Denver, Colorado • Jacksonville, Florida • Maitland, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Oct 4, 2026, 3:12 AM EDT
Completed Not applicable Interventional

Treatment of Post Traumatic Stress Disorder in Patients With Other Mental Illnesses

NCT00053690
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Cognitive Behavior Treatment
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2004
U.S. locations
1
States / cities
Claremont, New Hampshire
Source: ClinicalTrials.gov public record
Updated Sep 10, 2013 · Synced Oct 4, 2026, 3:12 AM EDT
Not listed Not applicable Interventional

Trauma-Focused Cognitive Behavior Therapy for Youth: Effectiveness in a Community Setting

NCT01649141
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Trauma-Focused Cognitive Behavioral Therapy
Behavioral
Lead sponsor
Delaware Division of Prevention and Behavioral Health Services
Government
Eligibility
7 Years to 17 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
Wilmington, Delaware
Source: ClinicalTrials.gov public record
Updated Jul 25, 2012 · Synced Oct 4, 2026, 3:12 AM EDT
Completed Not applicable Interventional

Stress Reactivity in Veterans Receiving Pharmacological Treatment for PTSD and Alcohol Dependence

NCT00923923
View directory record Official record
Conditions
Post-traumatic Stress Disorder, Alcohol Dependence
Interventions
stress
Behavioral
Lead sponsor
Yale University
Other
Eligibility
21 Years to 65 Years
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 14, 2016 · Synced Oct 4, 2026, 3:12 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

A Randomized Clinical Trial of Cognitive-Behavioral Treatment for Post-Traumatic Stress Disorders in Women

NCT00032617
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Prolonged Exposure, Present Centered Therapy
Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older · Female only
Enrollment
284 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2006
U.S. locations
13
States / cities
Denver, Colorado • Bay Pines, Florida • Decatur, Georgia + 10 more
Source: ClinicalTrials.gov public record
Updated Sep 24, 2010 · Synced Oct 4, 2026, 3:12 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Neurobiological Similarities of Tinnitus and PTSD

NCT05981391
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Tinnitus
Interventions
resting-state functional MRI, Clinician Administered PTSD Scale for the DSM-5 (CAPS-5), Tympanometry, Tinnitus Assessment, Otoscopy, Pure tone air and bone-conduction, Speech testing, Loudness Discomfort, Quick Speech in Noise Test, Distortion-Product Otoacoustic Emissions (DPOAE)
Diagnostic Test
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 8, 2025 · Synced Oct 4, 2026, 3:12 AM EDT
Terminated Phase 3 Interventional Results available

Brexpiprazole as an Adjunctive Treatment to Paroxetine or Sertraline in Adult Patients Suffering From Post-traumatic Stress Disorder (PTSD)

NCT01987960
View directory record Official record
Conditions
Post-traumatic Stress Disorder, PTSD
Interventions
Placebo, Brexpiprazole
Drug
Lead sponsor
H. Lundbeck A/S
Industry
Eligibility
18 Years to 65 Years
Enrollment
417 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
22
States / cities
Los Angeles, California • Riverside, California • San Diego, California + 17 more
Source: ClinicalTrials.gov public record
Updated Mar 13, 2017 · Synced Oct 4, 2026, 3:12 AM EDT
Recruiting Not applicable Interventional

Cognitive Processing Therapy (CPT) for Perinatal Posttraumatic Stress Disorder (PTSD)

NCT07060144
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD), Pregnancy
Interventions
Regular CPT, Massed CPT
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 46 Years · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Oct 4, 2026, 3:12 AM EDT
Withdrawn Phase 2 Interventional Accepts healthy volunteers

Adjunctive Pregnenolone in Post-Traumatic Stress Disorder (PTSD) and Depression in Operations Enduring Freedom and Iraqi Freedom (OEF/OIF) Veterans

NCT00993629
View directory record Official record
Conditions
Post-traumatic Stress Disorder, Major Depressive Disorder
Interventions
pregnenolone, placebo
Drug
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 55 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 27, 2014 · Synced Oct 4, 2026, 3:12 AM EDT
Completed Not applicable Interventional Results available

Efficacy of a Brief Nightmare Treatment for Veterans

NCT01220401
View directory record Official record
Conditions
Sleep Disorders, PTSD, Suicide
Interventions
exposure, relaxation, and rescription therapy
Behavioral
Lead sponsor
University of Tulsa
Other
Eligibility
18 Years to 99 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 30, 2019 · Synced Oct 4, 2026, 3:12 AM EDT
Recruiting Phase 2 Interventional

Induction of Dreaming With EEG and Anesthesia for Post-traumatic Stress Disorder

NCT06577636
View directory record Official record
Conditions
PTSD, Post-traumatic Stress Disorder
Interventions
Propofol
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 70 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 4, 2026, 3:12 AM EDT
Completed Not applicable Interventional

Cognitive Behavioral Treatment of Posttraumatic Stress Disorder Enhanced by Virtual Reality for Individuals With PTSD and Substance Abuse

NCT00656344
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Substance Abuse
Interventions
Cognitive behavioral treatment enhanced by virtual reality
Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 70 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 10, 2013 · Synced Oct 4, 2026, 3:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Attention Bias Modification Treatment for Warzone-Related Posttraumatic Stress Disorder (PTSD)

NCT01564667
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Attention Bias Modification Training Protocol
Behavioral
Lead sponsor
Creighton University
Other
Eligibility
19 Years to 65 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Jan 14, 2016 · Synced Oct 4, 2026, 3:12 AM EDT
Completed Not applicable Interventional Results available

Trauma-informed Collaborative Care for Low-income African Americans With PTSD

NCT03591107
View directory record Official record
Conditions
PTSD
Interventions
PTSD Care Management (PCM), Minimally Enhanced Usual Care (MEU)
Other
Lead sponsor
RAND
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Dec 2, 2022 · Synced Oct 4, 2026, 3:12 AM EDT
Recruiting Not applicable Interventional

Treatments for Insomnia in Veterans With PTSD

NCT05194930
View directory record Official record
Conditions
Insomnia, PTSD
Interventions
The ABC of Insomnia (Acceptance and the Behavioral Changes to treat Insomnia), Cognitive-Behavioral Therapy for Insomnia
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
2
States / cities
Sepulveda, California • Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Oct 4, 2026, 3:12 AM EDT
Completed No phase listed Observational

Brain Indices of Risk for Posttraumatic Stress Disorder (PTSD) After Mild Traumatic Brain Injury (mTBI)

NCT01625962
View directory record Official record
Conditions
PTSD
Interventions
Not listed
Lead sponsor
INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium
Other
Eligibility
18 Years to 50 Years
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
2
States / cities
Bethesda, Maryland • Fort Belvoir, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 1, 2018 · Synced Oct 4, 2026, 3:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

fMRI Predictors of Treatment Response in Posttraumatic Stress Disorder (PTSD)

NCT01576510
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD)
Interventions
Prolonged Exposure (PE)
Behavioral
Lead sponsor
Research Foundation for Mental Hygiene, Inc.
Other
Eligibility
18 Years to 60 Years
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 24, 2014 · Synced Oct 4, 2026, 3:12 AM EDT
Completed Phase 2 Interventional

Cognitive Behavioral Therapy for Post Traumatic Stress Disorder in Addiction Treatment

NCT01456338
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Substance-Related Disorders
Interventions
Cognitive Behavioral Therapy for PTSD, Individual Addiction Counseling
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
6
States / cities
Hartford, Connecticut • Lebanon, New Hampshire • Manchester, New Hampshire + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 20, 2011 · Synced Oct 4, 2026, 3:12 AM EDT