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ClinicalTrials.gov public records Last synced Oct 16, 2026, 10:39 AM EDT

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Showing 793–816 of 836 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Posttraumatic Stress Disorder (PTSD) Clear all
Completed Phase 2 Interventional Results available

Open Label Multi-Site Study of Safety and Effects of MDMA-assisted Therapy for Treatment of PTSD

NCT03282123
View directory record Official record
Conditions
PTSD
Interventions
Midomafetamine, Manualized therapy
Drug · Behavioral
Lead sponsor
Resilient Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
12
States / cities
North Hollywood, California • San Francisco, California • Boulder, Colorado + 7 more
Source: ClinicalTrials.gov public record
Updated Jun 5, 2025 · Synced Oct 16, 2026, 10:39 AM EDT
Completed Phase 2Phase 3 Interventional

Levetiracetam in Post-Traumatic Stress Disorder

NCT00413296
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
levetiracetam, Placebo, Levetriracetam
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 21, 2014 · Synced Oct 16, 2026, 10:39 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Complementary and Alternative Interventions for Veterans With Posttraumatic Stress Disorder

NCT01512303
View directory record Official record
Conditions
PTSD
Interventions
Sudarshan Kriya Yoga, Mindfulness-Based Stress Reduction
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 50 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 7, 2018 · Synced Oct 16, 2026, 10:39 AM EDT
Completed Not applicable Interventional

Occupational Therapy Driving Intervention for Returning Combat Veterans.

NCT02764983
View directory record Official record
Conditions
Traumatic Brain Injury (TBI), Post Traumatic Stress Disorder (PTSD)
Interventions
Driving Behavior Interview, Fitness-to-Drive Screening Measure, Clinical Driving Assessment, Propensity for Angry Driving Scale, Community Integration Questionnaire, Satisfaction with Life Questionnaire, Driving simulator evaluation, Focus Group Discussion Interview Guide
Behavioral · Other · Procedure
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 85 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
2
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Dec 17, 2018 · Synced Oct 16, 2026, 10:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Psychophysiologic Predictors of Post-deployment Mental Health Outcomes

NCT00838006
View directory record Official record
Conditions
Post-traumatic Stress Disorder
Interventions
heart rate variability biofeedback, Cognitive bias modification training, Sham Comparator
Device
Lead sponsor
Biomedical Research Foundation
Other
Eligibility
18 Years to 60 Years
Enrollment
426 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2013
U.S. locations
1
States / cities
Blackstone, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 2, 2020 · Synced Oct 16, 2026, 10:39 AM EDT
Completed Not applicable Interventional

Healing Touch & Guided Imagery for Posttraumatic Stress Disorder Symptoms

NCT01348750
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Healing Touch & Guided Imagery
Other
Lead sponsor
Scripps Center for Integrative Medicine
Other
Eligibility
18 Years and older
Enrollment
123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated May 5, 2011 · Synced Oct 16, 2026, 10:39 AM EDT
Completed Not applicable Interventional

Structured Treatment of Pain (STOP) Study

NCT01768650
View directory record Official record
Conditions
Traumatic Brain Injury, Chronic Pain
Interventions
Self-Management #1, Self-Management #2
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
231 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
4
States / cities
Seattle, Washington • Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Sep 9, 2019 · Synced Oct 16, 2026, 10:39 AM EDT
Completed Phase 3 Interventional

Cognitive Behavioral Therapy (CBT) for Posttraumatic Stress Disorder (PTSD) in Community Addiction Treatment

NCT01457391
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Substance-Related Disorders
Interventions
Cognitive Behavioral Therapy, Individual Addiction Counseling, Treatment-as-usual
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
443 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
4
States / cities
Berlin Corners, Vermont • Brattleboro, Vermont • Burlington, Vermont + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 16, 2015 · Synced Oct 16, 2026, 10:39 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Project SERVE: Post Deployment Functioning

NCT01123642
View directory record Official record
Conditions
Post-traumatic Stress Disorder, Depressive Disorder, Alcoholism
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
345 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Waco, Texas
Source: ClinicalTrials.gov public record
Updated Aug 20, 2018 · Synced Oct 16, 2026, 10:39 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Imaging SV2A in Mood Disorders

NCT02734602
View directory record Official record
Conditions
Major Depressive Disorder, Post-Traumatic Stress Disorder
Interventions
Ketamine
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 70 Years
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2027
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Oct 16, 2026, 10:39 AM EDT
Completed Not applicable Interventional Results available

Adapting and Piloting Behavioral Activation for Veterans With Alcohol Use Disorder and Posttraumatic Stress Disorder

NCT06249386
View directory record Official record
Conditions
Alcohol Use Disorder, Posttraumatic Stress Disorder
Interventions
Behavioral Activation (BA), Relapse Prevention (RP)
Behavioral
Lead sponsor
RTI International
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 16, 2026, 10:39 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Role of Substance P in Post-Traumatic Stress Disorder

NCT00102102
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
[18F]SPA-RQ
Drug
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
Not listed
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2006
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 16, 2026, 10:39 AM EDT
Completed Not applicable Interventional Results available

Psychosocial Rehabilitation After Moral Injury and Loss With Adaptive Disclosure

NCT03056157
View directory record Official record
Conditions
Post-traumatic Stress Disorder, Moral Injury, Traumatic Loss
Interventions
Adaptive Disclosure for Moral Injury and Loss, Present Centered Therapy
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
174 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
5
States / cities
San Diego, California • San Francisco, California • Boston, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 3, 2024 · Synced Oct 16, 2026, 10:39 AM EDT
Completed Phase 2 Interventional Results available

D-cycloserine Adjunctive Treatment for Posttraumatic Stress Disorder (PTSD) in Adolescents

NCT01157429
View directory record Official record
Conditions
Posttraumatic Stress Disorder, PTSD
Interventions
D-cycloserine, Placebo pill, CBT
Drug · Behavioral
Lead sponsor
Tulane University School of Medicine
Other
Eligibility
13 Years to 18 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Jun 6, 2017 · Synced Oct 16, 2026, 10:39 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

High-Frequency Repetitive Transcranial Magnetic Stimulation of the Right Dorsolateral Prefrontal Cortex in PTSD

NCT02873299
View directory record Official record
Conditions
PTSD, Post Traumatic Stress Disorder
Interventions
10 Hz rTMS of the right dorsolateral prefrontal cortex, 20 Hz rTMS of the right dorsolateral prefrontal cortex
Other
Lead sponsor
United States Naval Medical Center, San Diego
Federal
Eligibility
18 Years to 65 Years
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 22, 2016 · Synced Oct 16, 2026, 10:39 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

PPG Project 3 - PET/MRI of the Brain-hematopoiesis-atherosclerosis Axis in PTSD Patients

NCT03279393
View directory record Official record
Conditions
PTSD, Trauma, Healthy
Interventions
fluorodeoxyglucose (FDG)-PET/MRI
Drug
Lead sponsor
Zahi Fayad
Other
Eligibility
30 Years to 65 Years
Enrollment
190 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
2
States / cities
Boston, Massachusetts • New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 14, 2023 · Synced Oct 16, 2026, 10:39 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Cognitive Training for Post Traumatic Stress Disorder: Effects on Cognitive, Emotional, and Brain Function

NCT01644851
View directory record Official record
Conditions
Posttraumatic Stress Disorders
Interventions
Executive function training
Behavioral
Lead sponsor
University of Missouri, Kansas City
Other
Eligibility
18 Years to 45 Years · Male only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 8, 2014 · Synced Oct 16, 2026, 10:39 AM EDT
Terminated Not applicable Interventional

To Evaluate the Efficacy of EEG-guided Magnetic Resonant Therapy in War Veterans With Posttraumatic Stress Disorder

NCT02824445
View directory record Official record
Conditions
Post-Traumatic Stress Disorders
Interventions
individualized Transcranial Magnetic Stimulation
Device
Lead sponsor
72nd Medical Group, Tinker Air Force Base
Federal
Eligibility
18 Years to 55 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jan 2, 2020 · Synced Oct 16, 2026, 10:39 AM EDT
Withdrawn Phase 4 Interventional

Pimavanserin for Insomnia in Veterans With Posttraumatic Stress Disorder: Proof of Concept

NCT04809116
View directory record Official record
Conditions
Insomnia Chronic, Posttraumatic Stress Disorder
Interventions
Pimavanserin
Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 64 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 24, 2023 · Synced Oct 16, 2026, 10:39 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Executive Dysfunction and Self-Harm Behavior: An Examination of Veterans With TBI, PTSD, or Both

NCT01334463
View directory record Official record
Conditions
Traumatic Brain Injury, Post Traumatic Stress Disorder, Suicide, Self-Injurious Behavior
Interventions
Not listed
Lead sponsor
VA Eastern Colorado Health Care System
Federal
Eligibility
18 Years to 45 Years
Enrollment
186 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2016
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 25, 2016 · Synced Oct 16, 2026, 10:39 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Feasibility and ML Training Investigation of the Senseye DT for Diagnosis of Adults with PTSD

NCT05717439
View directory record Official record
Conditions
PTSD, Generalized Anxiety Disorder, Major Depressive Disorder
Interventions
CAPS-5-R, Senseye DT
Diagnostic Test
Lead sponsor
Senseye, Inc.
Industry
Eligibility
18 Years and older
Enrollment
338 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
5
States / cities
Aurora, Colorado • Meridian, Idaho • Charleston, South Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 11, 2024 · Synced Oct 16, 2026, 10:39 AM EDT
Terminated No phase listed Observational

Study of Quality of Life in Freeman-Sheldon Syndrome and Related Conditions

NCT01307475
View directory record Official record
Conditions
Arthrogryposis, Craniofacial Abnormalities, Posttraumatic Stress Disorder, Depressive Disorder
Interventions
PTSD Checklist-Specific, Modified Flanagan Quality of Life Scale, Center for Epidemiologic Studies Depression Scale, Functional Enquiry Form, Strength, Joint ROM, Girth and Length Measurements, Study Physical Examination, PTSD, Depression, and FSS-Focused Examination, Freeman-Sheldon Specific Quality of Life Survey, Lactate, Glucose, and Adenosine Triphosphate Blood Levels
Other
Lead sponsor
Freeman-Sheldon Research Group, Inc.
Other
Eligibility
Not listed
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Buckhannon, West Virginia
Source: ClinicalTrials.gov public record
Updated Apr 4, 2017 · Synced Oct 16, 2026, 10:39 AM EDT
Recruiting Not applicable Interventional

Evaluation of the PE Coach Mobile Application Among Veterans With PTSD

NCT04959695
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
PE Coach, Prolonged exposure without PE Coach
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Oct 16, 2026, 10:39 AM EDT
Completed Phase 4 Interventional

Vilazodone for the Treatment of Posttraumatic Stress Disorder

NCT01715519
View directory record Official record
Conditions
PTSD, Depression
Interventions
Treatment (Viibryd)
Drug
Lead sponsor
Southern California Institute for Research and Education
Other
Eligibility
18 Years to 55 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
2
States / cities
Long Beach, California • Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Apr 25, 2017 · Synced Oct 16, 2026, 10:39 AM EDT