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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Pragmatic Clear all
Completed Phase 2 Interventional Results available

Modafinil Versus Amphetamines for the Treatment of Narcolepsy Type 2 and Idiopathic Hypersomnia

NCT03772314
View directory record Official record
Conditions
Idiopathic Hypersomnia, Narcolepsy Without Cataplexy
Interventions
Modafinil, Amphetamine-Dextroamphetamine
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated May 22, 2024 · Synced Sep 23, 2026, 8:55 PM EDT
Completed Not applicable Interventional Results available

Health Effects of oraL Protein Supplements in HD (The HELPS-HD Trial)

NCT02933151
View directory record Official record
Conditions
End Stage Renal Disease
Interventions
Nutritional Supplement
Dietary Supplement
Lead sponsor
Dialysis Clinic, Inc.
Industry
Eligibility
18 Years and older
Enrollment
10,457 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
2
States / cities
Jacksonville, Florida • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 4, 2024 · Synced Sep 23, 2026, 8:55 PM EDT
Completed Not applicable Interventional

Feasibility, Acceptability and Fidelity of Integrating a Navigation Intervention Into Tobacco Treatment Program

NCT07072312
View directory record Official record
Conditions
Cancer
Interventions
Adjuvant Patient Navigation for Tobacco Treatment
Behavioral
Lead sponsor
Fox Chase Cancer Center
Other
Eligibility
18 Years and older
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 17, 2025 · Synced Sep 23, 2026, 8:55 PM EDT
Completed Not applicable Interventional Results available

Pragmatic Randomized Clinical Trial to Limit Weight Gain in Pregnancy and Prevent Obesity

NCT04724330
View directory record Official record
Conditions
Pregnancy Weight Gain, Postpartum Weight Retention, Childhood Obesity, Gestational Diabetes, Overweight and Obesity
Interventions
Healthy for Two/Healthy for You
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older · Female only
Enrollment
534 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Sep 23, 2026, 8:55 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Does Batten Grafting Improve Nasal Outcomes in Septoplasty and Turbinate Reduction?

NCT05287841
View directory record Official record
Conditions
Nasal Obstruction, Septal Defect, Allergic Rhinitis, Nasal Polyps, Nasal Valve Collapse
Interventions
Batten batten graft, Septoplasty, Inferior Turbinate Reduction
Procedure
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
3
States / cities
Poplar Bluff, Missouri • New York, New York • Staten Island, New York
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Sep 23, 2026, 8:55 PM EDT
Not listed No phase listed Observational

Pectus ESC Outcomes and Comparative Effectiveness Study

NCT05063695
View directory record Official record
Conditions
Pectus Excavatum, Pain, Postoperative
Interventions
Multimodal Erector spinae catheter protocol
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
8 Years and older
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 12, 2024 · Synced Sep 23, 2026, 8:55 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Motivational Wellness Coaching to Reduce Childhood Obesity in Families and Kids

NCT05143697
View directory record Official record
Conditions
Obesity
Interventions
Wellness Coaching for Families and Kids
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
2 Years to 8 Years
Enrollment
6,600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Pasadena, California
Source: ClinicalTrials.gov public record
Updated Sep 3, 2025 · Synced Sep 23, 2026, 8:55 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Stopping Cavities Study: Diammine Silver Fluoride

NCT02536040
View directory record Official record
Conditions
Dental Caries
Interventions
38% diammine silver fluoride, Water
Drug · Other
Lead sponsor
Advantage Dental Services, LLC
Industry
Eligibility
24 Months to 60 Months
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Redmond, Oregon
Source: ClinicalTrials.gov public record
Updated Jan 22, 2020 · Synced Sep 23, 2026, 8:55 PM EDT
Enrolling by invitation Not applicable Interventional

Lumbar Extension Strengthening in Addition to Manual Therapy and Exercise for Chronic Low Back Pain

NCT07719452
View directory record Official record
Conditions
Chronic Low Back Pain (CLBP)
Interventions
Standard Physical Therapy, Lumbar Extensor Strengthening plus Standard Physical Therapy
Other
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Sep 23, 2026, 8:55 PM EDT
Not yet recruiting Not applicable Interventional

Clinician Notification to Increase Aspirin Prophylaxis for Preeclampsia Prevention

NCT07614893
View directory record Official record
Conditions
Preeclampsia, Hypertensive Disorders of Pregnancy (HDP), Pregnancy Complications, Aspirin Prophylaxis
Interventions
Clinician notification of elevated preeclampsia risk
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2030
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Sep 23, 2026, 8:55 PM EDT
Completed Not applicable Interventional Results available

COVID-19 Vaccine Text Outreach

NCT04834726
View directory record Official record
Conditions
Covid19
Interventions
Opt-In (Call-Back), Opt-in (In-Bound), Standard Message, Clinician Endorsement, Scarcity, Opt-Out Framing, Phone Call
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
16 Years and older
Enrollment
19,554 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 26, 2023 · Synced Sep 23, 2026, 8:55 PM EDT
Recruiting Phase 4 Interventional

Stanford Pragmatic Effectiveness Comparison

NCT04441034
View directory record Official record
Conditions
Chronic Pain
Interventions
Anti-convulsant medications, Anti-depressant medications
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 23, 2026, 8:55 PM EDT
Completed No phase listed Observational

Pragmatic Implementation of Mindful Awareness in Body Oriented Therapy

NCT05289024
View directory record Official record
Conditions
Non-pharmacologic Management of Chronic Pain
Interventions
Mindful Awareness in Body-Oriented Therapy
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 5, 2024 · Synced Sep 23, 2026, 8:55 PM EDT
Recruiting Not applicable Interventional

Delay AvoIding Primary Evaluation for ThRombectomy of Acute StrokE Patients With Large Vessel OCclusion in the Angiography SuiTe

NCT06825897
View directory record Official record
Conditions
Stroke, Acute
Interventions
Conventional Triage for Mechanical Thrombectomy, Direct Transfer to Angiography Suite (DTAS
Other
Lead sponsor
Santiago Ortega Gutierrez
Other
Eligibility
18 Years and older
Enrollment
2,039 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
6
States / cities
Iowa City, Iowa • Detroit, Michigan • Wyoming, Michigan + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Sep 23, 2026, 8:55 PM EDT
Completed Not applicable Interventional

Baby2Home (B2H) Mobile Health Application

NCT05595486
View directory record Official record
Conditions
COVID-19 Pandemic, Health Knowledge, Attitudes, Practice, Perinatal Depression, Mental Health Wellness, Post Partum Depression
Interventions
Baby2Home Mobile Application
Other
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
18 Years and older
Enrollment
642 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
Chicago, Illinois • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 5, 2026 · Synced Sep 23, 2026, 8:55 PM EDT
Recruiting Not applicable Interventional

Promoting Asthma Management Guidelines With Technology-Based Intervention and Care Coordination in Clinics and Schools

NCT07224061
View directory record Official record
Conditions
Asthma in Children
Interventions
PRAGMATIC-S
Behavioral
Lead sponsor
Montefiore Medical Center
Other
Eligibility
4 Years to 12 Years
Enrollment
420 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2033
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Sep 23, 2026, 8:55 PM EDT
Recruiting Phase 3 Interventional Accepts healthy volunteers

Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors

NCT07018869
View directory record Official record
Conditions
Colorectal Cancer Stage II, Colorectal Cancer Stage III
Interventions
Intervention website access, Control website access, Interview, Questionnaire Administration
Other
Lead sponsor
SWOG Cancer Research Network
Network
Eligibility
18 Years and older
Enrollment
1,057 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
376
States / cities
Anchorage, Alaska • Phoenix, Arizona • Fort Smith, Arkansas + 268 more
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Sep 23, 2026, 8:55 PM EDT
Completed Not applicable Interventional

Addressing Disability Effectively With Psychosocial Telemedicine

NCT05635292
View directory record Official record
Conditions
Crohn Disease
Interventions
Tele-CBT
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
715 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 1, 2024 · Synced Sep 23, 2026, 8:55 PM EDT
Completed Phase 2 Interventional

High-intensity Exercise and Fall Prevention Boot Camp for Parkinson's Disease

NCT02230267
View directory record Official record
Conditions
Parkinson's Disease
Interventions
High intensity exercise and balance training, Usual care arm exercise
Other
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
45 Years to 85 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated May 11, 2016 · Synced Sep 23, 2026, 8:55 PM EDT
Completed Not applicable Interventional

Pragmatic Research in Healthcare Settings to Improve Diabetes and Obesity Prevention and Care for Our Program

NCT04420936
View directory record Official record
Conditions
Diabetes, Weight Loss, Diet Habit
Interventions
MAINTAIN PRIME Lifestyle Coaching, Control tracking
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 75 Years
Enrollment
269 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Oct 28, 2025 · Synced Sep 23, 2026, 8:55 PM EDT
Completed Not applicable Interventional Results available

The MyLungHealth Study Protocol: Engaging Patients to Enable Interoperable Lung Cancer Decision Support at Scale

NCT06338592
View directory record Official record
Conditions
Lung Cancer, Lung Neoplasms/Diagnosis
Interventions
MyLungHealth, DecisionPrecision+
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
50 Years to 79 Years
Enrollment
31,303 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
New York, New York • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Mar 26, 2026 · Synced Sep 23, 2026, 8:55 PM EDT
Completed Phase 2Phase 3 Interventional

Does Prescriptive Treatment of the Hips Improve Outcomes in Patients With Low Back Pain? A Randomized Controlled Trial

NCT01900925
View directory record Official record
Conditions
Low Back Pain
Interventions
Prescriptive Hip Exercises and Manual Therapy techniques, Pragmatic low back pain treatment
Procedure
Lead sponsor
Regis University
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated May 1, 2016 · Synced Sep 23, 2026, 8:55 PM EDT
Recruiting Phase 3 Interventional

AntiThrombotic Therapy to Ameliorate Clinical Complications in Community Acquired Pneumonia

NCT05848713
View directory record Official record
Conditions
Community-acquired Pneumonia
Interventions
Heparin
Drug
Lead sponsor
University of Manitoba
Other
Eligibility
18 Years and older
Enrollment
4,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
6
States / cities
Chicago, Illinois • Jefferson, Louisiana • Portland, Maine + 3 more
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Sep 23, 2026, 8:55 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Implementation Facilitation of Exercise is Medicine Greenville

NCT07340580
View directory record Official record
Conditions
Physical Inactivity, Dyslipidemia, Obesity and Overweight, Hypertension, Diabetes, Health Care Delivery, Patients, Chronic Disease, Exercise, Physical Activity, Implementation Science
Interventions
Clinic Implementation Facilitation
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
Not listed
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Sep 23, 2026, 8:55 PM EDT