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ClinicalTrials.gov public records Last synced Oct 5, 2026, 7:50 PM EDT

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Showing 25–48 of 110 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Prefrontal transcranial magnetic brain stimulation Clear all
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Transcranial Magnetic Stimulation Treatment for Alzheimer's Disease

NCT06538311
View directory record Official record
Conditions
Alzheimer Disease, Mild Cognitive Impairment, Logopenic Progressive Aphasia, Amnestic Symptoms
Interventions
Active rTMS, Sham rTMS
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
40 Years to 99 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 5, 2026, 7:50 PM EDT
Completed Not applicable Interventional

Theta Burst Stimulation as a Tool to Decrease Drinking in Treatment-seeking Alcohol Users

NCT04154111
View directory record Official record
Conditions
Alcohol Use Disorder, Alcohol Abuse, Alcohol Dependence, Craving
Interventions
Real TBS to the vmPFC, Sham TBS to the vmPFC, Real TBS to the dlPFC, Sham TBS to the dlPFC
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
21 Years to 75 Years
Enrollment
147 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Oct 5, 2026, 7:50 PM EDT
Recruiting Not applicable Interventional

Personalized Brain Stimulation to Help Veterans Quit Smoking

NCT07050862
View directory record Official record
Conditions
Tabacco Use Disorder, rTMS
Interventions
Transcranial Magnetic Stimulation, Personalized-image-guided and E-field-modeling dose rTMS (precision TMS)
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Oct 5, 2026, 7:50 PM EDT
Completed Not applicable Interventional Results available

Brain Stimulation For Cancer Smokers

NCT03419741
View directory record Official record
Conditions
Cancer of Head and Neck, Breast Cancer, Prostate Cancer, Nicotine Dependence
Interventions
Transcranial Magnetic Stimulation Clinical Research System
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 13, 2022 · Synced Oct 5, 2026, 7:50 PM EDT
Completed Phase 2 Interventional

Study of Repetitive Transcranial Magnetic Stimulation in Parkinson's Disease

NCT00029666
View directory record Official record
Conditions
Parkinson Disease
Interventions
Neopulse Magnetic Stimulator
Device
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 5, 2026, 7:50 PM EDT
Terminated Phase 2 Interventional

fMRI-neuronavigated rTMS for the Treatment of Major Depression Associated With TBI

NCT02980484
View directory record Official record
Conditions
Major Depressive Disorder, Traumatic Brain Injury
Interventions
Active, Sham
Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 29, 2018 · Synced Oct 5, 2026, 7:50 PM EDT
Recruiting Not applicable Interventional

Home-Based Brain Stimulation for Motoric Cognitive Risk Syndrome

NCT06821568
View directory record Official record
Conditions
Alzheimer Disease and Related Dementias, Cognition, Mobility Disability
Interventions
Personalized Transcranial Direct Current Stimulation (tDCS), Active-Sham
Other
Lead sponsor
Hebrew SeniorLife
Other
Eligibility
65 Years to 90 Years
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Roslindale, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Oct 5, 2026, 7:50 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Transcranial Magnetic Brain Stimulation to Reduce Cannabis Use in Heavy Cannabis Users

NCT05401929
View directory record Official record
Conditions
Cannabis
Interventions
iTBS
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2029
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 5, 2026, 7:50 PM EDT
Active, not recruiting Not applicable Interventional

PILOT Phase: BPD Study

NCT07223619
View directory record Official record
Conditions
Borderline Personality Disorder
Interventions
Transcranial Magnetic Stimulation (TMS)
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Oct 5, 2026, 7:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Investigation of Brain Network Dynamics in Depression

NCT01931995
View directory record Official record
Conditions
Major Depressive Disorder, Recurrent
Interventions
TMS positively correlated DLPFC, TMS to negatively correlated DLPFC
Device · Procedure
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 50 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 7, 2021 · Synced Oct 5, 2026, 7:50 PM EDT
Completed Not applicable Interventional Results available

rTMS for Stimulant Use Disorders

NCT04907357
View directory record Official record
Conditions
Cocaine Use Disorder, Methamphetamine Abuse, Cocaine Dependence, Methamphetamine Dependence, Stimulant Use, Stimulant Abuse, Methamphetamine Use Disorder, Cocaine Abuse, Stimulant Use Disorder
Interventions
rTMS, Sham (Placebo)
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
129 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
4
States / cities
Winston-Salem, North Carolina • Charleston, South Carolina • Dallas, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 3, 2025 · Synced Oct 5, 2026, 7:50 PM EDT
Enrolling by invitation Not applicable Interventional

Effects of Accelerated rTMS on Sleep Architecture in Chronic Insomnia Disorder

NCT07595185
View directory record Official record
Conditions
Insomnia, Chronic Insomnia, Chronic Insomnia Disorder, Sleep Disturbance
Interventions
TMS
Device
Lead sponsor
San Francisco Neurology and Sleep Center
Other
Eligibility
18 Years to 85 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Oct 5, 2026, 7:50 PM EDT
Recruiting Not applicable Interventional

SAINT in Postpartum Depression (PPD)

NCT07210255
View directory record Official record
Conditions
Postpartum Depression (PPD)
Interventions
SAINT Neuromodulation System, Sham SAINT Stimulation
Device
Lead sponsor
Magnus Medical
Industry
Eligibility
18 Years to 45 Years · Female only
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
4
States / cities
Worcester, Massachusetts • New York, New York • Charleston, South Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 5, 2026, 7:50 PM EDT
Completed Phase 1 Interventional

Magnetic Stimulation for Parkinson Disease

NCT00029276
View directory record Official record
Conditions
Parkinson's Disease, Depression
Interventions
Prefrontal transcranial magnetic brain stimulation
Procedure
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
40 Years to 75 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2005
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 18, 2006 · Synced Oct 5, 2026, 7:50 PM EDT
Completed Phase 2Phase 3 Interventional Results available

EEG Synchronized TMS Trial for Depression

NCT03421808
View directory record Official record
Conditions
Depression
Interventions
Transcranial Magnetic Stimulation (TMS)
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years to 70 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 4, 2025 · Synced Oct 5, 2026, 7:50 PM EDT
Recruiting Not applicable Interventional

Neuromodulation and Neurorehabilitation for mTBI

NCT03819608
View directory record Official record
Conditions
Mild Traumatic Brain Injury, Post Traumatic Stress Disorder
Interventions
real iTBS, real APT, placebo APT, placebo iTBS
Device · Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 80 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
2
States / cities
Chicago, Illinois • Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 8, 2026 · Synced Oct 5, 2026, 7:50 PM EDT
Recruiting Phase 2 Interventional

Personalized Brain Stimulation to Treat Chronic Concussive Symptoms

NCT06073886
View directory record Official record
Conditions
Post-Concussion Syndrome, Concussion, Brain, Mild Traumatic Brain Injury, Head Injury, Headache, Dizziness, Cognitive Symptom, Dysautonomia, Anxiety, Irritability; Syndrome, Depression, Post-traumatic Stress Disorder
Interventions
Active cTBS, Inactive/Sham cTBS, Imaginal exposure
Device · Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 65 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Westwood, Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Oct 5, 2026, 7:50 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Magnetic Brain Stimulation for the Treatment of Adult Depression

NCT00149838
View directory record Official record
Conditions
Depression
Interventions
Prefrontal rTMS, Antidepressant Regimen, Sham Stimulation
Procedure · Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years to 70 Years
Enrollment
190 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
4
States / cities
Atlanta, Georgia • New York, New York • Charleston, South Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 28, 2018 · Synced Oct 5, 2026, 7:50 PM EDT
Recruiting Phase 2 Interventional

Psilocybin rTMS for Treatment Resistant Depression

NCT06132178
View directory record Official record
Conditions
Treatment Resistant Depression, MDD, Major Depressive Disorder, Recurrent Depression, Depression
Interventions
Psilocybin, Accelerated intermittent theta burst (aiTBS) rTMS treatment, Low-dose psilocybin, Sham Accelerated intermittent theta burst (aiTBS) rTMS treatment
Drug · Device
Lead sponsor
University of Texas at Austin
Other
Eligibility
22 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Nov 26, 2025 · Synced Oct 5, 2026, 7:50 PM EDT
Terminated Not applicable Interventional Results available

QuitFast: Evaluating Transcranial Magnetic Stimulation as a Tool to Reduce Smoking Directly Following a Quit Attempt

NCT03576768
View directory record Official record
Conditions
Smoking, Cigarette, Craving, Addiction, Nicotine
Interventions
Real cTBS, Sham cTBS, Real iTBS, Sham iTBS
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 70 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 24, 2021 · Synced Oct 5, 2026, 7:50 PM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Assessment of Traumatic Brain Injury Using Transcranial Magnetic Stimulated Evoked Potentials

NCT06963775
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Delphi-MD device (QuantalX Neuroscience Ltd., Saba Israel)
Device
Lead sponsor
Ramon Diaz-Arrastia
Other
Eligibility
18 Years and older
Enrollment
215 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 21, 2026 · Synced Oct 5, 2026, 7:50 PM EDT
Active, not recruiting Phase 2 Interventional

Mindfulness Engaged Neurostimulation for Depression

NCT06399406
View directory record Official record
Conditions
Depression, Treatment Resistant Depression, Major Depressive Disorder, Depressive Disorder
Interventions
Medi-TBS
Combination Product
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 65 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Oct 5, 2026, 7:50 PM EDT
Recruiting Not applicable Interventional

Treatment of Borderline Personality Disorder With rTMS

NCT07197502
View directory record Official record
Conditions
Borderline Personality Disorder, Borderline Personality, BPD - Borderline Personality Disorder
Interventions
Transcranial Magnetic Stimulation (TMS)
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 5, 2026, 7:50 PM EDT
Recruiting Not applicable Interventional

Brain Stimulation and Cognitive Training for MCI

NCT07526740
View directory record Official record
Conditions
Mild Cognitive Impairment (MCI), Mild Neurocognitive Disorder, Neurocognitive Disorders, Cognitive Dysfunction, Cognition Disorders
Interventions
Accelerated iTBS, Computerized Cognitive Training, Sham Computerized Cognitive Training
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
60 Years to 85 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 5, 2026, 7:50 PM EDT