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ClinicalTrials.gov public records Last synced Sep 25, 2026, 11:04 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Prehabilitation intervention Clear all
Recruiting Not applicable Interventional

Prehabilitation Physical Therapy and Relaxation Intervention Program to Promote Resiliency and Operative Success Among Adults Receiving Lung Cancer Surgery, ROAR-LCS Trial

NCT07584239
View directory record Official record
Conditions
Resectable Lung Non-Small Cell Carcinoma
Interventions
Biospecimen Collection, Exercise Intervention, Internet-Based Intervention, Physical Therapy, Relaxation Technique, Survey Administration, Text Message-Based Navigation Intervention
Procedure · Other · Behavioral
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated May 25, 2026 · Synced Sep 25, 2026, 11:04 PM EDT
Completed Not applicable Interventional Results available

Multi-Component Prehabilitation for Major Elective Surgery

NCT05752474
View directory record Official record
Conditions
Frailty, Functional Recovery, Prehabilitation
Interventions
Exercise, Nutrition, Meditation, Cognitive Behavioral Intervention
Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
65 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Sep 25, 2026, 11:04 PM EDT
Completed Not applicable Interventional

Prehabilitation for Pelvic Cancer: Changes in Setup Variability

NCT03242538
View directory record Official record
Conditions
Pelvic Cancer
Interventions
Pelvic Exercise
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
21 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 10, 2019 · Synced Sep 25, 2026, 11:04 PM EDT
Completed Not applicable Interventional

Prehabilitation for Patients Undergoing Transcatheter Aortic Valve Replacement

NCT03107897
View directory record Official record
Conditions
Aortic Valve Stenosis
Interventions
Pre-habilitation
Other
Lead sponsor
WellSpan Health
Other
Eligibility
Not listed
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
York, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 8, 2023 · Synced Sep 25, 2026, 11:04 PM EDT
Completed Not applicable Interventional Results available

Piloting Prehabilitation Before Abdominal Surgery

NCT03040336
View directory record Official record
Conditions
Frailty
Interventions
Prehabilitation
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 9, 2020 · Synced Sep 25, 2026, 11:04 PM EDT
Active, not recruiting Phase 1Phase 2 Interventional

Prehabilitation for EOC, Fallopian Tube, Primary Peritoneal Carcinoma and Pancreatic Cancer w/ NACT

NCT06412510
View directory record Official record
Conditions
Ovarian Cancer, Epithelial Ovarian Cancer, Pancreatic Adenocarcinoma
Interventions
Prehabilitation
Other
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
65 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Sep 25, 2026, 11:04 PM EDT
Not listed Not applicable Interventional

VR for Surgical Prehabilitation and Rehabilitation

NCT06334380
View directory record Official record
Conditions
Breast Cancer, Frailty, Surgery
Interventions
Virtual Reality Modules Only, Virtual Reality Modules + Live Physical Therapist Support
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Apr 24, 2024 · Synced Sep 25, 2026, 11:04 PM EDT
Completed Not applicable Interventional

An Exercise Prehabilitation Intervention for Improving Mobility and Recovery Outcomes in Patients Undergoing Head and Neck Cancer Surgery

NCT06079697
View directory record Official record
Conditions
Head and Neck Carcinoma
Interventions
Electronic Health Record Review, Exercise Intervention, Medical Device Usage and Evaluation, Survey Administration
Other
Lead sponsor
OHSU Knight Cancer Institute
Other
Eligibility
18 Years to 89 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Dec 11, 2025 · Synced Sep 25, 2026, 11:04 PM EDT
Completed No phase listed Observational

Identifying Perceived Barriers and Facilitators Toward a Liver Transplantation Prehabilitation

NCT04854564
View directory record Official record
Conditions
Liver Transplant; Complications
Interventions
Prehabilitation intervention, Caregiver intervention
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 74 Years
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 30, 2023 · Synced Sep 25, 2026, 11:04 PM EDT
Recruiting Phase 2 Interventional

Comprehensive Multimodal Prehabilitation Alone or With Neoadjuvant Therapy Before Major Cancer Surgery

NCT07050771
View directory record Official record
Conditions
Hepatopancreaticobiliary (HPB) Malignancy, Ovarian Cancer (OvCa), Kidney Cancers, Bladder Cancer
Interventions
Comprehensive multimodal prehabilitation (CMMP)
Other
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years and older
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Sep 25, 2026, 11:04 PM EDT
Completed Not applicable Interventional

Prehabilitation During the Neoadjuvant Window of Opportunity in Older Women With Ovarian Cancer

NCT05092763
View directory record Official record
Conditions
Ovarian Cancer, Neoadjuvant Chemotherapy, Prehabilitation
Interventions
FIT4SURGERY, Healthy Lifestyle Control
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
60 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 28, 2025 · Synced Sep 25, 2026, 11:04 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Effect of Prehabilitation on Surgical Outcomes of Abdominally-based Plastic Surgery Procedures

NCT04787874
View directory record Official record
Conditions
Ventral Hernia, Panniculus, Abdominoplasty, Flap Reconstruction
Interventions
Prehabilitation Program
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
19 Years and older
Enrollment
520 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
2
States / cities
San Jose, California • Stanford, California
Source: ClinicalTrials.gov public record
Updated Dec 14, 2021 · Synced Sep 25, 2026, 11:04 PM EDT
Recruiting Not applicable Interventional

Prehabilitation and Rehabilitation in PAD

NCT06566976
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Exercise Intervention, VAPAHCS Rehabilitation Core Components
Other
Lead sponsor
Palo Alto Veterans Institute for Research
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Aug 21, 2024 · Synced Sep 25, 2026, 11:04 PM EDT
Completed Not applicable Interventional

Prehabilitation to Improve Functional and Clinical Outcomes in Patients With Aortic Stenosis

NCT02597985
View directory record Official record
Conditions
Aortic Stenosis
Interventions
Prehabilitation, Usual Care
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
60 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 22, 2021 · Synced Sep 25, 2026, 11:04 PM EDT
Recruiting Not applicable Interventional

Prehabilitation in High-risk Oncologic Surgery

NCT07638410
View directory record Official record
Conditions
Pancreatic Cancer, Colo-rectal Cancer, Gastric Cancer, Esophageal Cancer, Bladder Cancer, Ovarian Cancer, Abdominal Surgery Complications
Interventions
Multidisciplinary Prehabilitation Program
Behavioral
Lead sponsor
Fox Chase Cancer Center
Other
Eligibility
18 Years and older
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 20, 2026 · Synced Sep 25, 2026, 11:04 PM EDT
Terminated Not applicable Interventional

The Impact of Prehabilitation

NCT06181253
View directory record Official record
Conditions
Post Operative Complications
Interventions
Preoperative education, Moderate aerobic exercise, Text messages, Pedometer
Other · Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
21 Years to 65 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Sep 25, 2026, 11:04 PM EDT
Recruiting Not applicable Interventional

Prehabilitation Exercise Training in Multiple Myeloma Patients Undergoing Autologous Stem Cell Transplantation

NCT05706766
View directory record Official record
Conditions
Multiple Myeloma, Stem Cell Transplant Complications
Interventions
PARE, Waitlist Control Group
Behavioral
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Sep 25, 2026, 11:04 PM EDT
Recruiting Not applicable Interventional

Prehabilitation for Kidney Transplant Candidates

NCT06886256
View directory record Official record
Conditions
Kidney Transplantation, Frailty, Chronic Kidney Insufficiency
Interventions
Polar H10 Heart Rate Monitor, Empatica EmbracePlus, Apple Watch Ultra 2
Device
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
55 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 17, 2025 · Synced Sep 25, 2026, 11:04 PM EDT
Completed Not applicable Interventional

Esophageal Cancer Multimodal Prehabilitation Study

NCT06027515
View directory record Official record
Conditions
Esophageal Cancer, Esophageal Neoplasms
Interventions
Prehabilitation Program
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
65 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Sep 25, 2026, 11:04 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Does Undergoing a Prehabilitation Protocol Aimed at Optimizing Scapulothoracic Mobility and Strengthening Improve Internal Rotation After Reverse Shoulder Arthroplasty?

NCT07145957
View directory record Official record
Conditions
Primary Reverse Total Shoulder Arthroplasty
Interventions
Prehabilitation
Other
Lead sponsor
University of Florida
Other
Eligibility
40 Years to 80 Years
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Sep 25, 2026, 11:04 PM EDT
Completed Not applicable Interventional

Prehabilitation in Pancreatic Surgery

NCT03688867
View directory record Official record
Conditions
Pancreatic Resection, Preoperative Frailty
Interventions
Prehabilitation regimen
Behavioral
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
19 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 30, 2023 · Synced Sep 25, 2026, 11:04 PM EDT
Recruiting Not applicable Interventional

Individualized Prehabilitation for Enhancing Recovery and Surgical Outcomes in Patients Undergoing Radiotherapy and Surgery for Soft Tissue Sarcoma

NCT05526417
View directory record Official record
Conditions
Soft Tissue Sarcoma, Stage I Soft Tissue Sarcoma of the Trunk and Extremities, Stage II Soft Tissue Sarcoma of the Trunk and Extremities, Stage III Soft Tissue Sarcoma of the Trunk and Extremities
Interventions
Computed Tomography, Educational Intervention, Magnetic Resonance Imaging, Physical Therapy, Questionnaire Administration, Telemedicine
Procedure · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Jun 21, 2026 · Synced Sep 25, 2026, 11:04 PM EDT
Completed Not applicable Interventional

Prehabilitation to Revolutionize Oncology: Telehealth Exercise for Cognitive Triumphs (The PROTECT Trial)

NCT05716542
View directory record Official record
Conditions
Breast Cancer, Cancer of the Breast
Interventions
Physical Activity Intervention
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older · Female only
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 27, 2025 · Synced Sep 25, 2026, 11:04 PM EDT
Terminated Not applicable Interventional

Remote Telemonitoring to Improve Prehabilitation and Surgical Outcomes of Patients Undergoing Elective Abdominal Surgery

NCT03706963
View directory record Official record
Conditions
Abdominal Surgery
Interventions
Phone Call
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
169 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 11, 2022 · Synced Sep 25, 2026, 11:04 PM EDT