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ClinicalTrials.gov public records Last synced Oct 31, 2026, 12:26 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 337–360 of 389 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Present Pain Intensity Clear all
Completed Not applicable Interventional Results available

Bronx MBCT-Migraine

NCT02443519
View directory record Official record
Conditions
Migraine
Interventions
MBCT for Migraine
Behavioral
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Oct 12, 2020 · Synced Oct 31, 2026, 12:26 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

LIFU for Anxiety Management

NCT05839847
View directory record Official record
Conditions
Anxiety
Interventions
Low-intensity focused ultrasound, Low-intensity focused ultrasound - sham
Device
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
18 Years to 65 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Oct 31, 2026, 12:26 PM EDT
Recruiting No phase listed Observational

The Prevalence of Directional Preference in the Lumbar Stenosis Population

NCT07007663
View directory record Official record
Conditions
Lumbar Stenosis
Interventions
Not listed
Lead sponsor
NYU Langone Health
Other
Eligibility
48 Years and older
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Lake Success, New York
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Oct 31, 2026, 12:26 PM EDT
Terminated Not applicable Interventional

Feasibility of Telehealth Mindfulness for Back Pain in the Emergency Department

NCT04783532
View directory record Official record
Conditions
Low Back Pain, Back Pain, Pain, Chronic Low-back Pain
Interventions
Telehealth Mindfulness Program
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 31, 2022 · Synced Oct 31, 2026, 12:26 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Football Players Health Study In Person Assessments Study

NCT03866564
View directory record Official record
Conditions
Cardiac Dysfunction, Neurocognitive Disease, Chronic Pain, Sleep Apnea
Interventions
Echocardiography, Neuropsychological Testing, Quantitative Sensory Testing, Nocturnal Polysomnography
Diagnostic Test
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
24 Years to 55 Years · Male only
Enrollment
111 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 8, 2024 · Synced Oct 31, 2026, 12:26 PM EDT
Active, not recruiting Not applicable Interventional Results available

Sickle Cell Disease (SCD) Bone Pain Study

NCT05283148
View directory record Official record
Conditions
Sickle Cell Disease, Sickle Cell Anemia, Low Bone Density, Osteoporosis, Osteopenia, Vertebral Fracture, Vertebral Compression, Osteonecrosis, Ischemic Necrosis, Avascular Necrosis
Interventions
Dual-energy X-ray absorptiometry, Vertebral fracture analysis, Adult Sickle Cell Quality of Life Measurement System pain impact questionnaire
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 80 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Sep 23, 2026 · Synced Oct 31, 2026, 12:26 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pre-op Cognitive Behavior Therapy to Decrease Chronic Post-Surgical Pain in TKA

NCT04814992
View directory record Official record
Conditions
Chronic Post-Surgical Pain
Interventions
Computer-Assisted Preoperative CBT Intervention (PAINTrainer)
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
22 Years and older
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
4
States / cities
Philadelphia, Pennsylvania • Radnor, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 17, 2024 · Synced Oct 31, 2026, 12:26 PM EDT
Completed No phase listed Observational

Use of Strattice Mesh in Paraesophageal Hernia Surgery

NCT01678157
View directory record Official record
Conditions
Esophageal Hernia, Hernia, Esophageal, Hernia, Paraesophageal, Hiatal Hernia, Paraesophageal Hiatal Hernia, Sliding Esophageal Hernia, Sliding Hiatal Hernia
Interventions
Not listed
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 6, 2023 · Synced Oct 31, 2026, 12:26 PM EDT
Completed Not applicable Interventional Results available

Innovation in the Treatment of Persistent Pain in Adults With NF1: Implementation of the iCanCope Mobile Application- Clinical Trial

NCT04561765
View directory record Official record
Conditions
Neurofibromatosis 1, Chronic Pain
Interventions
iCanCope, iCanCope+Contingency Management
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years to 72 Years
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 30, 2025 · Synced Oct 31, 2026, 12:26 PM EDT
Recruiting Not applicable Interventional

Helping Lupus Patients Manage Fibromyalgia Symptoms Through Emotional Awareness and Expression Therapy (EAET)

NCT07282392
View directory record Official record
Conditions
Lupus, Fibromyalgia (FM), Chronic Widespread Pain
Interventions
Emotional Awareness and Expression Therapy (EAET)
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Dec 29, 2025 · Synced Oct 31, 2026, 12:26 PM EDT
Recruiting No phase listed Observational

Virtual Reality (VR) for Interventional Radiology (IR) Procedures

NCT07427862
View directory record Official record
Conditions
Pain, Procedural Anxiety
Interventions
Meta Oculus Quest Pro, Pico 4, Pico G3
Device
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
8 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Oct 31, 2026, 12:26 PM EDT
Completed No phase listed Observational

Smartphone Twelve Lead Electrocardiogram Utility In ST-Elevation Myocardial Infarction

NCT03037229
View directory record Official record
Conditions
STEMI
Interventions
Smartphone ECG, Standard 12-lead ECG
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 7, 2018 · Synced Oct 31, 2026, 12:26 PM EDT
Completed Phase 2 Interventional Results available

Clonidine Versus Adenosine to Treat Neuropathic Pain

NCT00349921
View directory record Official record
Conditions
Pain
Interventions
clonidine, adenosine, placebo
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
Not listed
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
2
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 10, 2018 · Synced Oct 31, 2026, 12:26 PM EDT
Recruiting Not applicable Interventional

The Use of AR / VR in Patients Presenting to the ED With Renal Colic

NCT07070401
View directory record Official record
Conditions
Renal Colic, Kidney Stones, Urolithiasis, Hypocitraturia
Interventions
Commercial AR/VR Headset with Calming App, Pharmacologic Standard of Care Alone
Device · Other
Lead sponsor
Community Medical Center, Toms River, NJ
Other
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Toms River, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 17, 2025 · Synced Oct 31, 2026, 12:26 PM EDT
Completed No phase listed Observational

Cervical Paraspinal Muscle Twitching and Cervical Facet Radiofrequency Ablation Outcomes

NCT05450679
View directory record Official record
Conditions
Cervical Facet Joint Pain, Chronic Pain, Neck Pain
Interventions
Cervical Radiofrequency Ablation (RFA)
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 31, 2026, 12:26 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Virtual Reality Analgesia in Labor: The VRAIL Pilot Study

NCT02926469
View directory record Official record
Conditions
Labor Pain
Interventions
Virtual Reality
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 1, 2018 · Synced Oct 31, 2026, 12:26 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

VR to Reduce Pain/Anxiety During IV Starts

NCT04942561
View directory record Official record
Conditions
Radiology
Interventions
Samsung Gear VR, Merge VR
Device
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
10 Years to 21 Years
Enrollment
107 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 1, 2021 · Synced Oct 31, 2026, 12:26 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Photobiomodulation and Tooth Analgesia

NCT06691269
View directory record Official record
Conditions
Dental Anaesthesia, Dental Pain, Dental Analgesia
Interventions
Photobiomodulation, Topical Benzocaine, Local Anesthesia
Device · Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
6 Years to 12 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Oct 31, 2026, 12:26 PM EDT
Completed Phase 3 Interventional Results available

To Study Generic Diclofenac Sodium Topical Gel 1% in the Treatment of Osteoarthritis of the Knee (Degenerative Joint Disease Presented as Joint Pain, Stiffness, Swelling and Restricted Motion).

NCT02596451
View directory record Official record
Conditions
Osteoarthritis
Interventions
Diclofenac Sodium gel, 1%, Voltaren® Gel, Placebo
Drug
Lead sponsor
Glenmark Pharmaceuticals Ltd. India
Industry
Eligibility
35 Years and older
Enrollment
1,164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
44
States / cities
Mesa, Arizona • Anaheim, California • Canoga Park, California + 32 more
Source: ClinicalTrials.gov public record
Updated Jun 28, 2017 · Synced Oct 31, 2026, 12:26 PM EDT
Recruiting Not applicable Interventional

A Multi-Site Feasibility Trial of Embedded Emergency Department Physical Therapy

NCT07224945
View directory record Official record
Conditions
Low Back Pain
Interventions
Embedded Emergency Department Physical Therapy, Usual Care
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Chicago, Illinois • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Oct 31, 2026, 12:26 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Non-intrusive Detection of Temporary Neurologic Impairment by Opioids

NCT05489601
View directory record Official record
Conditions
Neurologic Impairment by Opioids
Interventions
Oxycodone
Drug
Lead sponsor
Zxerex Corporation
Industry
Eligibility
21 Years to 59 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 5, 2022 · Synced Oct 31, 2026, 12:26 PM EDT
Completed Not applicable Interventional

A Novel Therapeutic Approach to Treat Chronic Pelvic Pain

NCT05467241
View directory record Official record
Conditions
Chronic Pelvic Pain
Interventions
Self-induced therapeutic tremor (SITT) combined with mindfulness
Behavioral
Lead sponsor
University of Tennessee Graduate School of Medicine
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 20, 2022 · Synced Oct 31, 2026, 12:26 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Social Presence and Perception in Virtual Reality on Pain (SPP)

NCT05335057
View directory record Official record
Conditions
Pain Threshold
Interventions
VR Close Other, VR Alone, VR Stranger, Video Close Other
Behavioral
Lead sponsor
Cornell University
Other
Eligibility
18 Years and older
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Ithaca, New York
Source: ClinicalTrials.gov public record
Updated Aug 23, 2024 · Synced Oct 31, 2026, 12:26 PM EDT
Completed No phase listed Observational

Magnetocardiography Using a Novel Analysis System (Cardioflux) in the Evaluation of Emergency Department Observation Unit Chest Pain Patients

NCT03255772
View directory record Official record
Conditions
Acute Coronary Syndrome, Myocardial Infarction
Interventions
Magnetocardiography
Diagnostic Test
Lead sponsor
Genetesis Inc.
Industry
Eligibility
18 Years and older
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 28, 2022 · Synced Oct 31, 2026, 12:26 PM EDT