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ClinicalTrials.gov public records Last synced Oct 31, 2026, 1:16 PM EDT

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Showing 361–384 of 389 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Present Pain Intensity Clear all
Completed Not applicable Interventional Results available

Pain, Sexual Dysfunction, and Depression in Hemodialysis Patients

NCT00692419
View directory record Official record
Conditions
End Stage Renal Disease, Sexual Dysfunction, Physiological, Pain, Depression
Interventions
Symptom management nurse intervention, Feedback intervention
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
315 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 27, 2015 · Synced Oct 31, 2026, 1:16 PM EDT
Completed No phase listed Observational

Utility of a Molecular Personalized Coronary Gene Expression Test (Corus CAD or ASGES) on Cardiology Practice Pattern

NCT01251302
View directory record Official record
Conditions
Angina Pectoris, Coronary Artery Disease, Chest Pain, Cardiovascular Diseases, Coronary Heart Disease, CAD, CVD, CHD
Interventions
Corus CAD (ASGES)
Diagnostic Test
Lead sponsor
CardioDx
Industry
Eligibility
21 Years to 99 Years
Enrollment
171 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 31, 2019 · Synced Oct 31, 2026, 1:16 PM EDT
Completed Not applicable Interventional

Emergency Department Digital Pain Self-Management Intervention to Improve Acute Low Back Pain Outcomes

NCT06360341
View directory record Official record
Conditions
Low Back Pain, Mechanical, Acute Pain
Interventions
Emergency Department Digital Pain Self-Management Intervention (EDPSI), Routine Discharge Care
Behavioral · Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 27, 2025 · Synced Oct 31, 2026, 1:16 PM EDT
Completed Not applicable Interventional Results available

Jointstrong Intervention for Juvenile Arthritis

NCT01166750
View directory record Official record
Conditions
Juvenile Arthritis
Interventions
CD-ROM, Wait-list Control Group
Behavioral
Lead sponsor
Michael Rapoff, Ph.D.
Other
Eligibility
8 Years to 12 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated May 31, 2013 · Synced Oct 31, 2026, 1:16 PM EDT
Recruiting No phase listed Observational

Biopsychosocial Risk Influences on the Development and Generation of Early-Onset Chronic Pain

NCT07602595
View directory record Official record
Conditions
Juvenile Idiopathic Arthritis (JIA), Fibromyalgia, Lupus, Scoliosis, Pectus Excavatum, Chronic Pain, Musculoskeletal Pain
Interventions
Not applicable- observational study
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
14 Years to 26 Years
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 31, 2026, 1:16 PM EDT
Active, not recruiting Phase 4 Interventional Accepts healthy volunteers

Analgesic Techniques for Rib Fractures

NCT06519929
View directory record Official record
Conditions
Rib Fractures
Interventions
ESP block with catheter using ropivacaine (bolus followed by continuous infusion), Lidocaine bolus (1 mg/kg) and infusion starting at 1 mg/kg/h
Procedure · Drug
Lead sponsor
Thomas Jefferson University
Other
Eligibility
55 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 9, 2025 · Synced Oct 31, 2026, 1:16 PM EDT
Completed No phase listed Observational

Axicabtagene Ciloleucel:Neurocognitive and Patient-Reported Outcomes

NCT04319237
View directory record Official record
Conditions
Diffuse Large B Cell Lymphoma, Transformed Lymphoma
Interventions
Handgrip strength test, Neuropsychological Assessment - Wechsler Test of Adult Reading (WTAR), Neuropsychological Assessment - Repeatable Battery for the Assessment of Status (RBANS), Neuropsychological Assessment - Color Trails, Neuropsychological Assessment -Stroop Color and Word Test, Patient Reported Outcomes Measurement Information System-29 (PROMIS-29) Questionnaire, European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire, Quality of Life (EQ-5D-5L) Questionnaire, PROMIS Cognitive Function 4a Questionnaire, Comprehensive Score for Financial Toxicity (COST) measure
Other · Behavioral
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Mar 2, 2026 · Synced Oct 31, 2026, 1:16 PM EDT
Recruiting Phase 2 Interventional

MDMA-Assisted Therapy for Veterans With Moderate to Severe Post Traumatic Stress Disorder

NCT05790239
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
3,4-methylenedioxymethamphetamine, d-amphetamine, Therapy
Drug · Behavioral
Lead sponsor
Stephen Robert Marder
Federal
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 31, 2026, 1:16 PM EDT
Enrolling by invitation Phase 4 Interventional

A Study of Intravenous Acetaminophen for Small Bowel Obstruction

NCT05878015
View directory record Official record
Conditions
Small Bowel Obstruction
Interventions
Acetaminophen
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Oct 31, 2026, 1:16 PM EDT
Completed Not applicable Interventional

Treating Pain With Acceptance and Commitment Therapy Trial

NCT03666455
View directory record Official record
Conditions
Acceptance and Commitment Therapy, Chronic Pain, Opioid Use
Interventions
Acceptance and Commitment Therapy
Behavioral
Lead sponsor
University of New Mexico
Other
Eligibility
21 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
4
States / cities
Kansas City, Kansas • Lexington, Kentucky • Albuquerque, New Mexico + 1 more
Source: ClinicalTrials.gov public record
Updated May 24, 2023 · Synced Oct 31, 2026, 1:16 PM EDT
Completed Not applicable Interventional

Mechanisms of Palmitoylethanolamide (PEA) to Alter Pain Sensitivity in Knee Osteoarthritis

NCT05406726
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
palmitoylethanolamide, Placebo
Dietary Supplement
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
40 Years to 80 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 5, 2024 · Synced Oct 31, 2026, 1:16 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Safety and Tolerability of the Derma Vax(Trademark) Clinical Intradermal Electroporation System in Healthy Subjects

NCT01324843
View directory record Official record
Conditions
Intradermal Electroporation
Interventions
EMLA Cream, Aveeno Daily Moist, Derma Vax, Intradermal Electroporation, Visual Analogue Scale, Present Pain Intensity, McGill Pain Questionnaire, Skin Assessment
Drug · Device · Procedure
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
18 Years to 55 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 31, 2026, 1:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Brief Thermal and Electrical Pain (Four Study Days)

NCT00682682
View directory record Official record
Conditions
Pain
Interventions
Virtual Reality video distraction, Virtual Reality video game
Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 45 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 13, 2011 · Synced Oct 31, 2026, 1:16 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Study to Identify the Genetic Variations Associated With Phantom Limb Pain

NCT01462448
View directory record Official record
Conditions
Phantom Limb
Interventions
Blood Draw
Procedure
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
18 Years and older
Enrollment
726 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2023
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 12, 2025 · Synced Oct 31, 2026, 1:16 PM EDT
Completed Not applicable Interventional Results available

LiveWell: Adapted DBT Skills Training for Metastatic Lung Cancer

NCT06464562
View directory record Official record
Conditions
Cancer Metastatic to Lung
Interventions
LiveWell: Adapted Dialectical Behavioral Therapy Skills Training
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Oct 31, 2026, 1:16 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

ARPA-H Smart Band-Aid to Measure Chronic Pain in Women

NCT06994988
View directory record Official record
Conditions
Chronic Pain
Interventions
A-Band (Smart Band-Aid), Empatica Smartwatch, Questionnaires: Hospital Anxiety & Depression Scale, Central Sensitization Inventory, Pain Catastrophizing Scale, Somatic Symptom Scale-8, Pain Self-Efficacy Questionnaire-10, Athens Insomnia Scale
Device · Combination Product · Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
115 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Chicago, Illinois • Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 31, 2026, 1:16 PM EDT
Terminated Not applicable Interventional Results available

Single-incision Laparoscopic (SILS) Versus Conventional Laparoscopic Appendectomy for the Treatment of Acute Appendicitis

NCT00997516
View directory record Official record
Conditions
Appendicitis
Interventions
SILS appendectomy, conventional laparoscopic appendectomy
Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
2
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 22, 2014 · Synced Oct 31, 2026, 1:16 PM EDT
Completed Not applicable Interventional

A Wheelchair Propulsion Training Program

NCT04009187
View directory record Official record
Conditions
Spinal Cord Injuries, Multiple Sclerosis, Amputation, Spina Bifida
Interventions
In-person wheelchair propulsion training program, 30-minute education session
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 28, 2025 · Synced Oct 31, 2026, 1:16 PM EDT
Completed Not applicable Interventional

A Comparison of Scar Infiltration, Scar Deactivation, and Standard of Care for the Treatment of Chronic, Post-Surgical Pain After Cesarean Section

NCT03936309
View directory record Official record
Conditions
Scar, Cesarean Section; Dehiscence
Interventions
Scar Deactivation Surface Release Technique protocol, Scar Infiltration with 0.25-1% Lidocaine, Physical therapy
Other
Lead sponsor
Jennifer Loomis
Federal
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Scott Air Force Base, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 9, 2025 · Synced Oct 31, 2026, 1:16 PM EDT
Completed Not applicable Interventional Results available

Parent Nurse Controlled Analgesic in Pediatric Patients With Developmental Delay

NCT00743730
View directory record Official record
Conditions
Post Operative Pain
Interventions
Pain and standard side effect management for PNCA with basal method., Pain and standard side effect management with PNCA without basal, Pain and standard side effect management with IV on an as needed basis method.
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
4 Years to 18 Years
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 28, 2019 · Synced Oct 31, 2026, 1:16 PM EDT
Completed Not applicable Interventional

Whole Health Empowerment for Endotypes of Lupus: Improving Quality of Life in SLE

NCT06720584
View directory record Official record
Conditions
Systemic Lupus Erythematosus (SLE)
Interventions
Health coach-led, online support program for people living with lupus
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Oct 31, 2026, 1:16 PM EDT
Completed No phase listed Observational

H. Pylori Testing for Patients With Non-specific Upper Abdominal Pain in the Emergency Department

NCT01376414
View directory record Official record
Conditions
Gastritis, Peptic Ulcer, Peptic Ulcer Perforation, Stomach Ulcer
Interventions
Urea Breath Test (UBT) for H. pylori infection
Other
Lead sponsor
George Washington University
Other
Eligibility
18 Years and older
Enrollment
212 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
2
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Aug 26, 2016 · Synced Oct 31, 2026, 1:16 PM EDT
Withdrawn Phase 4 Interventional

Volume vs Concentration: Quadratus Lumborum Blocks With High Volume/Low Concentration or Low Volume/ High Concentration in Nephrectomies

NCT04077398
View directory record Official record
Conditions
Analgesia, Postoperative Pain, Block
Interventions
Ropivacaine 0.5% Injectable Solution
Drug
Lead sponsor
Bruce Ben-David
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 16, 2021 · Synced Oct 31, 2026, 1:16 PM EDT
Completed Not applicable Interventional

Mindfulness Surgical Pain Outcomes

NCT05838443
View directory record Official record
Conditions
Post Surgical Pain, Surgery
Interventions
Self-directed mindfulness utilizing a multi-sensor EEG-supported device with neurofeedback-assisted and technology-supported meditation, Provider-directed mindfulness, Conventional Care
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
10 Years to 18 Years
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 12, 2024 · Synced Oct 31, 2026, 1:16 PM EDT