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ClinicalTrials.gov public records Last synced Oct 30, 2026, 11:35 PM EDT

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Showing 169–192 of 389 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Present Pain Intensity Clear all
Completed Not applicable Interventional

Physical Therapy Trial for Pelvic Pain

NCT00434343
View directory record Official record
Conditions
Interstitial Cystitis, Painful Bladder Syndrome, Chronic Prostatitis, Chronic Pelvic Pain Syndrome
Interventions
Global Therapeutic Massage (GTM), Myofascial physical therapy (MPT)
Other
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years and older
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
5
States / cities
Stanford, California • Chicago, Illinois • Maywood, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 12, 2022 · Synced Oct 30, 2026, 11:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study of Affect Induction for Lab Induced Pain in Healthy Undergraduates

NCT05619419
View directory record Official record
Conditions
Meditation, Pain, Mindfulness, Affect, Emotion Regulation
Interventions
Mindfulness-enhanced positive affect induction, Breathing Meditation
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 65 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 22, 2023 · Synced Oct 30, 2026, 11:35 PM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Addition of Clonidine to Ropivacaine in Adductor Canal Block

NCT03057015
View directory record Official record
Conditions
Postoperative Pain
Interventions
Clonidine, Placebo, Ropivacaine, Dexamethasone, Epinephrine
Drug
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated May 3, 2018 · Synced Oct 30, 2026, 11:35 PM EDT
Not listed Not applicable Interventional

A Study of the Impact of Genetic Testing on Clinical Decision Making and Patient Care

NCT02487888
View directory record Official record
Conditions
Pain, Chronic Pain, Mental Disorders, Cardiovascular Diseases, Diabetes Mellitus, Type 2, Arthritis
Interventions
Unblinded to Genetic Testing Results, Blinded to Genetic Testing Results
Other
Lead sponsor
Proove Bioscience, Inc.
Industry
Eligibility
18 Years and older
Enrollment
100,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
31
States / cities
Beverly Hills, California • Fresno, California • La Jolla, California + 23 more
Source: ClinicalTrials.gov public record
Updated Mar 30, 2016 · Synced Oct 30, 2026, 11:35 PM EDT
Completed No phase listed Observational

Usefulness of a 2-hour Delta Troponin-I During the ED Identification and Exclusion of Acute Myocardial Infarction

NCT02002546
View directory record Official record
Conditions
Acute Coronary Syndrome
Interventions
Not listed
Lead sponsor
Chattanooga-Hamilton County Hospital Authority
Other
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Chattanooga, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 24, 2018 · Synced Oct 30, 2026, 11:35 PM EDT
Completed Phase 2 Interventional Results available

Optimization of Spinal Manipulative Therapy Protocols

NCT02868034
View directory record Official record
Conditions
Low Back Pain
Interventions
SMT, Mobilizing Exercises, Activation Exercises, SMT extended
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 60 Years
Enrollment
273 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated May 17, 2023 · Synced Oct 30, 2026, 11:35 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

PET/MRI Imaging of Neuraxial Inflammation in Sciatica Patients

NCT02130271
View directory record Official record
Conditions
Sciatica
Interventions
Radioactive dye, PET/MRI, Blood draw
Drug · Radiation · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 16, 2019 · Synced Oct 30, 2026, 11:35 PM EDT
Completed Not applicable Interventional

Goal Oriented Activity for Latinos With Spine Pain

NCT05005416
View directory record Official record
Conditions
Low Back Pain, Neck Pain, Chronic Pain, Chronic Low-back Pain
Interventions
GOALS Intervention, Usual Care Physical Therapy
Behavioral
Lead sponsor
San Diego State University
Other
Eligibility
18 Years to 66 Years
Enrollment
138 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
2
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 10, 2025 · Synced Oct 30, 2026, 11:35 PM EDT
Completed Not applicable Interventional

Evaluation of Pain Neuroscience Education for Patients Who Experience Chronic Pain With Concurrent Opioid Dependence

NCT06442306
View directory record Official record
Conditions
Chronic Pain, Opioid Dependence
Interventions
Pain Neuroscience Education, General Health Education
Other
Lead sponsor
Wichita State University
Other
Eligibility
18 Years to 95 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 4, 2024 · Synced Oct 30, 2026, 11:35 PM EDT
Not listed Phase 3 Interventional

Local 5-Fluorouracil Injection for the Treatment of Chalazia: A Prospective, Comparative Study

NCT02025023
View directory record Official record
Conditions
Chalazion
Interventions
5-fluorouracil Injection, Triamcinolone Acetonide, Incision and Curettage, Triamcinolone Acetonide/5-fluorouracil mixture
Drug · Procedure
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2026
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 6, 2020 · Synced Oct 30, 2026, 11:35 PM EDT
Completed Phase 2 Interventional

Study to Assess the Safety and Efficacy of Benzocaine for Pain Relief in Children Presenting With Acute Otitis Media

NCT02092454
View directory record Official record
Conditions
Pain, Acute Otitis Media
Interventions
Benzocaine, Placebo
Drug
Lead sponsor
Otic Therapy, LLC
Industry
Eligibility
2 Months to 12 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
3
States / cities
Clearwater, Florida • Gresham, Oregon • Murray, Utah
Source: ClinicalTrials.gov public record
Updated May 25, 2015 · Synced Oct 30, 2026, 11:35 PM EDT
Suspended Not applicable Interventional

Feasibility and Preliminary Efficacy of Acceptance and Commitment Therapy (ACT) for Sleep Disturbances in Adults With Sickle Cell Disease (SCD)

NCT05457790
View directory record Official record
Conditions
Sickle Cell Disease, Sickle Cell Anemia, Insomnia, Sleeplessness, Transient Insomnia, Nonorganic Insomnia, Chronic Insomnia
Interventions
ACT Intervention, Waitlist
Behavioral
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years to 55 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 20, 2025 · Synced Oct 30, 2026, 11:35 PM EDT
Enrolling by invitation Not applicable Interventional

Comparing Two Moral Injury Treatments

NCT07710521
View directory record Official record
Conditions
Moral Injury
Interventions
Acceptance and Commitment Therapy for Moral Injury (ACT-MI), Present Centered Therapy for Moral Injury (PCT-MI)
Behavioral
Lead sponsor
VA Eastern Colorado Health Care System
Federal
Eligibility
18 Years to 89 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 30, 2026, 11:35 PM EDT
Completed Not applicable Interventional Results available

Music Therapy in Sickle Cell Transition Study

NCT02466555
View directory record Official record
Conditions
Sickle Cell Disease
Interventions
Music Therapy
Behavioral
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 23 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 13, 2019 · Synced Oct 30, 2026, 11:35 PM EDT
Completed Not applicable Interventional

Opioid and Pain Cognition

NCT04132609
View directory record Official record
Conditions
Pain
Interventions
Cognitive bias modification, Standard attentional bias
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 14, 2021 · Synced Oct 30, 2026, 11:35 PM EDT
Completed No phase listed Observational

Long Term Prognosis of MRI Diagnosed Partial Thickness Tears of the Rotator Cuff

NCT00779415
View directory record Official record
Conditions
Rotator Cuff Tear
Interventions
Not listed
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 27, 2015 · Synced Oct 30, 2026, 11:35 PM EDT
Completed Not applicable Interventional

Physical Therapy to Treat Chronic Pain in Survivors of Trauma

NCT03933189
View directory record Official record
Conditions
Chronic Pain, Disability Physical
Interventions
Physical Therapy
Other
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
South Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Sep 29, 2021 · Synced Oct 30, 2026, 11:35 PM EDT
Completed Not applicable Interventional

Predicting Analgesic Response to Acupuncture: A Practical Approach

NCT02890810
View directory record Official record
Conditions
Chronic Low Back Pain, Back Pain
Interventions
Real Acupuncture with Electrical Stimulation, Simulated Acupuncture with Electrical Stimulation
Other
Lead sponsor
Stanford University
Other
Eligibility
21 Years to 65 Years
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jan 25, 2021 · Synced Oct 30, 2026, 11:35 PM EDT
Completed Phase 1Phase 2 Interventional

Intravenous Gammaglobulin for Sickle Cell Pain Crises

NCT01757418
View directory record Official record
Conditions
Sickle Cell Disease, Pain
Interventions
Immune Globulin Intravenous (IVIG), Normal saline
Drug · Other
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
6 Years to 13 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2024
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Oct 30, 2026, 11:35 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Central Mechanisms of Chronic Pain and Fatigue Subtitle: Functional Imaging of Brain and Spinal Cord

NCT03075254
View directory record Official record
Conditions
Chronic Fatigue Syndrome, Fibromyalgia
Interventions
A Peltier for Sensory testing, functional magnetic resonance imaging for Brain Neuroimaging, fMRI for Spinal Cord Neuroimaging
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 70 Years
Enrollment
197 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2024
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 27, 2025 · Synced Oct 30, 2026, 11:35 PM EDT
Completed Phase 4 Interventional

Premedication for Less Invasive Surfactant Administration Study (PRELISA)

NCT05065424
View directory record Official record
Conditions
Respiratory Distress Syndrome, Newborn
Interventions
IV Atropine and Fentanyl Premedication Arm, IV Normal Saline Placebo Arm
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
0 Hours to 72 Hours
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced Oct 30, 2026, 11:35 PM EDT
Completed No phase listed Observational

Recovery Toolkits: Assessment of Pragmatic Behavioral Pain Medicine Delivered In Hospital After Surgery

NCT03828669
View directory record Official record
Conditions
Post Surgical Pain
Interventions
Recovery Toolkits
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
Not listed
Enrollment
649 participants
Timeline
2019 – 2021
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jul 8, 2021 · Synced Oct 30, 2026, 11:35 PM EDT
Completed Early Phase 1 Interventional

Feasibility of Near-infrared Spectroscopy to Measure Cortical Pain Pathway (Brain) Activation During Dry Needling

NCT04170803
View directory record Official record
Conditions
Shoulder Pain, Chronic Pain, Musculoskeletal Injury
Interventions
Dry Needling, Sham Dry Needling
Device · Other
Lead sponsor
Army-Baylor University Doctoral Program in Physical Therapy
Other
Eligibility
18 Years to 50 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 28, 2020 · Synced Oct 30, 2026, 11:35 PM EDT
Completed Not applicable Interventional

Safe and Effective Shoulder Exercise Training in Manual Wheelchair Users With SCI

NCT02777281
View directory record Official record
Conditions
Shoulder Pain, Spinal Cord Injury
Interventions
Shoulder pain and SCI, Shoulder pain and able bodies
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
21 Years to 60 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2023
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 5, 2024 · Synced Oct 30, 2026, 11:35 PM EDT