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Showing 1–24 of 43 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Present centered therapy for PTSD Clear all
Completed Phase 2Phase 3 Interventional

RECONsolidation of Traumatic Memories to ResOLve Post Traumatic Stress Disorder (RECONTROLPTSD)

NCT03827057
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Traumatic Brain Injury
Interventions
Reconsolidation of Traumatic Memories (RTM), Prolonged Exposure (PE)
Behavioral
Lead sponsor
Uniformed Services University of the Health Sciences
Federal
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 14, 2025 · Synced Sep 13, 2026, 8:56 AM EDT
Completed Not applicable Interventional Results available

Group Treatment for PTSD: A Randomized Clinical Trial With Veterans

NCT01544088
View directory record Official record
Conditions
PTSD
Interventions
Group Cognitive Behavioral Treatment (GCBT), Present Centered Group Treatment
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older · Male only
Enrollment
198 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
2
States / cities
Boston, Massachusetts • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 22, 2020 · Synced Sep 13, 2026, 8:56 AM EDT
Completed Not applicable Interventional Results available

Effectiveness of Peer-Delivered Trauma-Specific Treatment

NCT02081417
View directory record Official record
Conditions
Post-Traumatic Stress Disorder, Substance Use Disorders
Interventions
Seeking Safety
Behavioral
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years and older
Enrollment
291 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Española, New Mexico
Source: ClinicalTrials.gov public record
Updated Jun 9, 2019 · Synced Sep 13, 2026, 8:56 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

A Randomized Clinical Trial of Cognitive-Behavioral Treatment for Post-Traumatic Stress Disorders in Women

NCT00032617
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Prolonged Exposure, Present Centered Therapy
Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older · Female only
Enrollment
284 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2006
U.S. locations
13
States / cities
Denver, Colorado • Bay Pines, Florida • Decatur, Georgia + 10 more
Source: ClinicalTrials.gov public record
Updated Sep 23, 2010 · Synced Sep 13, 2026, 8:56 AM EDT
Completed Not applicable Interventional Results available

Psychosocial Rehabilitation After Moral Injury and Loss With Adaptive Disclosure

NCT03056157
View directory record Official record
Conditions
Post-traumatic Stress Disorder, Moral Injury, Traumatic Loss
Interventions
Adaptive Disclosure for Moral Injury and Loss, Present Centered Therapy
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
174 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
5
States / cities
San Diego, California • San Francisco, California • Boston, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 2, 2024 · Synced Sep 13, 2026, 8:56 AM EDT
Completed Not applicable Interventional Results available

A Multisite Randomized Controlled Trial of Mindfulness Meditation Therapy for PTSD

NCT01532999
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Mindfulness Based Stress Reduction, Present Centered Group Therapy
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
254 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
3
States / cities
Tuscaloosa, Alabama • Decatur, Georgia • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 7, 2015 · Synced Sep 13, 2026, 8:56 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Exposure Therapy for Chronic PTSD: Efficacy and Mechanisms

NCT00475241
View directory record Official record
Conditions
Combat Disorders, Posttraumatic Stress Disorder
Interventions
Prolonged Exposure therapy for PTSD, Present centered therapy for PTSD
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 14, 2019 · Synced Sep 13, 2026, 8:56 AM EDT
Recruiting Not applicable Interventional

Multifaceted Intervention to Restore Resilience and Overcome Risk

NCT06988787
View directory record Official record
Conditions
Military Sexual Trauma, Intimate Partner Violence, Brain Injury, Post Traumatic Stress Disorder
Interventions
webSTAIR, ExpoTx, PsychoEd
Behavioral · Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older · Female only
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 9, 2025 · Synced Sep 13, 2026, 8:56 AM EDT
Completed Not applicable Interventional

A Randomized Clinical Trial Testing the Effectiveness of Telemental Health for Suicidal Patients

NCT04844294
View directory record Official record
Conditions
Suicide, Suicidal Ideation, Suicide Attempt
Interventions
Brief Cognitive Behavioral Therapy (BCBT), Present-Centered Therapy (PCT)
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 4, 2025 · Synced Sep 13, 2026, 8:56 AM EDT
Completed Not applicable Interventional

A Comparison of Web-Prolonged Exposure (Web-PE) and Present-Centered Therapy (PCT) for PTSD Among Active-Duty Military Personnel

NCT02556645
View directory record Official record
Conditions
Posttraumatic Stress Disorders, Combat Disorders
Interventions
Web-PE Therapy, Therapist-Delivered Present-Centered Therapy
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
4
States / cities
Atlanta, Georgia • Philadelphia, Pennsylvania • Killeen, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 8, 2019 · Synced Sep 13, 2026, 8:56 AM EDT
Completed Not applicable Interventional

Mindfulness and Present Centered Therapies for PTSD: Efficacy and Mechanisms

NCT01347749
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Mindfulness & Compassion Meditation-based Exposure Therapy, Present Centered Therapy for PTSD
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
21 Years to 50 Years · Male only
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
2
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 5, 2019 · Synced Sep 13, 2026, 8:56 AM EDT
Completed Not applicable Interventional Results available

A Novel Posttraumatic Stress Disorder Treatment for Veterans With Moral Injury

NCT03764033
View directory record Official record
Conditions
Moral Injury
Interventions
Impact of Killing (IOK), Present Centered Therapy
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 82 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
3
States / cities
San Francisco, California • The Bronx, New York • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 19, 2025 · Synced Sep 13, 2026, 8:56 AM EDT
Completed Not applicable Interventional Results available

Treatment of PTSD in Residents of Battered Women's Shelters

NCT02398227
View directory record Official record
Conditions
PTSD
Interventions
HOPE, PCT
Behavioral
Lead sponsor
The University of Akron
Other
Eligibility
Female only
Enrollment
172 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Akron, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 9, 2018 · Synced Sep 13, 2026, 8:56 AM EDT
Completed Phase 3 Interventional Results available

Mantram Repetition Meditation for Veterans With PTSD

NCT01506323
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Mantram Repetition Program (MRP), Present Centered Therapy (PCT)
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
181 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
2
States / cities
San Diego, California • Bedford, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 1, 2015 · Synced Sep 13, 2026, 8:56 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Transcendental Meditation in Veterans and First Responders With PTSD

NCT05645042
View directory record Official record
Conditions
PTSD
Interventions
Transcendental Meditation (TM), Present Centered Therapy (PCT)
Behavioral
Lead sponsor
Research Foundation for Mental Hygiene, Inc.
Other
Eligibility
18 Years to 80 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
5
States / cities
La Jolla, California • Los Angeles, California • Palo Alto, California + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 8, 2025 · Synced Sep 13, 2026, 8:56 AM EDT
Enrolling by invitation Not applicable Interventional

Implementation of Innovative Treatment for Moral Injury Syndrome: A Hybrid Type 2 Study

NCT06230887
View directory record Official record
Conditions
Moral Injury Syndrome
Interventions
Building Spiritual Strength, Present Centered Group Therapy
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
5
States / cities
Little Rock, Arkansas • Decatur, Georgia • Augusta, Maine + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 19, 2026 · Synced Sep 13, 2026, 8:56 AM EDT
Completed Not applicable Interventional

Treatment of Post-Traumatic Stress Disorder (PTSD) and Chronic Pain After Traumatic Orthopedic Injury

NCT00957164
View directory record Official record
Conditions
Chronic Pain, Post-traumatic Stress Disorder
Interventions
Brief Prolonged Exposure Protocol, Chronic Pain Management Treatment, Self-Care
Behavioral
Lead sponsor
The University of Texas at Arlington
Other
Eligibility
18 Years to 70 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
4
States / cities
Arlington, Texas • Fort Sam Houston, Texas • Lackland Air Force Base, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 30, 2014 · Synced Sep 13, 2026, 8:56 AM EDT
Not yet recruiting Not applicable Interventional

The Development of a Transdiagnostic Intervention to Improve Social Functioning and Intimate Relationships Among Veterans

NCT06746727
View directory record Official record
Conditions
Alcohol Problems, Post-Traumatic Stress Disorder
Interventions
Acceptance and Commitment Therapy for Social Health, Achievement, and Relationship Effectiveness (ACT-SHARE)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2028 – 2030
U.S. locations
1
States / cities
Bedford, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 18, 2025 · Synced Sep 13, 2026, 8:56 AM EDT
Recruiting Not applicable Interventional

Reducing Dropout and Improving Outcomes From PTSD Therapy: When to Switch Therapies or Stay the Course

NCT06957067
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
CPT Skills, Cognitive Processing Therapy, Present Centered Therapy, Shared Decision Making, Measurement Based Care
Behavioral
Lead sponsor
United States Department of Defense
Federal
Eligibility
18 Years and older
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
4
States / cities
Phoenix, Arizona • New Orleans, Louisiana • Charleston, South Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Sep 13, 2026, 8:56 AM EDT
Completed Not applicable Interventional Results available

A Trial of Group Psychotherapy for Veterans and Military Personnel With Post Traumatic Stress Disorder (PTSD)

NCT00984698
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Depression, Insomnia Disorder
Interventions
Cognitive Behavioral Social Rhythm Group Therapy, Present Centered Group Therapy
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
2
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Mar 30, 2014 · Synced Sep 13, 2026, 8:56 AM EDT
Recruiting Not applicable Interventional

Manage Emotions to Reduce Aggression (MERA)

NCT04793776
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Aggression, Emotion Regulation
Interventions
Manage Emotions to Reduce Aggression, Present Centered Psychotherapy
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 64 Years
Enrollment
204 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
Tampa, Florida • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 7, 2026 · Synced Sep 13, 2026, 8:56 AM EDT
Completed Not applicable Interventional

Comparing Virtual Reality Therapy to Usual Treatment for PTSD

NCT00167804
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Virtual Reality Exposure
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 5, 2011 · Synced Sep 13, 2026, 8:56 AM EDT
Not yet recruiting Not applicable Interventional

Recovery-oriented Group Therapy for Veteran Men With Military Sexual Trauma

NCT06741202
View directory record Official record
Conditions
Sexual Trauma
Interventions
Men's MST Group, Present-Centered Group Therapy
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Male only
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
West Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 13, 2026, 8:56 AM EDT
Completed Not applicable Interventional

Psychotherapy for PTSD Among Veterans Also Receiving Drug or Alcohol Treatment

NCT04581434
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Substance Use Disorders
Interventions
Prolonged Exposure Therapy, Cognitive Processing Therapy, Present Centered Therapy
Behavioral
Lead sponsor
Center for Veterans Research and Education
Other
Eligibility
18 Years and older
Enrollment
426 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
14
States / cities
San Diego, California • Tampa, Florida • Atlanta, Georgia + 11 more
Source: ClinicalTrials.gov public record
Updated Jun 24, 2024 · Synced Sep 13, 2026, 8:56 AM EDT