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Conditions: Healthy
Interventions: Not listed
Lead sponsor: Philadelphia College of Osteopathic Medicine; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Suwanee, Georgia

Conditions: Pelvic Pain, Endometriosis
Interventions: Psychophysical assessment, Psychophysical assessments of experimental pain, Blood, urine and saliva samples, Biopsy and surgery-related data.; Other · Behavioral · Diagnostic Test + 1 more
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 12 Years to 45 Years · Female only
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2029
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Pain
Interventions: Forgionei-Barber pressure-pain stimulator, Concentric Exercise, isometric exercise; Device · Other
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years to 40 Years
Enrollment: 34 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Low Back Pain, Mechanical, Piriformis Syndrome, Somatic Dysfunction of Sacral Region (Finding)
Interventions: Strain-Counterstrain treatment of piriformis muscle; Other
Lead sponsor: Loma Linda University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Loma Linda, California

Conditions: Healthy, Pain
Interventions: Pain Inducing Massage, Pain Free Massage, Positive Expectation Instructional Set, Negative Expectation Instructional Set; Other
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 60 Years
Enrollment: 56 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Muscle Soreness, Muscle Weakness, Muscle Tenderness
Interventions: Kettlebell Swing, Isometric Hold, Control; Other
Lead sponsor: University of Central Florida; Other
Eligibility: 18 Years to 35 Years
Enrollment: 90 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Orlando, Florida

Conditions: Chronic Pancreatitis, Chronic Pain
Interventions: Quantitative Sensory Test 1, Quantitative Sensory Test 2, Quantitative Sensory Test 3; Diagnostic Test
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2028
U.S. locations: 3
States / cities: Indianapolis, Indiana • Baltimore, Maryland • Pittsburgh, Pennsylvania

Conditions: Chemotherapy-induced Peripheral Neuropathy
Interventions: Brief Pain Inventory, Hospital Anxiety and Depression Scale, Neuropathic Pain Symptom Inventory, Diode Laser fiber type Selective Stimulator, Quantitative sensory testing, Conditioned pain modulation efficiency, Spontaneous pain at baseline on 0-10 Numerical Rating Scale (NRS); Other · Procedure
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 42 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Temporomandibular Disorder (TMD)
Interventions: SPM Precursor-Enriched Marine Lipid Supplement, Medium-Chain Triglyceride Supplement; Dietary Supplement
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Lumbar Spine Injury, Pain
Interventions: Sidelying lumbar manipulation; Procedure
Lead sponsor: University of Mary; Other
Eligibility: 18 Years to 50 Years
Enrollment: 55 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023
U.S. locations: 1
States / cities: Bismarck, North Dakota

Conditions: Healthy
Interventions: Cold Water Immersion, Pain Inducing Stretch, Pain Free Stretch; Other
Lead sponsor: University of Central Florida; Other
Eligibility: 18 Years to 60 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023
U.S. locations: 1
States / cities: Orlando, Florida

Conditions: Musculoskeletal Pain, Fibromyalgia, Healthy Controls Group - Age and Sex-matched
Interventions: S-cone modulating visual stimulus, Equal Energy White Visual Stimulus, Green light visual stimulus (S-OFF), Evoked Pressure Pain Stimulus; Other
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Fibrous Dysplasia/McCune-Albright Syndrome
Interventions: MRI-based Neuroimaging, Non-contrast MRI, 18F-FDG-PET/CT, 18F-NaF-PET/CT; Diagnostic Test
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 10 Years to 45 Years
Enrollment: 37 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Chronic Pancreatitis, Chronic Pain
Interventions: Quantitative Sensory Test 1, Quantitative Sensory Test 2, Quantitative Sensory Test 3; Diagnostic Test
Lead sponsor: Anna Evans Phillips; Other
Eligibility: 18 Years and older
Enrollment: 500 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2031
U.S. locations: 2
States / cities: Baltimore, Maryland • Pittsburgh, Pennsylvania

Conditions: Myofascial Pain Syndromes
Interventions: The GRID foam roll; Device
Lead sponsor: California State University, Dominguez Hills; Other
Eligibility: 18 Years to 65 Years
Enrollment: 45 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016
U.S. locations: 1
States / cities: Carson, California

Conditions: Subarachnoid Hemorrhage, Aneurysmal, Delayed Cerebral Ischemia, Cerebral Vasospasm, Autonomic Nervous System Diseases
Interventions: Right-Sided Cervical Sympathetic Block at C6, Transcutaneous Auricular Vagal Nerve Stimulation (taVNS); Procedure · Device
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Low Back Pain
Interventions: Tabata Kettlebell Swing Workout, Control; Other
Lead sponsor: University of Central Florida; Other
Eligibility: 18 Years to 45 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014
U.S. locations: 1
States / cities: Orlando, Florida

Conditions: Migraine
Interventions: Thermal stimuli, Pressure stimuli, Pain ratings, Pressure pain thresholds (PPT), Conditioned pain modulation (CPM) response, PedMIDAS (Pediatric Migraine Disability Assessment), Hormonal assessment, Pubertal status; Device · Behavioral · Diagnostic Test + 1 more
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 11 Years to 15 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Segmental Dysfunction of the Lumbar Spine, Back Pain, Leg Pain
Interventions: Chiropractic, Exercise, Cryotherapy, Spinalator; Other · Device
Lead sponsor: Leach Chiropractic Clinic; Other
Eligibility: 18 Years to 75 Years
Enrollment: 98 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2023
U.S. locations: 1
States / cities: Starkville, Mississippi

Conditions: Pain
Interventions: Experimental Noxious Stimulus, Memory of Experimental Noxious Stimulus, Memory of Prior Significant Injury, Mental Challenge Test; Procedure · Behavioral
Lead sponsor: Mount St. Mary's College, Los Angeles, CA; Other
Eligibility: 18 Years to 60 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Sensitivity
Interventions: Intervention 1, Intervention 2, Intervention 3, Intervention 4 (sham); Device
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 40 Years
Enrollment: 22 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Anthropometrics: Height and Weight, Isometric Standing and Seated Plantarflexion, Calf Muscle Thickness, Achilles Tendon Length and Thickness, Myotonography of the Calf Musculature and Achilles Tendon, Pain Pressure Threshold of the Calf, Pain Scale, Endurance Calf Test, Dietary Analysis
Interventions: Collagen, Maltodextrin; Dietary Supplement
Lead sponsor: University of Central Florida; Other
Eligibility: 18 Years to 30 Years · Male only
Enrollment: 36 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 1
States / cities: Orlando, Florida

Conditions: Chronic Pancreatitis, Chronic Pain, Acute Recurrent Pancreatitis
Interventions: Quantitative Sensory Test 1, Quantitative Sensory Test 2, Quantitative Sensory Test 3; Diagnostic Test
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: 5 Years to 17 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Neck Pain Musculoskeletal, Chronic
Interventions: Spinal mobilization (SM) of the neck; Procedure
Lead sponsor: Azusa Pacific University; Other
Eligibility: 18 Years to 55 Years
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Azusa, California

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The Effect of Anxiety on Pain-pressure Threshold in a Healthy Population

Endometriosis Pain

Exercise-induced Hypoalgesia After Comparative Forms of Exercise

Strain-Counterstrain Treatment of Piriformis Pain

Mechanisms of Massage

Lumbosacral Muscle Sensitivity & Pressure Pain Threshold After Kettlebell Swings

Pancreatic Quantitative Sensory Testing (P-QST) to Predict Treatment Response for Pain in Chronic Pancreatitis

A New Method for Identifying Sensory Changes in Painful Chemotherapy-induced Peripheral Neuropathy (CIPN)

Marine Lipids Ease Painful TMD

Looking Beyond the Immediate Effects of Lumbar Spinal Manipulation Using Pain Pressure Threshold in Asymptomatic Individuals

Pain Modulatory Profiles in Stretching

Neural Mechanisms of Light Driven Analgesia

Pain in Fibrous Dysplasia

QST Study: Predicting Treatment Response in Chronic Pancreatitis Using Quantitative Sensory Testing

Does Self-myofascial Release With a Foam Roll Change Pressure Pain Thresholds in Lower Extremity Muscles

Noninvasive CA Monitoring Validation and Autonomic Modulation in Aneurysmal Subarachnoid Hemorrhage

Kettlebell Swings & Low Back Pressure Pain Threshold

Puberty, Sex Hormones and Pain Sensitivity in Adolescents With Migraine

Clinical Correlates of Pressure Pain Thresholds in Back and Leg Pain

The Effects of Pain and the Memory of Pain on Autonomic and Neuromuscular Function

Effects of Acute Intermittent Hypoxia on Sensory Function in Healthy Adults

Collagen Protein Versus Placebo on Muscle Recovery

Pancreatic Quantitative Sensory Testing (P-QST)

Association Between Conditioned Pain Modulation and the 4-week Response to Spinal Mobilization in Adults With Chronic Neck Pain