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ClinicalTrials.gov public records Last synced Oct 21, 2026, 12:31 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 190 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Pressure-flow study Clear all
Recruiting No phase listed Observational

Diagnostic Accuracy of ShuntCheck Compared to Radionuclide Shunt: Patency in Patients With Normal Pressure Hydrocephalus

NCT04309487
View directory record Official record
Conditions
Hydrocephalus, Normal Pressure
Interventions
ShuntCheck
Diagnostic Test
Lead sponsor
University of South Florida
Other
Eligibility
40 Years and older
Enrollment
20 participants
Timeline
2020 – 2027
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Oct 21, 2026, 12:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Role of Flavanols In Cardiovascular Function in Healthy Aging

NCT01395277
View directory record Official record
Conditions
Aging
Interventions
High Flavanol first then Low Flavanol, Low Flavanol first then High Flavanol
Dietary Supplement
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Aug 10, 2015 · Synced Oct 21, 2026, 12:31 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Assessing the Effects of a Topically Applied Cream to Clitoral Blood Flow

NCT01085981
View directory record Official record
Conditions
Female Sexual Dysfunction
Interventions
arginine 20%, nicotinamide .01%, niacin.1%, in LipodermPG 50%, Topical study cream, GRAS cream
Drug
Lead sponsor
East Suburban Ob Gyn
Other
Eligibility
25 Years to 60 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Monroeville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 12, 2010 · Synced Oct 21, 2026, 12:31 AM EDT
Completed Not applicable Interventional

Ischemic Preconditioning Claudication Study

NCT03511157
View directory record Official record
Conditions
Intermittent Claudication, Ischemia Vascular, Peripheral Arterial Disease, Peripheral Vascular Disease
Interventions
Ischemic Preconditioning, Control Group
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 80 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 14, 2022 · Synced Oct 21, 2026, 12:31 AM EDT
Completed No phase listed Observational

NOninVasive Intracranial prEssure From Transcranial doppLer Ultrasound Development of a Comprehensive Database of Multimodality Monitoring Signals for Brain-Injured Patients

NCT04548596
View directory record Official record
Conditions
Traumatic Brain Injury, Subarachnoid Hemorrhage, Intracerebral Hemorrhage, Liver Failure, Ischemic Stroke
Interventions
Transcranial Doppler
Diagnostic Test
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2025
U.S. locations
3
States / cities
Davis, California • San Francisco, California • Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 18, 2025 · Synced Oct 21, 2026, 12:31 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Migraine and CVD Risk in Women

NCT03081390
View directory record Official record
Conditions
Migraine
Interventions
Mixed meal tolerance testing, Skin conductance & cold pressor test, Flow-mediated dilation testing
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2026
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 21, 2026, 12:31 AM EDT
Completed Not applicable Interventional Results available

Feasibility Clinical Trial of the Cardio Flow Orbital Atherectomy System to Treat Peripheral Artery Disease (PAD)

NCT03365154
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Cardio Flow FreedomFlow™ Orbital Atherectomy System treatment, Balloon Angioplasty
Device
Lead sponsor
Cardio Flow, Inc.
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
2
States / cities
Gainesville, Florida • Saint Clair Shores, Michigan
Source: ClinicalTrials.gov public record
Updated May 20, 2021 · Synced Oct 21, 2026, 12:31 AM EDT
Terminated Phase 4 Interventional Results available

Tetra-NIRS Clinical Study

NCT00871975
View directory record Official record
Conditions
Lower Urinary Tract Symptoms, Overactive Bladder
Interventions
Urodynamics + TETRA - NIRS
Device
Lead sponsor
Laborie Medical Technologies Inc.
Industry
Eligibility
18 Years and older
Enrollment
155 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 19, 2016 · Synced Oct 21, 2026, 12:31 AM EDT
Not yet recruiting Not applicable Interventional

Mechanical Ventilator Adjustments and Patient Dyspnea

NCT07701850
View directory record Official record
Conditions
Respiratory Failure, Dyspnea During Mechanical Ventilation, Mechanical Ventilation
Interventions
Change to VC/AC, Change in Tidal Volume, Change in inspiratory flow, Change in PEEP, Change to PSV
Other
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Oct 21, 2026, 12:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Blood Flow Restriction With and Without Arginine on Physical Performance and Growth Hormone

NCT04079010
View directory record Official record
Conditions
Blood Flow Restriction, Growth Hormone, Strength Outcomes, Arginine
Interventions
BFR, Arginine, Placebo Pill
Procedure · Dietary Supplement
Lead sponsor
University of Mary Hardin-Baylor
Other
Eligibility
18 Years to 25 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Belton, Texas
Source: ClinicalTrials.gov public record
Updated Apr 2, 2020 · Synced Oct 21, 2026, 12:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Innovative Concussion Prevention Device

NCT02901028
View directory record Official record
Conditions
Concussion
Interventions
Laboratory testing, Blood and Urine Draws
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
18 Years to 25 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 15, 2016 · Synced Oct 21, 2026, 12:31 AM EDT
Withdrawn No phase listed Observational

Diagnosing Malfunctioning Hydrocephalic Shunt Valves With a Flow Sensor

NCT00652249
View directory record Official record
Conditions
Hydrocephalus
Interventions
Not listed
Lead sponsor
Transonic Systems Inc.
Industry
Eligibility
Up to 20 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 5, 2012 · Synced Oct 21, 2026, 12:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Spinal Cord Stimulation for Restless Legs Syndrome

NCT03539081
View directory record Official record
Conditions
Restless Legs Syndrome, Neuropathic Pain
Interventions
Dual-energy X-ray absorptiometry Scan, Laboratory Measurements, Blood Flow Measurement, Continuous Blood Pressure, Partial pressure of oxygen, Microneurography, Anthropometric Measurements, John Hopkins Restless Legs Severity Scale, Continuous Blood Pressure Diary
Diagnostic Test · Other · Behavioral
Lead sponsor
Marshall Holland
Other
Eligibility
18 Years to 85 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Sep 21, 2023 · Synced Oct 21, 2026, 12:31 AM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

Study of the Effect of Clinical Procedures on Drug Delivery of Mylan Fentanyl Transdermal System 25 µg/hr and Duragesic® 25 µg/hr

NCT00648414
View directory record Official record
Conditions
Healthy
Interventions
Mylan Fentanyl Transdermal System 25 mcg/h + Clinical Procedure 1, Mylan Fentanyl Transdermal System 25 mcg/h + Clinical Procedure 2, Mylan Fentanyl Transdermal System 25 mcg/h + Clinical Procedure 3, Duragesic 25 mcg/h + Clinical Procedure 1, Duragesic 25 mcg/h + Clinical Procedure 2, Duragesic 25 mcg/h + Clinical Procedure 3
Drug
Lead sponsor
Mylan Pharmaceuticals Inc
Industry
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2006
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Apr 23, 2024 · Synced Oct 21, 2026, 12:31 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Ultrasound Perfusion Estimation for Assessment of Peripheral Arterial Disease

NCT06952543
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Ultrasound Imaging
Diagnostic Test
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 21, 2026, 12:31 AM EDT
Recruiting Not applicable Interventional

ELEVATE High-Risk PCI Pivotal Study

NCT07001332
View directory record Official record
Conditions
High-Risk Percutaneous Coronary Intervention (High-risk PCI)
Interventions
Elevate, Impella
Device
Lead sponsor
Magenta Medical Ltd.
Industry
Eligibility
18 Years to 88 Years
Enrollment
290 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
33
States / cities
Phoenix, Arizona • Scottsdale, Arizona • La Jolla, California + 23 more
Source: ClinicalTrials.gov public record
Updated Oct 9, 2026 · Synced Oct 21, 2026, 12:31 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

The Analysis of Skin Temperature by Long Wave Infrared Imaging to Determine Its Effectiveness as a Predictor of Tissue Injury

NCT00664235
View directory record Official record
Conditions
Pressure Ulcers, Tissue Injury
Interventions
Not listed
Lead sponsor
Trillennium Medical Imaging, Inc.
Industry
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 22, 2008 · Synced Oct 21, 2026, 12:31 AM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Splanchnic Venous Capacitance in Postural Tachycardia Syndrome

NCT05375968
View directory record Official record
Conditions
Postural Tachycardia Syndrome (POTS)
Interventions
Measurement of Splanchnic venous capacitance(SVC)done at Baseline and after 90 min of 75 g glucose in Healthy Controls POTS patients, Measurement of Splanchnic venous capacitance(SVC)done at Baseline and after 90 min of 75 g glucose in Healthy Controls, Compare change is SVC and SMA flow due to GIP antagonist GIP(3-30)NH2, Compare change is SVC and SMA flow due to saline
Diagnostic Test · Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 50 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 5, 2025 · Synced Oct 21, 2026, 12:31 AM EDT
Completed Not applicable Interventional Results available

Endurant Stent Graft System Post Approval Study (ENGAGE PAS)

NCT01379222
View directory record Official record
Conditions
Aortic Aneurysm, Abdominal
Interventions
Endurant Stent Graft System
Device
Lead sponsor
Medtronic Cardiovascular
Industry
Eligibility
18 Years and older
Enrollment
178 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
24
States / cities
Los Angeles, California • Stanford, California • New Haven, Connecticut + 20 more
Source: ClinicalTrials.gov public record
Updated Oct 29, 2021 · Synced Oct 21, 2026, 12:31 AM EDT
Active, not recruiting No phase listed Observational

Eye Pressure Lowering Surgery

NCT01931904
View directory record Official record
Conditions
Glaucoma
Interventions
Not listed
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 85 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2031
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 21, 2026, 12:31 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Advanced MRI for Uteroplacental Flow, Perfusion, Oxygenation & Inflammation

NCT02791568
View directory record Official record
Conditions
Pregnancy, Obesity, Preeclampsia
Interventions
Ultrasound Scan, MRI Scan, Ferumoxytol
Procedure · Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
121 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
2
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 22, 2025 · Synced Oct 21, 2026, 12:31 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Pilot Study of Acute Stroke Using the Brainpulse™

NCT03235271
View directory record Official record
Conditions
Stroke, Acute
Interventions
BrainPulse Device
Device
Lead sponsor
Jan Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
252 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2024
U.S. locations
3
States / cities
Arlington Heights, Illinois • Evanston, Illinois • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 7, 2025 · Synced Oct 21, 2026, 12:31 AM EDT
Completed Not applicable Interventional

Ischemic Conditioning Chronic Stroke Study

NCT04039399
View directory record Official record
Conditions
Stroke
Interventions
Ischemic Conditioning, Sham Ischemic Conditioning
Procedure
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 85 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 25, 2023 · Synced Oct 21, 2026, 12:31 AM EDT
Completed No phase listed Observational

Respiratory Supports and COVID-19 Mortality

NCT04832061
View directory record Official record
Conditions
COVID-19
Interventions
Respiratory supports
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
2,300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 13, 2021 · Synced Oct 21, 2026, 12:31 AM EDT