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ClinicalTrials.gov public records Last synced Nov 4, 2026, 12:54 AM EST

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Showing 121–144 of 234 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Primary Motor Cortex Stimulation Clear all

Conditions: Major Depressive Disorder, Recurrent, Mild, Depressive Disorder, Major
Interventions: Transcranial Magnetic Stimulation (TMS), Magnetic Resonance Spectroscopy and Imaging; Device
Lead sponsor: Mayo Clinic; Other
Eligibility: 13 Years to 21 Years
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2019
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Scrotal Pain
Interventions: Transcranial magnetic stimulation; Other
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years and older · Male only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Cognitive Dysfunction
Interventions: Transcranial Magnetic Stimulation (TMS); Device
Lead sponsor: University of Arizona; Other
Eligibility: 60 Years to 75 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Tucson, Arizona

Conditions: Stroke
Interventions: Paired-Associative Stimulation (PAS), Vagus Nerve Stimulation (VNS), Sham Stimulation; Other
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 75 Years
Enrollment: 26 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Anterior Cruciate Ligament Reconstruction Rehabilitation, Quadriceps Muscle Function
Interventions: active transcranial direct current stimulation (tDCS), sham transcranial direct current stimulation (tDCS); Device
Lead sponsor: Arcadia University; Other
Eligibility: 18 Years to 35 Years · Female only
Enrollment: 42 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Glenside, Pennsylvania

Conditions: Cortical Activation
Interventions: transcranial magnetic stimulation; Device
Lead sponsor: University of Pennsylvania; Other
Eligibility: 20 Years to 40 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Pain, Pregnancy
Interventions: painDETECT Questionnaire, Pain Catastrophizing Scale, Pain Intensity Scale, Pain Interference Scale, Pain Behavior Scale, Beck Depression Inventory, Visual Analogue Scale, Patient's Global Impression of Change Scale & Clinical Global Impression-Global Improvement Scale, Transcranial Magnetic Stimulation; Behavioral · Device
Lead sponsor: University of Arkansas; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Little Rock, Arkansas

Conditions: Transcranial Magnetic Stimulation
Interventions: transcranial magnetic stimulation; Device
Lead sponsor: Florida State University; Other
Eligibility: 18 Years to 30 Years
Enrollment: 53 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 2
States / cities: Tallahassee, Florida

Conditions: Post-Operative Pain
Interventions: tDCS; Device
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 75 Years
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Alzheimer Disease and Related Dementias, Cognition, Mobility Disability
Interventions: Personalized Transcranial Direct Current Stimulation (tDCS), Active-Sham; Other
Lead sponsor: Hebrew SeniorLife; Other
Eligibility: 65 Years to 90 Years
Enrollment: 128 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Roslindale, Massachusetts

Conditions: Chemotherapy-induced Peripheral Neuropathy
Interventions: transcranial direct current stimulation Soterix REMOTE 1x1 miniCT; Device
Lead sponsor: Morgan State University; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2029
U.S. locations: 2
States / cities: Baltimore, Maryland

Conditions: Pain, Burn Injury
Interventions: Transcranial Direct Current Stimulation (tDCS); Device
Lead sponsor: Spaulding Rehabilitation Hospital; Other
Eligibility: 18 Years to 64 Years
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Parkinson Disease
Interventions: Neopulse Magnetic Stimulator; Device
Lead sponsor: National Institute of Neurological Disorders and Stroke (NINDS); NIH
Eligibility: Not listed
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2005
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Essential Tremor
Interventions: Activa PC+S; Device
Lead sponsor: University of Washington; Other
Eligibility: 18 Years to 80 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2022
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Drug Abuse, Nicotine Dependence
Interventions: MagPro X100 Magnetic Stimulator, Transcranial Rotating Magnetic Stimulator, Magnetom Prisma Fit 3T Scanner; Device
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 80 Years
Enrollment: 1,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2029
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Movement Disorder, Healthy
Interventions: Not listed
Lead sponsor: National Institute of Neurological Disorders and Stroke (NINDS); NIH
Eligibility: Not listed
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2001 – 2002
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Healthy
Interventions: Not listed
Lead sponsor: National Institute of Neurological Disorders and Stroke (NINDS); NIH
Eligibility: 18 Years to 60 Years
Enrollment: 168 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2014
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Stroke, Upper Extremity Paresis, Hemiplegia
Interventions: Active conventional tDCS montage plus CCFES, Active unconventional tDCS montage plus CCFES, Sham tDCS plus CCFES, CCFES with Occupational Therapy; Device · Behavioral
Lead sponsor: MetroHealth Medical Center; Other
Eligibility: 21 Years to 90 Years
Enrollment: 63 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Motor Activity
Interventions: tDCS; Device
Lead sponsor: Indiana University; Other
Eligibility: 18 Years to 45 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Tic Disorder
Interventions: cTBS (accelerated continuous theta burst stimulation); Device
Lead sponsor: University of California, San Francisco; Other
Eligibility: 15 Years to 35 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Blepharospasm, Focal Dystonia
Interventions: repetitive transcranial magnetic stimulation (rTMS); Procedure
Lead sponsor: National Institute of Neurological Disorders and Stroke (NINDS); NIH
Eligibility: 18 Years and older
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Stroke
Interventions: Single-pulse Transcranial Magnetic Stimulation (TMS), Paired-pulse Transcranial Magnetic Stimulation (ppTMS), Low-frequency Repetitive Transcranial Magnetic Stimulation (rTMS), Sham Motor Cortex Stimulation; Device
Lead sponsor: Emory University; Other
Eligibility: 40 Years to 80 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2021
U.S. locations: 3
States / cities: Atlanta, Georgia

Conditions: Parkinson's Disease, Depression
Interventions: Repetitive transcranial magnetic stimulation (rTMS); Device
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 21 Years to 85 Years
Enrollment: 61 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 5
States / cities: Los Angeles, California • Gainesville, Florida • Boston, Massachusetts + 2 more

Conditions: Stroke
Interventions: Not listed
Lead sponsor: National Institute of Neurological Disorders and Stroke (NINDS); NIH
Eligibility: 18 Years to 90 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2010
U.S. locations: 1
States / cities: Bethesda, Maryland

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Cortical Excitability and Inhibition in MDD

Transcranial Magnetic Stimulation for Chronic Scrotal Content Pain

Probing Cortical Excitability and Cognitive Function With TMS

VNS-induced Corticospinal Plasticity

Determining the Effects of Non-invasive Brain Stimulation to Improve Quadriceps Muscle Function After ACL Reconstruction

Menstrual Cycle TMS Plasticity Pilot

Neuropathic Pain in Pregnancy

cTBS/fMRI Study of Hierarchical Control in the PFC

Evaluation of the Effectiveness of tDCS in the Management of Perioperative Pain

Home-Based Brain Stimulation for Motoric Cognitive Risk Syndrome

Neural and Immune Correlates of CIPN and Possible Analgesic Effect of Non-invasive Motor Cortex Stimulation

Effects of Transcranial Direct Current Stimulation (tDCS) on Neuropathic Symptoms Due to Burn Injury

Study of Repetitive Transcranial Magnetic Stimulation in Parkinson's Disease

Demand-driven Management of Essential Tremor

Advanced Functional and Structural MRI Techniques for Neuropharmacological Imaging

Brain Excitability During Self-Paced Voluntary Movements

Detecting a Reward Signal in the Motor Cortex

tDCS + CCFES-mediated Functional Task Practice for Post-stroke Upper Extremity Hemiplegia

Modulation of Motor Learning Via tDCS in a Dexterous Video Game Task

Teen and Adult Tic TMS Study

Brain Stimulation to Treat Blepharospasm or Meige Syndrome

Customized Cortical Stimulation Therapy in the Rehabilitation of Stroke Patients

rTMS for Motor and Mood Symptoms of Parkinson's Disease

Influence of Theta Burst Stimulation and Carbidopa-Levodopa on Motor Performance in Stroke Patients