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Showing 25–48 of 98 matching trials from the live ClinicalTrials.gov search.
Conditions
Hypertension, Gut Dysbiosis, Overweight , Obesity
Interventions
Synbiotic, Placebo
Dietary Supplement
Lead sponsor
Southern Utah University
Other
Eligibility
18 Years to 60 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Cedar, Utah
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Infant Microbiota and Probiotic Intake Study

NCT02457338
Conditions
Healthy
Interventions
Bifidobacterium
Dietary Supplement
Lead sponsor
University of California, Davis
Other
Eligibility
21 Years to 45 Years · Female only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2027
U.S. locations
1
States / cities
Sacramento, California
Conditions
Bile Acid Malabsorption, Bile Acid Diarrhea
Interventions
De Simone formulation probiotic, Placebo
Dietary Supplement
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Appendicitis, Appendicitis; Perforation
Interventions
Lactobacillus rhamnosus GG (LGG) Probiotic, Placebo
Dietary Supplement
Lead sponsor
Children's Health
Other
Eligibility
4 Years to 18 Years
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Dallas, Texas
Conditions
Digestive Health
Interventions
30 day wellness program
Other
Lead sponsor
Peryam & Kroll Research Corporation
Other
Eligibility
20 Years to 65 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Chattanooga, Tennessee
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Probiotics for Anxiety Study

NCT06466603
Conditions
Anxiety
Interventions
GABA Probiotic Dose 1, GABA Probiotic Dose 2, Placebo Group
Dietary Supplement
Lead sponsor
Verb Biotics LLC
Industry
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Fatty Liver Disease, Fibrosis, Liver, Cirrhosis, Liver, Steatohepatitis, Nonalcoholic
Interventions
Align Probiotic Supplement Capsule, Placebos
Drug
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Farmington Hills, Michigan
Conditions
Fecal Analysis
Interventions
ProNutrients Probiotic
Dietary Supplement
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 70 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Health, Subjective, Gastrointestinal Dysfunction, Cardiovascular Risk Factor, Autoimmune Diseases, Dental Diseases, Hormone Disturbance, Neurocognitive Dysfunction
Interventions
Supplements and/or medical foods, Behavioral change support program, Food plan
Dietary Supplement · Behavioral · Other
Lead sponsor
Metagenics, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Gig Harbor, Washington
Conditions
Bacterial Vaginosis, Yeast Infection
Interventions
Prebiotic + Probiotic Supplement, Active Placebo Supplement, Excipient Placebo Supplement
Dietary Supplement
Lead sponsor
Happy V
Industry
Eligibility
25 Years and older · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Santa Monica, California
Completed Not applicable Interventional Accepts healthy volunteers

Impact of B. Adolescentis iVS-1 Probiotic on Gastrointestinal Outcomes

NCT07408518
Conditions
Digestive Disease, Gut Health
Interventions
Probiotic, Placebo
Dietary Supplement · Other
Lead sponsor
Synbiotic Health
Industry
Eligibility
18 Years to 75 Years
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Alzheimer Disease
Interventions
Lifestyle medicine
Behavioral
Lead sponsor
Preventive Medicine Research Institute
Other
Eligibility
45 Years to 90 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
4
States / cities
San Diego, California • Sausalito, California • Boston, Massachusetts + 1 more
Conditions
Feeding Tolerance
Interventions
Probiotic Supplemented Group, Control Group
Dietary Supplement
Lead sponsor
Mercy Health System
Network
Eligibility
Up to 14 Days
Enrollment
133 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
Rockford, Illinois
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The Effect of a Multi-strain Probiotic on Acclimatization to High Altitude

NCT06552806
Conditions
Probiotics
Interventions
SLAB51
Dietary Supplement
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 65 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
2
States / cities
Bishop, California • La Jolla, California
Completed Not applicable Interventional Accepts healthy volunteers

Cognitive and Biological Responses in Stress

NCT05026333
Conditions
Stress, Psychological, Anxiety
Interventions
Cognitive Stress Testing
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Gastrointestinal Symptoms, Digestive Health, Gut Health
Interventions
PhytoPower 1 and PhytoPower 2
Dietary Supplement
Lead sponsor
SF Research Institute, Inc.
Network
Eligibility
18 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
San Francisco, California
Conditions
Type 1 Diabetes (T1D)
Interventions
L. johnsonii Probiotic, Placebo Capsule
Drug
Lead sponsor
University of Florida
Other
Eligibility
8 Years to 18 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Gainesville, Florida
Completed Not applicable Interventional Accepts healthy volunteers

Next-Generation Synbiotic in Individuals With Overweight or Obesity

NCT06213480
Conditions
Overweight and Obesity
Interventions
Synbiotic Group, Placebo Group
Dietary Supplement · Other
Lead sponsor
Texas Christian University
Other
Eligibility
18 Years to 50 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Fort Worth, Texas
Completed Phase 1Phase 2 Interventional Results available

Early FMT for C.Difficile

NCT02465463
Conditions
Clostridium Difficile
Interventions
Fecal microbiota transplant (FMT), flexible sigmoidoscopy
Procedure · Device
Lead sponsor
Emory University
Other
Eligibility
18 Years to 79 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Atlanta, Georgia
Not listed Not applicable Interventional Accepts healthy volunteers

Methylation Diet and Lifestyle Study

NCT03472820
Conditions
Lifestyle, Diet, Healthy
Interventions
Diet Recommendations, Lifestyle Recommendations, Exercise Recommendations, Stress Management Recommendations, PhytoGanix (tropical fruit flavor), UltraFlora Intensive Care
Other
Lead sponsor
National University of Natural Medicine
Other
Eligibility
50 Years to 72 Years · Male only
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
Portland, Oregon
Conditions
Exercise Endurance
Interventions
Probiotic, Placebo
Dietary Supplement
Lead sponsor
Lallemand Health Solutions
Industry
Eligibility
18 Years to 45 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Gainesville, Florida
Recruiting Not applicable Interventional Accepts healthy volunteers

Synbiotic to Attenuate Resorption of the Skeleton

NCT06389539
Conditions
Osteoporosis, Inflammation, Aging
Interventions
SBD111 medical food, Placebo
Other
Lead sponsor
Hebrew SeniorLife
Other
Eligibility
60 Years and older · Female only
Enrollment
220 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
Roslindale, Massachusetts
Conditions
Healthy
Interventions
Omeprazole, Lactobacillus rhamnosus GG, Placebo
Drug · Dietary Supplement
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Scottsdale, Arizona
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Gut Microbiome Response to Long-Haul Travel in Elite Football Players

NCT07585474
Conditions
Microbial Composition, Immune Function
Interventions
Probiotic Capsule, Placebo
Drug
Lead sponsor
Sheffield Hallam University
Other
Eligibility
18 Years to 40 Years · Male only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee