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ClinicalTrials.gov public records Last synced Oct 18, 2026, 6:05 PM EDT

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Showing 289–312 of 735 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Problem Solving Therapy Clear all
Completed Not applicable Interventional Results available

Ending Self Stigma for PTSD

NCT02734212
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Ending Self Stigma for PTSD, Enhanced Treatment as Usual
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 25, 2017 · Synced Oct 18, 2026, 6:05 PM EDT
Withdrawn Not applicable Interventional

Addressing Sleep in Adolescents Post-Concussion ("ASAP Study")

NCT05736692
View directory record Official record
Conditions
Concussion, Brain, Sleep Disorder
Interventions
Brief Sleep Intervention
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
13 Years to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 9, 2024 · Synced Oct 18, 2026, 6:05 PM EDT
Active, not recruiting Not applicable Interventional

The Development of an Integrated Physical Activity and Mental Health Intervention for Veterans With COPD, Emotion Distress, and Low Physical Activity

NCT04953806
View directory record Official record
Conditions
COPD, Depression, Anxiety
Interventions
Step-CBT
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
40 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Oct 18, 2026, 6:05 PM EDT
Completed Not applicable Interventional Results available

Modifiers and Mechanisms of Loneliness Interventions

NCT05812989
View directory record Official record
Conditions
Loneliness
Interventions
Social Engage Coaching, Connect for Caregivers
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
50 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Oct 18, 2026, 6:05 PM EDT
Completed Not applicable Interventional

Preventing Premature Death in Patients With Serious Opioid-related Infection

NCT03999450
View directory record Official record
Conditions
Opioid Use
Interventions
brief motivational intervention (BMI), cognitive behavioral therapy
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jul 28, 2020 · Synced Oct 18, 2026, 6:05 PM EDT
Completed Not applicable Interventional

Comparing Behavior Therapy and Yoga for Treating Depression Among Adults

NCT05546697
View directory record Official record
Conditions
Depression
Interventions
Online- Yoga-based Intervetion, Online- BA
Other · Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
520 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Oct 18, 2026, 6:05 PM EDT
Completed Not applicable Interventional Results available

Hospice Problem Solving Intervention

NCT01444027
View directory record Official record
Conditions
Hospice Informal Caregivers
Interventions
Problem Solving Therapy
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
514 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 13, 2017 · Synced Oct 18, 2026, 6:05 PM EDT
Completed Not applicable Interventional

PACIFIC-FIT: Providing Adults Collaborative Interventions for Ideal Changes Focused Intervention and Tracking

NCT03914508
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Memory + Behavioral Weight Loss
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 65 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Dec 5, 2023 · Synced Oct 18, 2026, 6:05 PM EDT
Completed Not applicable Interventional Results available

Group Based Exposure Therapy for Combat-Related PTSD

NCT00535223
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Group Based Exposure Therapy, Present Centered Group Therapy
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
Male only
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 26, 2015 · Synced Oct 18, 2026, 6:05 PM EDT
Completed Not applicable Interventional

CONcussion Treatment After Combat Trauma (CONTACT)

NCT01387490
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Individualized Scheduled Telephone Support (ISTS), Usual Care (UC)
Behavioral · Other
Lead sponsor
INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium
Other
Eligibility
18 Years and older
Enrollment
366 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
4
States / cities
Durham, North Carolina • Fort Bragg, North Carolina • Fort Lewis, Washington + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 4, 2016 · Synced Oct 18, 2026, 6:05 PM EDT
Completed Not applicable Interventional

PACIFIC: Providing Adults Collaborative Interventions For Ideal Changes

NCT02516839
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Regulation of Cues (ROC), Behavioral Weight Loss (BWL), BWL + ROC, Nutrition Education, Stress Management and Social Support
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 65 Years
Enrollment
271 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Mar 25, 2020 · Synced Oct 18, 2026, 6:05 PM EDT
Completed Phase 4 Interventional Results available

Combination Nicotine Replacement for Alcoholic Smokers

NCT00064844
View directory record Official record
Conditions
Smoking, Alcoholism
Interventions
Cognitive Behavior Therapy for alcohol and smoking cessation, Nicoderm CQ nicotine patch, Placebo gum, Nicotine gum - Nicorette®
Behavioral · Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2006
U.S. locations
1
States / cities
Newington, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 13, 2021 · Synced Oct 18, 2026, 6:05 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Reducing Psychological Barriers to PrEP Persistence Among Pregnant and Postpartum Women in Cape Town, South Africa

NCT05624931
View directory record Official record
Conditions
Depression, Posttraumatic Stress Disorder, Pregnancy Related, Medication Adherence
Interventions
Brief CBT-Based Intervention, Enhanced Treatment as Usual
Behavioral · Other
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
15 Years and older · Female only
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Oct 18, 2026, 6:05 PM EDT
Completed Not applicable Interventional Results available

Community Active and Healthy Families

NCT04414553
View directory record Official record
Conditions
Obesity, Childhood
Interventions
Community Active and Healthy Families
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
5 Years to 99 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
2
States / cities
Aurora, Colorado • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 3, 2025 · Synced Oct 18, 2026, 6:05 PM EDT
Completed Not applicable Interventional

Self-guided Depression Treatment on Long-duration Spaceflights: A Continuation Study

NCT00906581
View directory record Official record
Conditions
Depression
Interventions
Computer-based Problem-Solving Treatment
Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
30 Years to 60 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 13, 2017 · Synced Oct 18, 2026, 6:05 PM EDT
Completed Phase 4 Interventional Results available

Treatment of Severe Childhood Aggression (The TOSCA Study)

NCT00796302
View directory record Official record
Conditions
Attention Deficit Disorder With Hyperactivity
Interventions
Methylphenidate HCl, Risperidone, Parent Management Training (PMT), Placebo
Drug · Behavioral
Lead sponsor
Michael Aman
Other
Eligibility
6 Years to 12 Years
Enrollment
168 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
4
States / cities
Stony Brook, New York • Cleveland, Ohio • Columbus, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 26, 2017 · Synced Oct 18, 2026, 6:05 PM EDT
Completed Not applicable Interventional Results available

Parent-Led Cognitive-Behavioral Teletherapy for Anxiety in Youth With ASD

NCT04111874
View directory record Official record
Conditions
Cognitive Behavioral Therapy, Autism Spectrum Disorder, Anxiety Disorders, Obsessive-Compulsive Disorder, Social Anxiety Disorder, Generalized Anxiety Disorder, Specific Phobia
Interventions
Cognitive Behavioral Teletherapy LTA, Cognitive Behavioral Teletherapy STA
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
7 Years to 13 Years
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 15, 2025 · Synced Oct 18, 2026, 6:05 PM EDT
Completed Not applicable Interventional

Computerized Cognitive Behavioral Therapy Assisted Life Management for Pain in Sickle Cell Disease

NCT03029468
View directory record Official record
Conditions
Sickle Cell Disease, Chronic Pain
Interventions
cognitive behavioral therapy, eEducation
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 8, 2020 · Synced Oct 18, 2026, 6:05 PM EDT
Recruiting Phase 4 Interventional

Varenicline for Smoking Reduction in Veterans Not Ready To Quit

NCT06966362
View directory record Official record
Conditions
Veterans, Tobacco Use Disorder, Cigarette Smoking, Tobacco Dependence
Interventions
Motivation-Phase Varenicline, Motivation-Phase Nicotine Mini-Lozenge, Cessation-Phase Combination Nicotine Replacement Therapy (NRT), Cessation-Phase Varenicline, Motivation-Phase Counseling, Cessation-Phase Counseling
Drug · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
4
States / cities
San Diego, California • Minneapolis, Minnesota • Durham, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Oct 18, 2026, 6:05 PM EDT
Completed Phase 2 Interventional

Culturally Informed Family Based Treatment of Adolescents: A Randomized Trial

NCT01823250
View directory record Official record
Conditions
Substance Use Disorders, Risk Behavior, Psychiatric Disorders, Family Dysfunction
Interventions
Family Therapy based on Structural Family Therapy, Group Therapy, Psychoeducational Sessions, Individual Adolescent Therapy Sessions
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
14 Years to 17 Years
Enrollment
190 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Dec 16, 2015 · Synced Oct 18, 2026, 6:05 PM EDT
Completed Not applicable Interventional Results available

Prospective Case Series to Refine Standalone Cognitive Behavioral Therapy Components for Multiple Sclerosis Fatigue

NCT05848323
View directory record Official record
Conditions
Multiple Sclerosis, Fatigue
Interventions
4-week Relaxation Training, 4-week Behavioral Activation, 4-week Cognitive Therapy
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Nov 26, 2025 · Synced Oct 18, 2026, 6:05 PM EDT
Not listed Phase 1 Interventional

A Treatment Engagement Protocol for Psychiatrically Hospitalized Adolescents at Clinical High Risk for Psychosis

NCT04314635
View directory record Official record
Conditions
Psychosis Nos/Other
Interventions
Brief family engagement intervention for CHR, Treatment as usual (TAU)
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
13 Years to 18 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
East Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 6, 2022 · Synced Oct 18, 2026, 6:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Utilizing A Single Session Problem-Solving Intervention With Caregivers of Pediatric Patients Receiving Chronic Transfusion to Treat Sickle Cell Disease

NCT04606160
View directory record Official record
Conditions
Sickle Cell Disease
Interventions
Single Session Problem-Solving Intervention
Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
7 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 21, 2022 · Synced Oct 18, 2026, 6:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Web-based Programs to Improve and Strengthen Romantic Relationships

NCT02806635
View directory record Official record
Conditions
Romantic Relationship
Interventions
OurRelationship, PREP Online
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 64 Years
Enrollment
1,484 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated Jan 8, 2019 · Synced Oct 18, 2026, 6:05 PM EDT