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ClinicalTrials.gov public records Last synced Oct 21, 2026, 5:22 PM EDT

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Showing 97–120 of 255 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Problem-Solving Individual Therapy Clear all
Completed Not applicable Interventional Accepts healthy volunteers

A Comparison of Two Approaches to Developing Brain Health Programs

NCT04822129
View directory record Official record
Conditions
Older Persons Interested in Improving Their Brain Health
Interventions
Treatment as Usual, Cogtrastim Model
Behavioral
Lead sponsor
Nova Southeastern University
Other
Eligibility
50 Years and older
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Fort Lauderdale, Florida
Source: ClinicalTrials.gov public record
Updated Jul 11, 2023 · Synced Oct 21, 2026, 5:22 PM EDT
Recruiting Not applicable Interventional

Rehabilitation Strategies for Social Participation in Chronic Stroke Survivors

NCT06758505
View directory record Official record
Conditions
Stroke, Chronic Phase of Disease
Interventions
Strategy Training Only, Strategy Training embedded with Acceptance and Commitment Therapy Principles
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 21, 2026, 5:22 PM EDT
Active, not recruiting Not applicable Interventional

HOme-Based Self-management and COgnitive Training CHanges Lives (HOBSCOTCH) -Post-Traumatic Epilepsy (PTE)

NCT05235061
View directory record Official record
Conditions
Epilepsy, Traumatic, Brain Injuries, Traumatic
Interventions
Home Based Self-management and Cognitive Training Changes lives in post traumatic epilepsy (HOBSCOTCH-PTE), HOBSCOTCH-PTE for Caregivers
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Oct 21, 2026, 5:22 PM EDT
Completed Not applicable Interventional Results available

Listening Visits for Emotionally Distressed Mothers of Hospitalized Newborns

NCT03704948
View directory record Official record
Conditions
Nurse Delivered Counseling, Emotional Distress
Interventions
RCT Treatment -Listening Visits delivered by NICU nurse in person, RCT Control Usual mental health care delivered by NICU social workers, Open trial: Listening Visits delivered by a NICU nurse via zoom
Behavioral
Lead sponsor
University of Iowa
Other
Eligibility
18 Years and older · Female only
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Sep 29, 2023 · Synced Oct 21, 2026, 5:22 PM EDT
Recruiting Phase 2 Interventional

Substance Misuse and Family Violence Treatment Fathers

NCT06650267
View directory record Official record
Conditions
Substance Misuse, Violence, Domestic, Child Abuse
Interventions
Fathers for Change (F4C), Individual Drug Counseling (IDC)
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Male only
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
2
States / cities
New Haven, Connecticut • West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 21, 2026, 5:22 PM EDT
Completed Not applicable Interventional Results available

A Pilot Randomized Trial of Video-based Family Therapy for Depressed Home Visited Mothers

NCT04741776
View directory record Official record
Conditions
Perinatal Depression, Postpartum Depression, Family Conflict
Interventions
Resilience Enhancement Skills Training, Problem-Solving Individual Therapy
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
15 Years and older
Enrollment
166 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Jan 8, 2025 · Synced Oct 21, 2026, 5:22 PM EDT
Completed Not applicable Interventional

Effectiveness of Case Management Versus Case Management Plus Problem-solving Therapy to Treat Depression in Low-income Elders

NCT00540865
View directory record Official record
Conditions
Depression
Interventions
Problem-solving therapy (PST), Case management (CM)
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
60 Years to 95 Years
Enrollment
187 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
2
States / cities
San Francisco, California • White Plains, New York
Source: ClinicalTrials.gov public record
Updated Dec 10, 2014 · Synced Oct 21, 2026, 5:22 PM EDT
Completed Not applicable Interventional

Assertive Community Treatment With CBT and SST for Schizophrenia

NCT02254733
View directory record Official record
Conditions
Schizophrenia
Interventions
Cognitive Behavioral Social Skills Training (CBSST), Assertive Community Treatment (ACT)
Behavioral · Other
Lead sponsor
Veterans Medical Research Foundation
Other
Eligibility
18 Years and older
Enrollment
178 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 17, 2016 · Synced Oct 21, 2026, 5:22 PM EDT
Completed Not applicable Interventional

Living Well With Stroke

NCT01133106
View directory record Official record
Conditions
Cerebrovascular Stroke, Depression
Interventions
Brief pleasurable events/behavioral therapy, Standard care
Behavioral · Other
Lead sponsor
University of Washington
Other
Eligibility
21 Years to 100 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 23, 2016 · Synced Oct 21, 2026, 5:22 PM EDT
Not listed Phase 1Phase 2 Interventional

Behavioral Activation With Depressed Adolescents

NCT01137149
View directory record Official record
Conditions
Depression
Interventions
Behavioral Activation Therapy, Treatment as Usual- Psychotherapy
Behavioral
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
11 Years to 18 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 4, 2010 · Synced Oct 21, 2026, 5:22 PM EDT
Recruiting Not applicable Interventional

Cognitive Rehabilitation Following Breast Cancer Treatment

NCT06545045
View directory record Official record
Conditions
Breast Cancer Female
Interventions
Metacognitive Strategy Training (MCST), Inactive Control Group
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
20 Years to 75 Years · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Oct 21, 2026, 5:22 PM EDT
Enrolling by invitation Not applicable Interventional

A Randomized Controlled Trial of ACT-P Versus T4C for Community Reentry

NCT05109689
View directory record Official record
Conditions
Criminal Behavior, Violence
Interventions
ACT-P, T4C
Behavioral
Lead sponsor
Iowa State University
Other
Eligibility
18 Years and older · Male only
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Fort Dodge, Iowa
Source: ClinicalTrials.gov public record
Updated Dec 30, 2024 · Synced Oct 21, 2026, 5:22 PM EDT
Enrolling by invitation Not applicable Interventional

Comparing Two Moral Injury Treatments

NCT07710521
View directory record Official record
Conditions
Moral Injury
Interventions
Acceptance and Commitment Therapy for Moral Injury (ACT-MI), Present Centered Therapy for Moral Injury (PCT-MI)
Behavioral
Lead sponsor
VA Eastern Colorado Health Care System
Federal
Eligibility
18 Years to 89 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 21, 2026, 5:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Problem Solving Intervention for Hospice Caregivers

NCT03712410
View directory record Official record
Conditions
Anxiety Generalized, Quality of Life, Depression
Interventions
PISCES
Behavioral
Lead sponsor
George Demiris, PhD
Other
Eligibility
18 Years and older
Enrollment
523 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 16, 2023 · Synced Oct 21, 2026, 5:22 PM EDT
Completed Not applicable Interventional Results available

Problem Adaptation Therapy (PATH) vs. Supportive Therapy in Treating Depressed, Cognitively Impaired Older Adults

NCT00368940
View directory record Official record
Conditions
Depression
Interventions
PATH, ST-CI
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
65 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
1
States / cities
White Plains, New York
Source: ClinicalTrials.gov public record
Updated Jul 24, 2017 · Synced Oct 21, 2026, 5:22 PM EDT
Recruiting Not applicable Interventional

Leveraging Interventions for Caregiver Growth, Health, Training, Empowerment and Navigation: Comparing Group Behavioral Interventions to Improve Dementia Caregiver Strain

NCT07868588
View directory record Official record
Conditions
Elevated Caregiver Strain, Dementia Caregiver, Caregiver Stress
Interventions
Caring Together, Savvy Caregiver
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Oct 21, 2026, 5:22 PM EDT
Not yet recruiting Not applicable Interventional

VOCALE LBD: Online Peer Support for Caregivers of People With Lewy Body Dementia

NCT07637097
View directory record Official record
Conditions
Lewy Bodies Disease, Depression Disorder, Caregiver Burden, Caregivers
Interventions
VOCALE LBD: Virtual Online Communities for Aging Life Experiences: Lewy Body Dementia, Standard of Care Educational Materials
Behavioral · Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 21, 2026, 5:22 PM EDT
Completed Not applicable Interventional

Dyad Plus Effectiveness/Feasibility

NCT04036331
View directory record Official record
Conditions
Weight Loss, Pediatric Obesity, Overweight Adolescents, Parent-Child Relations, Family and Household
Interventions
Brenner FIT Standard, By Design Essentials, Dyad Plus
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
13 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 21, 2026, 5:22 PM EDT
Recruiting Not applicable Interventional

A Study of a One-Time Counseling Session to Help Reduce Depression, Anxiety, and Distress in People With Cancer

NCT07218250
View directory record Official record
Conditions
Breast Cancer
Interventions
Single Counseling Session, American Cancer Society booklet
Behavioral · Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 21, 2026, 5:22 PM EDT
Completed Not applicable Interventional Results available

Telephone-Based Intervention to Treat Depression and Anxiety in Hispanic Cancer Survivors

NCT04430335
View directory record Official record
Conditions
Survivorship, Cancer, Depression, Anxiety
Interventions
Telephone interview, Cognitive Behavioral Therapy
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 16, 2023 · Synced Oct 21, 2026, 5:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Northern-Manhattan Hispanic Caregiver Intervention Effectiveness Study

NCT02092987
View directory record Official record
Conditions
Depressive Symptoms, Burden
Interventions
Social work support, Educational material, NYU caregiver counseling intervention, REACH OUT counseling intervention
Other · Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 90 Years
Enrollment
221 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 9, 2021 · Synced Oct 21, 2026, 5:22 PM EDT
Completed Phase 2 Interventional

Mind and Body Approaches to Pain Reduction in Youth With Migraine

NCT03472092
View directory record Official record
Conditions
Headache, Migraine, Migraine, Migraine Disorders, Headache
Interventions
Cognitive Behavioral Therapy (CBT), Placebo, Amitriptyline, Biofeedback-Assisted Relaxation Training (BART), Cognitive Reappraisal Training (CR)
Behavioral · Drug
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
10 Years to 17 Years
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 26, 2025 · Synced Oct 21, 2026, 5:22 PM EDT
Completed Not applicable Interventional

Cognitive Enhancement Therapy for Adult Autism Spectrum Disorder

NCT00902798
View directory record Official record
Conditions
Autistic Disorder, Autism Spectrum Disorder, Asperger's Syndrome, Pervasive Developmental Disorder
Interventions
Cognitive Enhancement Therapy, Enriched Supportive Therapy
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
16 Years to 45 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 13, 2020 · Synced Oct 21, 2026, 5:22 PM EDT
Recruiting Not applicable Interventional

A Primary Care-Based Psychosocial Intervention To Improve Cognitive & Depression Outcomes in Older Adults With MCI & Early Stage AD

NCT05081596
View directory record Official record
Conditions
Depression, Pain, Cognitive Impairment
Interventions
PATH-Pain
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
60 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
White Plains, New York
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Oct 21, 2026, 5:22 PM EDT