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ClinicalTrials.gov public records Last synced Oct 23, 2026, 10:14 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 937–960 of 1,179 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Problem-solving Clear all
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Cognitive Rehabilitation and Exposure Therapy for Geriatric Hoarding

NCT05254015
View directory record Official record
Conditions
Hoarding Disorder, Obsessive-Compulsive Disorder
Interventions
Cognitive Rehabilitation and Exposure/Sorting Therapy (CREST), Case Management
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
50 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 6, 2023 · Synced Oct 23, 2026, 10:14 PM EDT
Completed Not applicable Interventional

Insulin Start Therapy Application With Resources and Training

NCT03999268
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
I-START, Standard Insulin Administration Education
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 8, 2022 · Synced Oct 23, 2026, 10:14 PM EDT
Completed Phase 3 Interventional

Preventing Depression in Patients With Macular Degeneration

NCT00042211
View directory record Official record
Conditions
Depression, Macular Degeneration
Interventions
Problem Solving Treatment, Control
Behavioral
Lead sponsor
Thomas Jefferson University
Other
Eligibility
65 Years and older
Enrollment
206 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2006
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 8, 2014 · Synced Oct 23, 2026, 10:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Risk After an Adverse Pregnancy Outcome

NCT01182363
View directory record Official record
Conditions
Maternal Depression
Interventions
Project Solve Education
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
Female only
Enrollment
188 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
4
States / cities
Boston, Massachusetts • Natick, Massachusetts • Quincy, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 28, 2014 · Synced Oct 23, 2026, 10:14 PM EDT
Completed Not applicable Interventional

Effective Management of Emotional Response to Generate Well-Being Post-HF Exacerbation

NCT03043261
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
Williams LifeSkills
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 7, 2018 · Synced Oct 23, 2026, 10:14 PM EDT
Not listed Not applicable Interventional

The REACH Intervention for Caregivers of Veterans and Service Members With TBI

NCT06111794
View directory record Official record
Conditions
Traumatic Brain Injury, Caregiver
Interventions
REACH TBI
Other
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Aug 9, 2024 · Synced Oct 23, 2026, 10:14 PM EDT
Completed Phase 2Phase 3 Interventional

Prolonged Exposure Therapy for Post Traumatic Stress Disorder Following Sexual Assault

NCT00057629
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Prolonged Exposure (PE), Treatment as usual group therapy (TUGT), Supportive counseling (SC)
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 67 Years · Female only
Enrollment
187 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2009
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 13, 2015 · Synced Oct 23, 2026, 10:14 PM EDT
Terminated Not applicable Interventional

Neuroimaging for Depression

NCT00864630
View directory record Official record
Conditions
Depression
Interventions
Computer-based problem solving therapy
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
30 Years to 60 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 24, 2011 · Synced Oct 23, 2026, 10:14 PM EDT
Recruiting Not applicable Interventional

Enhancing Sleep Quality for Nursing Home Residents With Dementia - R33 Phase

NCT05820919
View directory record Official record
Conditions
Alzheimer Disease, Dementia, Sleep Disorder, Sleep Disturbance
Interventions
LOCK Sleep Program, No intervention (control period/baseline data collection)
Behavioral · Other
Lead sponsor
University of Alabama, Tuscaloosa
Other
Eligibility
50 Years and older
Enrollment
456 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
3
States / cities
Lakewood, Colorado • Murfreesboro, Tennessee • San Marcos, Texas
Source: ClinicalTrials.gov public record
Updated Mar 12, 2024 · Synced Oct 23, 2026, 10:14 PM EDT
Completed Not applicable Interventional Results available

Piloting the IPROACTIF Program to Preserve Functioning and Prevent Cognitive Decline

NCT04682977
View directory record Official record
Conditions
Heart Disease (Coronary Artery Disease, Ischemic Heart Disease, Hypertensive Heart Disease), Uncontrolled Diabetes (HBA1c ≥ 10)
Interventions
IPROACTIF (Integrated PRimary Care and Occupational Therapy for Aging and Chronic Disease Treatment to preserve Independence and Functioning), Usual primary care services
Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
55 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 19, 2025 · Synced Oct 23, 2026, 10:14 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Family Telemental Health Intervention for Veterans With Dementia

NCT03116464
View directory record Official record
Conditions
Dementia Family Caregiver Burden and Conflict
Interventions
Telemental Health Family Intervention
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 10, 2025 · Synced Oct 23, 2026, 10:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

RESCUE Stroke Caregiver Website to Enhance Discharge Planning

NCT01600131
View directory record Official record
Conditions
Depression, Quality of Life, Self Efficacy, Recovery of Function, Stress, Positive Aspects of Caregiving
Interventions
Caregiver problem-solving, Standard Care
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
174 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2021
U.S. locations
3
States / cities
Gainesville, Florida • Miami, Florida • Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jan 17, 2023 · Synced Oct 23, 2026, 10:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Coping in Heart Failure Partnership Intervention

NCT05337293
View directory record Official record
Conditions
Heart Failure
Interventions
COPE-HF Partnership Intervention, Attention
Behavioral · Other
Lead sponsor
Florida State University
Other
Eligibility
18 Years and older
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
2
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Mar 21, 2023 · Synced Oct 23, 2026, 10:14 PM EDT
Active, not recruiting Phase 3 Interventional

Optimizing Tobacco Use Treatment for PLWHA

NCT04176172
View directory record Official record
Conditions
HIV/AIDS, Nicotine Dependence
Interventions
Varenicline, Nicotine patch, Standard treatment, Standard treatment + Managed Problem Solving (MAPS) adherence intervention
Drug · Behavioral
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older
Enrollment
340 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
2
States / cities
Chicago, Illinois • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 23, 2026, 10:14 PM EDT
Completed Not applicable Interventional Results available

Titrated Disease Management for Patients With Hypertension

NCT01390272
View directory record Official record
Conditions
Hypertension
Interventions
Booster/ low resource, Medium/Level 1 resource intensity, High/Level 2 resource intensity
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
385 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 11, 2019 · Synced Oct 23, 2026, 10:14 PM EDT
Completed Not applicable Interventional

MANAGE AT WORK: Addressing the Challenge of Chronic Physical Health Conditions in the Workplace

NCT01978392
View directory record Official record
Conditions
Chronic Physical Health Conditions
Interventions
Self-management group workshops
Behavioral
Lead sponsor
Liberty Mutual Research Institute for Safety
Industry
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
4
States / cities
Worcester, Massachusetts • Hanover, New Hampshire • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 2, 2017 · Synced Oct 23, 2026, 10:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

VOCALE LBD+ for Caregivers of Persons With Lewy Body Dementia

NCT05622734
View directory record Official record
Conditions
Caregiver Burden, Lewy Body Disease, Stress, Skill, Coping
Interventions
VOCALE LBD+
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 23, 2026, 10:14 PM EDT
Completed Not applicable Interventional Results available

Engage Psychotherapy to Promote Connectedness in Caregivers

NCT04176601
View directory record Official record
Conditions
Loneliness, Social Isolation, Caregiver Burnout
Interventions
Engage coaching
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
50 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Feb 25, 2025 · Synced Oct 23, 2026, 10:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Addressing Social Determinants of Health & Diabetes Self-Management in Vulnerable Populations

NCT03802825
View directory record Official record
Conditions
Diabetes
Interventions
Diabetes Self-Management Training, Standard Patient Navigation
Behavioral · Other
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 29, 2022 · Synced Oct 23, 2026, 10:14 PM EDT
Not listed Not applicable Interventional

Randomized Controlled Trial Using Patient Reported Outcomes and Care Managers to Improve HIV Medication Adherence in Routine Clinical Care

NCT01505660
View directory record Official record
Conditions
HIV
Interventions
Care management
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 14, 2015 · Synced Oct 23, 2026, 10:14 PM EDT
Completed Phase 3 Interventional

An Intervention to Improve Outcomes in Patients With Advanced Cancer

NCT01272024
View directory record Official record
Conditions
Cancer
Interventions
Symptom Education, Intervention
Behavioral
Lead sponsor
Yale University
Other
Eligibility
21 Years and older
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 15, 2016 · Synced Oct 23, 2026, 10:14 PM EDT
Recruiting Not applicable Interventional

Improving Cognitive Function in Older Adults Undergoing Stem Cell Transplant

NCT04898790
View directory record Official record
Conditions
Leukemia, Lymphoma, Multiple Myeloma, Myelodysplastic Syndromes (MDS), Myeloproliferative Neoplasm
Interventions
CHAMPS-II adapted to adults 60+ years in HCT setting
Behavioral
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 23, 2026, 10:14 PM EDT
Completed Phase 2 Interventional

Prostate Cancer Symptom Management for Low Literacy Men

NCT00983710
View directory record Official record
Conditions
Prostate Cancer
Interventions
PC-PEP - Prostate Cancer Patient Education Program, Usual care
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older · Male only
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 23, 2018 · Synced Oct 23, 2026, 10:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Engaging Self-regulation Targets to Improve Mood and Weight and Understand Mechanism in Depressed and Obese Adults

NCT03841682
View directory record Official record
Conditions
Obesity, Depression
Interventions
I-CARE2
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
2
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 21, 2021 · Synced Oct 23, 2026, 10:14 PM EDT