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Showing 1–15 of 15 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Procyanidins Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Absorption and Metabolism of Dietary Cocoa Procyanidins in Humans

NCT01483508
View directory record Official record
Conditions
Healthy
Interventions
Flavanol- and procyanidins-containing drink, Procyanidins-containing drink, Flavanol-containing drink
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 70 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Oct 24, 2012 · Synced Sep 2, 2026, 6:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Randomized Controlled Cocoa-Appetite Trial

NCT02408289
View directory record Official record
Conditions
Obesity
Interventions
Lo-Flav, Hi-Flav, Epicatechin, Procyanidins
Dietary Supplement
Lead sponsor
Brooklyn College of the City University of New York
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Jan 12, 2016 · Synced Sep 2, 2026, 6:32 AM EDT
Withdrawn Phase 1 Interventional

Study of Metformin Plus Oligomeric Procyanidin Complex for Pharmacologic Manipulation of AGE (Advanced Glycation Endproducts) Levels in Prostate Cancer Patients

NCT03465345
View directory record Official record
Conditions
Prostate Cancer
Interventions
Metformin, Oligomeric Procyanidin Complex
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 2, 2018 · Synced Sep 2, 2026, 6:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

RiteStart Personal Nutritional Dietary Study

NCT05130905
View directory record Official record
Conditions
Healthy Nutrition
Interventions
RiteStart Supplement
Dietary Supplement
Lead sponsor
4Life Research, LLC
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Sandy City, Utah
Source: ClinicalTrials.gov public record
Updated Nov 22, 2021 · Synced Sep 2, 2026, 6:32 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

IH636 Grape Seed Extract in Preventing Breast Cancer in Postmenopausal Women at Risk of Developing Breast Cancer

NCT00100893
View directory record Official record
Conditions
Breast Cancer
Interventions
IH636 grape seed proanthocyanidin extract
Dietary Supplement
Lead sponsor
City of Hope Medical Center
Other
Eligibility
40 Years to 75 Years · Female only
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2013
U.S. locations
1
States / cities
Duarte, California
Source: ClinicalTrials.gov public record
Updated Jun 7, 2015 · Synced Sep 2, 2026, 6:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Absorption, Metabolism and Excretion of Dietary Polyphenolic Bioactives in Humans

NCT03194620
View directory record Official record
Conditions
Healthy
Interventions
Thearubigins, Theaflavins, Procyanidin Dimer B2 (DB2), (-)-Epigallocatechin-3-O-gallate (EGCG), (-)-Epicatechin-3-O-gallate (ECG), (-)-Epicatechin (EC), (-)-Epigallocatechin (EGC), Control
Other
Lead sponsor
University of California, Davis
Other
Eligibility
25 Years to 60 Years · Male only
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Nov 5, 2017 · Synced Sep 2, 2026, 6:32 AM EDT
Completed Not applicable Interventional

Trial of Two Dietary Programs on Cardiometabolic Risk Factors in Subjects With Metabolic Syndrome

NCT01010841
View directory record Official record
Conditions
Metabolic Syndrome, Overweight, Obesity, Hypercholesterolemia
Interventions
UltraMealPlus 360 (Medical food), Low-glycemic-load diet
Dietary Supplement · Other
Lead sponsor
MetaProteomics LLC
Industry
Eligibility
20 Years to 75 Years · Female only
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 11, 2012 · Synced Sep 2, 2026, 6:32 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Evaluation of AppleX™ Apple Extract on Anti-Inflammatory and Healthy Aging Effects

NCT07678346
View directory record Official record
Conditions
Systemic Inflammation (hsCRP), Healthy Aging, Vitality, Healthy Adult Participants
Interventions
Apple Extract, Placebo
Dietary Supplement · Other
Lead sponsor
Nutraland USA, Inc.
Industry
Eligibility
45 Years to 70 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Sep 2, 2026, 6:32 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Effect of OPC Factor on Energy Levels

NCT00318019
View directory record Official record
Conditions
Healthy
Interventions
OPC Factor(TM), Placebo
Dietary Supplement · Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
45 Years to 65 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 16, 2011 · Synced Sep 2, 2026, 6:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Multiple Daily Condensed Tannin Supplementation and Iron Bioavailability: The Tannin Dose Response Trial

NCT03030716
View directory record Official record
Conditions
Iron Deficiency Anemia, Iron-deficiency
Interventions
95% condensed proanthocyanidins from grape seed extract
Dietary Supplement
Lead sponsor
Kansas State University
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Manhattan, Kansas
Source: ClinicalTrials.gov public record
Updated Jan 24, 2017 · Synced Sep 2, 2026, 6:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cranberry Proanthocyanidins for Modification of Intestinal E. Coli Flora and Prevention of Urinary Tract Infections in UTI-Susceptible Women

NCT01219595
View directory record Official record
Conditions
Urinary Tract Infection
Interventions
Sweetened, dried cranberries, Strawberry Fruit Pieces, Observation
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 28, 2016 · Synced Sep 2, 2026, 6:32 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Bioavailability Study of Cinnamon in Healthy Subjects

NCT01847053
View directory record Official record
Conditions
Healthy Males
Interventions
cinnamon, Oatmeal
Other
Lead sponsor
McCormick and Company, Inc.
Industry
Eligibility
18 Years to 40 Years · Male only
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Addison, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 5, 2020 · Synced Sep 2, 2026, 6:32 AM EDT
Completed Not applicable Interventional

UTI Prophylaxis With Cranberry Extract After Female Incontinence Surgery

NCT03898310
View directory record Official record
Conditions
Urinary Tract Infections, Incontinence
Interventions
Cranberry extract capsules, Placebo capsule
Dietary Supplement
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
141 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jun 12, 2023 · Synced Sep 2, 2026, 6:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Absorption, Metabolism, and Excretion of (-)-[2-14C]Epicatechin in Humans

NCT01969994
View directory record Official record
Conditions
ADME
Interventions
Controlled dietary background, (-)-[2-14C]epicatechin intake
Other
Lead sponsor
The Institutes for Pharmaceutical Discovery, LLC
Industry
Eligibility
18 Years to 50 Years · Male only
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 24, 2013 · Synced Sep 2, 2026, 6:32 AM EDT
Terminated Phase 2 Interventional Results available

Leucoselect Phytosome for Neoadjuvant Treatment of Early Stage Lung Cancer

NCT04515004
View directory record Official record
Conditions
Early Stage Lung Cancer (I and II)
Interventions
leucoselect phytosome
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Sep 2, 2026, 6:32 AM EDT