Independent directory Public ClinicalTrials.gov records United States
Clear filters
ClinicalTrials.gov public records Last synced Sep 6, 2026, 8:03 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–14 of 14 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Prostate Carcinoma, Stage I Prostate Cancer AJCC v8, Stage II Prostate Cancer AJCC v8
Interventions
MRI-Guided Transurethral Ultrasound Ablation, Questionnaire Administration, Digital Rectal Examination, Cystoscopy, Biopsy, Bone Scan, PSMA PET Scan, Multiparametric Magnetic Resonance Imaging
Procedure · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
45 Years to 80 Years · Male only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Clinical Feasibility Study to Evaluate the Safety and Performance of the Profound Matrix System

NCT06157567
Conditions
Skin Laxity, Wrinkle, Skin Condition
Interventions
Profound Matrix
Device
Lead sponsor
Candela Corporation
Industry
Eligibility
18 Years to 75 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2028
U.S. locations
4
States / cities
Jacksonville, Florida • Marlborough, Massachusetts • Fayetteville, North Carolina + 1 more
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Radio-Frequency Microneedling Device

NCT06228144
Conditions
Healthy
Interventions
Candela Profound System with Dermal Handpiece, Experimental Dermal Cooling Device
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Boston, Massachusetts
Active, not recruiting Not applicable Interventional

Multichannel Vestibular Implant Early Feasibility Study

NCT02725463
Conditions
Other Disorders of Vestibular Function, Bilateral, Bilateral Vestibular Deficiency (BVD), Gentamicin Ototoxicity, Labyrinth Diseases, Vestibular Diseases, Sensation Disorders
Interventions
Labyrinth Devices MVI™ Multichannel Vestibular Implant
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
22 Years to 90 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Not listed Not applicable Interventional Accepts healthy volunteers

Treatment With the Profound System for Submental Laxity

NCT02595216
Conditions
Submental Laxity
Interventions
Profound System
Device
Lead sponsor
Syneron Medical
Industry
Eligibility
18 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
5
States / cities
San Mateo, California • San Ramon, California • Alpharetta, Georgia + 2 more
Conditions
Hearing Loss
Interventions
HiRes 90K Bionic Ear System
Device
Lead sponsor
Advanced Bionics
Industry
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
9
States / cities
Los Angeles, California • Palo Alto, California • Miami, Florida + 6 more
Conditions
Hearing Loss, Ear Diseases, Hearing Disorders, Otorhinolaryngologic Diseases, Asymmetrical Hearing Loss, Single-Sided Deafness
Interventions
HiResolution Bionic Cochlear Implant
Device
Lead sponsor
Advanced Bionics
Industry
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
2
States / cities
Sarasota, Florida • Seattle, Washington
Completed Not applicable Interventional Accepts healthy volunteers

Functional Usability and Feasibility Testing of the Profound Matrix™ System

NCT06192550
Conditions
Wrinkle, Acne Scars - Mixed Atrophic and Hypertrophic
Interventions
Profound Matrix™ System
Device
Lead sponsor
Candela Corporation
Industry
Eligibility
18 Years to 75 Years
Enrollment
193 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
4
States / cities
Marlborough, Massachusetts • New York, New York • Charlotte, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers Results available

Radio Frequency Microneedling for Suprapatellar Skin

NCT03507036
Conditions
Skin Laxity
Interventions
Profound system
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Dallas, Texas
Not listed Not applicable Interventional Accepts healthy volunteers

Transitioning to a Valve-Gated Intrathecal Drug Delivery System (IDDS)

NCT04530955
Conditions
Injuries, Spinal Cord, CVA (Cerebrovascular Accident), Traumatic Brain Injury, MS (Multiple Sclerosis), Muscle Spasticity, Cerebral Palsy, Spastic
Interventions
Prometra II Programmable Pump - Flowonix Medical
Device
Lead sponsor
Culicchia Neurological Clinic
Other
Eligibility
22 Years to 85 Years
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Marrero, Louisiana
Not listed Not applicable Interventional Accepts healthy volunteers

Accuracy of Pulse Oximeters With Profound Hypoxia

NCT06022523
Conditions
Hypoxemia
Interventions
Data acquisition using DT-400 pulse oximetry system
Diagnostic Test
Lead sponsor
Consolidated Research, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Chronic Low Back Pain, Back Pain
Interventions
Real Acupuncture with Electrical Stimulation, Simulated Acupuncture with Electrical Stimulation
Other
Lead sponsor
Stanford University
Other
Eligibility
21 Years to 65 Years
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Palo Alto, California
Completed Not applicable Interventional Results available

Evaluation of the Nucleus Hybrid™ L24 Cochlear Implant System

NCT00678899
Conditions
Sensorineural Hearing Loss
Interventions
Nucleus Hybrid L24
Device
Lead sponsor
Cochlear
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Accepts healthy volunteers Results available

Profound Dermal and SubQ Cartridges for the Treatment of Cellulite

NCT03078647
Conditions
Cellulite
Interventions
Profound
Device
Lead sponsor
Syneron Medical
Industry
Eligibility
18 Years to 60 Years · Female only
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
2
States / cities
New York, New York • Charlotte, North Carolina