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Showing 1–24 of 67 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Prolapse Repair Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Comparing Postoperative Pain After Vessel Sealing Device Versus Conventional Suturing Methods for Vaginal Hysterectomy and Pelvic Reconstructive Surgery

NCT05192954
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
LigaSureTM vessel sealing device
Device
Lead sponsor
Marlana McDowell
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
2
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 21, 2024 · Synced Sep 5, 2026, 3:55 AM EDT
Completed No phase listed Observational

Dynamic Magnetic Resonance Imaging Before and After Vaginal Prolapse Repair

NCT03315715
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Not listed
Lead sponsor
TriHealth Inc.
Other
Eligibility
18 Years and older · Female only
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 22, 2020 · Synced Sep 5, 2026, 3:55 AM EDT
Terminated Phase 3 Interventional Results available

Effectiveness of Surgical Mitral Valve Repair Versus Medical Treatment for People With Significant Mitral Regurgitation and Non-ischemic Congestive Heart Failure

NCT00608140
View directory record Official record
Conditions
Mitral Valve Insufficiency, Heart Failure
Interventions
Surgical mitral valvuloplasty with placement of annular ring (SMVR), Optimal medical therapy (OMT)
Procedure · Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
8
States / cities
Atlanta, Georgia • Boston, Massachusetts • Minneapolis, Minnesota + 5 more
Source: ClinicalTrials.gov public record
Updated Apr 3, 2018 · Synced Sep 5, 2026, 3:55 AM EDT
Terminated Phase 4 Interventional

Study of the Elevate Anterior and Apical Prolapse Repair System Compared to Native Tissue Repair for Pelvic Organ Prolapse

NCT02121977
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Elevate Anterior and Apical, Native Tissue Repair for pelvic organ prolapse
Device · Procedure
Lead sponsor
ASTORA Women's Health
Industry
Eligibility
18 Years and older · Female only
Enrollment
285 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
31
States / cities
Tucson, Arizona • Beverly Hills, California • Newport Beach, California + 28 more
Source: ClinicalTrials.gov public record
Updated Sep 6, 2016 · Synced Sep 5, 2026, 3:55 AM EDT
Recruiting Not applicable Interventional

BELIEVE Trial: Bulking vErsus sLing for Treating Stress Urinary IncontinEnce at the Time of Vaginal prolapsE Repair (BELIEVE)

NCT06754046
View directory record Official record
Conditions
Stress Urinary Incontinence, Vaginal Prolapse
Interventions
RP-MUS, PAHG
Device · Procedure
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
476 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 31, 2026 · Synced Sep 5, 2026, 3:55 AM EDT
Completed Not applicable Interventional

Graft-Augmented Rectocele Repair-A Randomized Surgical Trial

NCT00321867
View directory record Official record
Conditions
Rectocele
Interventions
Graft augmented posterior repair, Control
Procedure
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
21 Years and older · Female only
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2012
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 16, 2025 · Synced Sep 5, 2026, 3:55 AM EDT
Completed Not applicable Interventional Results available

Abdominal Colpopexy: Comparison of Endoscopic Surgical Strategies

NCT01124916
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Robotic assisted laparoscopic abdominal sacrocolpopexy, Standard laparoscopic abdominal sacrocolpopexy
Procedure
Lead sponsor
Loyola University
Other
Eligibility
18 Years and older · Female only
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
2
States / cities
Los Angeles, California • Maywood, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 3, 2017 · Synced Sep 5, 2026, 3:55 AM EDT
Completed Not applicable Interventional Results available

EVEREST II Pivotal Study High Risk Registry (HRR)

NCT01940120
View directory record Official record
Conditions
Mitral Valve Insufficiency, Mitral Valve Regurgitation, Mitral Valve Incompetence, Mitral Regurgitation, Mitral Insufficiency
Interventions
Percutaneous mitral valve repair using MitraClip implant
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
2
States / cities
Evanston, Illinois • Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Nov 6, 2018 · Synced Sep 5, 2026, 3:55 AM EDT
Completed Not applicable Interventional

Healing Statements and Their Effect on Post Operative Pain

NCT02502357
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Healing Statements
Other
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Aug 20, 2020 · Synced Sep 5, 2026, 3:55 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Axis™ Allograft Dermis for Female Pelvic Floor Repair: a Prospective Post Market Study

NCT01541748
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Axis
Other
Lead sponsor
Coloplast A/S
Industry
Eligibility
18 Years and older · Female only
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2018
U.S. locations
5
States / cities
Weston, Florida • Cambridge, Massachusetts • Grand Rapids, Michigan + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 29, 2020 · Synced Sep 5, 2026, 3:55 AM EDT
Completed No phase listed Observational Results available

Observational Data Collection of Surgical Outcomes in the Treatment of Vaginal Prolapse With AMS Products

NCT00388947
View directory record Official record
Conditions
Vaginal Prolapse
Interventions
AMS Prolapse Product
Device
Lead sponsor
ASTORA Women's Health
Industry
Eligibility
21 Years and older · Female only
Enrollment
1,543 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Whitinsville, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 10, 2016 · Synced Sep 5, 2026, 3:55 AM EDT
Not listed Phase 3 Interventional Accepts healthy volunteers

The Role of 5-Fluorouracil in Post-Operative Scar Formation Following Direct Brow Ptosis Repair

NCT03219580
View directory record Official record
Conditions
Brow Ptosis, Facial Scarring
Interventions
5-Fluorouracil, Normal Saline Flush, 0.9% Injectable Solution
Drug
Lead sponsor
Eyelid and Facial Consultants
Other
Eligibility
40 Years to 90 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
2
States / cities
Houma, Louisiana • New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Jul 25, 2018 · Synced Sep 5, 2026, 3:55 AM EDT
Completed Phase 4 Interventional Results available

Improvement of Pain Following Robotic Sacrocolpopexy and Rectocele Repair for Pelvic Organ Prolapse

NCT02449915
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Bupivacaine, Placebo
Drug
Lead sponsor
TriHealth Inc.
Other
Eligibility
18 Years and older · Female only
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 7, 2017 · Synced Sep 5, 2026, 3:55 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Effect of an Additional Stress Incontinence Procedure on Overactive Bladder During Pelvic Organ Prolapse Repair

NCT02502838
View directory record Official record
Conditions
Overactive Bladder, Pelvic Organ Prolapse
Interventions
Not listed
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
22 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 31, 2017 · Synced Sep 5, 2026, 3:55 AM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Axis(TM) Solvent-dehydrate Dermal Allograft in the Treatment of Pelvic Organ Prolapse.

NCT06263985
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Axis Dermis biologic mesh repair for pelvic organ prolapse
Device
Lead sponsor
Michigan Institution of Women's Health PC
Other
Eligibility
21 Years to 89 Years · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Dearborn, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 15, 2024 · Synced Sep 5, 2026, 3:55 AM EDT
Completed Not applicable Interventional Results available

Prediction of Postsurgical Symptomatic Outcomes With Preoperative Pessary Use

NCT02680145
View directory record Official record
Conditions
Vaginal Vault Prolapse, Pelvic Organ Prolapse, Uterine Prolapse, Pelvic Floor Prolapse
Interventions
Preoperative Pessary Use
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 19, 2020 · Synced Sep 5, 2026, 3:55 AM EDT
Active, not recruiting Not applicable Interventional

Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds (PRIMARY)

NCT05051033
View directory record Official record
Conditions
Mitral Valve Regurgitation
Interventions
Mitral valve repair, Transcatheter edge-to-edge repair
Procedure · Device
Lead sponsor
Annetine Gelijns
Other
Eligibility
60 Years and older
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2030
U.S. locations
24
States / cities
Los Angeles, California • San Francisco, California • Stanford, California + 16 more
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Sep 5, 2026, 3:55 AM EDT
Completed Not applicable Interventional

Laparoscopic Three-dimensional Versus Two-dimensional Sacral Colpopexy and Paravaginal Repair

NCT02258230
View directory record Official record
Conditions
Pelvic Organ Prolapse, Cystocele
Interventions
3D mode of the 3D Laparoscopic Video System, 2D mode of the 3D Laparoscopic Video System
Device
Lead sponsor
Olympus Corporation of the Americas
Industry
Eligibility
18 Years and older · Female only
Enrollment
194 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
2
States / cities
Los Angeles, California • Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 3, 2018 · Synced Sep 5, 2026, 3:55 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Outcomes of Anterior Colporrhaphy Versus Graft Reinforced Anterior Prolapse Repair

NCT00535301
View directory record Official record
Conditions
Cystocele, Uterine Prolapse, Urinary Incontinence
Interventions
grafted anterior prolapse repair, sutured anterior vaginal prolapse repair
Device · Procedure
Lead sponsor
Kaiser Permanente
Other
Eligibility
21 Years and older · Female only
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
1
States / cities
Downey, California
Source: ClinicalTrials.gov public record
Updated Apr 21, 2015 · Synced Sep 5, 2026, 3:55 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Feasibility Study of a Percutaneous Mitral Valve Repair System.

NCT00209339
View directory record Official record
Conditions
Mitral Valve Insufficiency, Mitral Valve Regurgitation, Mitral Valve Incompetence, Mitral Regurgitation, Mitral Insufficiency
Interventions
Percutaneous mitral valve repair (MitraClip Implant)
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2011
U.S. locations
1
States / cities
Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 6, 2018 · Synced Sep 5, 2026, 3:55 AM EDT
Completed Not applicable Interventional

ACell MatriStem Pelvic Floor Matrix Versus Native Tissue Repair, Comparative Study

NCT02021279
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
MatriStem Pelvic Floor Matrix, native tissue repair
Device · Procedure
Lead sponsor
Integra LifeSciences Corporation
Industry
Eligibility
18 Years and older · Female only
Enrollment
161 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
13
States / cities
Stanford, California • Weston, Florida • Grand Rapids, Michigan + 10 more
Source: ClinicalTrials.gov public record
Updated Feb 7, 2022 · Synced Sep 5, 2026, 3:55 AM EDT
Terminated Phase 4 Interventional Results available

The ELEGANT Trial: Elevate Transvaginal Mesh vs. Anterior Colporrhaphy

NCT01497171
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Elevate Mesh, Anterior Colporrhaphy
Procedure
Lead sponsor
Emanuel Trabuco
Other
Eligibility
21 Years to 80 Years · Female only
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
5
States / cities
Roseville, California • Santa Clara, California • Stanford, California + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 20, 2014 · Synced Sep 5, 2026, 3:55 AM EDT
Completed Not applicable Interventional Results available

Barbed Suture Versus Non-Barbed Suture for Posterior Colporrhaphy

NCT04658784
View directory record Official record
Conditions
Rectocele
Interventions
2-0 dioxanone, glycolide and trimethylene carbonate, 2-0 polydioxanone
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older · Female only
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated May 5, 2023 · Synced Sep 5, 2026, 3:55 AM EDT
Completed No phase listed Observational

Robotic-assisted Laparoscopic Sacrocolpopexy

NCT00581334
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Robotic-assisted laparoscopic sacrocolpopexy, Open sacrocolpopexy
Procedure
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Aug 22, 2023 · Synced Sep 5, 2026, 3:55 AM EDT