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ClinicalTrials.gov public records Last synced Oct 8, 2026, 8:25 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–9 of 9 matching trials from the live ClinicalTrials.gov search.

Conditions: Post Traumatic Stress Disorder, Schizophrenia, Schizoaffective Disorder, Bipolar Disorder, Major Depression
Interventions: Prolonged Exposure for PTSD (PE) + Treatment as Usual (TAU), Treatment As Usual (TAU); Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 21 Years and older
Enrollment: 134 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Posttraumatic Stress Disorder
Interventions: Prolonged Exposure for Primary Care (PE-PC), Treatment as Usual; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 2
States / cities: Decatur, Georgia • Charleston, South Carolina

Conditions: Traumatic Injury, PTSD, Posttraumatic Stress Disorder
Interventions: Treatment as Usual, Brief Prolonged Exposure Therapy; Behavioral
Lead sponsor: Baylor Research Institute; Other
Eligibility: 18 Years to 75 Years
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 3
States / cities: Dallas, Texas • Temple, Texas • Milwaukee, Wisconsin

Conditions: Post Traumatic Stress Disorder
Interventions: Prolonged Exposure for Primary Care (PE-PC), EAP Treatment as Usual (TAU); Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 410 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 14
States / cities: San Diego, California • Carrollton, Georgia • Ann Arbor, Michigan + 9 more

Conditions: Opioid Use Disorder, Posttraumatic Stress Disorder
Interventions: Prolonged exposure therapy, Financial incentives, Treatment as usual; Behavioral
Lead sponsor: University of Vermont; Other
Eligibility: 18 Years and older
Enrollment: 135 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Burlington, Vermont

Conditions: Post Traumatic Stress Disorder
Interventions: Quetiapine Fumarate, Standard of care meducations; Drug · Other
Lead sponsor: The University of Texas Health Science Center at San Antonio; Other
Eligibility: 18 Years and older
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Posttraumatic Stress Disorder (PTSD), Substance Use Disorders (SUD), Comorbidity, Trauma and Stressor Related Disorders
Interventions: Massed Prolonged Exposure Therapy (M-PE), Standard outpatient SUD care; Behavioral
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 18 Years and older
Enrollment: 168 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Stress Disorders, Post-Traumatic
Interventions: Adjunctive writing to amplify response and engagement (AWARE), Cognitive processing therapy (CPT), Prolonged exposure (PE); Behavioral
Lead sponsor: Boston University; Other
Eligibility: 18 Years and older
Enrollment: 54 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Boston, Massachusetts

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