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ClinicalTrials.gov public records Last synced Oct 26, 2026, 9:58 AM EDT

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Showing 1–24 of 40 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Prolonged Sitting Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

Breaking up Prolonged Sedentary Behavior to Improve Cardiometabolic Health

NCT05353322
View directory record Official record
Conditions
Sedentary Behavior, Cardiometabolic Risk Factors, Blood Pressure, Glucose
Interventions
Sedentary Break (Walking) Condition, Sitting (Control) Condition, Controlled Diet
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
324 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 9, 2026 · Synced Oct 26, 2026, 9:58 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Interrupting Prolonged Sitting With Periodic Interval Exercise: Effect on Postprandial Lipemia

NCT04241081
View directory record Official record
Conditions
Sedentary Behavior, Hypertriglyceridemia
Interventions
Interrupting Prolonged Sitting with Periodic Interval Exercise: Effect on Postprandial Lipemia
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jan 27, 2020 · Synced Oct 26, 2026, 9:58 AM EDT
Recruiting Not applicable Interventional

Maternal Maneuvers During Prolonged Labor

NCT06636149
View directory record Official record
Conditions
Labor Stage, First, Prolonged Labor
Interventions
Circuit of maternal position changes during labor
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
12 Years and older · Female only
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 26, 2026, 9:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Interrupting Prolonged Sitting With ACTivity (InPACT) at Home Optimization Study

NCT06493214
View directory record Official record
Conditions
Adherence, Treatment, Physical Inactivity
Interventions
Physical activity
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
8 Years to 12 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 26, 2026, 9:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A "Stand Up and Move More" Intervention for Older Adults

NCT03412084
View directory record Official record
Conditions
Sedentary Lifestyle
Interventions
Stand up and move more
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
56 Years and older
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 16, 2020 · Synced Oct 26, 2026, 9:58 AM EDT
Recruiting Not applicable Interventional

Effects of Hourly Stair-Climbing Exercise Snacks on Metabolic and Vascular Health in Adults With Prediabetes

NCT07847684
View directory record Official record
Conditions
Prediabetes
Interventions
Hourly 3-Minute Light Walking Breaks, Hourly Stair-Climbing Exercise Snacks
Behavioral
Lead sponsor
St. Louis University
Other
Eligibility
18 Years to 69 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 26, 2026, 9:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Breaking up Prolonged Sitting on Metabolic Flexibility

NCT02258438
View directory record Official record
Conditions
Health Behavior
Interventions
Uninterrupted sitting, Sitting + 1 bout of activity, Sitting + microbursts of activity
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
19 Years to 45 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 30, 2021 · Synced Oct 26, 2026, 9:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Breathing Interventions for Relaxation: Dosing Through Extended Exhale

NCT02870868
View directory record Official record
Conditions
Healthy Adults, Stress
Interventions
Slow breathing
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
30 Years to 60 Years
Enrollment
99 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 29, 2024 · Synced Oct 26, 2026, 9:58 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Effects of Interrupting Prolonged Sitting With Bouts of Physical Activity on Neurocognitive Function in Obesity

NCT04926207
View directory record Official record
Conditions
Obesity
Interventions
Physical Activity Breaks Intervention, Talking Breaks Control
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
21 Years to 64 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 7, 2024 · Synced Oct 26, 2026, 9:58 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Leg Exercise Assistive Paddling (LEAP) Therapy for Peripheral Artery Disease

NCT06389149
View directory record Official record
Conditions
Peripheral Arterial Disease, Peripheral Vascular Disease, Peripheral Artery Occlusive Disease, Peripheral Artery Disease
Interventions
LEAP therapy, no LEAP therapy
Other
Lead sponsor
University of Nebraska
Other
Eligibility
55 Years to 85 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Aug 21, 2026 · Synced Oct 26, 2026, 9:58 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Soleus H-Reflex in Different Sitting Postures

NCT01744899
View directory record Official record
Conditions
Compression of Spinal Nerve Root, Spinal Disorder, Low Back Pain
Interventions
Sitting posture
Other
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years to 50 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 7, 2012 · Synced Oct 26, 2026, 9:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Osteopathic Manipulative Therapy Effects on Prolonged Post-COVID Olfactory Dysfunction

NCT05112887
View directory record Official record
Conditions
COVID-19 Lower Respiratory Infection, SARS-CoV2 Infection
Interventions
Osteopathic Manipulative Therapy
Other
Lead sponsor
Ohio University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Dublin, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 9, 2021 · Synced Oct 26, 2026, 9:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Prolonged Standing Compared to Prolonged Sitting on Postprandial Lipemia

NCT03089437
View directory record Official record
Conditions
Metabolic Syndrome, Atherosclerosis
Interventions
Prolonged Standing, Prolonged Sitting
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 40 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Oct 4, 2018 · Synced Oct 26, 2026, 9:58 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Breaking Sitting with High-intensity Interval Training for Brain Health

NCT06243016
View directory record Official record
Conditions
Aging
Interventions
High-Intensity Interval Training (HIIT) Breaks to Sitting, Light-Intensity Interval Training (LIIT) Breaks to Sitting
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
40 Years to 75 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 7, 2025 · Synced Oct 26, 2026, 9:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sedentary Behavior Interrupted - A Pilot Study of Acute Interventions on Prolonged Sitting

NCT02743286
View directory record Official record
Conditions
Sedentary Lifestyle
Interventions
Frequent sit-to-stands, Walking breaks, Stand more
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
55 Years and older · Female only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Sep 8, 2016 · Synced Oct 26, 2026, 9:58 AM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers

Enhancing Exposure Therapy for Post-traumatic Stress Disorder

NCT01574118
View directory record Official record
Conditions
Chronic Posttraumatic Stress Disorder
Interventions
Revisiting the Trauma memories, Processing the trauma memories, Psychoeducation, Trauma Memory Retrieval Trial, Exposure to video clips related to the patient's trauma, Breathing retraining, Exposure Homework, Compound extinction
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 65 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2020
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Aug 29, 2022 · Synced Oct 26, 2026, 9:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Optimizing Sedentary Behavior Interventions to Affect Acute Physiological Changes

NCT02544867
View directory record Official record
Conditions
Sedentary Behavior
Interventions
Sedentary behavior
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
50 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Sep 9, 2015 · Synced Oct 26, 2026, 9:58 AM EDT
Completed Not applicable Interventional

A Randomized Controlled Trial of Meditation Compared to Exposure Therapy and Education Control on PTSD in Veterans

NCT01865123
View directory record Official record
Conditions
Post-traumatic Stress Disorder
Interventions
Transcendental Meditation, Prolonged Exposure, Educational control
Behavioral
Lead sponsor
United States Department of Defense
Federal
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Nov 26, 2018 · Synced Oct 26, 2026, 9:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Defy The Odds: Exercise Forecasting and Motivation Strategies for Prolonged-Sitting Jobs

NCT07475130
View directory record Official record
Conditions
Prolonged Sitting
Interventions
Tailored messaging
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
40 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 26, 2026, 9:58 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Move Often eVery Day 2.0

NCT06372327
View directory record Official record
Conditions
Exercise
Interventions
Daily Exercise Snacks
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
30 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Aug 3, 2025 · Synced Oct 26, 2026, 9:58 AM EDT
Recruiting Not applicable Interventional

Exploring the Acute and Dynamic Relationships Between Movement and Pain in Older Adults With Musculoskeletal Pain

NCT06886906
View directory record Official record
Conditions
Older People, Pain
Interventions
Intermittent light walking, uninterrupted sitting
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
55 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 15, 2026 · Synced Oct 26, 2026, 9:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Combined Effects of Prolonged Sitting and Mental Stress on the Cardiovascular System

NCT04207333
View directory record Official record
Conditions
Sedentary Behavior, Cardiovascular Risk Factor, Mental Stress, Cognitive Change, Cerebrovascular Insufficiency
Interventions
Mental Arithmetic Test
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
35 Years to 59 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 18, 2023 · Synced Oct 26, 2026, 9:58 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Lower Leg Compression in Extended Video Game Play: A Pilot Study

NCT05212363
View directory record Official record
Conditions
Compression; Vein, Compression; Artery, Sedentary Behavior, DVT of Legs
Interventions
Lower extremity compression garments, Active break
Device · Behavioral
Lead sponsor
New York Institute of Technology
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Dec 6, 2022 · Synced Oct 26, 2026, 9:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Sitting and Moderate Exercise on Plasma Triglyceride Elevation After a Meal

NCT03098446
View directory record Official record
Conditions
Atherosclerosis, Metabolic Syndrome
Interventions
Prolonged sitting with exercise, Prolonged sitting without exercise
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 40 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Oct 5, 2018 · Synced Oct 26, 2026, 9:58 AM EDT