- Conditions
- Knee Osteoarthritis (OA)
- Interventions
- Participants are given Ibuprofen 400 mg to take for 7 days on the day they receive a dextrose prolotherapy (DPT) injection. These procedures are repeated every 3-5 weeks for a total of 3 times., Participants are given a placebo to take for 7 days on the day they receive a dextrose prolotherapy (DPT) injection. These procedures are repeated every 3-5 weeks for a total of 3 times.
- Drug
- Lead sponsor
- David Grant U.S. Air Force Medical Center
- Federal
- Eligibility
- 45 Years to 75 Years
- Enrollment
- 68 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Travis AFB, California
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Showing 1–11
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- Conditions
- Osteoarthritis
- Interventions
- Dextrose Prolotherapy, Saline Prolotherapy, At-home physical therapy exercise group
- Procedure · Other
- Lead sponsor
- University of Wisconsin, Madison
- Other
- Eligibility
- 40 Years to 70 Years
- Enrollment
- 98 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2016
- U.S. locations
- 2
- States / cities
- Madison, Wisconsin
- Conditions
- Lateral Epicondylitis, Tennis Elbow
- Interventions
- Prolotherapy, Placebo
- Drug · Procedure
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 67 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2011
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Thumb Carpometacarpal Joint Osteoarthritis
- Interventions
- Prolotherapy (10% dextrose solution), Betamethasone
- Drug
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 45 Years and older
- Enrollment
- 2 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2008 – 2010
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Musculoskeletal Pain, Low Back Pain, Myofascial Pain
- Interventions
- Prolotherapy
- Procedure
- Lead sponsor
- ProloAustin
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2022
- U.S. locations
- 1
- States / cities
- Austin, Texas
- Conditions
- Tennis Elbow, Lateral Epicondylitis
- Interventions
- Placebo Injection, Physical Therapy, Corticosteroid Injections, Prolotherapy
- Drug · Behavioral
- Lead sponsor
- Christine M. Kleinert Institute for Hand and Microsurgery
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2019
- U.S. locations
- 1
- States / cities
- Louisville, Kentucky
- Conditions
- Knee Osteoarthritis
- Interventions
- Placebo, Dextrose prolotherapy (DPT)
- Drug
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 40 Years to 80 Years
- Enrollment
- 48 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2025
- U.S. locations
- 1
- States / cities
- Scottsdale, Arizona
- Conditions
- Ehlers-Danlos Syndrome, Low Back Pain, Sacroiliac Instability
- Interventions
- Dextrose 50% Intravenous Solution, Lidocaine 1% Injectable Solution
- Drug
- Lead sponsor
- Tulane University
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- New Orleans, Louisiana
- Conditions
- no Conditions
- Interventions
- Epidural Prolotherapy, Epidural Steroid
- Procedure
- Lead sponsor
- Naveed Natanzi
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2015
- U.S. locations
- 1
- States / cities
- Long Beach, California
- Conditions
- Tennis Elbow
- Interventions
- Dextrose prolotherapy, PrT-DMS, Platelet Rich Plasma injection
- Procedure
- Lead sponsor
- University of Wisconsin, Madison
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 31 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2015
- U.S. locations
- 2
- States / cities
- Madison, Wisconsin
- Conditions
- Lateral Epicondylitis
- Interventions
- Prolotherapy, Local Corticosteroid Therapy
- Drug
- Lead sponsor
- Spaulding Rehabilitation Hospital
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 56 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2005 – 2006
- U.S. locations
- 1
- States / cities
- Wellesley, Massachusetts