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ClinicalTrials.gov public records Last synced Oct 21, 2026, 1:28 AM EDT

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Showing 1–24 of 113 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Propylene Glycol Clear all
Completed Not applicable Interventional Accepts healthy volunteers

A Clinical Study to Evaluate the Efficacy of an Anti-Aging Serum

NCT05271136
View directory record Official record
Conditions
Fine Lines, Wrinkle, Photoaging
Interventions
Anti-aging Serum, Facial Moisturizer, Cleansing Lotion, Sunscreen
Other
Lead sponsor
Revision Skincare
Industry
Eligibility
30 Years to 60 Years · Female only
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Richardson, Texas
Source: ClinicalTrials.gov public record
Updated Mar 8, 2022 · Synced Oct 21, 2026, 1:28 AM EDT
Completed Not applicable Interventional

Systane Complete Multi-symptom Relief

NCT05056155
View directory record Official record
Conditions
Dry Eye Disease
Interventions
Systane Complete
Other
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
4
States / cities
Kansas City, Missouri • Granville, Ohio • Powell, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 29, 2022 · Synced Oct 21, 2026, 1:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Characterization of Nicotine Exposure and Urge-to-Smoke Following Use of Electronic and Conventional Cigarettes

NCT02210754
View directory record Official record
Conditions
Smoking
Interventions
blu™ Classic Tobacco rechargeable (2.4% nicotine, glycerin vehicle), blu™ Classic Tobacco rechargeable (2.4% nicotine, glycerin/PG vehicle), blu™ Magnificent Menthol rechargeable (2.4% nicotine, glycerin vehicle), blu™ Classic Tobacco rechargeable (1.6% nicotine, glycerin vehicle), blu™ Classic Tobacco rechargeable (1.6% nicotine, glycerin/PG vehicle), Marlboro Cigarette
Other
Lead sponsor
Lorillard Tobacco Company
Industry
Eligibility
21 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Lincoln, Nebraska
Source: ClinicalTrials.gov public record
Updated Aug 7, 2014 · Synced Oct 21, 2026, 1:28 AM EDT
Completed Phase 1 Interventional

Fingolimod in Preventing Paclitaxel-Associated Neuropathy in Patients With Breast Cancer

NCT03941743
View directory record Official record
Conditions
Breast Carcinoma
Interventions
Fingolimod, Fingolimod Hydrochloride, Questionnaire Administration
Drug · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
3
States / cities
Rochester, Minnesota • Columbus, Ohio • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 21, 2023 · Synced Oct 21, 2026, 1:28 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Airway Alkalinization and Nasal Colonization

NCT03078088
View directory record Official record
Conditions
Healthy Subjects, Cystic Fibrosis
Interventions
Tham, Saline
Drug
Lead sponsor
Lakshmi Durairaj
Other
Eligibility
16 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Mar 30, 2020 · Synced Oct 21, 2026, 1:28 AM EDT
Completed Phase 3 Interventional Results available

Long-term Safety and Tolerability of 0.5 mg Fingolimod in Patients With Relapsing Forms of Multiple Sclerosis

NCT01201356
View directory record Official record
Conditions
Relapsing Forms of Multiple Sclerosis
Interventions
Fingolimod
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
4,125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2018
U.S. locations
34
States / cities
Cullman, Alabama • Oceanside, California • Sacramento, California + 30 more
Source: ClinicalTrials.gov public record
Updated Apr 21, 2021 · Synced Oct 21, 2026, 1:28 AM EDT
Recruiting Phase 2 Interventional

Phase 2 Study of Fingolimod in Lung Cancers

NCT06424067
View directory record Official record
Conditions
Non Small Cell Lung Cancer, Small-cell Lung Cancer
Interventions
Fingolimod 0.5 milligram (mg) [Gilenya]
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Oct 21, 2026, 1:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Comparative Split-Face Study of the Effects of a Retinol Alternative Cream on Improving Facial Skin Aging

NCT06125912
View directory record Official record
Conditions
Skin Aging
Interventions
Dime Beauty TBT Cream, Positive Control
Other
Lead sponsor
Dime Beauty Co.
Industry
Eligibility
18 Years to 65 Years · Female only
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Feb 22, 2024 · Synced Oct 21, 2026, 1:28 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Post-Operative Constipation Following Total Knee Arthroplasty

NCT04380090
View directory record Official record
Conditions
Constipation
Interventions
Propylene Glycol, Docusate Sodium
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
20 Years to 90 Years
Enrollment
154 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 19, 2022 · Synced Oct 21, 2026, 1:28 AM EDT
Recruiting Phase 3 Interventional

Study to Evaluate the Effectiveness and Safety of Ozanimod Compared to Fingolimod in Children and Adolescents With Relapsing Remitting Multiple Sclerosis

NCT06408259
View directory record Official record
Conditions
Multiple Sclerosis, Relapsing-Remitting
Interventions
Ozanimod, Fingolimod, Placebo
Drug · Other
Lead sponsor
Bristol-Myers Squibb
Industry
Eligibility
10 Years to 17 Years
Enrollment
194 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2036
U.S. locations
12
States / cities
Loma Linda, California • Sacramento, California • Tampa, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 21, 2026, 1:28 AM EDT
Completed Phase 4 Interventional Results available

A 6-month, Randomized, Open-label, Patient OutComes, Safety and Tolerability Study of Fingolimod (FTY720) 0.5 mg/Day vs. Comparator in Patients With Relapsing Forms of Multiple Sclerosis

NCT01216072
View directory record Official record
Conditions
Relapsing Forms of Multiple Sclerosis
Interventions
Fingolimod, Standard MS DMTs
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years to 65 Years
Enrollment
1,053 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
142
States / cities
Birmingham, Alabama • Cullman, Alabama • Phoenix, Arizona + 125 more
Source: ClinicalTrials.gov public record
Updated Feb 10, 2014 · Synced Oct 21, 2026, 1:28 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

A Study to Assess Efficacy and Tolerability of Topical Skincare Products on Psoriasis Patients

NCT06357221
View directory record Official record
Conditions
Plaque Psoriasis, Psoriasis
Interventions
Cetaphil
Drug
Lead sponsor
Galderma R&D
Industry
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
3
States / cities
Columbus, Georgia • Douglasville, Georgia • High Point, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 21, 2026, 1:28 AM EDT
Completed Not applicable Interventional Results available

Duration of Effect of Biotene Spray in Patients With Dry Mouth

NCT03663231
View directory record Official record
Conditions
Dry Mouth
Interventions
Biotene, Placebo
Device
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jan 20, 2021 · Synced Oct 21, 2026, 1:28 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Safety and Pharmacokinetics Study of CARD-024 in Healthy Subjects

NCT01757860
View directory record Official record
Conditions
Drug Safety, Heart; Disease, Activity
Interventions
CARD-024, Drug Carrier
Drug · Other
Lead sponsor
Cardiavent Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Kalamazoo, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 31, 2012 · Synced Oct 21, 2026, 1:28 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Evaluation of Acute and Subacute Effects of Nicotine Free Electronic Cigarette(NCFE) Vapors

NCT02585791
View directory record Official record
Conditions
Healthy Lifetime Non-smokers
Interventions
Propylene Glycol, vegetable glycerin, PG+VG
Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jan 14, 2020 · Synced Oct 21, 2026, 1:28 AM EDT
Recruiting Phase 4 Interventional

A Study of Tris-Hydroxymethyl Aminomethane (THAM) Versus Sodium Bicarbonate in Cardiac Surgical Patients

NCT07424625
View directory record Official record
Conditions
Metabolic Acidosis
Interventions
Sodium bicarbonate, Tris-hydroxymethyl Aminomethane
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
21 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 21, 2026, 1:28 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Effects of FTY720 on Heart and Lung Functions in Healthy Volunteers

NCT00416845
View directory record Official record
Conditions
Healthy
Interventions
FTY720
Drug
Lead sponsor
Novartis
Industry
Eligibility
19 Years to 50 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2006
U.S. locations
1
States / cities
East Hanover, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 4, 2010 · Synced Oct 21, 2026, 1:28 AM EDT
Completed Phase 2 Interventional Results available

Study of Melphalan HCl for Injection (Propylene Glycol-free), Carmustine, Etoposide, Cytarabine (BEAM Regimen) and Autologous Stem Cell Transplantation for Lymphoma

NCT01969435
View directory record Official record
Conditions
Hodgkin Disease, Lymphoma, Non-Hodgkin
Interventions
Carmustine, Etoposide phosphate, Cytarabine, Melphalan HCl (propylene glycol-free)
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 75 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 13, 2018 · Synced Oct 21, 2026, 1:28 AM EDT
Completed Not applicable Interventional Results available

Testing the Effect of ENDS Flavors on Neurotransmission

NCT05836051
View directory record Official record
Conditions
Tobacco Dependence
Interventions
Flavor
Other
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
21 Years to 60 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 7, 2026 · Synced Oct 21, 2026, 1:28 AM EDT
Completed Phase 2Phase 3 Interventional

Safety and Efficacy of FTY720 in Adult Patients Who Receive a Kidney Transplant

NCT00099749
View directory record Official record
Conditions
Kidney Transplantation
Interventions
FTY 720
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years to 65 Years
Enrollment
255 participants
Timeline
Started 2003
U.S. locations
5
States / cities
Maywood, Illinois • Springfield, Illinois • Livingston, New Jersey + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 23, 2017 · Synced Oct 21, 2026, 1:28 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Protective Effects of Propylene Glycol in Daily Acetaminophen Dosing

NCT02322879
View directory record Official record
Conditions
Acetaminophen Toxicity
Interventions
First Treatment Period, Washout, Second Treatment Period
Drug · Other
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
20 Years to 40 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 1, 2017 · Synced Oct 21, 2026, 1:28 AM EDT
Suspended Phase 1Phase 2 Interventional

Vitamin D and Bone Homeostasis in Ortho Polytrauma Patients

NCT03066817
View directory record Official record
Conditions
Vitamin D Deficiency, Polytrauma, Orthopedic Disorder
Interventions
Ergocalciferol 8000 IU/ML Oral Liquid [DRISDOL], Propylene Glycol
Drug
Lead sponsor
New York City Health and Hospitals Corporation
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Apr 4, 2019 · Synced Oct 21, 2026, 1:28 AM EDT
Terminated Not applicable Interventional Results available

Hydrogel Patch for the Treatment of Eczema

NCT00924508
View directory record Official record
Conditions
Eczema
Interventions
hydrogel patch, Triamcinolone (TAC) 0.1% cream
Device · Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 31, 2014 · Synced Oct 21, 2026, 1:28 AM EDT
Completed Phase 1 Interventional

Intravitreal Ketorolac for Chronic Uveitis: A Investigational Safety Study

NCT01164085
View directory record Official record
Conditions
Inflammation
Interventions
Intravitreal Ketorolac
Drug
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years to 90 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 31, 2013 · Synced Oct 21, 2026, 1:28 AM EDT