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ClinicalTrials.gov public records Last synced Oct 22, 2026, 2:06 AM EDT

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Showing 1–24 of 30 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Prostate biopsy needle Clear all
Recruiting Not applicable Interventional

5-Alpha Reductase 2 as a Marker of Resistance to 5ARI Therapy

NCT04288427
View directory record Official record
Conditions
Benign Prostatic Hyperplasia, Prostate Hyperplasia, Prostate Disease, Prostate Hypertrophy, Prostate Pain, Lower Urinary Tract Symptoms, Urinary Obstruction, Urinary Tract Disease
Interventions
Finasteride
Drug
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
50 Years and older · Male only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 28, 2025 · Synced Oct 22, 2026, 2:06 AM EDT
Recruiting Phase 3 Interventional

A Study of Changes to Prostate Procedures

NCT06986083
View directory record Official record
Conditions
Prostate Cancer
Interventions
Prostate Biopsy, Local anesthesia
Procedure · Drug
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Male only
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 22, 2026, 2:06 AM EDT
Recruiting Not applicable Interventional

Evaluation of the Performance of a Novel Prostate Biopsy System Compared With Standard of Care Biopsy Needle on Quantitative and Qualitative Tissue Parameters

NCT05470127
View directory record Official record
Conditions
Prostate Disease, Prostate CA
Interventions
Prostate biopsy needle
Device
Lead sponsor
Uro-1 Medical
Industry
Eligibility
18 Years to 90 Years · Male only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Cartersville, Georgia
Source: ClinicalTrials.gov public record
Updated May 7, 2025 · Synced Oct 22, 2026, 2:06 AM EDT
Recruiting Not applicable Interventional

MRI Guided Prostate Biopsy

NCT06302595
View directory record Official record
Conditions
Suspected Prostate Cancer
Interventions
MRI-guided prostate biopsy using the needle holder frame.
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
30 Years and older · Male only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 3, 2025 · Synced Oct 22, 2026, 2:06 AM EDT
Enrolling by invitation Not applicable Interventional

A Study of Optical Fusion Trans-Perineal Grid

NCT05573048
View directory record Official record
Conditions
Prostate Biopsy
Interventions
Trans-Perineal Grid
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
45 Years and older · Male only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 14, 2026 · Synced Oct 22, 2026, 2:06 AM EDT
Completed Not applicable Interventional

Pilot Study on Focal Prostate Radio-Frequency Ablation

NCT01423006
View directory record Official record
Conditions
Prostate Cancer
Interventions
Radio-Frequency Ablation (RFA) ENCAGE™
Procedure
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older · Male only
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Nov 14, 2013 · Synced Oct 22, 2026, 2:06 AM EDT
Completed Not applicable Interventional

Prostate Biopsy, Transrectal vs. Transperineal: Efficacy and Complications

NCT04081636
View directory record Official record
Conditions
Prostate Cancer, PSA, Infection
Interventions
Systematic Transrectal biopsy (TR-Bx), Targeted Transrectal biopsy (TR-Bx), Systematic Transperineal biopsy (TP-Bx), Targeted Transperineal biopsy (TP-Bx)
Procedure
Lead sponsor
Albany Medical College
Other
Eligibility
Male only
Enrollment
840 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Oct 22, 2026, 2:06 AM EDT
Completed Not applicable Interventional Results available

PReclude Infection EVEnts With No Prophylaxis Transperineal Biopsy 2

NCT04815876
View directory record Official record
Conditions
Infection
Interventions
Transperineal MRI-guided prostate biopsy, Transrectal MRI-guided prostate biopsy, Antibiotic (prophylaxis)
Procedure · Drug
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older · Male only
Enrollment
1,040 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
16
States / cities
Los Angeles, California • Farmington, Connecticut • Washington D.C., District of Columbia + 11 more
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Oct 22, 2026, 2:06 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Decision Impact Trial of the ExoDx Prostate (IntelliScore)

NCT03235687
View directory record Official record
Conditions
Cancer of the Prostate
Interventions
ExoDx Prostate (IntelliScore)
Diagnostic Test
Lead sponsor
Exosome Diagnostics, Inc.
Industry
Eligibility
50 Years and older · Male only
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
1
States / cities
Towson, Maryland
Source: ClinicalTrials.gov public record
Updated May 6, 2022 · Synced Oct 22, 2026, 2:06 AM EDT
Not listed Phase 2 Interventional

PSMA PET Scan and mpMRI for Prostate Cancer Detection

NCT05820724
View directory record Official record
Conditions
Prostate Cancer Diagnosis
Interventions
PSMA PET scan, No PSMA PET, 18F- DCFPyl Injection
Diagnostic Test · Other · Drug
Lead sponsor
VA Greater Los Angeles Healthcare System
Federal
Eligibility
18 Years and older · Male only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 24, 2023 · Synced Oct 22, 2026, 2:06 AM EDT
Recruiting No phase listed Observational

Interstitial Assessment of Architectural Heterogeneity in Prostate Cancer Using a Fine Needle Photoacoustic Probe

NCT05965180
View directory record Official record
Conditions
Prostate Cancer
Interventions
Fine Needle Photoacoustic Probe
Device
Lead sponsor
University of Michigan Rogel Cancer Center
Other
Eligibility
40 Years to 80 Years · Male only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 24, 2025 · Synced Oct 22, 2026, 2:06 AM EDT
Completed Phase 1 Interventional

C-11 Choline PET-CT Scan in Finding Metastases in Patients With Newly Diagnosed High-Risk Prostate Cancer

NCT00804245
View directory record Official record
Conditions
Prostate Cancer
Interventions
needle biopsy, PET-CT scans supplemented with 11C-Choline tracer
Procedure · Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
30 Years to 120 Years · Male only
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 3, 2018 · Synced Oct 22, 2026, 2:06 AM EDT
Completed Phase 2 Interventional Results available

Sorafenib Tosylate and Gene Expression Analysis in Patients Undergoing Surgery For High-Risk Localized Prostate Cancer

NCT00466752
View directory record Official record
Conditions
Adenocarcinoma of the Prostate, Stage II Prostate Cancer, Stage III Prostate Cancer
Interventions
sorafenib tosylate, microarray analysis, immunohistochemistry staining method, gene expression analysis, needle biopsy, therapeutic conventional surgery, laboratory biomarker analysis, western blotting, RNA analysis
Drug · Genetic · Other + 1 more
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older · Male only
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Nov 22, 2017 · Synced Oct 22, 2026, 2:06 AM EDT
Completed Phase 3 Interventional

BAYQ3939, 1000 mg Tablet in Transrectal Needle Biopsies of the Prostate (TRNBP) - Infection Prophylaxis

NCT00670215
View directory record Official record
Conditions
Bacterial Infections
Interventions
Ciprofloxacin single dose, Ciprofloxacin triple dose
Drug
Lead sponsor
Bayer
Industry
Eligibility
18 Years and older · Male only
Enrollment
497 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004
U.S. locations
18
States / cities
Birmingham, Alabama • San Diego, California • San Francisco, California + 15 more
Source: ClinicalTrials.gov public record
Updated Dec 19, 2014 · Synced Oct 22, 2026, 2:06 AM EDT
Not listed No phase listed Observational

Identification of Clinically Insignificant or Significant Prostate Cancer With the miR Scientific Sentinel™ Platform

NCT04100811
View directory record Official record
Conditions
Prostate Cancer
Interventions
Not listed
Lead sponsor
miR Scientific LLC
Industry
Eligibility
45 Years and older · Male only
Enrollment
2,019 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
3
States / cities
Atlanta, Georgia • Stockbridge, Georgia • Farmingdale, New York
Source: ClinicalTrials.gov public record
Updated Oct 25, 2023 · Synced Oct 22, 2026, 2:06 AM EDT
Completed Not applicable Interventional Results available

PReclude Infection EVEnts With No Prophylaxis Transperineal Biopsy

NCT04843566
View directory record Official record
Conditions
Infection
Interventions
Transperineal MRI-guided prostate biopsy, Transrectal MRI-guided prostate biopsy, Antibiotic (prophylaxis)
Procedure · Drug
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older · Male only
Enrollment
687 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
10
States / cities
Farmington, Connecticut • Washington D.C., District of Columbia • Chicago, Illinois + 6 more
Source: ClinicalTrials.gov public record
Updated Apr 15, 2025 · Synced Oct 22, 2026, 2:06 AM EDT
Completed Not applicable Interventional

Early Staged Consent Before Prostate Biopsy

NCT03507725
View directory record Official record
Conditions
Prostate Cancer
Interventions
Meditation, Prostate Biopsy, Questionnaires
Behavioral · Procedure
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
Male only
Enrollment
390 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 16, 2024 · Synced Oct 22, 2026, 2:06 AM EDT
Completed Phase 2 Interventional Results available

Targeted Fusion Biopsy of the Prostate

NCT02744534
View directory record Official record
Conditions
Prostatic Neoplasms
Interventions
FACBC PET-CT Scan, Three-dimensional ultrasound-guided biopsy, Standard transrectal ultrasound (TRUS) guided biopsy
Drug · Procedure
Lead sponsor
Emory University
Other
Eligibility
18 Years and older · Male only
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated May 8, 2019 · Synced Oct 22, 2026, 2:06 AM EDT
Not listed Not applicable Interventional

Assessment of VMCore Biopsy Versus Standard of Care Biopsy

NCT04982536
View directory record Official record
Conditions
Prostate Cancer
Interventions
VMCore Biopsy System, Standard of Care Biopsy Needle
Device
Lead sponsor
Uro-1 Medical
Industry
Eligibility
18 Years and older · Male only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Cartersville, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 29, 2021 · Synced Oct 22, 2026, 2:06 AM EDT
Recruiting Phase 2 Interventional

An Evidence-Based Focal Cryotherapy Protocol for Focal Ablation of Intermediate Risk Prostate Cancer

NCT05454488
View directory record Official record
Conditions
Prostate Cancer
Interventions
Focal Cryoablation, Standard of Care, Quality-of-life Questionnaires
Drug · Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older · Male only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Oct 22, 2026, 2:06 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Clinical Evaluation of the 'ExoDx Prostate IntelliScore' (EPI)

NCT03031418
View directory record Official record
Conditions
Cancer of Prostate
Interventions
ExoDx Prostate Intelliscore
Diagnostic Test
Lead sponsor
Exosome Diagnostics, Inc.
Industry
Eligibility
50 Years and older · Male only
Enrollment
532 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
18
States / cities
Fort Myers, Florida • Miami, Florida • Macon, Georgia + 12 more
Source: ClinicalTrials.gov public record
Updated Dec 29, 2020 · Synced Oct 22, 2026, 2:06 AM EDT
Recruiting Not applicable Interventional

Comparison of New SUREcore Biopsy of Needle to Standard of Care During Transperineal Prostate Biopsies

NCT06907446
View directory record Official record
Conditions
Prostate Cancer
Interventions
Comparison of Biopsy Needle Types for Prostate Biopsy
Diagnostic Test
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older · Male only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 22, 2026, 2:06 AM EDT
Recruiting Not applicable Interventional

Comparing Standard of Care Biopsy System to a Novel Biopsy Needle System by Computational Pathologic Analysis

NCT06830265
View directory record Official record
Conditions
Prostate Cancer Screening
Interventions
Novel needle biopsy catheter (test)
Device
Lead sponsor
Uro-1 Medical
Industry
Eligibility
18 Years and older · Male only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
3
States / cities
New York, New York • Durham, North Carolina • Hardeeville, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 22, 2026, 2:06 AM EDT
Completed Not applicable Interventional

Magnetic Resonance Imaging to Locate and Characterize Prostate Cancer

NCT00082147
View directory record Official record
Conditions
Prostate Cancer
Interventions
Biopsy
Procedure
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years to 90 Years · Male only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2018
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 13, 2018 · Synced Oct 22, 2026, 2:06 AM EDT