Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Sep 5, 2026, 6:15 PM EDT

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Showing 1–24 of 278 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Progressive Multiple Sclerosis, Depression
Interventions
Virtual Reality, Standard care
Device · Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Completed Not applicable Interventional Accepts healthy volunteers Results available

Dispensing Evaluation of Investigational Contact Lenses

NCT02625220
Conditions
Myopia; Astigmatism
Interventions
Prototype toric lens senofilcon A
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
177 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
12
States / cities
Jacksonville, Florida • Pembroke Pines, Florida • Winter Park, Florida + 9 more
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Delayed Heterologous SARS-CoV-2 Vaccine Dosing (Boost) After Receipt of EUA Vaccines

NCT04889209
Conditions
COVID-19
Interventions
Ad26.COV2.S, BNT162b2, mRNA-1273, mRNA-1273.211, mRNA-1273.222, SARS-CoV-2 rS/M1
Biological
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
18 Years to 99 Years
Enrollment
867 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
10
States / cities
Decatur, Georgia • Baltimore, Maryland • New York, New York + 6 more
Conditions
Atrial Fibrillation
Interventions
CardiaCare RR2, Sham Device
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
New York, New York
Conditions
Feasibility, Diet, Healthy
Interventions
Super Chef: Family Fun in the Kitchen!
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
10 Years to 65 Years
Enrollment
88 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Houston, Texas
Conditions
Cancer, Cancer Pain, Chronic Cancer Pain
Interventions
VR-CAN prototype chronic cancer pain therapy -- virtual reality program delivering CBT for chronic cancer pain management, Active Control -- two-dimensional tablet-delivered intervention
Device
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Durham, North Carolina
Conditions
COVID19
Interventions
Control swab, Prototype swab
Device
Lead sponsor
University of Virginia
Other
Eligibility
0 Years to 99 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Charlottesville, Virginia
Conditions
Amputation
Interventions
Pump prototype
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Amputation
Interventions
Hybrid Leg, Prescribed Passive Prosthesis
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 95 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Completed Not applicable Interventional Accepts healthy volunteers

Determination of the Oral Irritation Potential of a Fluoride Rinse in Children

NCT06798441
Conditions
Healthy
Interventions
Brush Only, Brush / Rinse (Jolly Rancher Prototype), Brush / Rinse (LISTERINE® Total Care Zero Alcohol)
Other
Lead sponsor
Johnson & Johnson Consumer and Personal Products Worldwide
Industry
Eligibility
6 Years to 11 Years
Enrollment
161 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Fort Wayne, Indiana
Conditions
Acute Ischemic Stroke
Interventions
C-Arm Cone Beam Computed Tomography
Diagnostic Test
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 99 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Madison, Wisconsin
Conditions
Knee Osteoarthritis
Interventions
normal activities and clinical care, Concentric Focused Resistance Exercise, Eccentric Focused Resistance Exercise
Other
Lead sponsor
University of Florida
Other
Eligibility
60 Years to 85 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Gainesville, Florida
Not listed No phase listed Observational Accepts healthy volunteers

Refining Information Technology Support for Genetics in Medicine

NCT01225978
Conditions
Hypertrophic Cardiomyopathy, Hearing Loss, Cancer
Interventions
GeneInsight Clinic (GIC)
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
Not listed
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
8
States / cities
Boston, Massachusetts • Ann Arbor, Michigan
Conditions
Skin Laxity
Interventions
Ulthera Treatment at EL2, Ulthera Treatment at EL4
Device
Lead sponsor
Ulthera, Inc
Industry
Eligibility
30 Years to 65 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
3
States / cities
Beverly Hills, California • Saratoga, California • Wilmington, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Performance of Senofilcon A Investigational Lens

NCT05300763
Conditions
Visual Acuity
Interventions
senofilcon A prototype, Dailies Total 1
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
344 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
19
States / cities
San Francisco, California • Jacksonville, Florida • Longwood, Florida + 13 more
Conditions
Epilepsy
Interventions
ProGuardian
Device
Lead sponsor
Cyberonics, Inc.
Industry
Eligibility
5 Years and older
Enrollment
147 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
6
States / cities
Chicago, Illinois • Charlotte, North Carolina • Austin, Texas + 2 more
Completed No phase listed Observational Accepts healthy volunteers Results available

Evaluation of an Open-source Speech-processing Platform

NCT03686046
Conditions
Hearing Loss, Sensorineural
Interventions
Exploratory use
Other
Lead sponsor
San Diego State University
Other
Eligibility
30 Years to 90 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
San Diego, California
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
Breathing Awareness
Other
Lead sponsor
Minnesota HealthSolutions
Industry
Eligibility
40 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Arthritis, Rheumatoid
Interventions
CP 690,550 oral solutions
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 75 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Woburn, Massachusetts
Conditions
Smoking
Interventions
smokeSCREEN game
Behavioral
Lead sponsor
Yale University
Other
Eligibility
10 Years to 16 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
4
States / cities
Hamden, Connecticut • New Haven, Connecticut
Conditions
Pancreas Cancer
Interventions
semistructured interviews, feedback
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Chapel Hill, North Carolina • Milwaukee, Wisconsin
Conditions
Migraine Disorders
Interventions
MigraineManager: Individualized Self-Management Tool
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
11 Years to 18 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2026
U.S. locations
1
States / cities
Cincinnati, Ohio
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

DECIDE: Dyads and Families

NCT05139290
Conditions
Dementia, Alzheimer Disease, Caregiver Burden
Interventions
Prototype Intervention
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
4
States / cities
Washington D.C., District of Columbia • Atlanta, Georgia
Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
TARA v3.1, only non-pharmacological self-management support, TARA v3.2, both non-pharmacological and pharmacological self-management support
Device
Lead sponsor
Boehringer Ingelheim
Industry
Eligibility
40 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
2
States / cities
Gastonia, North Carolina • Charleston, South Carolina