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ClinicalTrials.gov public records Last synced Nov 15, 2026, 2:24 AM EST

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Showing 1–24 of 59 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Psychoeducation and Relaxation Training (RELAX) Clear all

Conditions: Anxiety Disorders
Interventions: Progressive Muscle Relaxation, Diaphragmatic Breathing, Psychoeducation (Placebo); Behavioral · Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 60 Years and older
Enrollment: 56 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Elevated Anxiety Sensitivity
Interventions: Standard Exposure, Stress Management Training, Enhanced Exposure; Behavioral
Lead sponsor: University of Texas at Austin; Other
Eligibility: 18 Years to 70 Years
Enrollment: 399 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 5
States / cities: Boulder, Colorado • Miami, Florida • Boston, Massachusetts + 2 more

Conditions: Misophonia
Interventions: Acceptance and commitment therapy, Progressive relaxation training; Behavioral
Lead sponsor: Utah State University; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Logan, Utah

Conditions: Triple Negative Breast Cancer (TNBC)
Interventions: RESTORE, Enhanced Usual Care; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Dental Phobia, Dental Anxiety in Children, Dental Fear, Dental Fear and Anxiety
Interventions: One-Session Treatment for Dental Phobia (OSTD), Psychoeducation and Relaxation Training (RELAX); Behavioral
Lead sponsor: University of Texas Rio Grande Valley; Other
Eligibility: 7 Years to 16 Years
Enrollment: 160 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 2
States / cities: Brownsville, Texas • Edinburg, Texas

Conditions: Anger, Smoking Cessation
Interventions: Anger Reduction Treatment, Control Condition; Behavioral
Lead sponsor: Florida State University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Tallahassee, Florida

Conditions: Hematopoietic/Lymphoid Cancer
Interventions: Paced respiration as part of PEPRR, PEPRR; Device · Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years and older
Enrollment: 298 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2013
U.S. locations: 2
States / cities: Aurora, Colorado • Denver, Colorado

Conditions: Trauma, Psychological, Trauma and Stressor Related Disorders
Interventions: Trauma-Focused Cognitive Behavioral Therapy (TF-CBT), School-Adapted TF-CBT (S-TF); Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 7 Years and older
Enrollment: 102 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Schizophrenia, Serious Mental Illness
Interventions: Engaging in Community Roles and Experiences (ENCoRE), Health & Wellness (H&W); Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 75 Years
Enrollment: 105 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Anxiety, Depression, Unspecified Adult Solid Tumor, Protocol Specific, Cancer, Cognitive Behavioral Therapy
Interventions: Brief Cognitive Behavioral Therapy; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 49 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Advanced Lung Cancer, Dyspnea
Interventions: Dyspnea Intervention, Enhanced Usual Care; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 420 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 2
States / cities: Coral Gables, Florida • Boston, Massachusetts

Conditions: Depression, Parkinson's Disease
Interventions: TH-CBT, Enhanced Usual Care; Behavioral · Other
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 35 Years to 85 Years
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Piscataway, New Jersey

Conditions: Anger, Suicidal Ideation
Interventions: Anger Reduction Treatment, Progressive Muscle Relaxation, Control Condition; Behavioral
Lead sponsor: Florida State University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Tallahassee, Florida

Conditions: Chronic Low Back Pain
Interventions: Distraction-Based VR, Sham VR, Skills-Based VR, Activity Tracker; Device
Lead sponsor: Cedars-Sinai Medical Center; Other
Eligibility: 13 Years and older
Enrollment: 413 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Substance Use Disorders
Interventions: Distress Tolerance - Benzodiazepine Discontinuation (DT-BD), Relaxation Therapy; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years and older
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022
U.S. locations: 3
States / cities: Pittsburgh, Pennsylvania • Wilkinsburg, Pennsylvania

Conditions: Misophonia
Interventions: Unified Protocols for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents (UP-C/A) for youth with misophonia, Psychoeducation and Relaxation Therapy (PRT); Behavioral
Lead sponsor: University of South Florida; Other
Eligibility: 8 Years to 16 Years
Enrollment: 124 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 2
States / cities: Coral Gables, Florida • St. Petersburg, Florida

Conditions: Suicide, Suicidal Ideation, Suicide Attempt
Interventions: Brief Cognitive Behavioral Therapy (BCBT), Present-Centered Therapy (PCT); Behavioral
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older
Enrollment: 98 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Substance Use Disorders
Interventions: Distress Tolerance - Benzodiazepine Discontinuation (DT-BD), BZD discontinuation protocol; Behavioral · Drug
Lead sponsor: Boston Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: IBS - Irritable Bowel Syndrome, IBD - Inflammatory Bowel Disease
Interventions: MIndful Jazz, Reggae Stereotypes, Traditional Mindfulness, Pain psychoeducation; Behavioral
Lead sponsor: University of California, Irvine; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Orange, California

Conditions: Older Adults (65 Years and Older)
Interventions: Cognitive-behavioral therapy for insomnia, Sleep hygiene education; Behavioral
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 60 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Newark, New Jersey

Conditions: Insomnia
Interventions: Internet-based Self-help Insomnia Intervention; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 77 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: West Haven, Connecticut

Conditions: Post-Concussion Syndrome
Interventions: Usual Care, C-STEP (Cognitive Behavioral Therapy); Behavioral
Lead sponsor: Sean Rose; Other
Eligibility: 10 Years to 18 Years
Enrollment: 37 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: PTSD, Signs and Symptoms, Respiratory
Interventions: Relaxation Response Resiliency Program (3RP), Health Enhancement Program (HEP); Behavioral
Lead sponsor: Stony Brook University; Other
Eligibility: 18 Years and older
Enrollment: 157 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Stony Brook, New York

Conditions: Fundamental Adaptive Skills Training, Relaxation and Mindfulness Training
Interventions: Fundamental Adaptive Skills Training, Relaxation and Mindfulness Training; Behavioral
Lead sponsor: Florida State University; Other
Eligibility: 18 Years and older
Enrollment: 105 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Tallahassee, Florida

Search by objective public record fields.

Anxiety in Older Veterans

Exposure Therapy Consortium (ETC) for Anxiety Sensitivity

Psychological Intervention for Misophonia

A Nurse-Led, Coping and Supportive Intervention for Patients With Triple-Negative Breast Cancer

Study of Anxiety Free Experiences at the Dentist

Computerized Anger-Reduction Treatment for Smoking Cessation

Stress Management Intervention for Caregivers of Patients Undergoing Bone Marrow Transplant (BMT)

Systematic Redesign of Trauma-Focused Cognitive Behavioral Therapy (TF-CBT)

Improving Negative Symptoms & Community Engagement in Veterans With Schizophrenia

Brief CBT for Anxiety and Advanced Cancer

Multi-site Trial of a Brief Behavioral Intervention for Dyspnea in Patients With Advanced Lung Cancer

Telephone-Based Counseling for Depression in Parkinson's Disease

Controlled Evaluation of a Computerized Anger-reduction Treatment for Suicide Prevention

Virtual Reality Therapy for Chronic Low Back Pain

Distress Tolerance for Benzodiazepine Discontinuation

Treatment for Youth (Ages 8 to 16 Years Old) With Misophonia (U-HEAR)

A Randomized Clinical Trial Testing the Effectiveness of Telemental Health for Suicidal Patients

Benzodiazepine Discontinuation in Opioid Agonist Therapy

Relaxation Music for Chronic Pain

CBT-I in Older African American Adults

Implementing and Evaluating Computer-Based Interventions for Mental Health: Testing an Implementation Strategy for VA Outpatient Care

Concussion Symptom Treatment and Education Program (C-STEP) in Post-Concussion Syndrome

Stress Management Program for World Trade Center (WTC) Responders

The Fundamental Adaptive Skills Training