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Conditions: PTSD - Post Traumatic Stress Disorder, PTSD (Childbirth-Related)
Interventions: Narrative Exposure Therapy (NET); Behavioral
Lead sponsor: Indiana University; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 106 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Stress, Anxiety
Interventions: PRISM Program Video Coach, PRISM Program Text Coach, mPRISM Program App; Behavioral
Lead sponsor: Dana-Farber Cancer Institute; Other
Eligibility: 12 Years to 25 Years
Enrollment: 325 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 2
States / cities: Boston, Massachusetts

Conditions: Adherence to Physical Activity After Completing Cardiac Rehabilitation (CR) in Older Adults
Interventions: Virtual Coaching and social support; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 55 Years to 100 Years
Enrollment: 286 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Hematologic Malignancy, Stem Cell Transplant, Bone Marrow Transplant, Leukemia, Lymphoma, Multiple Myeloma, Myelodysplastic Syndromes
Interventions: Intervention website, Enhanced Usual Care (Control) Website; Behavioral
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older
Enrollment: 356 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2030
U.S. locations: 3
States / cities: Washington D.C., District of Columbia • Chicago, Illinois • Nutley, New Jersey

Conditions: Self-Control
Interventions: Cold-Pressor Task (CPT), Trier Social Stress Test (TSST), Modified Non-Stress CPT, Modified Non-Stress TSST, Functional Magnetic Resonance Imaging (fMRI); Behavioral · Device
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 70 Years
Enrollment: 300 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: New York, New York

Conditions: Moral Injury, Moral Distress, Post-Traumatic Stress, Nurse Well-being, Wellbeing, Wellness, Psychological, Wellness, Nurses, Nurse Health
Interventions: Surveys; Other
Lead sponsor: Mayo Clinic; Other
Eligibility: Not listed
Enrollment: 21,300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 3
States / cities: Phoenix, Arizona • Jacksonville, Florida • Rochester, Minnesota

Conditions: Cervical Cancer, Psychosocial Effects of Cancer and Its Treatment
Interventions: Psychosocial Telephone Counseling (PTC); Behavioral
Lead sponsor: University of California, Irvine; Other
Eligibility: 18 Years to 120 Years · Female only
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2007
U.S. locations: 1
States / cities: Irvine, California

Conditions: Sleep, Well-being, Mood, Mental Health, Stress (Psychology), Quality of Life, Loneliness
Interventions: Community Park Event Participation; Behavioral
Lead sponsor: City University of New York, School of Public Health; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Sarcoma
Interventions: Pocket Coach for AYA with Cancer; Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 13 Years to 25 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Stress, Drug Abuse
Interventions: Not listed
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years and older
Enrollment: 373 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2009
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Systemic Lupus Erythematosus
Interventions: Arthritis Self Management Program; Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Risk Reduction
Interventions: Information-motivation-behavior skills and cognitive processing therapy, Pre and Post HIV-Test Counseling; Behavioral
Lead sponsor: Fenway Community Health; Other
Eligibility: 18 Years and older · Male only
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 2
States / cities: Boston, Massachusetts

Conditions: Cancer
Interventions: GOLD Program, Treatment as usual (TAU); Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 8 Years to 18 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Lung Cancer, Breast Cancer, Prostate Cancer, Multiple Myeloma, Melanoma
Interventions: mHealth Intervention; Behavioral
Lead sponsor: Ohio State University Comprehensive Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Post-traumatic Stress Symptoms
Interventions: Psychosocial Intervention for Cancer-Related Post-Traumatic Stress in Young Adults; Behavioral
Lead sponsor: Zeba Ahmad, Ph.D.; Other
Eligibility: 18 Years to 39 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Stress, Depression
Interventions: Stress management; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years and older · Female only
Enrollment: 131 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2015
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Breast Cancer, Fatigue
Interventions: Iyengar Yoga, Wellness Seminar Series; Other
Lead sponsor: National Center for Complementary and Integrative Health (NCCIH); NIH
Eligibility: 40 Years to 65 Years · Female only
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Stress, Psychological, Post-Traumatic Stress Disorder, Major Injury
Interventions: DEF-only, DEF + COPE; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: Up to 5 Years
Enrollment: 57 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Stage IV Lung Cancer, Malignant Brain Tumor
Interventions: Usual care, computer-assisted intervention, Distress Thermometer, Profile of Mood States (POMS-B), Quality of Life: Functional Assessment in Cancer Therapy - (FACT), Tension-Anxiety Subscale; Procedure · Other
Lead sponsor: Case Comprehensive Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 7 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: PTSD
Interventions: trauma-focused treatment; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 178 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 3
States / cities: Boston, Massachusetts • Charleston, South Carolina • Madison, Wisconsin

Conditions: Tobacco Use Disorder, Tobacco Use Cessation, Cannabis Use, Cannabis Use Disorder, Marijuana Use
Interventions: Varenicline, Counseling, Psychosocial modules; Drug · Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Mild Cognitive Impairment, Alzheimer Disease
Interventions: Trier Social Stress Test; Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 60 Years and older
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2029
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Stress, Psychological
Interventions: Stress; Trier Social Stress Task, Placebo Trier Social Stress Task; Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years to 28 Years · Female only
Enrollment: 57 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Alcoholic Liver Disease
Interventions: Text Message; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: New Haven, Connecticut

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The New Empowerment After eXposure to Trauma (NEXT) Study

Promoting Resilience in Early Survivorship Among Adolescents and Young Adults With Cancer

Supportive Training After Cardiac Rehabilitation Including Virtual Engagement

Mosaic Trial for Stem Cell Transplant Recipients

Stress & Self-Control Costs

A Study of Moral Distress, Moral Injury and Post-Traumatic Stress for Nurses

Telephone Counseling or Standard Care in Patients Who Have Completed Treatment for Stages I, II, or III Cervical Cancer

Longitudinal Study of Neighborhood Social Event Attendance at Renovated Parks and Changes in Sleep, Stress, and Well-being

Mobile Self Management and Support for Adolescents and Young Adults With Cancer

Developing Field Tools for Real-Time Assessment of Exposure to Psychosocial Stress and Drug Use in an Outpatient Treatment Population

Balancing Lupus Experiences With Stress Strategies

HIV Prevention and Trauma Treatment in Men Who Have Sex With Men and Who Have a History of Sexual Abuse

GOLD: Brief Intervention to Reduce Anxiety and Promote Resilience in Families of Youth With Cancer

Telemedicine-mHealth Symptom Cluster Intervention for Advanced Cancer Patients: Finding Our Center Under Stress (FOCUS)

Development of a Psychosocial Intervention to Reduce Post Traumatic Stress in Young Adult Survivors of Cancer

Stress Management Intervention for Mothers of Children With Cancer

A Yoga and Wellness Program for Breast Cancer Survivors With Persistent Fatigue

Intervention to Reduce Stress in 0-5 Year Olds With Burns

A Computer-Based Intervention for Distance Caregivers of Parents With Advanced Cancer

Written Exposure Therapy Versus Prolonged Exposure: a Non-inferiority Trial

Cannabis-Tobacco Co-Use Treatment Study

Cognitive Vulnerability to Stress in Individuals at Risk for Alzheimer's Disease

Stress-Induced Inflammation and Reward Processing

Text Messaging to Reduce Alcohol Relapse in Liver Transplant Patients