Independent directory Public ClinicalTrials.gov records United States
Clear filters
ClinicalTrials.gov public records Last synced Sep 3, 2026, 5:37 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 249 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Withdrawn Not applicable Interventional Accepts healthy volunteers

SpO2 Accuracy In Vivo Testing for Neonates & Infants

NCT03843489
Conditions
Pulse Oximetry
Interventions
MEDLINE RENEWAL PULSE OXIMETRY SENSORS, Reference CO-oximetry sensor
Device
Lead sponsor
Medline Industries
Industry
Eligibility
Up to 28 Days
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Aurora, Colorado
Completed No phase listed Observational Accepts healthy volunteers

Induced Hypoxia Study for Validation of SpO2 Accuracy

NCT00788983
Conditions
Hypoxia
Interventions
Not listed
Lead sponsor
Nonin Medical, Inc
Industry
Eligibility
18 Years to 40 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
1
States / cities
San Francisco, California
Completed No phase listed Observational Accepts healthy volunteers

Dysfunctional Hemoglobin CO-ox

NCT02427685
Conditions
Elevated Levels of Carboxyhemoglobin
Interventions
Pulse Co-Ox
Device
Lead sponsor
Nonin Medical, Inc
Industry
Eligibility
18 Years to 45 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
San Francisco, California
Conditions
SpO2
Interventions
Masimo Sensor (RD SET and/or LNCS) connected to Philips Monitor using Philips FAST SpO2 Algorithm
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
0 Years to 21 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
2
States / cities
Modesto, California • San Diego, California
Conditions
Depression, Fatigue, Leukemia, Musculoskeletal Complications, Psychosocial Effects of Cancer and Its Treatment
Interventions
Resting vitals, Body Composition, Timed Get-up and Go test (TGUG)., Cardiorespiratory assessment, Handgrip evaluation, Dynamic muscular endurance
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
18 Years to 60 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Conditions
Congestive Heart Failure
Interventions
VitalCare Platform
Device
Lead sponsor
Saint Luke's Health System
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
4
States / cities
Kansas City, Kansas • Overland Park, Kansas • Kansas City, Missouri + 1 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Repeatability and Reproducibility of Oxygen Reserve Index (ORi)

NCT05636098
Conditions
Healthy
Interventions
Masimo Rainbow Sensors
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
18 Years to 50 Years
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Irvine, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

Desaturation Validation of INVSENSOR00028

NCT03704636
Conditions
Healthy
Interventions
INVSENSOR00028
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
18 Years to 50 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Irvine, California
Completed No phase listed Observational Accepts healthy volunteers

mCVI Confirmatory Clinical Study: Algorithm Verification

NCT04692064
Conditions
Algorithm Verification
Interventions
There is no intervention
Other
Lead sponsor
Intelomed, Inc.
Industry
Eligibility
21 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Cranberry Township, Pennsylvania
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

SpO2 Accuracy in Children

NCT07168798
Conditions
Hypoxemia
Interventions
Pulse oximeter
Device
Lead sponsor
Nihon Kohden
Industry
Eligibility
0 Days to 12 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Recruiting No phase listed Observational Accepts healthy volunteers

Pulse Oximeter Accuracy in Healthy Humans During Hypoxia

NCT06142019
Conditions
Hypoxia, Skin Pigmentation
Interventions
Controlled desaturation (hypoxemia)
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 50 Years
Enrollment
10,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2028
U.S. locations
1
States / cities
San Francisco, California
Completed No phase listed Interventional Accepts healthy volunteers Results available

Desaturation Validation of INVSENSOR00006

NCT03435211
Conditions
Healthy
Interventions
INVSENSOR00006
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
18 Years to 50 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Irvine, California
Conditions
Safety Issues
Interventions
Skin Group, Warmer Group
Other
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
Not listed
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Surgery
Interventions
Remote Monitoring
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Rochester, Minnesota
Completed Not applicable Interventional Accepts healthy volunteers Results available

Validation of Next Generation Cerebral and Tissue Oximeter

NCT03128372
Conditions
Oxygen Deficiency
Interventions
Desaturation
Device
Lead sponsor
Medtronic - MITG
Industry
Eligibility
18 Years to 46 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Cardiac Surgery
Interventions
Pulse Oximeter
Device
Lead sponsor
Taiwan Aulisa Medical Devices Technologies, Inc.
Industry
Eligibility
0 Days to 1 Year
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
San Francisco, California
Completed No phase listed Observational Accepts healthy volunteers Results available

Accuracy of Owlet Smart Sock Sensor 3rd Generation With Profound Hypoxia

NCT04446247
Conditions
Hypoxia
Interventions
Owlet Smart Sock Sensor 3rd Generation
Diagnostic Test
Lead sponsor
Owlet Baby Care, Inc.
Industry
Eligibility
18 Years to 49 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
San Francisco, California
Conditions
Surgery, Hemoglobin
Interventions
Pulse CO-Oximetry Technology, Blood draw
Device · Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
621 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2024
U.S. locations
1
States / cities
Sacramento, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of Tissue Oxygenation Measurement Using Multimodal Devices

NCT05784103
Conditions
Oxygen Saturation
Interventions
Clarifi Modulum, Perimed PeriFlux 5000, Apple Watch Oxygen Sensor, Innovo iP 900AP
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
2
States / cities
Indianapolis, Indiana • Pittsburgh, Pennsylvania
Conditions
Obstructive Sleep Apnea (OSA), Atrial Fibrillation (Paroxysmal), Palpitations
Interventions
Rhythm Express Wearable System
Device
Lead sponsor
VivaQuant
Industry
Eligibility
21 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
4
States / cities
Conway, Arkansas • St Louis, Missouri • Charlotte, North Carolina + 1 more
Not listed No phase listed Observational Accepts healthy volunteers

Hypoxia Blood Validation in Multiple Pulse Oximeters

NCT00881829
Conditions
Hypoxia
Interventions
Pulse Oximeter, Blood Pressure, Respiratory Rate, Respiratory Gasses, Temperature
Device
Lead sponsor
Clinimark, LLC
Other
Eligibility
18 Years to 50 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Louisville, Colorado
Conditions
Sleep-Disordered Breathing, Sleep Architecture
Interventions
Belun Ring Pulse Oximeter
Device
Lead sponsor
Belun Technology Company Limited
Other
Eligibility
18 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Redwood City, California
Conditions
Multiple Chronic Conditions
Interventions
mHealth intervention, mHealth Plus
Behavioral
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Lincoln, Nebraska
Completed No phase listed Interventional Accepts healthy volunteers Results available

Oxygen Reserve Index (ORi) Expanded Data Set Validation of INVSENSOR00025

NCT04079816
Conditions
Healthy
Interventions
INVSENSOR00025
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
18 Years to 50 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Irvine, California